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https://read.qxmd.com/read/30777558/diagnostic-analysis-of-computed-tomography-patterns-in-patients-with-invasive-pulmonary-aspergillosis-after-solid-organ-transplantation
#1
Koray Hekimoglu, Murat Haberal, Irem Serifoglu, Mahir Kirnap, Mehmet Haberal
OBJECTIVES: The aim of this study was to assess initial and follow-up computed tomography findings of invasive pulmonary aspergillosis in solid-organ transplant recipients and to examine the most common computed tomography patterns during hospitalization. MATERIALS AND METHODS: From January 2011 to September 2016, the total number of solid-organ transplant patients at our institution was 784. These patients consisted of 550 kidney, 164 liver, and 67 heart transplant recipients...
January 2019: Experimental and Clinical Transplantation
https://read.qxmd.com/read/30777223/non-vascular-interventional-radiology-in-the-paediatric-alimentary-tract
#2
Premal A Patel, Kishore Minhas, Jestine Ang, Sam Stuart, Paolo De Coppi, Ralph Gnannt
Paediatric interventional radiology is an evolving speciality which is able to offer numerous minimally invasive treatments for gastrointestinal tract pathologies. Here we describe interventions performed by paediatric interventional radiologists on the alimentary tract from the mouth to the rectum. The interventions include sclerotherapy, stricture management by dilation, stenting and adjunctive therapies such as Mitomycin C administration and enteral access for feeding, motility assessment and administration of enemas...
March 2019: European Journal of Radiology
https://read.qxmd.com/read/30774698/factors-affecting-the-concordance-of-radiologic-and-pathologic-tumor-size-in-breast-carcinoma
#3
Ameer Hamza, Sidrah Khawar, Ramen Sakhi, Ahmed Alrajjal, Shelby Miller, Warda Ibrar, Jacob Edens, Sajad Salehi, Daniel Ockner
Background: Radiologic assessment of tumor size is an integral part of the work-up for breast carcinoma. With improved radiologic equipment, surgical decision relies profoundly upon radiologic/clinical stage. We wanted to see the concordance between radiologic and pathologic tumor size to infer how accurate radiologic/clinical staging is. Materials and methods: The surgical pathology and ultrasonography reports of patients with breast carcinoma were reviewed. Data were collected for 406 cases...
February 2019: Ultrasound: Journal of the British Medical Ultrasound Society
https://read.qxmd.com/read/30773434/recanalization-of-chronic-portal-vein-occlusion-in-pediatric-liver-transplant-patients
#4
Heather Cleveland, Sheena Pimpalwar, Daniel Ashton, Alex Chau, Aaditya Nagaraj, J Alberto Hernandez
PURPOSE: To evaluate technical and clinical success and report long-term outcomes of portal vein (PV) recanalization in pediatric orthotopic liver transplant (OLT) patients with chronic PV occlusion. MATERIALS AND METHODS: This is a retrospective review of 15 OLT patients (5 males) with chronic PV occlusion who underwent PV recanalization (33 procedures) between October 2011 and February 2018. Median age was 4.5 years (range, 1-16 years); median weight was 16.6 kg (range, 11...
February 14, 2019: Journal of Vascular and Interventional Radiology: JVIR
https://read.qxmd.com/read/30771194/focal-spleen-lesions-in-visceral-leishmaniasis-a-neglected-manifestation-of-a-neglected-disease-report-of-three-cases-and-systematic-review-of-literature
#5
REVIEW
Francesca Rinaldi, Susanna Giachè, Michele Spinicci, Paola Corsi, Silvia Ambu, Giacomo Gianfaldoni, Luigi Rigacci, Umberto Arena, Alessandro Bartoloni, Lorenzo Zammarchi
BACKGROUND: The Mediterranean area is endemic for the zoonotic form of visceral leishmaniasis (VL) caused by Leishmania infantum, a species which has been recently associated with unexpected epidemiological and clinical features. METHOD: We report the result of a systematic review of the literature on VL unusually presenting with spleen focal lesions, including three previously unpublished cases. RESULTS: A total of 28 cases of VL with multiple spleen focal lesions were retrieved...
February 15, 2019: Infection
https://read.qxmd.com/read/30765072/simulation-based-training-of-the-nurse-practitioner-in-interventional-radiology
#6
Ana Echenique, Evelyn P Wempe
Advanced practice registered nurses, such as Nurse Practitioners (NPs), can be found working in a variety of settings. Niche practices, such as Interventional Radiology, are highly specialized areas and are often specialties in which few NPs get to orient through during their graduate nursing program clinical rotations. For the NP transitioning into an Interventional Radiology practice, formal on-the-job orientation and training can assist in gaining specialty-based knowledge and competencies in performing interventional procedures...
March 2019: Techniques in Vascular and Interventional Radiology
https://read.qxmd.com/read/30763229/percutaneous-irreversible-electroporation-for-the-treatment-of-small-renal-masses-the-first-canadian-case-series
#7
Bonnie Liu, Jordyn Clark, Trustin Domes, Chris Wall, Kunal Jana
INTRODUCTION: Irreversible electroporation (IRE) is a novel technology used in the minimally invasive treatment of small solid organ tumours. Currently, there is a paucity of literature studying treatment of small renal masses (SRMs) with IRE. Our pilot study is the first case series in Canada to use IRE in the treatment of SRMs. METHODS: This retrospective cohort pilot study includes five patients (three females and two males) who presented with a SRM that was deemed not amendable to any other treatment than a radical nephrectomy or IRE...
January 21, 2019: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://read.qxmd.com/read/30762113/imaging-features-of-smarca4-deficient-thoracic-sarcomas-a-multi-centric-study-of-21-patients
#8
Amandine Crombé, Nicolas Alberti, Nicolas Villard, Frank Pilleul, Xavier Buy, François Le Loarer, Michèle Kind
OBJECTIVES: SMARCA4-deficient thoracic sarcoma (SMARCA4-DTS) is a recently identified aggressive subtype of sarcoma. The aim of this study was to characterize the CT imaging features of SMARCA4-DTS. METHODS: From June 2011 to May 2017, 21 adult patients with histologically proven SMARCA4-DTS were identified in the radiological database of 2 French sarcoma reference centers with at least one chest CT scan available. The locations, sizes, heterogeneity, margin definitions, and local extensions of the tumors were reported together with their impact on surrounding organs and regional and distant metastases...
February 14, 2019: European Radiology
https://read.qxmd.com/read/30758265/laparoscopic-diamond-antroduodenostomy-for-postcorrosive-pyloric-cicatrization-a-novel-approach
#9
Hamed M Seleim, Ahmed M K Wishahy, Mohamed H Abouelfadl, Moemen M Farouk, Khalid Elshimy, Ahmed E Fares, Sherif N Kaddah, Gamal Eltagy, Mohamed M Elbarbary
BACKGROUND: Traditionally, Billroth I procedure or bypass gastrojejunostomy were the recommended approaches for management of postcorrosive complete gastric outlet obstruction (GOO), whereas Heineke Mickulicz pyloroplasty was recommended for moderate mucosal injury with partial cicatrization. In this study, laparoscopic diamond antroduodenostomy was carried out as an alternative minimally invasive approach for cases with pyloric cicatricial obstruction. PATIENTS AND METHODS: Between January and December 2017, children who were referred to Pediatric Surgery Department, Cairo University Hospital, with GOO as a consequence of caustic liquid ingestions were included in this study...
February 13, 2019: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://read.qxmd.com/read/30753637/awake-surgical-management-of-third-ventricular-tumors-a-preliminary-safety-feasibility-and-clinical-applications-study
#10
Srikant S Chakravarthi, Amin B Kassam, Melanie B Fukui, Alejandro Monroy-Sosa, Nichelle Rothong, Joseph Cunningham, Jonathan E Jennings, Neil Guenther, Jeremy Connelly, Tobias Kaemmerer, Kenneth C Nash, Mark Lindsay, Janie Rissell, Juanita M Celix, Richard A Rovin
BACKGROUND: Endoscopic and microneurosurgical approaches to third ventricular lesions are commonly performed under general anesthesia. OBJECTIVE: To report our initial experience with awake transsulcal parafascicular corridor surgery (TPCS) of the third ventricle and its safety, feasibility, and limitations. METHODS: A total of 12 cases are reviewed: 6 colloid cysts, 2 central neurocytomas, 1 papillary craniopharyngioma, 1 basal ganglia glioblastoma, 1 thalamic glioblastoma, and 1 ependymal cyst...
February 12, 2019: Operative Neurosurgery (Hagerstown, Md.)
https://read.qxmd.com/read/30753590/use-of-aspergillus-fumigatus-real-time-pcr-in-bronchoalveolar-lavage-samples-bal-for-diagnosis-of-invasive-aspergillosis-including-azole-resistant-cases-in-high-risk-haematology-patients-the-need-for-a-combined-use-with-galactomannan
#11
Malgorzata Mikulska, Elisa Furfaro, Elena De Carolis, Enrico Drago, Ilaria Pulzato, Maria Lucia Borghesi, Emanuela Zappulo, Anna Maria Raiola, Carmen Di Grazia, Valerio Del Bono, Giuseppe Cittadini, Emanuele Angelucci, Maurizio Sanguinetti, Claudio Viscoli
Diagnosis of invasive aspergillosis (IA) is challenging, particularly in high-risk patients with lung lesions other than typical according to 2008-EORTC/MSG criteria. Even if microbiology is positive, they still remain unclassified according to 2008-EORTC/MSG. Quantitative polymerase chain reaction (qPCR) provides new mycological documentation of IA. This retrospective study assessed Aspergillus fumigatus real time qPCR (MycoGENIE®) in BAL to diagnose IA and identify azole-resistant strains. Clinical, radiological, and microbiological data from 114 hematology patients (69% HSCT recipients; 29% on mould active agents) from years 2012-2017 were collected; and 123 BAL samples were tested with qPCR (cutoff: Ct < 40) and galactomannan (GM, Platelia®, cutoff: 0...
February 7, 2019: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://read.qxmd.com/read/30741755/neutropenic-enterocolitis-in-critically-ill-patients-spectrum-of-the-disease-and-risk-of-invasive-fungal-disease
#12
Baptiste Duceau, Muriel Picard, Romain Pirracchio, Anne Wanquet, Frédéric Pène, Sybille Merceron, Djamel Mokart, Anne-Sophie Moreau, Etienne Lengliné, Emmanuel Canet, Virginie Lemiale, Eric Mariotte, Elie Azoulay, Lara Zafrani
OBJECTIVES: Neutropenic enterocolitis occurs in about 5.3% of patients hospitalized for hematologic malignancies receiving chemotherapy. Data from critically ill patients with neutropenic enterocolitis are scarce. Our objectives were to describe the population of patients with neutropenic enterocolitis admitted to an ICU and to investigate the risk factors of invasive fungal disease. DESIGN: A multicentric retrospective cohort study between January 2010 and August 2017...
February 7, 2019: Critical Care Medicine
https://read.qxmd.com/read/30740685/multimodal-imaging-assessment-and-histologic-correlation-of-the-female-rat-pelvic-floor-muscles-anatomy
#13
Vipul R Sheth, Pamela Duran, Jonathan Wong, Sameer Shah, Jiang Du, Karen L Christman, Eric Y Chang, Marianna Alperin
Pelvic floor disorders negatively impact millions of women worldwide. Although there is a strong epidemiological association with childbirth, the mechanisms leading to the dysfunction of the integral constituents of the female pelvic floor, including pelvic floor skeletal muscles, are not well understood. This is in part due to the constraints associated with directly probing these muscles, which are located deep in the pelvis. Thus, experimental models and non-invasive techniques are essential for advancing knowledge of various phenotypes of pelvic floor muscle injury and pathogenesis of muscle dysfunction, as well as developing minimally invasive approaches for the delivery of novel therapeutics...
February 10, 2019: Journal of Anatomy
https://read.qxmd.com/read/30739374/early-detection-of-the-pax3-foxo1-fusion-gene-in-circulating-tumor-derived-dna-in-a-case-of-alveolar-rhabdomyosarcoma
#14
Minenori Eguchi-Ishimae, Mari Tezuka, Tomoki Kokeguchi, Kozo Nagai, Kyoko Moritani, Sachiko Yonezawa, Hisamichi Tauchi, Kiriko Tokuda, Yasushi Ishida, Eiichi Ishii, Mariko Eguchi
Cell-free DNA (cfDNA), which are small DNA fragments in blood derived from dead cells including tumor cells, could serve as useful biomarkers and provide valuable genetic information about the tumors. cfDNA is now used for the genetic analysis of several types of cancers, as a surrogate for tumor biopsy, designated as "liquid biopsy." Rhabdomyosarcoma (RMS), the most frequent soft tissue tumor in childhood, can arise in any part of the body, and radiological imaging is the only available method for estimating the tumor burden, because no useful specific biological markers are present in the blood...
February 10, 2019: Genes, Chromosomes & Cancer
https://read.qxmd.com/read/30738077/combined-locoregional-immunotherapy-for-liver-cancer
#15
REVIEW
Tim F Greten, Michal Mauda-Havakuk, Bernd Heinrich, Firouzeh Korangy, Bradford J Wood
Locoregional therapies are commonly used to treat patients with hepatocellular carcinoma. It has been noted for many years that locoregional therapies may have additional systemic effects other than simple tumor elimination. Immunological "side effects" have been described in response to locoregional therapies in animal studies and also in patients. With the advent of immunotherapy for hepatocellular carcinoma, there is an increasing interest in understanding how immunotherapy may be best combined with locoregional therapies...
February 6, 2019: Journal of Hepatology
https://read.qxmd.com/read/30737321/more-than-meets-the-eye
#16
Ailbhe White-Gibson, Paul Lennon, Esther O'Regan, Conrad Timon
We report an extremely rare case of a hybrid tumour of the maxillary sinus. A 51-year-old man presented with a 6-week history of nasal congestion and epiphora. Radiological imaging demonstrated a maxillary sinus tumour, with extensive local invasion. Surgical excision included maxillectomy, left eye exenteration and free flap closure. Histology of the excised specimen showed a rare hybrid tumour containing adenoid cystic carcinoma, salivary duct carcinoma, epithelial-myoepithelial carcinoma and basal cell adenoma...
February 7, 2019: BMJ Case Reports
https://read.qxmd.com/read/30723019/the-size-of-well-differentiated-pancreatic-neuroendocrine-tumors-correlates-with-ki67-proliferative-index-and-is-not-associated-with-age
#17
Stefano Partelli, Francesca Muffatti, Paola Maria Vittoria Rancoita, Valentina Andreasi, Gianpaolo Balzano, Stefano Crippa, Claudio Doglioni, Corrado Rubini, Giuseppe Zamboni, Massimo Falconi
BACKGROUND: Concerns exist about a conservative management of well-differentiated nonfunctioning small pancreatic neuroendocrine tumors (NF-PanNET) in young patients and when preoperative Ki67 proliferative index is ≥3%. AIM: To evaluate an association between age, tumor size and grading in patients with sporadic NF-PanNET who underwent curative resection. METHODS: Patients who underwent surgery for sporadic NF-PanNET (excluding G3) were retrospectively analyzed...
January 22, 2019: Digestive and Liver Disease
https://read.qxmd.com/read/30722105/aspergillosis-in-immunocompromised-patients-with-haematological-malignancies
#18
Eleftheria Gletsou, Maria Ioannou, Vasileios Liakopoulos, Evangelos Tsiambas, Vasileios Ragos, Ioannis Stefanidis
Aspergillosis, which is saprophytic in nature, is known to cause massive destruction of paranasal sinuses in immunocompromised hosts, but in immunocompetent individuals invasive aspergillosis is rare. Diagnosis is posed from history, physical examination including anterior and posterior rhinoscopy, endoscopy of the nose and paranasal sinuses, radiological findings (CT and/or MRI), fungus cultures and histopathological examination. Non-specific presenting symptoms provide time for infection to extent from sinuses to vital surroundings such as bony, vascular and central nervous system structures, thereby increasing morbidity and mortality...
December 2018: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://read.qxmd.com/read/30717981/non-invasive-three-dimensional-bone-vessel-image-fusion-using-black-bone-mri-based-on-fiesta-c
#19
T Hayashi, N Fujima, A Hamaguchi, T Masuzuka, K Hida, S Kodera
AIM: To evaluate the image quality of bone-vessel fused volume-rendering (VR) images reconstructed by three-dimensional "black bone" magnetic resonance imaging (MRI) based on the fast imaging employing steady-state acquisition cycled phases (FIESTA-C) sequence and time-of-flight magnetic resonance angiography (TOF-MRA). MATERIALS AND METHODS: Seventeen patients were analysed in this retrospective study. All patients underwent both MRI techniques including FIESTA-C and TOF-MRA and computed tomography angiography (CTA)...
February 1, 2019: Clinical Radiology
https://read.qxmd.com/read/30712050/survival-and-metastasis-in-muscle-invasive-bladder-cancer-patients-who-present-with-indeterminate-pulmonary-nodules-before-treatment
#20
Ali Al-Daghmin, Sohaib Alhamss, Hani Al-Najjar, Ibrahim Al-Saidi, Khloud Al-Qasem, Ibrahim Abukhiran, Anas Hamad, Muna Alhusban
BACKGROUND: Indeterminate pulmonary nodules (IPNs) are common during initial evaluation of bladder cancer patients. Their significance is still unknown. OBJECTIVE: Determine the significance of indeterminate pulmonary nodules, including their size and number, in muscle-invasive bladder cancer patients before definitive local therapy by surgery or chemo-radiotherapy. DESIGN: Retrospective review, single-center descriptive study. SETTINGS: A tertiary cancer center...
January 2019: Annals of Saudi Medicine
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