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Cognitive function in rhinosinusitis

Nicholas R Rowan, Rodney J Schlosser, Kristina A Storck, Kimia G Ganjaei, Zachary M Soler
BACKGROUND: Cognitive dysfunction in chronic rhinosinusitis (CRS) is often overlooked despite potentially broad implications. Earlier work has demonstrated decreased cognitive function in CRS patients at baseline. In this study we sought to prospectively evaluate the impact of initial, appropriate medical therapy on subjective and objective cognitive function, fatigue, and workplace productivity. METHODS: Adult patients with CRS were prospectively enrolled and completed a robust battery of pretreatment quality-of-life and neurocognitive testing, before undergoing appropriate medical therapy with follow-up testing at 6 weeks...
February 27, 2019: International Forum of Allergy & Rhinology
Fatih Arslan, Serdar Tasdemir, Abdullah Durmaz, Fuat Tosun
Chronic rhinosinusitis with nasal polyposis is a chronic inflammatory disease of the respiratory mucosa of the nasal cavity and paranasal sinuses. The aim of this study was investigate the effect of nasal obstruction related to chronic rhinosinusitis with nasal polyposis on cognitive functions. Patients with chronic rhinosinusitis with nasal polyposis causing bilateral total or near total nasal obstruction were enrolled in the study. Symptoms of nasal congestion, loss of smell, postnasal drip, headaches, snoring, concentration difficulties and blunted affect were evaluated by Visual Analog Scale...
August 2018: Cognitive Neurodynamics
Mahboobeh Mahdavinia, Robert P Schleimer, Ali Keshavarzian
Chronic rhinosinusitis (CRS) is a common disease of the upper airways and paranasal sinuses with a marked decline in quality of life (QOL). CRS patients suffer from sleep disruption at a significantly higher proportion (60 to 75%) than in the general population (8-18 %). Sleep disruption in CRS causes decreased QOL and is linked to poor functional outcomes such as impaired cognitive function and depression. Areas covered: A systematic PubMed/Medline search was done to assess the results of studies that have investigated sleep and sleep disturbances in CRS...
May 2017: Expert Review of Anti-infective Therapy
George S Tarasidis, Adam S DeConde, Jess C Mace, Shaelene Ashby, Timothy L Smith, Richard R Orlandi, Jeremiah A Alt
BACKGROUND: Cognitive dysfunction and its relationship to both pain and disease-specific quality of life (QOL) in chronic rhinosinusitis (CRS) have not been investigated previously. We sought to analyze the correlations of pain and disease-specific QOL with cognitive function in CRS. METHODS: Adults with CRS were prospectively enrolled in a cross-sectional study. Participants' cognitive function was assessed using the Cognitive Failures Questionnaire. Pain was characterized using the Short-Form McGill Pain Questionnaire (SF-MPQ) and the Brief Pain Inventory Short Form...
November 2015: International Forum of Allergy & Rhinology
Zachary M Soler, Mark A Eckert, Kristina Storck, Rodney J Schlosser
BACKGROUND: Cognitive dysfunction in patients with chronic rhinosinusitis (CRS) has previously received little attention. Cognitive data generally includes only subjective measures and lack appropriate controls when cognition is considered. The purpose of this study was to characterize dimensions of cognitive function that are affected in patients with CRS compared to a control sample using subjective and objective measures of cognitive function. METHODS: Patients fulfilling diagnostic criteria for CRS and non-CRS controls were recruited from the same clinical reference population...
November 2015: International Forum of Allergy & Rhinology
John Malaty, Irene A C Malaty
Smell and taste disorders can be challenging to diagnose because of the large number of potential etiologies. Patients are often unable to provide a clear history of symptoms, because they frequently cannot distinguish between difficulties with smell and taste. Standardized questionnaires may be helpful in diagnosis. Smell and taste dysfunction have been implicated in loss of appetite, unintended weight loss, malnutrition, and reduced quality of life. Taste dysfunction may be complete or partial, and affect one or more aspects of taste (sweetness, bitterness, sourness, saltiness, and umami [savory])...
December 15, 2013: American Family Physician
Neil Bhattacharyya
BACKGROUND: Chronic rhinosinusitis (CRS) and allergic rhinitis are associated with functional limitations, but these impacts are not known on a population basis. Our objective was to epidemiologically determine functional limitations and workdays lost that are associated with CRS and allergic rhinitis in adults. METHODS: The Medical Expenditure Panel Survey for calendar year 2007 was examined to identify cases of CRS and allergic rhinitis. Functional limitation variables for activity limitation, work limitation, social limitation, and cognitive limitation determined by the survey also were extracted...
March 2012: American Journal of Rhinology & Allergy
Bradley F Marple
Recently, an expanded view of inflammatory disease of the nose and paranasal sinuses, an improved understanding of the functional anatomy of this region, and the development of more sophisticated methods for examining inflammation have led to subtle changes in the field of rhinology. Careful review of the literature suggests that a number of disparate disease processes may serve as cofactors leading to the ultimate development of inflammatory nasal/paranasal sinus disease. Evaluation of cellular infiltrates and inflammatory mediators associated with various forms of rhinologic disease reveals significant overlap among many diseases that were previously thought to be separate disease processes...
October 2003: Otolaryngologic Clinics of North America
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