keyword
https://read.qxmd.com/read/37377673/reliability-and-validity-of-the-electronic-version-of-the-hopkins-verbal-learning-test-revised-in-middle-aged-and-elderly-chinese-people
#21
JOURNAL ARTICLE
Lichen Jiang, Ming Xu, Shunyao Xia, Jiahui Zhu, Qi Zhou, Luoyi Xu, Chuan Shi, Daxing Wu
BACKGROUND: The aging population is increasing, making it essential to have a standardized, convenient, and valid electronic memory test that can be accessed online for older people and caregivers. The electronic version of the Hopkins Verbal Learning Test-Revised (HVLT-R) as a test with these advantages and its reliability and validity has not yet been tested. Thus, this study examined the reliability and validity of the electronic version of the HVLT-R in middle-aged and elderly Chinese people to provide a scientific basis for its future dissemination and use...
2023: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/37230430/dose-dependent-atrophy-in-bilateral-amygdalae-and-nuclei-after-brain-radiotherapy-association-with-mood-and-memory-outcomes-on-a-longitudinal-clinical-trial
#22
JOURNAL ARTICLE
Soumya Unnikrishnan, Roshan Karunamuni, Mia A Salans, Suma Gudipati, Alexander S Qian, Justin Yu, Michael Connor, Minh-Phuong Huynh-Le, Michelle D Tibbs, Gretchen Hermann, Anny Reyes, Alena Stasenko, Tyler M Seibert, Carrie McDonald, Jona A Hattangadi-Gluth
BACKGROUND: Amygdalae, bilateral almond-shaped structures located anterior to the hippocampi, are critical to limbic system functions of emotional processing and memory consolidation. The amygdalae are heterogeneous, composed of multiple nuclei with distinct structural and functional properties. We prospectively assessed associations between longitudinal changes in amygdala morphometry, including component nuclei, and functional outcomes in primary brain tumor patients receiving radiation therapy (RT)...
May 23, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37150264/sustained-preservation-of-cognition-and-prevention-of-patient-reported-symptoms-with-hippocampal-avoidance-during-whole-brain-radiation-therapy-for-brain-metastases-final-results-of-nrg-oncology-cc001
#23
JOURNAL ARTICLE
Vinai Gondi, Snehal Deshmukh, Paul D Brown, Jeffrey S Wefel, Terri S Armstrong, Wolfgang A Tome, Mark R Gilbert, Andre Konski, Clifford G Robinson, Joseph A Bovi, Tammie L S Benzinger, David Roberge, Vijayananda Kundapur, Isaac Kaufman, Sunjay Shah, Kenneth Y Usuki, Andrew M Baschnagel, Minesh P Mehta, Lisa A Kachnic
PURPOSE: Initial report of NRG Oncology CC001, a phase 3 trial of whole-brain radiation therapy plus memantine (WBRT + memantine) with or without hippocampal avoidance (HA), demonstrated neuroprotective effects of HA with a median follow-up of fewer than 8 months. Herein, we report the final results with complete cognition, patient-reported outcomes, and longer-term follow-up exceeding 1 year. METHODS AND MATERIALS: Adult patients with brain metastases were randomized to HA-WBRT + memantine or WBRT + memantine...
May 6, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37069570/berberine-improves-negative-symptoms-and-cognitive-function-in-patients-with-chronic-schizophrenia-via-anti-inflammatory-effect-a-randomized-clinical-trial
#24
JOURNAL ARTICLE
Zhengping Pu, Hui Wen, Hongxia Jiang, Qingmei Hou, Hui Yan
BACKGROUND: Based on the neuroinflammation hypothesis in schizophrenia and known anti-inflammatory effects of berberine, the aim of the present study is to investigate the efficacy of berberine in treating negative symptoms and cognitive deficits in adult patients with chronic schizophrenia. METHODS: Enrolled participants were randomized to receive berberine or placebo for 3 months. The Scale for the Assessment of Negative Symptoms (SANS), Trail-making Test A (TMT-A), Trail-making Test B (TMT-B), and Hopkins Verbal Learning Test (HVLT) were used to evaluate the negative symptoms and cognitive function at four-time points (baseline, 1st, 2nd, and 3rd month)...
April 17, 2023: Chinese Medicine
https://read.qxmd.com/read/37033023/the-alternate-form-reliability-study-of-six-variants-of-the-brief-visual-spatial-memory-test-revised-and-the-hopkins-verbal-learning-test-revised
#25
JOURNAL ARTICLE
Yumei Cai, Tianlong Yang, Xin Yu, Xue Han, Gong Chen, Chuan Shi
INTRODUCTION: The revised Hopkins Verbal Learning Test-Revised (HVLT-R) and the Brief Visual-Spatial Memory Test-Revised (BVMT-R) are two widely used test involving verbal and visual learning and memory. In the two tests, six different versions are assembled, respectively, to prevent learning effects. Currently, no researchers have compared the six versions of the two tests. Thus, their usefulness in clinical studies requiring multiple follow-ups is limited. In this work, we confirm the equivalence of six HVLT-R and BVMT-R versions...
2023: Frontiers in Public Health
https://read.qxmd.com/read/37006704/verbal-and-visual-learning-ability-in-patients-with-treatment-resistant-schizophrenia-a-1-year-follow-up-study
#26
JOURNAL ARTICLE
Urska Arnautovska, Kathryn Vitangcol, James P Kesby, Nicola Warren, Susan L Rossell, Erica Neill, Anthony Harris, Cherrie Galletly, David Castle, Dan Siskind
OBJECTIVE: In the general population, repeated cognitive testing produces learning effects with potential for improved test performance. It is currently unclear whether the same effect of repeated cognitive testing on cognition pertains to people living with schizophrenia, a condition often associated with significant cognitive impairments. This study aims to evaluate learning ability in people with schizophrenia and-considering the evidence that antipsychotic medication can additionally impair cognitive performance-explore the potential impact of anticholinergic burden on verbal and visual learning...
September 2023: Schizophrenia Research. Cognition
https://read.qxmd.com/read/36786939/verbal-memory-performance-and-depressive-symptoms-in-persons-with-treated-hiv
#27
JOURNAL ARTICLE
Lujie Xu, M John Gill, Christopher Power, Esther Fujiwara
The link between memory and comorbid depression in persons with HIV (PWH) is unclear based on evidence from published cohorts. We compared verbal memory in the HVLT-R in a well-characterized HIV cohort (n = 354) with (n = 102) or without (n = 252) comorbid depressive symptoms, and examined memory correlates in both scenarios. Memory fell within unimpaired ranges, but was lower in depressed than non-depressed PWH. Memory was related to quality of life, sociodemographic, and mental health factors, but not to assessed HIV-related or antiretroviral factors...
February 14, 2023: AIDS and Behavior
https://read.qxmd.com/read/36705542/intraindividual-change-in-cognitive-function-among-adults-with-systemic-lupus-erythematosus-a-markov-analysis-over-7%C3%A2-years
#28
JOURNAL ARTICLE
Stefan Perera, Richard Cook, Ker-Ai Lee, Patti Katz, Zahi Touma
OBJECTIVE: Cognitive impairment is prevalent in systemic lupus erythematosus (SLE). There remain gaps in understanding cognition and SLE longitudinally. We studied intraindividual change in cognition in SLE over time. METHODS: Data were from the University of California, San Francisco Lupus Outcome Study, which included 1281 adults with SLE. The Hopkins Verbal Learning Test-Revised (HVLT-R) and the Controlled Oral Word Association Test (COWAT) were administered annually over 7 years...
March 2023: ACR open rheumatology
https://read.qxmd.com/read/36578297/short-chain-fatty-acids-in-patients-with-schizophrenia-and-ultra-high-risk-population
#29
JOURNAL ARTICLE
Huiqing Peng, Lijun Ouyang, David Li, Zongchang Li, Liu Yuan, Lejia Fan, Aijun Liao, Jinguang Li, Yisen Wei, Zihao Yang, Xiaoqian Ma, Xiaogang Chen, Ying He
BACKGROUND: Individuals who experience the prodromal phase of schizophrenia (SCZ), a common and complex psychiatric disorder, are referred to as ultra-high-risk (UHR) individuals. Short-chain fatty acid (SCFA) is imperative in the microbiota-gut-brain axis and brain function. Accumulating amount of evidence shows the connections between psychiatric disorders and SCFAs. This study aims to explore the underlying roles SCFAs play in SCZ by investigating the association of alterations in SCFAs concentrations with common cognitive functions in both the SCZ and UHR populations...
2022: Frontiers in Psychiatry
https://read.qxmd.com/read/36565574/effect-of-physical-exercise-on-the-hippocampus-and-global-grey-matter-volume-in-breast-cancer-patients-a-randomized-controlled-trial-pam-study
#30
JOURNAL ARTICLE
E W Koevoets, M I Geerlings, E M Monninkhof, R Mandl, L Witlox, E van der Wall, M M Stuiver, G S Sonke, M J Velthuis, J J Jobsen, J van der Palen, M E M M Bos, E Göker, M B E Menke-Pluijmers, D W Sommeijer, A M May, M B de Ruiter, S B Schagen
BACKGROUND: Physical exercise in cancer patients is a promising intervention to improve cognition and increase brain volume, including hippocampal volume. We investigated whether a 6-month exercise intervention primarily impacts total hippocampal volume and additionally hippocampal subfield volumes, cortical thickness and grey matter volume in previously physically inactive breast cancer patients. Furthermore, we evaluated associations with verbal memory. METHODS: Chemotherapy-exposed breast cancer patients (stage I-III, 2-4 years post diagnosis) with cognitive problems were included and randomized in an exercise intervention (n = 70, age = 52...
December 14, 2022: NeuroImage: Clinical
https://read.qxmd.com/read/36510855/concurrent-validity-and-reliability-of-at-home-teleneuropsychological-evaluations-among-people-with-and-without-hiv
#31
JOURNAL ARTICLE
Maulika Kohli, Arin Fisher, Ni Sun-Suslow, Anne Heaton, Matthew S Dawson, Jennifer Marquie, Donald R Franklin, Maria Marquine, Jennifer E Iudicello, Robert K Heaton, David J Moore
OBJECTIVE: To determine the reliability of teleneuropsychological (TNP) compared to in-person assessments (IPA) in people with HIV (PWH) and without HIV (HIV-). METHODS: Participants included 80 PWH (Mage = 58.7, SDage = 11.0) and 23 HIV- (Mage = 61.9, SDage = 16.7). Participants completed two comprehensive neuropsychological IPA before one TNP during the COVID-19 pandemic (March-December 2020). The neuropsychological tests included: Hopkins Verbal Learning Test-Revised (HVLT-R Total and Delayed Recall), Controlled Oral Word Association Test (COWAT; FAS-English or PMR-Spanish), Animal Fluency, Action (Verb) Fluency, Wechsler Adult Intelligence Scale 3rd Edition (WAIS-III) Symbol Search and Letter Number Sequencing, Stroop Color and Word Test, Paced Auditory Serial Addition Test (Channel 1), and Boston Naming Test...
December 13, 2022: Journal of the International Neuropsychological Society: JINS
https://read.qxmd.com/read/36477709/the-effects-of-transcutaneous-vagus-nerve-stimulation-on-functional-connectivity-within-semantic-and-hippocampal-networks-in-mild-cognitive-impairment
#32
JOURNAL ARTICLE
Aidan J Murphy, Alexandria G O'Neal, Ronald A Cohen, Damon G Lamb, Eric C Porges, Sarah A Bottari, Brian Ho, Erin Trifilio, Steven T DeKosky, Kenneth M Heilman, John B Williamson
Better treatments are needed to improve cognition and brain health in people with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Transcutaneous vagus nerve stimulation (tVNS) may impact brain networks relevant to AD through multiple mechanisms including, but not limited to, projection to the locus coeruleus, the brain's primary source of norepinephrine, and reduction in inflammation. Neuropathological data suggest that the locus coeruleus may be an early site of tau pathology in AD. Thus, tVNS may modify the activity of networks that are impaired and progressively deteriorate in patients with MCI and AD...
December 7, 2022: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://read.qxmd.com/read/36420209/association-of-pretreatment-hippocampal-volume-with-neurocognitive-function-in-patients-treated-with-hippocampal-avoidance-whole-brain-radiation-therapy-for-brain-metastases-secondary-analysis-of-nrg-oncology-rtog-0933
#33
JOURNAL ARTICLE
Christopher D Abraham, Stephanie L Pugh, Joseph A Bovi, Vinai Gondi, Minesh P Mehta, Tammie Benzinger, Christopher J Owen, Simon S Lo, Vijayananda Kundapur, Paul D Brown, Alexander Y Sun, Steven P Howard, Albert S DeNittis, Clifford G Robinson, Lisa A Kachnic
PURPOSE: Hippocampal volume (HV) is an established predicting factor for neurocognitive function (NCF) in neurodegenerative disease. Whether the same phenomenon exists with hippocampal-avoidant whole brain radiation therapy is not known; therefore, we assessed the association of baseline HV with NCF among patients enrolled on RTOG 0933. METHODS AND MATERIALS: Hippocampal volume and total brain volume were calculated from the radiation therapy plan. Hippocampal volume was correlated with baseline and 4-month NCF scores (Hopkins Verbal Learning Test-Revised [HVLT-R] Total Recall [TR], Immediate Recognition, and Delayed Recall [DR]) using Pearson correlation...
2022: Advances in Radiation Oncology
https://read.qxmd.com/read/36341847/a-randomized-controlled-trial-to-test-the-efficacy-of-a-diabetes-behavioral-intervention-to-prevent-memory-decline-in-older-blacks-african-americans-with-diabetes-and-mild-cognitive-impairment
#34
JOURNAL ARTICLE
Robin Casten, Benjamin E Leiby, Megan Kelley, Barry W Rovner
BACKGROUND: The prevalence of dementia in Blacks/African Americans (AAs) is almost twice that of Whites. Inequities in access to health care, socioeconomic conditions, and diabetes contribute to this disparity. Poorly controlled diabetes, which is more prevalent in Blacks/AAs, causes microvascular disease and neurodegeneration and increases dementia risk. Improving glycemic control, therefore, may prevent cognitive decline. To address this issue, we developed Diabetes Regulation for Eyesight and Memory (DREAM), a community health worker (CHW)-led behavioral intervention to improve diabetes self-management and thereby prevent cognitive decline...
October 28, 2022: Contemporary Clinical Trials
https://read.qxmd.com/read/36124711/sensorimotor-and-frontoparietal-network-connectivity-are-associated-with-subsequent-maintenance-of-gait-speed-and-episodic-memory-in-older-adults
#35
JOURNAL ARTICLE
Chun Liang Hsu, Brad Manor, Thomas Travison, Alvaro Pascual-Leone, Lewis A Lipsitz
BACKGROUND: Slow gait is predictive of functional impairments in older adults, while concomitant slow gait and cognitive complaints are associated with greater risk for cognitive decline and dementia. However, functional neural correlates for gait speed maintenance are unclear. As the sensorimotor network (SMN) and frontoparietal network (FPN) are integral components of these functions, this study investigated differences in SMN and FPN in older adults with/without gait speed decline over 24 months; and whether these networks were associated with maintenance of cognitive function...
September 17, 2022: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://read.qxmd.com/read/36107958/learning-and-memory-function-in-young-people-with-and-without-perinatal-hiv-in-england
#36
JOURNAL ARTICLE
Alejandro Arenas-Pinto, Ali Judd, Diane Melvin, Marthe Le Prevost, Caroline Foster, Kate Sturgeon, Alan Winston, Lindsay C Thompson, Diana M Gibb, Hannah Castro
Learning and memory are important for successful education and career progression. We assess these functions in young people (YP) with perinatal HIV (PHIV) (with or without a previous AIDS-defining illness) and a comparable group of HIV-negative YP. 234 PHIV and 68 HIV-negative YP completed 9 tests; 5 National Institutes of Health (NIH) Toolbox tests (2 executive function, 1 speed of information processing, 2 memory); 2 Hopkins Verbal Learning Test Revised (HVLT-R) (learning (L), delayed recall (R)), and 2 verbal application measures...
2022: PloS One
https://read.qxmd.com/read/35992609/green-tea-improves-cognitive-function-through-reducing-ad-pathology-and-improving-anti-oxidative-stress-capacity-in-chinese-middle-aged-and-elderly-people
#37
JOURNAL ARTICLE
Ran Zhang, Lei Zhang, Zeng Li, Ping Zhang, Hao Song, Dong-Ai Yao, Jing Cao, Jun-Jian Zhang
Background: Numerous benefits of green tea have been reported. However, the effects of green tea on cognitive function remain disputable and the mechanism is still unclear. Objective: To investigate the relationship of green tea consumption with cognitive function and related blood biomarkers among Chinese middle-aged and elderly people. Methods: A total of 264 participants aged 50-70 years old were enrolled from Zhongnan Hospital of Wuhan University. They were interviewed about green tea consumption patterns and underwent neuropsychological tests covering five main cognitive domains to assess cognition including Montreal Cognitive Assessment (MoCA) and the other 10 scales...
2022: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/35855458/corticosteroids-use-and-neurocognitive-functioning-in-patients-with-recurrent-glioblastoma-evidence-from-european-organization-for-research-and-treatment-of-cancer-eortc-trial-26101
#38
JOURNAL ARTICLE
Ivan Caramanna, Julie M de Kort, Alba A Brandes, Walter Taal, Michael Platten, Ahmed Idbaih, Jean Sebastien Frenel, Wolfgang Wick, Chandrakanth Jayachandran Preetha, Martin Bendszus, Philipp Vollmuth, Jaap C Reijneveld, Martin Klein
Background: In patients with recurrent glioblastoma, corticosteroids are frequently used to mitigate intracranial pressure and to improve patient neurological functioning. To date, in these patients, no systematic studies have been performed to assess neurocognitive functioning (NCF) in relation to corticosteroid treatment. Methods: Using baseline data (ie, prior to randomization) of European Organization for Research and Treatment of Cancer (EORTC) trial 26101, we performed regression analysis to assess the predictive value of corticosteroid intake on performance of the EORTC brain tumor clinical trial NCF test battery...
August 2022: Neuro-oncology Practice
https://read.qxmd.com/read/35786160/impaired-verbal-memory-in-individuals-living-with-hiv-and-cocaine-dependence
#39
JOURNAL ARTICLE
Sarah E Nigro, Minjie Wu, Anthony C Juliano, T Celeste Napier, Alan L Landay, Audrey L French, Shaolin Yang
INTRODUCTION: Our study aimed to understand the independent and combined effects of cocaine dependence and HIV status across aspects of verbal memory. METHOD: Our sample consisted of a total of 102 individuals: 28 individuals living with HIV and cocaine dependence (HIV+/CD), 28 individuals who are HIV-negative with cocaine dependence (HIV-/CD), 20 individuals living with HIV without cocaine dependence (HIV+/ND), and 26 individuals who are HIV-negative without cocaine dependence (HIV-/ND)...
July 4, 2022: Journal of Clinical and Experimental Neuropsychology
https://read.qxmd.com/read/35693343/distinct-effects-of-the-apolipoprotein-e-%C3%AE%C2%B54-genotype-on-associations-between-delayed-recall-performance-and-resting-state-electroencephalography-theta-power-in-elderly-people-without-dementia
#40
JOURNAL ARTICLE
Jing Wang, Tingting Sun, Ying Zhang, Xin Yu, Huali Wang
Background: Abnormal electroencephalography (EEG) activity has been demonstrated in mild cognitive impairment (MCI), and theta rhythm might be inversely related to memory. The apolipoprotein E (ApoE) epsilon 4 (ε4) allele, as a genetic vulnerability factor for pathologic and normal age-related cognitive decline, may influence different patterns of cognitive dysfunction. Therefore, the present study primarily aimed to verify the role of resting theta rhythm in delayed recall deficits, and further explore the effects of the ApoE genotype on the associations between the resting theta power and delayed recall performance in the elderly individuals without dementia...
2022: Frontiers in Aging Neuroscience
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