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Head And Neck Brachytherapy

Bas Vaarwerk, Marinka L F Hol, Reineke A Schoot, Willemijn B Breunis, Maartje M L de Win, Henrike Westerveld, Raquel Davila Fajardo, Peerooz Saeed, Michiel W van den Brekel, Bradley R Pieters, Simon D Strackee, Ludi E Smeele, Johannes H M Merks
BACKGROUND AND PURPOSE: Survival after relapse of head and neck rhabdomyosarcoma (HNRMS) after prior external beam radiotherapy (EBRT) is poor, since options for adequate local treatment are often lacking. In this study we describe our experience with salvage AMORE in patients with relapsed HNRMS after prior EBRT. MATERIALS AND METHODS: Patients with relapsed HNRMS after prior EBRT in which salvage AMORE treatment was considered feasible were analysed; this includes patients with parameningeal, head and neck non-parameningeal and orbital localization...
February 2019: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
John Leung, Margot Lehman
INTRODUCTION: This paper reports the key findings of the first survey of Australian, New Zealand (ANZ) and Singaporean radiation oncology trainees on contouring and planning. METHODS: The survey was conducted from May to July 2018 using a 35-question instrument. It was emailed to all ANZ and Singaporean trainees on the Royal Australian and New Zealand College of Radiologists (RANZCR) database with at least 6 months experience. The questions related to demographics, time spent on contouring, most difficult sites to contour, most useful atlas, feedback on contouring, interaction with radiation therapists, plan reviews, stereotactic radiation therapy (SBRT), brachytherapy and suggested areas of improvement...
February 5, 2019: Journal of Medical Imaging and Radiation Oncology
Francesco Bussu, Luca Tagliaferri, Giancarlo Mattiucci, Claudio Parrilla, Davide Rizzo, Maria Antonietta Gambacorta, Valentina Lancellotta, Rosa Autorino, Carla Fonnesu, Caterina Kihlgren, Jacopo Galli, Gaetano Paludetti, György Kovács, Vincenzo Valentini
BACKGROUND: Interventional radiotherapy (brachytherapy; IRT) reemerged in the last decades as a potentially useful tool in head and neck oncology after a set of clear technical improvements were developed. METHODS: Sixty-one high dose ratio (HDR) IRT treatments were recommended and performed on 58 patients. We classified the cases into four relatively homogeneous groups based on the clinical needs that led to the recommended IRT. Also, we separately evaluated primary and recurrent cases...
January 30, 2019: Head & Neck
Guo-Hao Zhang, Xiao-Ming Lv, Wen-Jie Wu, Zhi-Yuan Wu, Lei Zheng, Ming-Wei Huang, Yong Wang, Jian-Guo Zhang
PURPOSE: We sought to investigate the feasibility and accuracy of computer-assisted techniques in the interstitial brachytherapy of the deep regions of the head and neck. MATERIALS AND METHODS: A computer-assisted brachytherapy workflow was applied to 10 patients with tumors in the deep regions of the head and neck. Based on the brachytherapy treatment preplan, we constructed a digital stereotactic model to accurately transfer the virtual plan into the navigation system, and subsequently printed the individual templates...
January 9, 2019: Brachytherapy
Y L Jiang, Z Ji, S Q Tian, F X Guo, H S Yuan, C Liu, H T Sun, J J Wang
Objective: To investigate the efficacy of CT-guidance interstitial Iodine-125 seed brachytherapy as a salvage therapy for recurrent head and neck carcinoma. Methods: A total of 122 patients who had been treated for recurrent head and neck carcinoma with CT-guided Iodine-125 seed permanent implantation were conducted a retrospective analysis at Peking University Third Hospital from February 2003 to December 2015. The study included 78 male and 44 female patients. Of the 122 patients, 76 had undergone radical surgery, 106 had received EBRT...
December 4, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Julianna Rodin, Voichita Bar-Ad, David Cognetti, Joseph Curry, Jennifer Johnson, Chad Zender, Laura Doyle, David Kutler, Benjamin Leiby, William Keane, Adam Luginbuhl
Purpose: To review brachytherapy use in recurrent head and neck carcinoma (RHNC) with focus on its efficacy and complication rates. Material and methods: A literature search of PubMed, Ovid, Google Scholar, and Scopus was conducted from 1990 to 2017. Publications describing treatment of RHNC with brachytherapy with or without surgery were included. The focus of this review is on oncologic outcomes and the safety of brachytherapy in the recurrent setting. Results: Thirty studies involving RHNC treatment with brachytherapy were reviewed...
October 2018: Journal of Contemporary Brachytherapy
Rajendra Bhalavat, Vibhay Pareek, Manish Chandra, Lalitha Nellore, Karishma George, Dipalee Borade, Ketan Kalariya, Zaiba Moosa, Amrita Srivastava, Navaneeth Reddy, Ankita Kapoor, Darshana Kawale, Nandakumar P, Pratibha Bauskar
Purpose: High-dose-rate (HDR) interstitial brachytherapy has an established role in head and neck malignancies and offers good survival rates; however, there is scant data on improved local control (LC) and treatment-related complications in recurrent cases. We present our results in patients with recurrent head and neck cancers treated with HDR interstitial brachytherapy. Material and methods: Twenty-five patients with recurrent head and neck cancers were treated with HDR interstitial brachytherapy using Iridium 192 between 2009 and 2016...
October 2018: Journal of Contemporary Brachytherapy
Trevor J Royce, Kathy Dwyer, C Winnie Yu-Moe, Courtney DeRoo, Joseph O Jacobson, Roy B Tishler
BACKGROUND: Medical errors in radiation oncology (RO) practice have received significant national attention over the last decade. Medical errors can lead to malpractice cases. Better characterizing these events can educate providers with the goal of improving patient care. METHODS: The REMOVED FOR BLINDING Comparative Benchmarking System (CBS) represents approximately 30% of all closed US malpractice cases and includes the experience of over 30 academic hospitals...
November 12, 2018: International Journal of Radiation Oncology, Biology, Physics
Wei-Ping Jie, Jia-Ying Bai, Bin-Bin Li
Oral squamous cell carcinoma is a common malignancy in the head and neck region. Brachytherapy after radical surgery has achieved much progress as a cancer adjuvant treatment. This study focused on the pathologic characteristics of the patients with oral squamous cell carcinoma who underwent seed implantation after radical surgery, and the relationship of these characteristics with prognosis. Thus, 76 patients with oral squamous cell carcinoma, who were treated with surgery and subsequently with iodine 125 (125 I) radioactive seed implantation, were recruited in this study...
January 1, 2018: Technology in Cancer Research & Treatment
Luca Tagliaferri, Ashwini Budrukkar, Jacopo Lenkowicz, Mauricio Cambeiro, Francesco Bussu, Jose Luis Guinot, Guido Hildebrandt, Bengt Johansson, Jens E Meyer, Peter Niehoff, Angeles Rovirosa, Zoltán Takácsi-Nagy, Luca Boldrini, Nicola Dinapoli, Vito Lanzotti, Andrea Damiani, Roberto Gatta, Bruno Fionda, Valentina Lancellotta, Tamer Soror, Rafael Martìnez Monge, Vincenzo Valentini, György Kovács
Purpose: Clinical data collecting is expensive in terms of time and human resources. Data can be collected in different ways; therefore, performing multicentric research based on previously stored data is often difficult. The primary objective of the ENT COBRA (COnsortium for BRachytherapy data Analysis) ontology is to define a specific terminological system to standardized data collection for head and neck (H&N) cancer patients treated with interventional radiotherapy. Material and methods: ENT-COBRA is a consortium for standardized data collection for H&N patients treated with interventional radiotherapy...
June 2018: Journal of Contemporary Brachytherapy
Corinna Melchert, Tamer Soror, György Kovács
Purpose: Brachytherapy procedure may result in acute tissue reactions like edema, causing deviations between planned and measured doses. The rationale for in vivo dosimetry in interstitial brachytherapy is to assess the accuracy of the delivered dose in comparison with the dose calculated by the treatment planning system (TPS). Material and methods: One single computer tomography (CT) dataset was used for brachytherapy planning, taken within 24 hours after implantation...
June 2018: Journal of Contemporary Brachytherapy
Suruchi Ambasta, Satyen Parida, Priya Rudingwa, Sandeep Kumar Mishra
No abstract text is available yet for this article.
June 2018: Indian Journal of Anaesthesia
William Breen, Jacqueline Kelly, Henry S Park, Yung Son, Clarence Sasaki, Lynn Wilson, Roy Decker, Zain A Husain
OBJECTIVE: To evaluate our institutional experience using brachytherapy for the re-irradiation of the head and neck. STUDY DESIGN/METHODS: We reviewed the records of patients who received brachytherapy for head and neck cancer in a previously irradiated field between 2007 and 2016. RESULTS: Sixty-nine patients received brachytherapy-based re-irradiation. Forty-nine patients (71%) were treated for recurrent cancers, 15 patients (22%) had second primary cancers, and five patients (7%) were treated for persistent tumors...
April 22, 2018: Curēus
Trevor J Royce, Muhammad M Qureshi, Minh Tam Truong
BACKGROUND: The changing use of radiation as a first-line cancer therapy in the United States is poorly characterized. This study aims to report radiotherapy utilization and fractionation patterns during the first course of cancer treatment. METHODS: We extracted all solid tumor cases from 2004 to 2014 in the National Cancer Data Base, which captures only the first course of treatment. Patients were subcategorized by disease site: breast, central nervous system (CNS), gastrointestinal, genitourinary, gynecologic, head and neck (HN), musculoskeletal, skin, or thoracic...
June 11, 2018: Journal of the American College of Radiology: JACR
A S Kirthi Koushik, Ram Charith Alva
We performed an e-Survey and reviewed the literature on the prevalence of use of brachytherapy in head and neck cancers in order to understand the patterns of care and probable application of this modality. A five-point questionnaire was prepared and sent to 300 oncologists through a web-based survey engine. This was done in preparation for my lecture on "Ongoing Research and Potential Research Avenues" in IBSCON held in Chennai in August 2016. SPSS software was used for the statistical analysis. Of a total of 300 emails that were sent out for the survey, 120 replies were received, which is 40%...
June 2018: Indian Journal of Surgical Oncology
M Quivrin, K Peignaux-Casasnovas, É Martin, M Rouffiac, D Thibouw, C Chevalier, N Vulquin, L Aubignac, G Truc, G Créhange
The treatment of local recurrence of a previously irradiated cancer or a second cancer arising in-field remains challenging. Ultimately, the objective of salvage therapy is to control disease while ensuring minimal collateral damage, thereby optimizing both cancer and toxicity outcomes. Reirradiation has historically been associated with unacceptable toxicity and a limited benefit. Brachytherapy offers the best dose distribution and a high radiation dose to the target volume while better protecting surrounding previously irradiated healthy tissues...
June 2018: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
D Peiffert, B Coche-Dequéant, M Lapeyre, S Renard
The main indications of the brachytherapy of head and neck cancers are the limited tumours of the lip, the nose, the oral cavity and the oropharynx. Nasopharynx tumours are nowadays treated by intensity-modulated radiotherapy. This technique can be exclusive, associated with external radiotherapy or postoperative. It can also be a salvage treatment for the second primaries in previously irradiated areas. If the low dose rate brachytherapy rules remain the reference, the pulse dose rate technique allows the prescription of the dose rate and the optimisation of the dose distribution...
June 2018: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
Bita Kalaghchi, Ebrahim Esmati, Reza Ghalehtaki, Marzieh Gomar, Ramin Jaberi, Soraya Gholami, Somayyeh Babaloui, Mansoureh Nabavi, Sarvazad Sotoudeh, Nezhat Khanjani, Ali Kazemian, Farnaz Amouzegar-Hashemi, Mahdi Aghili, Marzieh Lashkari
Purpose: Skin cancers are the most common human malignancy with increasing incidence. Currently, surgery is standard of care treatment for non-melanoma skin cancers. However, brachytherapy is a growing modality in the management of skin cancers. Therefore, we aimed to assess the outcome of patients with non-melanoma skin cancers treated by high-dose-rate (HDR) brachytherapy with surface mold technique. Material and methods: In this prospective study, we recruited patients with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) of the skin who were candidates for definitive or adjuvant brachytherapy during 2013-2014...
April 2018: Journal of Contemporary Brachytherapy
Siddhartha Laskar, Avinash Pilar, Nehal Khanna, Ajay Puri, Ashish Gulia, Sajid Qureshi, Girish Chinnaswamy, Tushar Vora, Mukta Ramadwar
PURPOSE: Evaluate long-term clinical outcomes, adverse effects, and evolving practice of interstitial brachytherapy (BT) for pediatric soft tissue sarcomas (STS). METHODS: From September 1984 to December 2014, 105 children (median age 10 years) were included. There were 60 males and 45 females. The majority (74%) had primary lesions. Synovial sarcoma (22%) was the most frequent histology. Treatment included wide local excision and BT with or without external beam radiotherapy (EBRT)...
September 2018: Pediatric Blood & Cancer
Helena Doležalová, Nicole Blechová, Jiří Petera
BACKGROUND: The prevalence of head and neck tumors has continually increased over the past decades, which is a serious medical and social problem. This study retrospectively assessed the quality of life of patients with early-stage oral cavity tumors after high-dose rate (HDR) brachytherapy. MATERIAL AND METHODS: Quality of life was evaluated in 14 patients with early-onset oral cavity tumors who underwent HDR brachytherapy at the Department of Oncology and Radiotherapy, University Hospital Hradec Kralove...
2018: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
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