keyword
https://read.qxmd.com/read/38536762/the-impact-of-musculoskeletal-ill-health-on-quality-of-life-and-function-after-critical-care-a-multicentre-prospective-cohort-study
#1
JOURNAL ARTICLE
O D Gustafson, E B King, M M Schlussel, A Arnold, C Wade, P S Nicol, M J Rowland, H Dawes, M A Williams
Physical disability is a common component of post-intensive care syndrome, but the importance of musculoskeletal health in this population is currently unknown. We aimed to determine the musculoskeletal health state of intensive care unit survivors and assess its relationship with health-related quality of life; employment; and psychological and physical function. We conducted a multicentre prospective cohort study of adults admitted to intensive care for > 48 h without musculoskeletal trauma or neurological insult...
March 27, 2024: Anaesthesia
https://read.qxmd.com/read/38536534/serial-daily-lactate-levels-association-with-30-day-outcome-in-cardiogenic-shock-patients-treated-with-va-ecmo-a-post-hoc-analysis-of-the-hypo-ecmo-study
#2
JOURNAL ARTICLE
Bruno Levy, Nicolas Girerd, Guillaume Baudry, Kevin Duarte, Samuel Cuau, Jan Bakker, Antoine Kimmoun
BACKGROUND: Reliable predictors of outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy are limited. While elevated lactate levels over time have been linked to outcomes in cardiogenic shock (CS), their significance in VA-ECMO-treated patients remains inconclusive. METHODS: We conducted a post hoc analysis of data from the HYPO-ECMO trial, which compared normothermia to moderate hypothermia in CS patients supported by VA-ECMO. We examined daily lactate levels collected over a week to assess their correlation with 30-day mortality...
March 27, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38535052/automatic-active-lesion-tracking-in-multiple-sclerosis-using-unsupervised-machine-learning
#3
JOURNAL ARTICLE
Jason Uwaeze, Ponnada A Narayana, Arash Kamali, Vladimir Braverman, Michael A Jacobs, Alireza Akhbardeh
BACKGROUND: Identifying active lesions in magnetic resonance imaging (MRI) is crucial for the diagnosis and treatment planning of multiple sclerosis (MS). Active lesions on MRI are identified following the administration of Gadolinium-based contrast agents (GBCAs). However, recent studies have reported that repeated administration of GBCA results in the accumulation of Gd in tissues. In addition, GBCA administration increases health care costs. Thus, reducing or eliminating GBCA administration for active lesion detection is important for improved patient safety and reduced healthcare costs...
March 16, 2024: Diagnostics
https://read.qxmd.com/read/38533418/association-between-spo-2-and-the-risk-of-death-in-elderly-t2dm-patients-with-cerebral-infarction-a-retrospective-cohort-study
#4
JOURNAL ARTICLE
Shuo Zhang, Jiaqi Ji, Siqi Gao, Shu Yang, Zeyi Song, Jianmin Li, Junjie Liu
OBJECTIVE: This study aimed to evaluate the SpO2 (transcutaneous oxygen saturation) -mortality link in elderly T2DM (diabetes mellitus type 2) patients with cerebral infarction and identify their optimal SpO2 range. METHODS: In this investigation, we employed a comprehensive approach. Initially, we screened the MIMIC-IV database, identifying elderly T2DM patients with cerebral infarction, utilizing specific ICD-9 and ICD-10 codes. We then harnessed the power of restricted cubic splines to craft a visual representation of the correlation between SpO2 and 1-year mortality...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38533144/successful-fluid-management-in-respiratory-failure-due-to-clazosentan-following-a-cerebral-aneurysm-clipping-a-case-report
#5
Hirotaka Kinoshita, Kodai Kato, Yuma Yamazaki, Eiji Hashiba, Kazuyoshi Hirota
Clazosentan, a potent selective endothelin receptor subtype A antagonist, has been demonstrated to be effective in preventing cerebral vasospasms after subarachnoid hemorrhage. We report the successful management of respiratory failure due to pulmonary edema associated with clazosentan, with a hemodynamic monitoring system. A 49-year-old Japanese man underwent emergency clipping for a right internal carotid-posterior communicating artery aneurysm. The surgery and general anesthesia for the rupture proceeded with no complications...
February 2024: Curēus
https://read.qxmd.com/read/38532741/post-covid-syndrome-and-work-ability-9-12-months-after-a-sars-cov-2-infection-among-over-9000-employees-from-the-general-population
#6
JOURNAL ARTICLE
Stefanie Braig, Raphael S Peter, Alexandra Nieters, Hans-Georg Kräusslich, Stefan O Brockmann, Siri Göpel, Gerhard Kindle, Uta Merle, Jürgen M Steinacker, Winfried V Kern, Dietrich Rothenbacher
OBJECTIVES: Evidence on the work-related societal impact of long-term health-related consequences following SARS-CoV-2 is emerging. We characterize the modified work ability index (mWAI) of employees 6 to 12 months after an acute infection compared to pre-infection. METHODS: Analyses were based on a population-based, multi-center cross-sectional study including employees aged 18-65 years with positive SARS-CoV-2 polymerase chain reaction (tested between October 2020-April 2021 in defined geographic regions in Germany)...
March 2024: IJID Reg
https://read.qxmd.com/read/38532680/-experience-of-providing-intensive-rehabilitation-care-to-a-school-aged-child-with-living-donor-lobar-lung-transplantation
#7
JOURNAL ARTICLE
Chiao-Ting Tsai, Fang-Yi Lin
The post-operative intensive care experience of a school-aged child who received living-donor bilateral lobar lung transplantation due to acute respiratory distress syndrome and interstitial pulmonary fibrosis is discussed in this paper. The patient received lungs donated by her parents in a "living-donor bilateral lobar lung transplantation" due to severe lung function impairment. The patient felt anxious due to her long-term hospitalization for preoperative evaluation, various invasive treatments, and postoperative rehabilitation...
April 2024: Hu Li za Zhi the Journal of Nursing
https://read.qxmd.com/read/38532144/impact-of-a-multicomponent-exercise-training-program-on-muscle-strength-after-bariatric-surgery-a-randomized-controlled-trial
#8
JOURNAL ARTICLE
Giorjines Boppre, Florêncio Diniz-Sousa, Lucas Veras, Andrea Bezerra, Vitor Devezas, John Preto, Hugo Santos-Sousa, José Oliveira, Hélder Fonseca
PURPOSE: This study examined the benefits of an 11-months multicomponent exercise program (MEP) on muscular strength (MS) after bariatric surgery. METHODS: Of the 84 randomized patients, 41 participants from the exercise group (EG) and 20 participants from the control group (CG) were included in the analysis. The EG received supervised MEP for 11 months, starting 1-month post-bariatric surgery (BS) in addition to standard medical care, while the CG received medical care recommendations only...
March 27, 2024: Obesity Surgery
https://read.qxmd.com/read/38531709/palliative-care-in-the-cardiovascular-intensive-care-unit-a-systematic-review-of-current-literature
#9
REVIEW
Agastya D Belur, Aryan Mehta, Mridul Bansal, Patrick M Wieruszewski, Rachna Kataria, Marwan Saad, Annaliese Clancy, Daniel J Levine, Neel R Sodha, Douglas M Burtt, Gregory S Rachu, J Dawn Abbott, Saraschandra Vallabhajosyula
BACKGROUND: There has been an evolution in the disease severity and complexity of patients presenting to the cardiac intensive care unit (CICU). There are limited data evaluating the role of palliative care in contemporary CICU practice. METHODS: PubMed Central, CINAHL, EMBASE, Medline, Cochrane Library, Scopus, and Web of Science databases were evaluated for studies on palliative care in adults (≥18 years) admitted with acute cardiovascular conditions - acute myocardial infarction, cardiogenic shock, cardiac arrest, advanced heart failure, post-cardiac surgery, spontaneous coronary artery dissection, Takotsubo cardiomyopathy, and pulmonary embolism - admitted to the CICU, coronary care unit or cardiovascular intensive care unit from 1/1/2000 to 8/8/2022...
March 24, 2024: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/38531618/high-sensitive-troponint-interleukin-8-and-interleukin-6-link-with-post-surgery-risk-in-infant-heart-surgery
#10
JOURNAL ARTICLE
Elin M Thorlacius, Juho Keski-Nisula, Maria Vistnes, Tiina Ojala, Mattias Molin, Mats Synnergren, Birgitta S Romlin, Sven-Erik Ricksten, Håkan Wåhlander, Albert Gyllencreutz Castellheim
BACKGROUND: This study focuses on biomarkers in infants after open heart surgery, and examines the association of high-sensitive troponin T (hs-cTnT), interleukin-6 (IL-6), and interleukin-8 (IL-8) with postoperative acute kidney injury (AKI), ventilatory support time and need of vasoactive drugs. METHODS: Secondary exploratory study from a double-blinded clinical randomized trial (Mile-1) on 70 infants undergoing open heart surgery with cardiopulmonary bypass (CPB)...
March 26, 2024: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/38529434/recovery-and-survival-of-patients-after-out-of-hospital-cardiac-arrest-a-literature-review-showcasing-the-big-picture-of-intensive-care-unit-related-factors
#11
REVIEW
Srdjan S Nikolovski, Aleksandra D Lazic, Zoran Z Fiser, Ivana A Obradovic, Jelena Z Tijanic, Violetta Raffay
As an important public health issue, out-of-hospital cardiac arrest (OHCA) requires several stages of high quality medical care, both on-field and after hospital admission. Post-cardiac arrest shock can lead to severe neurological injury, resulting in poor recovery outcome and increased risk of death. These characteristics make this condition one of the most important issues to deal with in post-OHCA patients hospitalized in intensive care units (ICUs). Also, the majority of initial post-resuscitation survivors have underlying coronary diseases making revascularization procedure another crucial step in early management of these patients...
February 2024: Curēus
https://read.qxmd.com/read/38528604/is-convenience-really-king-comparative-evaluation-of-catastrophic-costs-due-to-tuberculosis-in-the-public-and-private-healthcare-sectors-of-viet-nam-a-longitudinal-patient-cost-study
#12
JOURNAL ARTICLE
Hoa Binh Nguyen, Luan Nguyen Quang Vo, Rachel Jeanette Forse, Anja Maria Christine Wiemers, Huy Ba Huynh, Thuy Thi Thu Dong, Yen Thi Hoang Phan, Jacob Creswell, Thi Minh Ha Dang, Lan Huu Nguyen, Jad Shedrawy, Knut Lönnroth, Tuan Dinh Nguyen, Luong Van Dinh, Kristi Sidney Annerstedt, Andrew James Codlin
BACKGROUND: In Viet Nam, tuberculosis (TB) represents a devastating life-event with an exorbitant price tag, partly due to lost income from daily directly observed therapy in public sector care. Thus, persons with TB may seek care in the private sector for its flexibility, convenience, and privacy. Our study aimed to measure income changes, costs and catastrophic cost incurrence among TB-affected households in the public and private sector. METHODS: Between October 2020 and March 2022, we conducted 110 longitudinal patient cost interviews, among 50 patients privately treated for TB and 60 TB patients treated by the National TB Program (NTP) in Ha Noi, Hai Phong and Ho Chi Minh City, Viet Nam...
March 25, 2024: Infectious Diseases of Poverty
https://read.qxmd.com/read/38528477/frequency-and-predictors-of-headache-in-the-first-12-months-after-traumatic-brain-injury-results-from-center-tbi
#13
JOURNAL ARTICLE
Emilie Isager Howe, Nada Andelic, Cathrine Brunborg, Marina Zeldovich, Eirik Helseth, Toril Skandsen, Alexander Olsen, Silje C R Fure, Alice Theadom, Katrin Rauen, Benedikte Å Madsen, Bram Jacobs, Joukje van der Naalt, Maria Carmela Tartaglia, Cathrine Elisabeth Einarsen, Gøril Storvig, Erling Tronvik, Cathrine Tverdal, Nicole von Steinbüchel, Cecilie Røe, Torgeir Hellstrøm
BACKGROUND: Headache is a prevalent and debilitating symptom following traumatic brain injury (TBI). Large-scale, prospective cohort studies are needed to establish long-term headache prevalence and associated factors after TBI. This study aimed to assess the frequency and severity of headache after TBI and determine whether sociodemographic factors, injury severity characteristics, and pre- and post-injury comorbidities predicted changes in headache frequency and severity during the first 12 months after injury...
March 25, 2024: Journal of Headache and Pain
https://read.qxmd.com/read/38527782/clinical-characteristics-and-severity-of-respiratory-syncytial-virus-infection-in-korean-children-during-the-post-covid-19-pandemic-period
#14
JOURNAL ARTICLE
Ye Eun Kim, Dayun Kang, Ji Soo Park, Eun Hwa Choi, Ki Wook Yun
We aimed to evaluate the clinical features of respiratory syncytial virus (RSV) infection and risk factors for severe RSV disease among Korean children in 2022/2023. A total of 235 children were identified, and 84.3% were hospitalized. Patients under 3 months and 2 years of age accounted for 20.9% and 54.5%, respectively. Pneumonia was diagnosed in 40.9% of children and bronchiolitis in 23.8%. Respiratory support and intensive care were required in 43.4% and 7.7% of patients, respectively. Haemophilus influenzae nasopharyngeal colonization and the presence of underlying disease showed a significant correlation with severity indicators...
March 13, 2024: Infection & Chemotherapy
https://read.qxmd.com/read/38526511/circumferential-resection-margin-rates-in-esophageal-cancer-resection-oncological-equivalency-and-comparable-clinical-outcomes-between-open-versus-minimally-invasive-techniques-a-retrospective-cohort-study
#15
JOURNAL ARTICLE
Pranav H Patel, Nikhil M Patel, Joseph P Doyle, Hina K Patel, Yousef Alhasan, Alfa Luangsomboon, Nikoletta Petrou, Ricky H Bhogal, Sacheen Kumar, Mohammed A Chaudry, William H Allum
BACKGROUND: Radical surgery for esophageal cancer requires macroscopic and microscopic clearance of all malignant tissue. A critical element of the procedure is achieving a negative circumferential margin (CRM) to minimize local recurrence. The utility of minimally invasive surgery poses challenges in replicating techniques developed in open surgery, particularly for hiatal dissection in esophago-gastrectomy. In this study, the technical approach and clinical and oncological outcomes for open and laparoscopic esophago-gastrectomy are described with particular reference to CRM involvement...
March 25, 2024: International Journal of Surgery
https://read.qxmd.com/read/38525951/frailty-in-the-cardiac-intensive-care-unit-assessment-and-impact
#16
JOURNAL ARTICLE
Mohamad B Moumneh, Yasser Jamil, Kriti Kalra, Naila Ijaz, Greta Campbell, Ajar Kochar, Michael G Nanna, Sean van Diepen, Abdulla A Damluji
Frailty, a clinical syndrome of increased vulnerability, due to diminished cognitive, physical, and physiological reserves is a growing concern in the cardiac intensive care unit (CICU). It contributes to morbidity, mortality, and complications and often exerts a bidirectional association with cardiovascular disease. Althought it predominately affects older adults, frailty can also be observed in younger patients less than 65 years of age, with approximately 30% of those admitted CICU are frail. Acute cardiovascular illness can also impair physical and cognitive functioning among survivors and these survivors often suffer from frailty and functional declines post-CICU discharge...
March 25, 2024: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/38525197/patterns-and-gaps-in-guideline-directed-statin-use-for-atherosclerotic-cardiovascular-disease-by-race-and-ethnicity
#17
JOURNAL ARTICLE
Ashish Sarraju, Xiaowei Yan, Qiwen Huang, Ramzi Dudum, Latha Palaniappan, Fatima Rodriguez
OBJECTIVE: There remain disparities by race and ethnicity in atherosclerotic cardiovascular disease (ASCVD). Statins reduce low-density lipoprotein cholesterol (LDL-c) and improve ASCVD outcomes. ASCVD treatment patterns across disaggregated race and ethnicity groups are incompletely understood. We aimed to evaluate statin use and LDL-c control for ASCVD by race and ethnicity. METHODS: From an electronic health record (EHR)-based cohort from a multisite Northern California health system, we included adults with an ASCVD diagnosis from 2010 to 2021 and at least 2 primary care visits, stratified by race and ethnicity (Non-Hispanic White [NHW], Non-Hispanic Black [Black], Hispanic, and Asian)...
March 2024: American journal of preventive cardiology
https://read.qxmd.com/read/38524515/significant-risk-factors-for-intensive-care-unit-acquired-weakness-a-processing-strategy-based-on-repeated-machine-learning
#18
JOURNAL ARTICLE
Ling Wang, Deng-Yan Long
BACKGROUND: Intensive care unit-acquired weakness (ICU-AW) is a common complication that significantly impacts the patient's recovery process, even leading to adverse outcomes. Currently, there is a lack of effective preventive measures. AIM: To identify significant risk factors for ICU-AW through iterative machine learning techniques and offer recommendations for its prevention and treatment. METHODS: Patients were categorized into ICU-AW and non-ICU-AW groups on the 14th day post-ICU admission...
March 6, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38524255/characterizing-cardiac-function-in-icu-survivors-of-sepsis-a-pilot-study-protocol
#19
JOURNAL ARTICLE
Kevin Garrity, Christie Docherty, Kenneth Mangion, Rosie Woodward, Martin Shaw, Giles Roditi, Benjamin Shelley, Tara Quasim, Philip McCall, Joanne McPeake
BACKGROUND: Sepsis is one of the most common reasons for ICU admission and a leading cause of mortality worldwide. More than one-half of survivors experience significant physical, psychological, or cognitive impairments, often termed post-intensive care syndrome (PICS). Sepsis is recognized increasingly as being associated with a risk of adverse cardiovascular events that is comparable with other major cardiovascular risk factors. It is plausible that sepsis survivors may be at risk of unidentified cardiovascular disease, and this may play a role in functional impairments seen after ICU discharge...
March 2024: CHEST Crit Care
https://read.qxmd.com/read/38524066/upstaging-of-tuberculosis-in-the-post-covid-19-era-a-case-series
#20
Neeru Malik, Meenakshi Sidhar, Nidhi Prabha Sehgal, Anurag Gupta, Ishita Gupta
The COVID-19 pandemic has significantly impacted the global health system as well as the social and economic impact on tuberculosis (TB) treatment and diagnostic services. A high volume of patients diagnosed and treated for TB were impacted by the pandemic restrictions, particularly reduced access to TB services provided by the National Tuberculosis Elimination Programme in India; this in turn increased the number of deaths due to TB. The Indian healthcare system has been struggling with the eradication of TB, and this additional worldwide health crisis caused by SARS-CoV-2 has put the Indian healthcare system under severe stress...
February 2024: Curēus
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