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Deformable Segmentation

Takayoshi Shimizu, Suthipas Pongmanee, K Daniel Riew
PURPOSE: To investigate the normative value of distance between the spinous processes (inter-spinous process distance, ISPD), correlations between patients' demographics and ISPD, and determine cutoff ISPD values that result in segmental lordosis in posterior cervical-thoracic arthrodesis with instrumentation. METHODS: We reviewed patients with visible lower cervical and cervicothoracic spinous processes (C5-T2) on dynamic X-rays. Radiographic measurements included segmental Cobb angles (S-Cobb) and ISPD, defined as the distance between midpoints of the spinous processes...
February 15, 2019: European Spine Journal
Mariana M Lamacie, Christian P Houbois, Andreas Greiser, Marie-Pierre Jolly, Paaladinesh Thavendiranathan, Bernd J Wintersperger
OBJECTIVES: To validate deformable registration algorithms (DRAs) for cine balanced steady-state free precession (bSSFP) assessment of global longitudinal strain (GLS) and global circumferential strain (GCS) using harmonic phase (HARP) cardiovascular magnetic resonance as standard of reference (SoR). METHODS: Seventeen patients and 17 volunteers underwent short axis stack and 2-/4-chamber cine bSSFP imaging with matching slice long-axis and mid-ventricular spatial modulation of magnetization (SPAMM) myocardial tagging...
February 15, 2019: European Radiology
Gleison D P Bossolani, Isabel Pintelon, Jan D Detrez, Roeland Buckinx, Sofie Thys, Jacqueline Nelisis Zanoni, Winnok H De Vos, Jean-Pierre Timmermans
BACKGROUND: The intestinal wall has a complex topographical architecture. The multi-layered network of the enteric nervous system and its intercellular interactions are difficult to map using traditional section-based or whole-mount histology. With the advent of optical clearing techniques, it has become feasible to visualize intact tissue and organs in 3D. However, as yet, a gap still needs to be filled in that no in-depth analysis has been performed yet on the potential of different clearing techniques for the small intestine...
February 13, 2019: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
Xiaofang Shen, Fei Yin, Mingyu Xue, Jiong Yu, Weifeng Lin, Yongjun Rui
Objective: To explore the effectiveness of one-stage metacarpal osteotomy, thumb opponensplasty and polygonal flap reconstruction in the treatment of congenital spade hand deformity. Methods: Eight cases of congenital spade hand were treated between January 2013 and March 2017. There were 5 males and 3 females, with an average age of 17.5 months (range, 13-35 months). The clinical manifestations of all the children were congenital spade hand and the affected hand was shorter than the healthy side...
February 1, 2019: Chinese Journal of Reparative and Reconstructive Surgery
Alpaslan Senkoylu, Mehmet Cetinkaya, Erdem Aktas, Engin Cetin
We report the surgical treatment course of a 4-year-old girl with congenital scoliosis, diastematomyelia and double adjacent hemivertebrae. She had a lumbar curve with an apparent pelvic obliquity. Simultaneous excision of double segmented sequential hemivertebra at the L3-L4 level and fusion with short-segment instrumentation was performed via a posterior approach. Intraoperative radiographs revealed satisfactory curve correction and 0° pelvic obliquity. Following the excision of double adjacent hemivertebrae, three adjacent nerve roots were placed in one intervertebral foramen bilaterally...
February 1, 2019: Acta Orthopaedica et Traumatologica Turcica
Guha Balakrishnan, Amy Zhao, Mert R Sabuncu, John Guttag, Adrian V Dalca
We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical image registration. Traditional registration methods optimize an objective function for each pair of images, which can be time-consuming for large datasets or rich deformation models. In contrast to this approach, and building on recent learning-based methods, we formulate registration as a function that maps an input image pair to a deformation field that aligns these images. We parameterize the function via a convolutional neural network (CNN), and optimize the parameters of the neural network on a set of images...
February 4, 2019: IEEE Transactions on Medical Imaging
Steffen Lukas, Sarah Feger, Matthias Rief, Elke Zimmermann, Marc Dewey
OBJECTIVES: To propose and evaluate a four-dimensional (4D) algorithm for joint motion elimination and spatiotemporal noise reduction in low-dose dynamic myocardial computed tomography perfusion (CTP). METHODS: Thirty patients with suspected or confirmed coronary artery disease were prospectively included and underwent dynamic contrast-enhanced 320-row CTP. A novel deformable image registration method based on the principal component analysis (PCA) of the ante hoc temporally smoothed voxel-wise time-attenuation curves (ASTRA4D) is presented...
February 4, 2019: European Radiology
Saraswathy Gnanasundaram, Priyadharshini Ramalingam, Bhabendra Nath Das, Vijay Viswanathan
Background Increasing prevalence of diabetic foot ulcer (DFU) and subsequent foot amputation in persons with type 2 diabetic neuropathy is a well known fact. The present study was aimed to identify the initial risk marker for DFU. Methods Dynamic plantar pressure analysis was done for persons with type 2 diabetes mellitus (T2DM) without neuropathy (D), patients with diabetic neuropathy (DN) with normal foot profile and healthy persons with normal foot profile (C). Results The data showed a significant difference in dynamic peak plantar pressure between C and DN (P = 0...
January 26, 2019: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Murat Korkmaz, Turgut Akgul, Kerim Sariyilmaz, Okan Ozkunt, Fatih Dikici, Onder Yazicioglu
INTRODUCTION: Proximal junctional kyphosis - PJK has been defined by a 10 or greater increase in kyphosis at the proximal junction as measured by the Cobb angle from the caudal endplate of the uppermost instrumented vertebrae (UIV) to the cephalad endplate of the vertebrae 1 segments cranial to the UIV. In this biomechanical study, it is aimed to evaluate effects of interspinosus ligament complex distruption and facet joint degeneration on PJK development. MATERIALS AND METHODS: Posterior instrumentation applied between T2 - T7 vertebrae using pedicle screws to randomly selected 21 sheeps, divided into 3 groups...
January 30, 2019: Acta Orthopaedica et Traumatologica Turcica
P Sh Chomakhidze, N V Mozzhuhina, M G Poltavskaya, V P Sedov, A L Syrkin
PURPOSE OF THE STUDY: Evaluation of the value of the results of the use of cardiac functional examination methods for the stratification of the risk of developing cardiovascular complications in planned abdominal surgical interventions in patients over 65 years of age or with cardiac pathology. MATERIALS AND METHODS: The study included 179 patients over 65 years of age or with a history of heart disease who underwent elective abdominal surgery. The median age was 70 years...
January 28, 2019: Kardiologiia
M M Chaudhary, P H Lakhani
AIMS: Double-level lengthening, bone transport, and bifocal compression-distraction are commonly undertaken using Ilizarov or other fixators. We performed double-level fixator-assisted nailing, mainly for the correction of deformity and lengthening in the same segment, using a straight intramedullary nail to reduce the time in a fixator. PATIENTS AND METHODS: A total of 23 patients underwent this surgery, involving 27 segments (23 femora and four tibiae), over a period of ten years...
February 2019: Bone & Joint Journal
P W H Cheung, H K Fong, C S Wong, J P Y Cheung
AIMS: The aim of this study was to determine the influence of developmental spinal stenosis (DSS) on the risk of re-operation at an adjacent level. PATIENTS AND METHODS: This was a retrospective study of 235 consecutive patients who had undergone decompression-only surgery for lumbar spinal stenosis and had a minimum five-year follow-up. There were 106 female patients (45.1%) and 129 male patients (54.9%), with a mean age at surgery of 66.8 years (sd 11.3). We excluded those with adult deformity and spondylolisthesis...
February 2019: Bone & Joint Journal
Hirohito Kan, Yuta Eguchi, Takahiro Tsuchiya, Takuto Kondo, Yuto Kitagawa, Yuji Mekata, Hiroshi Fukuma, Ryoya Yoshida, Harumasa Kasai, Hiroshi Kunitomo, Yasujiro Hirose, Yuta Shibamoto
MR-only simulations provide pseudo-CT images which are segmented into 5 kinds of tissues from DIXON-based images. However, it is difficult to register pseudo-CT images to cone-beam CT (CBCT) images collected for image-guided radiation therapy (IGRT), because of the lack of contrasts among tissues. We validated gaps of IGRT between pseudo-CT or planning CT and CBCT for patients without implanted markers. We also propose calcification-assisted registration for MR-only simulation.
 We conducted retrospective analyses to verify the registration accuracy in 15 patients who underwent volumetric modulated arc therapy for prostate cancer...
January 29, 2019: Physics in Medicine and Biology
Ayush Goyal
A rapid method for left and right ventricular endocardial volume segmentation and clinical cardiac parameter calculation from MRI images of cardiac patients is presented. The clinical motivation is providing cardiologists a tool for assessing the cardiac function in a patient through the left ventricular endocardial volume's ejection fraction. A new method combining adapted fuzzy membership-based c-means pixel clustering and connected regions component labeling is used for automatic segmentation of the left and right ventricular endocardial volumes...
January 28, 2019: Medical & Biological Engineering & Computing
Lauren E Kokai, Benjamin K Schilling, Evangelia Chnari, Yen-Chen Huang, Emily A Imming, Arivarasan Karunamurthy, Roger K Khouri, Richard A D'Amico, Sydney R Coleman, Kacey G Marra, J Peter Rubin
BACKGROUND: Adipose tissue reaches cellular stasis after puberty, leaving adipocytes unable to significantly expand or renew under normal physiologic conditions. This is problematic in progressive lipodystrophies, in instances of scarring, and in soft-tissue damage resulting from lumpectomy and traumatic deformities, because adipose tissue will not self-renew once damaged. This yields significant clinical necessity for an off-the-shelf de novo soft-tissue replacement mechanism. METHODS: A process comprising separate steps of removing lipid and cellular materials from adipose tissue has been developed, creating an ambient temperature-stable allograft adipose matrix...
February 2019: Plastic and Reconstructive Surgery
Bhargav D Desai, Davis G Taylor, Ching-Jen Chen, Thomas J Buell, Jeffrey P Mullin, Bhiken I Naik, Justin S Smith, Christopher I Shaffrey
Tranexamic acid (TXA) is an antifibrinolytic agent with demonstrated efficacy in reducing blood loss when administered systemically. However, in patients with contraindications to systemic or intravenous TXA, topical TXA (tTXA) has been shown to reduce perioperative blood loss, with some studies suggesting equivalence compared to systemic TXA. However, these studies have been conducted in healthy cohorts without contraindications to systemic TXA. In the surgical management of adult spinal deformity (ASD), comorbid disease is commonly encountered and may preclude use of systemic TXA...
January 25, 2019: Journal of Neurosurgery. Spine
Han Jo Kim, Byung-Wan Choi, JeaSeok Park, Sebastien Pesenti, Virginie Lafage
OBJECTIVE: The purpose of this study was to evaluate its effect on the restoration and maintenance of cervical sagittal alignment in usual cervical degenerative diseases without preoperative sagittal malalignment. MATERIALS AND METHODS: We retrospectively evaluated 108 patients who were diagnosed with degenerative cervical disease and underwent ACDF (allograft and plating) with > 1-year follow-up. For radiographic evaluation, we analysed segmental and C2-7 cervical lordosis, disc height, C2-7 sagittal vertical axis (SVA), T1 slope, and T1 slope minus C2-7 lordosis (T1S - CL) in lateral X-ray...
January 25, 2019: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
Ting-Yan Xu, Yan Yang, Jing-Jing Li, Yan Li, Ji-Guang Wang
This study aimed to evaluate left ventricular deformation in relation to the geometric pattern in hypertensive patients with normal left ventricular ejection fraction using speckle tracking echocardiography (STE).Transthoracic echocardiography was performed in 80 hypertensive patients and 50 age- and gender-matched normotensive subjects. Left ventricular geometric pattern was defined according to left ventricular mass index and relative wall thickness as normal geometry, concentric remodeling, concentric hypertrophy, and eccentric hypertrophy, respectively...
January 2019: Medicine (Baltimore)
Sofia Levin, Noa Sela, Tal Erez, David Nestel, Jeffery Pettis, Peter Neumann, Nor Chejanovsky
Varroa destructor is an ectoparasitic mite of Asian or Eastern honeybees Apis cerana (A. cerana) which has become a serious threat to European subspecies of Western honeybees Apis mellifera ( A. mellifera ) within the last century. V. destructor and its vectored honeybee viruses became serious threats for colony survival. This is a short period for pathogen- and host-populations to adapt. To look for possible variation in the composition of viral populations we performed RNA metagenomic analysis of the Western honeybee subspecies A...
January 24, 2019: Viruses
Kazuya Kobayashi, Satoru Wakasa, Koji Sato, Satoshi Kanai, Hiroaki Date, Satomi Kimura, Noriko Oyama-Manabe, Yoshiro Matsui
Regional cardiac function analysis is important for the diagnosis and treatment planning of ischemic heart disease, but has not been sufficiently developed in the field of computed tomography (CT). Therefore, we propose a three-dimensional endocardial tracking framework for cardiac CT using local point cloud registration based on the iterative closest point with an integrated scale estimation algorithm. We also introduce regional function descriptors that express the curvature and stretching of the endocardium: Surface distortion (E) and Scaling rate (S)...
January 22, 2019: Physics in Medicine and Biology
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