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Keywords Cognitive dysfunction associat...

Cognitive dysfunction associated with PTSD

https://read.qxmd.com/read/37391592/from-childhood-adversity-to-latent-stress-vulnerability-in-adulthood-the-mediating-roles-of-sleep-disturbances-and-hpa-axis-dysfunction
#21
REVIEW
Lisa Simon, Roee Admon
Childhood adversity is a prominent predisposing risk factor for latent stress vulnerability, expressed as an elevated likelihood of developing stress-related psychopathology upon subsequent exposure to trauma in adulthood. Sleep disturbances have emerged as one of the most pronounced maladaptive behavioral outcomes of childhood adversity and are also a highly prevalent core feature of stress-related psychopathology, including post-traumatic stress disorder (PTSD). After reviewing the extensive literature supporting these claims, the current review addresses the notion that childhood adversity-induced sleep disturbances may play a causal role in elevating individuals' stress vulnerability in adulthood...
June 30, 2023: Neuropsychopharmacology
https://read.qxmd.com/read/37390621/the-association-between-post-traumatic-stress-disorder-ptsd-and-cognitive-impairment-a-systematic-review-of-neuroimaging-findings
#22
REVIEW
David Alves de Araujo Junior, Haris I Sair, Matthew E Peters, André F Carvalho, Vivek Yedavalli, Lilja B Solnes, Licia P Luna
BACKGROUND: Accumulating evidence suggests that post-traumatic stress disorder (PTSD) may increase the risk of various types of dementia. Despite the large number of studies linking these critical conditions, the underlying mechanisms remain unclear. The past decade has witnessed an exponential increase in interest on brain imaging research to assess the neuroanatomical underpinnings of PTSD. This systematic review provides a critical assessment of available evidence of neuroimaging correlates linking PTSD to a higher risk of dementia...
June 16, 2023: Journal of Psychiatric Research
https://read.qxmd.com/read/37350239/cognition-and-psychological-well-being-in-adults-with-post-covid-19-condition-and-analyses-of-symptom-sequelae
#23
JOURNAL ARTICLE
V Lynn Ashton Rennison, Cathy J Chovaz, Sandra Zirul
OBJECTIVE: As the coronavirus disease 2019 (COVID-19) pandemic moves into its fourth year, gaining a better clinical understanding of individuals with post COVID-19 condition is paramount. The current study examined the neurocognitive and psychological status of adults with post COVID-19 condition, as well as explored the impact of high psychological burden on objective neurocognitive functioning and the relationship between subjective cognitive concerns and objective neurocognitive findings...
June 23, 2023: Clinical Neuropsychologist
https://read.qxmd.com/read/37344338/effect-of-inhaled-anaesthetics-on-cognitive-and-psychiatric-outcomes-in-critically-ill-adults-a-systematic-review-and-meta-analysis
#24
REVIEW
Sean Cuninghame, Angela Jerath, Kevin Gorsky, Asaanth Sivajohan, Conall Francoeur, Davinia Withington, Lisa Burry, Brian H Cuthbertson, Beverley A Orser, Claudio Martin, Adrian M Owen, Marat Slessarev
BACKGROUND: Sedation of critically ill patients with inhaled anaesthetics may reduce lung inflammation, time to extubation, and ICU length of stay compared with intravenous (i.v.) sedatives. However, the impact of inhaled anaesthetics on cognitive and psychiatric outcomes in this population is unclear. In this systematic review, we aimed to summarise the effect of inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults. METHODS: We searched MEDLINE, EMBASE, and PsycINFO for case series, retrospective, and prospective studies in critically ill adults sedated with inhaled anaesthetics...
August 2023: British Journal of Anaesthesia
https://read.qxmd.com/read/37236069/do-anxiety-sensitivity-cognitive-concerns-and-or-depression-symptoms-independently-explain-sleep-disturbances-in-a-high-anxiety-sensitive-treatment-seeking-sample
#25
JOURNAL ARTICLE
Anastasija Jemcov, Janine V Olthuis, Margo C Watt, Sherry H Stewart
Cognitive models of insomnia posit a role for anxiety sensitivity (AS) in sleep difficulties. While sleep disturbances have been linked to AS, particularly AS cognitive concerns, prior studies have rarely accounted for the correlated construct of depression. We used pre-treatment intervention trial data from 128 high AS, treatment-seeking adults with a DSM-5 diagnosis of an anxiety, depressive, or posttraumatic stress disorder to determine whether AS cognitive concerns and/or depression are independently associated with sleep impairment domains (e...
June 2023: Journal of Anxiety Disorders
https://read.qxmd.com/read/37219529/neuropsychological-function-in-traumatic-brain-injury-and-the-influence-of-chronic-pain
#26
JOURNAL ARTICLE
Nicholas P Cherup, Linda E Robayo, Roberta Vastano, Loriann Fleming, Bonnie E Levin, Eva Widerström-Noga
Cognitive dysfunction, pain, and psychological morbidity all present unique challenges to those living with traumatic brain injury (TBI). In this study we examined (a) the impact of pain across domains of attention, memory, and executive function, and (b) the relationships between pain and depression, anxiety, and post-traumatic stress disorder (PTSD) in persons with chronic TBI. Our sample included 86 participants with a TBI and chronic pain ( n = 26), patients with TBI and no chronic pain ( n = 23), and a pain-free control group without TBI ( n = 37)...
May 23, 2023: Perceptual and Motor Skills
https://read.qxmd.com/read/37189173/objective-and-subjective-cognition-in-survivors-of-covid-19-one-year-after-icu-discharge-the-role-of-demographic-clinical-and-emotional-factors
#27
JOURNAL ARTICLE
Marta Godoy-González, Guillem Navarra-Ventura, Gemma Gomà, Candelaria de Haro, Cristina Espinal, Cristina Fortià, Natalia Ridao, Nuria Miguel Rebanal, Laia Oliveras-Furriols, Carles Subirà, Mercè Jodar, Verónica Santos-Pulpón, Leonardo Sarlabous, Rafael Fernández, Ana Ochagavía, Lluís Blanch, Oriol Roca, Josefina López-Aguilar, Sol Fernández-Gonzalo
BACKGROUND: Intensive Care Unit (ICU) COVID-19 survivors may present long-term cognitive and emotional difficulties after hospital discharge. This study aims to characterize the neuropsychological dysfunction of COVID-19 survivors 12 months after ICU discharge, and to study whether the use of a measure of perceived cognitive deficit allows the detection of objective cognitive impairment. We also explore the relationship between demographic, clinical and emotional factors, and both objective and subjective cognitive deficits...
May 15, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37163480/sounding-the-alarm-what-clinicians-need-to-know-about-physical-emotional-and-cognitive-recovery-after-venoarterial-extracorporeal-membrane-oxygenation
#28
JOURNAL ARTICLE
Kelly C Higa, Kirby Mayer, Christopher Quinn, Lindsey Jubina, Alejandro Suarez-Pierre, Kathryn Colborn, Sarah E Jolley, Kyle Enfield, Joseph Zwischenberger, Carla M Sevin, Jessica Y Rove
OBJECTIVE: We summarize the existing data on the occurrence of physical, emotional, and cognitive dysfunction associated with postintensive care syndrome (PICS) in adult survivors of venoarterial extracorporeal membrane oxygenation (VA-ECMO). DATA SOURCES: MEDLINE, Cochrane Library, EMBASE, Web of Science, and CINAHL databases were searched. STUDY SELECTION: Peer-reviewed studies of adults receiving VA-ECMO for any reason with at least one measure of health-related quality of life outcomes or PICS at long-term follow-up of at least 6 months were included...
May 1, 2023: Critical Care Medicine
https://read.qxmd.com/read/37155265/do-changes-in-dysfunctional-posttraumatic-cognitions-differentially-predict-ptsd-symptom-clusters
#29
JOURNAL ARTICLE
Hannah Schumm, Antje Krüger-Gottschalk, Thomas Ehring, Anne Dyer, Andre Pittig, Keisuke Takano, Georg W Alpers, Barbara Cludius
OBJECTIVE: In recent years, it has been suggested that the modification of dysfunctional posttraumatic cognitions plays a central role as a mechanism of change in cognitive behavioral therapy (CBT) for posttraumatic stress disorder (PTSD). Indeed, several studies have shown that changes in dysfunctional posttraumatic cognitions precede and predict symptom change. However, these studies have investigated the influence on overall symptom severity-despite the well-known multidimensionality of PTSD...
July 2023: Journal of Consulting and Clinical Psychology
https://read.qxmd.com/read/37073774/posttraumatic-stress-disorder-suicidal-ideation-and-stress-the-moderating-role-of-dysfunctional-and-recovery-cognitions
#30
JOURNAL ARTICLE
Kimberly D Gomes, Tyler L Collette, Michael Schlenk, Jason Judkins, Israel Sanchez-Cardona, Bianca Channer, Patricia Ross, George Fredrick, Brian A Moore
OBJECTIVE: Trauma and stressor-related behavioral health conditions are prevalent in military populations and have become a major public health concern in recent years. Individuals who commonly report suicidal ideation often have comorbid mental health diagnoses (i.e., posttraumatic stress disorder; PTSD). However, the mechanisms associated with stress, suicidal ideation, and PTSD are unclear. METHOD: The present study examined the moderating role of dysfunctional and recovery cognitions between (i) PTSD and suicidal ideation, and (ii) stress and suicidal ideation in two distinct samples...
April 19, 2023: Archives of Suicide Research: Official Journal of the International Academy for Suicide Research
https://read.qxmd.com/read/37020493/the-role-of-the-salience-network-in-cognitive-and-affective-deficits
#31
REVIEW
Jakub Schimmelpfennig, Jan Topczewski, Wojciech Zajkowski, Kamila Jankowiak-Siuda
Analysis and interpretation of studies on cognitive and affective dysregulation often draw upon the network paradigm, especially the Triple Network Model, which consists of the default mode network (DMN), the frontoparietal network (FPN), and the salience network (SN). DMN activity is primarily dominant during cognitive leisure and self-monitoring processes. The FPN peaks during task involvement and cognitive exertion. Meanwhile, the SN serves as a dynamic "switch" between the DMN and FPN, in line with salience and cognitive demand...
2023: Frontiers in Human Neuroscience
https://read.qxmd.com/read/36932467/treatment-of-post-traumatic-stress-disorder-in-people-with-dementia-a-structured-literature-review
#32
REVIEW
J E Ruisch, A H M Nederstigt, A van der Vorst, S N Boersma, M T Vink, C M Hoeboer, M Olff, S Sobczak
Post-traumatic stress disorder (PTSD) is associated with cognitive dysfunctions and is an independent risk factor for dementia. A recent study has found the prevalence of PTSD in people with dementia is 4.7%-7.8%. However, little is known about the effectiveness of PTSD treatment for people with dementia. The primary aim of the current study is to review previous studies on the treatment of PTSD in people with dementia. A structured literature review was performed using a 'Preferred Reporting Items for Systematic Reviews and Meta-Analyses' analysis in PubMed, Embase, PsycINFO and CINAHL...
March 17, 2023: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://read.qxmd.com/read/36923289/mitochondrial-dysfunction-in-animal-models-of-ptsd-relationships-between-behavioral-models-neural-regions-and-cellular-maladaptation
#33
REVIEW
Gary B Kaplan, Neysa A Dadhi, Carius S Whitaker
Post-traumatic stress disorder (PTSD) is a trauma-related condition that produces distressing fear memory intrusions, avoidance behaviors, hyperarousal, stress responses, insomnia and other symptoms. This review of rodent models of PTSD examines trauma effects on fear-related learning, cognition, and avoidance, emotional and arousal behaviors and on mitochondrial dysfunction in relevant neural pathways. The review focuses on research that includes four elements: consensus PTSD rodent models, behavioral phenotyping, mitochondrial dysfunction within key neural regions...
2023: Frontiers in Physiology
https://read.qxmd.com/read/36853612/association-of-vitamin-c-thiamine-and-hydrocortisone-infusion-with-long-term-cognitive-psychological-and-functional-outcomes-in-sepsis-survivors-a-secondary-analysis-of-the-vitamin-c-thiamine-and-steroids-in-sepsis-randomized-clinical-trial
#34
RANDOMIZED CONTROLLED TRIAL
Shawniqua Williams Roberson, Samuel Nwosu, Erin M Collar, Amy L Kiehl, Fiona E Harrison, Julie Bastarache, Jo Ellen Wilson, Matthew F Mart, Jonathan E Sevransky, E Wesley Ely, Christopher J Lindsell, James C Jackson
IMPORTANCE: Sepsis is associated with long-term cognitive impairment and worse psychological and functional outcomes. Potential mechanisms include intracerebral oxidative stress and inflammation, yet little is known about the effects of early antioxidant and anti-inflammatory therapy on cognitive, psychological, and functional outcomes in sepsis survivors. OBJECTIVE: To describe observed differences in long-term cognitive, psychological, and functional outcomes of vitamin C, thiamine, and hydrocortisone between the intervention and control groups in the Vitamin C, Thiamine, and Steroids in Sepsis (VICTAS) randomized clinical trial...
February 1, 2023: JAMA Network Open
https://read.qxmd.com/read/36826627/altered-dynamic-functional-connectivity-associates-with-post-traumatic-stress-disorder
#35
JOURNAL ARTICLE
Yingliang Dai, Zhou Zhou, Feng Chen, Li Zhang, Jun Ke, Rongfeng Qi, Guangming Lu, Yuan Zhong
Research has been looking into neural pathophysiology of post-traumatic stress disorder (PTSD) and dynamic functioning connectivity (dFC) applying resting state functional magnetic resonance imaging (rs-fMRI). Previous studies showed that PTSD related impairments are associated with alterations distributed across different brain regions and disorganized functional connectivity, especially in Default Mode Network and the cerebellar area. In this study, we specifically looked into dFC on a whole brain level, and we focused on critical regions such as DMN and cerebellum...
February 24, 2023: Brain Imaging and Behavior
https://read.qxmd.com/read/36772819/neuropsychological-functioning-neurobehavioral-symptoms-and-community-reintegration-in-unstably-housed-veterans-with-mental-health-conditions
#36
JOURNAL ARTICLE
Amber V Keller, Chantal M Muller-Cohn, Tara A Austin, Amy J Jak, Elizabeth W Twamley
Objective: Returning Veterans often have conditions (e.g. posttraumatic stress disorder [PTSD], depression, and history of traumatic brain injury [TBI]) associated with cognitive dysfunction and problems with work, school, housing, and relationships. Rehabilitative efforts in Veterans aim to promote community reintegration, or successful adjustment in one's home, community, and desired social roles. We examined associations between neuropsychological performance, neurobehavioral symptoms, and community reintegration in Veterans...
February 11, 2023: Clinical Neuropsychologist
https://read.qxmd.com/read/36728954/risk-factors-for-positive-post-traumatic-stress-disorder-screening-and-associated-outcomes-in-children-surviving-acute-respiratory-failure-a-secondary-analysis-of-the-randomized-evaluation-of-sedation-titration-for-respiratory-failure-clinical-trial
#37
JOURNAL ARTICLE
Aleksandra E Olszewski, Leslie A Dervan, Mallory B Smith, Lisa A Asaro, David Wypij, Martha A Q Curley, R Scott Watson
OBJECTIVES: To identify risk factors and outcomes associated with a positive post-traumatic stress disorder (PTSD) screen following pediatric acute respiratory failure treated with invasive mechanical ventilation. DESIGN: Nonprespecified secondary analysis of a randomized clinical trial. SETTING: Thirty-one U.S. PICUs. PATIENTS: Children in the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) trial (NCT00814099, ClinicalTrials...
December 23, 2022: Pediatric Critical Care Medicine
https://read.qxmd.com/read/36722118/racial-disparities-in-adversity-during-childhood-and-the-false-appearance-of-race-related-differences-in-brain-structure
#38
JOURNAL ARTICLE
Nathalie M Dumornay, Lauren A M Lebois, Kerry J Ressler, Nathaniel G Harnett
OBJECTIVE: Black Americans in the United States are disproportionately exposed to childhood adversity compared with White Americans. Such disparities may contribute to race-related differences in brain structures involved in regulating the emotional response to stress, such as the amygdala, hippocampus, and prefrontal cortex (PFC). The authors investigated neuroanatomical consequences of racial disparities in adversity. METHODS: The sample included 7,350 White American and 1,786 Black American children (ages 9-10) from the Adolescent Brain Cognitive Development Study (public data release 2...
February 1, 2023: American Journal of Psychiatry
https://read.qxmd.com/read/36669352/increased-top-down-control-of-emotions-during-symptom-provocation-working-memory-tasks-following-a-rct-of-alpha-down-neurofeedback-in-ptsd
#39
JOURNAL ARTICLE
Saurabh Bhaskar Shaw, Andrew A Nicholson, Tomas Ros, Sherain Harricharan, Braeden Terpou, Maria Densmore, Jean Theberge, Paul Frewen, Ruth A Lanius
BACKGROUND: Posttraumatic stress disorder (PTSD) has been found to be associated with emotion under-modulation from the prefrontal cortex and a breakdown of the top-down control of cognition and emotion. Novel adjunct therapies such as neurofeedback (NFB) have been shown to normalize aberrant neural circuits that underlie PTSD psychopathology at rest. However, little evidence exists for NFB-linked neural improvements under emotionally relevant cognitive load. The current study sought to address this gap by examining the effects of alpha-down NFB in the context of an emotional n-back task...
January 3, 2023: NeuroImage: Clinical
https://read.qxmd.com/read/36624888/associations-of-subjective-and-objective-cognitive-functioning-after-covid-19-a-six-month-follow-up-of-icu-ward-and-home-isolated-patients
#40
JOURNAL ARTICLE
Riikka E Pihlaja, Lina-Lotta S Kauhanen, Henriikka S Ollila, Annamari S Tuulio-Henriksson, Sanna K Koskinen, Marjaana Tiainen, Viljami R Salmela, Johanna Hästbacka, Laura S Hokkanen
BACKGROUND: Subjective and objective cognitive dysfunction are reported after COVID-19 but with limited data on their congruence and associations with the severity of the acute disease. The aim of this cohort study is to describe the prevalence of subjective and objective cognitive dysfunction at three and six months after COVID-19 and the associations of subjective cognitive symptoms and psychological and disease-related factors. METHODS: We assessed a cohort of 184 patients at three and six months after COVID-19: 82 patients admitted to the Intensive Care Unit (ICU), 53 admitted to regular hospital wards, and 49 isolated at home...
January 5, 2023: Brain, behavior, & immunity health
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