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Diabetes or Hypertension and Heart Failure

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https://read.qxmd.com/read/30758702/regional-differences-in-patient-characteristics-and-outcomes-during-uninterrupted-anticoagulation-with-dabigatran-versus-warfarin-in-catheter-ablation-of-atrial-fibrillation-the-re-circuit-study
#1
Stefan H Hohnloser, Hugh Calkins, Stephan Willems, Atul Verma, Richard Schilling, Ken Okumura, Matias Nordaby, Eva Kleine, Branislav Biss, Edward P Gerstenfeld
PURPOSE: To describe regional differences in patient characteristics, ablation procedures, and bleeding events in the RE-CIRCUIT study. RE-CIRCUIT was a prospective, multicenter study that captured data from different regions, providing an opportunity to understand the practices followed in various regions. The incidence of major bleeding events (MBEs) was significantly lower with uninterrupted dabigatran versus uninterrupted warfarin. METHODS: Patients were randomized to receive dabigatran 150 mg twice daily or warfarin...
February 13, 2019: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://read.qxmd.com/read/30747633/specific-factors-predict-the-risk-for-urgent-and-emergent-colectomy-in-patients-undergoing-surgery-for-diverticulitis
#2
Neda Valizadeh, Kunal Suradkar, Ravi P Kiran
The aim of this study was to identify preoperative characteristics that may determine the need for emergency surgery for diverticulitis and assess postoperative outcomes for these patients when compared with elective surgery. All patients included in the ACS-NSQIP-targeted colectomy database from 2012 to 2013 who underwent colectomy with an underlying diagnosis of diverticulitis were included. Preoperative characteristics and 30-day postoperative outcomes were evaluated for patients who underwent elective versus emergent/urgent surgery using univariable and multivariable analyses...
November 1, 2018: American Surgeon
https://read.qxmd.com/read/30742823/severe-cardiovascular-morbidity-in-women-with-hypertensive-diseases-during-delivery-hospitalization
#3
Christina M Ackerman, Marissa H Platner, Erica S Spatz, Jessica L Illuzzi, Xiao Xu, Katherine H Campbell, Graeme N Smith, Michael J Paidas, Heather S Lipkind
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of pregnancy-related death in the United States. (1) Identification of short-term indicators of cardiovascular morbidity has the potential to alter the course of this devastating disease among women. It has been established that hypertensive disorders of pregnancy (HDP) are associated with increased risk of cardiovascular disease 10-30 years after delivery; however, little is known about the association of hypertensive disorders of pregnancy with cardiovascular (CV) morbidity during the delivery hospitalization...
February 8, 2019: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/30739421/-long-term-results-of-chest-wall-arteriovenous-graft-for-establishing-hemodialysis-access
#4
Kang She, Xiansheng Zhang, Jie Yin, Gong Cheng, Xiangrong Chen
Objective: To explore the role of chest wall arteriovenous graft (CWAVG) for establishing hemodialysis access in patients with end-stage renal disease. Methods: A retrospective analysis was made on the clinical data of 12 patients with end-stage renal disease who underwent CWAVG for establishing hemodialysis access between January 2014 and June 2015. There were 3 males and 9 females with an average age of 63.6 years (range, 54-82 years). The renal disease causes were chronic glomerulonephritis in 2 cases, hypertensive renal damage in 4 cases, diabetic nephropathy in 1 case, both kidney resection because of urinary tract tumors in 3 cases, and causes unknown in 2 cases...
February 1, 2019: Chinese Journal of Reparative and Reconstructive Surgery
https://read.qxmd.com/read/30737767/trial-of-labor-after-cesarean-section-in-risk-pregnancies-a-population-based-cohort-study
#5
Sjur Lehmann, Elham Baghestan, Per Engebret Børdahl, Lorentz Muller Irgens, Svein Arvid Rasmussen
INTRODUCTION: In most pregnancies after a cesarean section, a trial of labor is an option. The objective of the study was to explore trial of labor and its failure in pregnancies with medical risk conditions, in a population with a high trial of labor rate. MATERIAL AND METHODS: In a cohort study (n=57 109), using data from the Medical Birth Registry of Norway 1989-2014, women with a second delivery after a first pregnancy cesarean section were included. Preterm, multiple, and non-cephalic deliveries were excluded...
February 8, 2019: Acta Obstetricia et Gynecologica Scandinavica
https://read.qxmd.com/read/30724129/electroceutical-targeting-of-the-autonomic-nervous-system
#6
Charles C Horn, Jeffrey L Ardell, Lee E Fisher
Autonomic nerves are attractive targets for medical therapies using electroceutical devices because of the potential for selective control and few side effects. These devices use novel materials, electrode configurations, stimulation patterns, and closed-loop control to treat heart failure, hypertension, gastrointestinal and bladder diseases, obesity/diabetes, and inflammatory disorders. Critical to progress is a mechanistic understanding of multi-level controls of target organs, disease adaptation, and impact of neuromodulation to restore organ function...
March 1, 2019: Physiology
https://read.qxmd.com/read/30717885/usefulness-of-left-ventricular-strain-by-cardiac-magnetic-resonance-feature-tracking-to-predict-cardiovascular-events-in-patients-with-and-without-heart-failure
#7
Mayank Sardana, Prasad Konda, Zeba Hashmath, Garrett Oldland, Swetha Gaddam, Rachana Miller, Vaibhav Satija, Bilal Ansari, Jonathan Lee, Anique Mustafa, Scott R Akers, Julio A Chirinos
There is controversy regarding the utility of left ventricular (LV) mechanics assessed by feature-tracking steady-state free-precession (FT-SSFP), a readily implementable technique in clinical practice. In particular, whether LV mechanics assessed by FT-SSFP predicts outcomes in subjects with heart failure (HF) with reduced ejection fraction (HFrEF), with preserved ejection fraction (HFpEF), or without HF is unknown. We aimed to assess whether LV mechanics measured with FT-SSFP cine magnetic resonance imaging (MRI) predicts adverse outcomes...
January 25, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30717670/association-between-coronary-dominance-and-acute-inferior-myocardial-infarction-a-matched-case-control-study
#8
Li Wang, Jiamei Li, Ya Gao, Ruohan Li, Jingjing Zhang, Dan Su, Tao Wang, Guang Yang, Xiaochuang Wang
BACKGROUND: Previous studies have found a connection between left coronary artery dominance and worse prognoses in patient with acute coronary syndrome, which remains a predominant cause of morbidity and mortality globally. The aim of this study was to investigate whether coronary dominance is associated with the incidence of acute inferior myocardial infarction (MI). METHODS: Between January 2011 and November 2014, 265 patients with acute inferior MI and 530 age-matched and sex-matched controls were recruited for a case-control study in the Second Affiliated Hospital of Xi'an Jiaotong University in Xi'an, China...
February 4, 2019: BMC Cardiovascular Disorders
https://read.qxmd.com/read/30715404/the-risk-of-heart-failure-and-other-cardiovascular-hospitalizations-after-early-stage-breast-cancer-a-matched-cohort-study
#9
Husam Abdel-Qadir, Paaladinesh Thavendiranathan, Peter C Austin, Douglas S Lee, Eitan Amir, Jack V Tu, Kinwah Fung, Geoffrey M Anderson
Background: Data are limited regarding the risk of heart failure (HF) requiring hospital-based care after early stage breast cancer (EBC) and its relationship to other types of cardiovascular disease (CVD). Methods: We conducted a population-based, retrospective cohort study of EBC patients (diagnosed April 1, 2005-March 31, 2015) matched 1:3 on birth-year to cancer-free control subjects. We identified hospitalizations and emergency department visits for CVD through March 31, 2017...
January 31, 2019: Journal of the National Cancer Institute
https://read.qxmd.com/read/30712418/obesity-related-heart-failure-with-preserved-ejection-fraction-new-treatment-strategies
#10
Steven G Chrysant, George S Chrysant
OBJECTIVES: Obesity has risen in the US and worldwide, and has become a major risk factor for type 2 diabetes mellitus (T2DM), hypertension, cardiovascular disease, and heart failure (HF), mostly HF with preserved ejection fraction (HFpEF). Also, the prevalence of HF is quite high in the US accounting for 6.6 million adults at present and is projected to reach 8.5 million by the year 2030 and is equally divided between HFpEF and heart failure reduced ejection fraction (HFrEF). Patients with HFpEF are resistant to treatment with drugs usually used for the treatment of HFrEF, but the reasons for this resistance are not clearly known...
February 4, 2019: Hospital Practice (Minneapolis)
https://read.qxmd.com/read/30712076/use-of-left-atrial-appendage-occlusion-among-older-cardiac-surgery-patients-with-preoperative-atrial-fibrillation-a-national-cohort-study
#11
Daniel J Friedman, Jeffrey G Gaca, Tongrong Wang, S Chris Malaisrie, David R Holmes, Jonathan P Piccini, Rakesh M Suri, Michael J Mack, Vinay Badhwar, Jeffrey P Jacobs, Eric D Peterson, Shein-Chung Chow, J Matthew Brennan
PURPOSE: Patients with atrial fibrillation (AF) undergoing cardiac surgery are at substantially increased risk for stroke. Increasing evidence has suggested that surgical left atrial appendage occlusion (S-LAAO) may have the potential to substantially mitigate this stroke risk; however, S-LAAO is performed in a minority of patients with AF undergoing cardiac surgery. We sought to identify factors associated with usage of S-LAAO. METHODS: In a nationally-representative, contemporary cohort (07/2011-06/2012) of older patients undergoing cardiac surgery with preoperative AF (n = 11,404) from the Medicare-linked Society of Thoracic Surgeons Adult Cardiac Surgery Database, we evaluated patient and hospital characteristics associated with S-LAAO use by employing logistic and linear regression models...
February 2, 2019: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://read.qxmd.com/read/30709867/a-novel-angiotensin-1-7-glycosylated-mas-receptor-agonist-for-treating-vascular-cognitive-impairment-and-inflammation-related-memory-dysfunction
#12
Meredith Hay, Robin Polt, Michael L Heien, Todd W Vanderah, Tally M Largen-Milnes, Kathleen E Rodgers, Torsten Falk, Mitchell J Bartlett, Kristian Doyle, John Konhilas
A growing body of evidence indicates that decreased brain blood flow, increased reactive oxygen species production (ROS), and pro-inflammatory mechanisms accelerate the progression of neurodegenerative diseases such as vascular contributions to cognitive impairment and dementia (VCID) and Alzheimer's disease and related dementias (ADRD). There is an urgent clinical need for safe and effective therapies for the treatment and prevention of cognitive impairment known to occur in patients with VCID and chronic inflammatory diseases such as heart failure (HF), hypertension and diabetes...
February 1, 2019: Journal of Pharmacology and Experimental Therapeutics
https://read.qxmd.com/read/30706096/effect-of-benign-prostatic-hyperplasia-on-the-development-of-spine-hip-and-wrist-fractures
#13
S C Yang, Y C Chiu, P H Liu, T J Hsieh, Y H Kao, Y K Tu
Benign prostatic hyperplasia is one of the most common diseases in the elderly male population. The urinary tract symptoms may increase the risk of falls and fractures. The results indicated that patients with benign prostatic hyperplasia could increase the risk of vertebral compression fractures in both the thoracic and lumbar spine and also hip fractures, but did not increase the risk of wrist fracture. INTRODUCTION: The relationship between benign prostatic hyperplasia and the development of fall-related fractures, especially vertebral compression fractures, has been seldom mentioned in the literature...
January 31, 2019: Osteoporosis International
https://read.qxmd.com/read/30702631/a-risk-scoring-model-to-predict-renal-progression-associated-with-postcontrast-acute-kidney-injury-in-chronic-kidney-disease-patients
#14
Seung Don Baek, So Mi Kim, Jae-Young Kang, Minkyu Han, Eun Kyoung Lee, Jai Won Chang
Postcontrast acute kidney injury (AKI) occurs more frequently in patients with lower estimated glomerular filtration rate. We hypothesized that postcontrast AKI in chronic kidney disease (CKD) patients with distinct risk factors might be associated with accelerated renal progression.We undertook this retrospective cohort study to develop and validate a risk scoring model for predicting renal progression. In a development dataset, 18,278 contrast-enhanced CT scans were performed in 9097 patients with CKD (estimated glomerular filtration rate [eGFR] < 60 mL/min/1...
February 2019: Medicine (Baltimore)
https://read.qxmd.com/read/30702437/use-of-the-cha2ds2-vasc-score-for-risk-stratification-of-hospital-admissions-among-patients-with-cardiovascular-diseases-receiving-a-fourth-generation-synchronous-telehealth-program-retrospective-cohort-study
#15
Jen-Kuang Lee, Chi-Sheng Hung, Ching-Chang Huang, Ying-Hsien Chen, Pao-Yu Chuang, Jiun-Yu Yu, Yi-Lwun Ho
BACKGROUND: Telehealth programs are generally diverse in approaching patients, from traditional telephone calling and texting message and to the latest fourth-generation synchronous program. The predefined outcomes are also different, including hypertension control, lipid lowering, cardiovascular outcomes, and mortality. In previous studies, the telehealth program showed both positive and negative results, providing mixed and confusing clinical outcomes. A comprehensive and integrated approach is needed to determine which patients benefit from the program in order to improve clinical outcomes...
January 31, 2019: Journal of Medical Internet Research
https://read.qxmd.com/read/30701873/gender-features-of-comorbidity-in-patients-with-coronary-artery-disease
#16
A N Sumin, E V Korok, A V Shcheglova, O L Barbarash
AIM: To study the factors associated with high levels of comorbidity in men and women with coronary artery disease (CAD). MATERIALS AND METHODS: The data analyzed 742 patients who were screened in the clinic of the research Institute CPSS in 2011, before planned operation coronary artery bypass grafting. All patients were divided into 2 groups: group I - men (n=595; 58 [54; 64] years), group II - women (n=147; 63 [57; 69] years). RESULTS: The analysis showed that the presence of arterial hypertension and atrial fibrillation prevailed in the group of women (p&lt;0...
April 19, 2018: Terapevticheskiĭ Arkhiv
https://read.qxmd.com/read/30701749/vitamin-d-deficiency-and-cardiovascular-pathology
#17
REVIEW
V I Podzolkov, A E Pokrovskaya, O I Panasenko
Vitamin D deficiency is widespread worldwide and present in about 30-50% of population. In most cases, this problem is associated with musculoskeletal system pathology: rickets in children, and osteomalacia or osteoporosis in adults. However, in recent years, convincing data was obtained on the links between vitamin D deficiency and cardiovascular pathology. Low Vitamin D levels in humans are associated with the unfavorable cardiovascular risk factors, such as arterial hypertension (AH), diabetes mellitus, and dyslipidemia, which are the predictors of the severe cardiovascular diseases, including strokes and infarctions...
September 20, 2018: Terapevticheskiĭ Arkhiv
https://read.qxmd.com/read/30701729/features-of-the-clinics-and-treatment-of-patients-with-obesity-and-hypertension-according-to-the-national-register-of-arterial-hypertension
#18
E V Oshchepkova, N V Lazareva, I E Chazova
AIM: The purpose of this study lied in the examination of the clinical characteristics and assessment of the quality of treatment for patients with arterial hypertension (AH) with obesity according to the National Registry of the AH. MATERIALS AND METHODS: The frequency of obesity in a sample of patients with AH, observed in 2010-2016. in polyclinics and cardiological dispensaries for cardiovascular diseases (CVD), was 38.3%, of which the incidence of severe obesity (grade III) was 8%...
September 20, 2018: Terapevticheskiĭ Arkhiv
https://read.qxmd.com/read/30701607/heart-failure-among-people-with-type-2-diabetes-mellitus-real-world-data-of-289-954-people-from-a-diabetes-database
#19
D Stoyanova, B Stratmann, A Schwandt, N Heise, S Mühldorfer, H-J Ziegelasch, A Zimmermann, D Tschoepe, R W Holl
AIM: Comparing people with Type 2 diabetes mellitus with and without heart failure in terms of metabolic control, therapeutic regimen and comorbidities. METHODS: The Prospective Diabetes Registry (DPV) is a longitudinal documentation system for demographics, medical care and outcome in people with diabetes mellitus. It consists of follow-up data from people with diabetes mellitus who have agreed to be recorded in the registry. Clinical data are submitted by general practitioners, specialists and clinics throughout Germany and Austria...
January 30, 2019: Diabetic Medicine: a Journal of the British Diabetic Association
https://read.qxmd.com/read/30700270/acute-kidney-injury-in-patients-with-myocardial-infarction-undergoing-percutaneous-coronary-intervention-using-radial-versus-femoral-access
#20
Vojko Kanic, Gregor Kompara, David Šuran, Alojz Tapajner, Franjo Husam Naji, Andreja Sinkovic
BACKGROUND: Data on radial access (RA) as an independent risk factor for acute kidney injury (AKI) in myocardial infarction (MI) patients are conflicting. Our aim was to assess how RA influences the incidence of AKI in MI patients undergoing percutaneous coronary intervention (PCI). METHODS: Data from 3842 MI patients undergoing PCI at our institution from January 2011 to December 2016, of which 35.8% were performed radially, were retrospectively analyzed. A propensity-matched analysis was performed to adjust for differences in the baseline characteristics between the RA and femoral access (FA) groups...
January 30, 2019: BMC Nephrology
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