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Mohammad Mehboudi, Aniello Lampo, Christos Charalambous, Luis A Correa, Miguel Ángel García-March, Maciej Lewenstein
We introduce a novel minimally disturbing method for sub-nK thermometry in a Bose-Einstein condensate (BEC). Our technique is based on the Bose polaron model; namely, an impurity embedded in the BEC acts as the thermometer. We propose to detect temperature fluctuations from measurements of the position and momentum of the impurity. Crucially, these cause minimal backaction on the BEC and hence, realize a nondemolition temperature measurement. Following the paradigm of the emerging field of quantum thermometry, we combine tools from quantum parameter estimation and the theory of open quantum systems to solve the problem in full generality...
January 25, 2019: Physical Review Letters
Shengkai Wang, Ronald K Hanson
A novel method is presented for quantitative two-dimensional temperature measurement in combustion gases. This method, namely spectrally resolved planar laser-induced fluorescence thermometry, utilizes a high-power, wavelength-tunable and narrow-linewidth CW laser to access the spectral lineshapes of a key combustion intermediate, the hydroxyl radical (OH), and enables high-fidelity and calibration-free quantification of non-uniform temperature fields in complex reacting flows. Specifically, the R1 (11)/R1 (7) line pair of the OH A2 Σ+ -X2 Π(0,0) rovibronic band was probed with laser radiation near 306...
February 1, 2019: Optics Letters
Elizabeth K Weidman, Michael G Kaplitt, Kristin Strybing, J Levi Chazen
An 86-year-old right-handed man with medically refractory essential tremor was treated using left-sided MRI-guided focused ultrasound (MRgFUS) thalamotomy targeting the dentatorubrothalamic tract (DRTT) at its intersection with the ventral intermediate nucleus of the thalamus, with immediate symptomatic improvement and immediate postprocedure imaging demonstrating disruption of the DRTT. The patient experienced a partial return of symptoms 9 weeks following the procedure, and MRI demonstrated retraction of the left thalamic ablation site...
January 25, 2019: Journal of Neurosurgery
Georgia K Chaseling, Dustin R Allen, Steve Vucic, Michael Barnett, Elliot Frohman, Scott L Davis, Ollie Jay
PURPOSE: To reassess the notion that people with multiple sclerosis (MS) do not demonstrate an elevated resting core temperature when measured using best-practice precision thermometry. METHOD: Across two international data collection sites (Australia and USA), twenty-eight relapsing-remitting MS patients and 27 aged-matched controls (CON) were exposed to either 30 °C, 30% relative humidity (RH) (Sydney) or 25 °C, 30% RH (Dallas). Resting rectal (Tre ) and esophageal (Teso ) temperature and resting oxygen consumption (VO2 ) was measured in MS (n = 28) and CON (n = 27) groups who completed the 25 °C and 30 °C trials...
January 4, 2019: Multiple Sclerosis and related Disorders
M Daëron, R N Drysdale, M Peral, D Huyghe, D Blamart, T B Coplen, F Lartaud, G Zanchetta
Oxygen-isotope thermometry played a critical role in the rise of modern geochemistry and remains extensively used in (bio-)geoscience. Its theoretical foundations rest on the assumption that 18 O/16 O partitioning among water and carbonate minerals primarily reflects thermodynamic equilibrium. However, after decades of research, there is no consensus on the true equilibrium 18 O/16 O fractionation between calcite and water (18 αcc/w ). Here, we constrain the equilibrium relations linking temperature, 18 αcc/w , and clumped isotopes (Δ47 ) based on the composition of extremely slow-growing calcites from Devils Hole and Laghetto Basso (Corchia Cave)...
January 25, 2019: Nature Communications
Ana Navarro-Serra, Héctor Sanz-Cabañes
BACKGROUND: Internal temperature data are essential for clinical evaluation in veterinary medicine. During the last decade, new thermometry devices have been developed. Identification microchips with a temperature sensor offer double utility to clinicians by satisfying animal identification regulations and providing a non-invasive method for temperature measurement. METHODS: During this study, 26 healthy vervet monkeys (Chlorocebus pygerythrus) were implanted with a subcutaneous temperature transponding microchip...
January 24, 2019: Journal of Medical Primatology
Jon T Willie, James G Malcolm, Matthew A Stern, Lindsay O Lowder, Stewart G Neill, Brian T Cabaniss, Daniel L Drane, Robert E Gross
OBJECTIVE: Magnetic resonance (MR) thermography-guided laser interstitial thermal therapy, or stereotactic laser ablation (SLA), is a minimally invasive alternative to open surgery for focal epilepsy caused by cerebral cavernous malformations (CCMs). We examined the safety and effectiveness of SLA of epileptogenic CCMs. METHODS: We retrospectively analyzed 19 consecutive patients who presented with focal seizures associated with a CCM. Each patient underwent SLA of the CCM and adjacent cortex followed by standard clinical and imaging follow-up...
January 17, 2019: Epilepsia
Dionyssios Mintzopoulos, Eva-Maria Ratai, Julian He, Ramon Gilberto Gonzalez, Marc J Kaufman
PURPOSE: To evaluate brain temperature effects of early simian immunodeficiency virus (SIV) infection in rhesus macaques using proton magnetic resonance spectroscopy (MRS) thermometry (MRSt) and to determine whether temperature correlates with brain choline or myo-inositol levels. METHODS: Brain temperature was retrospectively determined in serial MRS scans that had been acquired at baseline and at 2 and 4 weeks post-SIV infection (wpi) in 16 monkeys by calculating the chemical shift difference between N-acetylaspartate (NAA) and water peaks in sequentially acquired water-suppressed and unsuppressed point-resolved spectroscopy (PRESS) spectra...
January 16, 2019: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
Bryant T Svedin, Allison Payne, Dennis L Parker
PURPOSE: Implement simultaneous proton resonance frequency (PRF) shift and T1 measurements with equivalent temporal resolution using a single reference variable flip angle method. This novel method allows for simultaneous thermometry in both aqueous and fatty tissue. METHODS: This method acquires a single reference image at the lower flip angle and all dynamic images at the higher angle. T1 is calculated using a single reference variable flip angle method, which accounts for the reference image temperature remaining constant...
January 16, 2019: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
Xunchen Liu, Guoqing Wang, Jianyi Zheng, Liangliang Xu, Sirui Wang, Lei Li, Fei Qi
The detailed understandings of temperature profiles and flow-flame interaction in unsteady premixed swirling flames are crucial for the development of low emission turbine engines. Here, a phase-locked tomographic reconstruction technique measuring the large absorption cross section of CO2 at its mid-infrared fundamental band around 4.2 μm is used to acquire the flame temperature and in situ CO2 volume fraction distribution in a turbulent premixed swirling flame under different levels of external acoustic forcing amplitude...
November 26, 2018: Optics Express
Chengxi Zhu, Matthew J Hobbs, Matthew P Grainger, Jon R Willmott
We present a wide field of view (FOV) infrared scanning system, designed for single-pixel near-infrared thermal imaging. The scanning system consisted of a two-axis micro-electromechanical system (MEMS) mirror that was incorporated within the lens. The optical system consisted of two groups of lenses and a silicon avalanche photodiode. The system was designed for both the production of thermal images and also to utilize the techniques of radiation thermometry to measure the absolute temperature of targets from 500°C to 1100°C...
December 20, 2018: Applied Optics
Henrik Odéen, Dennis L Parker
OBJECTIVES: To develop, test and evaluate improved 2D and 3D protocols for proton resonance frequency shift magnetic resonance temperature imaging (MRTI) of laser interstitial thermal therapy (LITT). The objective was to develop improved MRTI protocols in terms of temperature measurement precision and volume coverage compared to the 2D MRTI protocol currently used with a commercially available LITT system. METHODS: Four different 2D protocols and four different 3D protocols were investigated...
January 15, 2019: Lasers in Surgery and Medicine
Dominic Zelenak, Venkateswaran Narayanaswamy
Experiments were performed to demonstrate a dual-wavelength excitation krypton planar laser-induced fluorescence (Kr PLIF)-based 2D temperature imaging technique in a laminar non-sooting CH4 /N2 diffusion flame. The technique exploits the thermochemical dependence of the overlap integral arising from Kr absorption and excitation laser spectra to yield the temperature without the need to know the local mixture composition. The choice of the two excitation wavelengths is made using the knowledge of the fuel mixture and pressure...
January 15, 2019: Optics Letters
Bolang Fang, Zhenrong Zhang, Guohua Li, Bo Tao, Sheng Wang, Zhiyun Hu, MingYing Song
Nonlinear excitation regime two-line atomic fluorescence (NTLAF) is a promising two-dimensional (2D) thermometry technique for turbulent sooty flames. However, the complexity of calibrating three system parameters and expensive instruments restricts the application of the current NTLAF technique. Here we propose a simple and cheap NTLAF measurement approach based on a one-parameter model and tunable diode laser absorption spectroscopy (TDLAS) calibration. Using this methodology, only one system parameter, instead of three as in traditional NTLAF, is to be calibrated by path-averaged temperature acquired by the TDLAS technique...
January 15, 2019: Optics Letters
Michael D Gray, Paul C Lyon, Christophoros Mannaris, Lisa K Folkes, Michael Stratford, Leticia Campo, Daniel Y F Chung, Shaun Scott, Mark Anderson, Robert Goldin, Robert Carlisle, Feng Wu, Mark R Middleton, Fergus V Gleeson, Constantin C Coussios
Purpose To demonstrate the feasibility and safety of using focused ultrasound planning models to determine the treatment parameters needed to deliver volumetric mild hyperthermia for targeted drug delivery without real-time thermometry. Materials and Methods This study was part of the Targeted Doxorubicin, or TARDOX, phase I prospective trial of focused ultrasound-mediated, hyperthermia-triggered drug delivery to solid liver tumors ( identifier NCT02181075). Ten participants (age range, 49-68 years; average age, 60 years; four women) were treated from March 2015 to March 2017 by using a clinically approved focused ultrasound system to release doxorubicin from lyso-thermosensitive liposomes...
January 15, 2019: Radiology
Ilya Kolesnikov, Alexey Kalinichev, Mikhail Kurochkin, Daria Mamonova, Eugenii Kolesnikov, Erkki Lähderanta, Mikhail Mikhailov
Achieving a combination of real-time diagnosis and therapy in a single platform with sensitive thermometry and efficient heat production is a crucial step towards controllable photo-thermal therapy. Here, Nd3+-doped Y2O3 nanoparticles prepared by combined Pechini-foaming technique operating in first and second biological windows were demonstrated as thermal sensors within wide temperature range of 123-873 K and heaters with temperature increase by 100 K. Thermal sensing was performed based on various approaches: luminescence intensity ratio (electronic levels; Stark sublevels), spectral line position and line bandwidth were used as temperature dependent parameters...
January 9, 2019: Nanotechnology
Mehri Mirrahimi, Ziaeddin Abed, Jaber Beik, Isaac Shiri, Amin Shiralizadeh Dezfuli, Vahid Pirhajati Mahabadi, S Kamran Kamrava, Habib Ghaznavi, Ali Shakeri-Zadeh
The current interest in cancer research is being shifted from individual therapy to combinatorial therapy. In this contribution, a novel multifunctional nanoplatform comprising alginate nanogel co-loaded with cisplatin and gold nanoparticles (AuNPs) has been firstly developed to combine photothermal therapy and chemotherapy. The antitumor efficacy of the as-prepared nanocomplex was tested against CT26 colorectal tumor model. The nanocomplex showed an improved chemotherapy efficacy than free cisplatin and caused a significantly higher tumor inhibition rate...
January 3, 2019: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
Trevor L Courtney, Christopher J Kliewer
Time-resolved pure-rotational hybrid femtosecond/picosecond coherent anti-Stokes Raman spectroscopy (fs/ps RCARS) of oxygen (O2 ) is performed at pressures from ∼0.04 to 0.4 atm. As the RCARS spectra evolve with probe delay, they exhibit coherence beating between unresolved S-branch triplet transitions (Δ N = 2, Δ J = 2). The time-domain fitting of the RCARS signal intensity enables the determination of these transition frequency separations, which are as low as 480 MHz (0.016 cm-1 ). Additionally, we study the underlying pressure-dependent dynamics and the signatures of the time-domain triplet signals compared to the simple decays associated with the O2 self-broadened linewidths...
December 21, 2018: Journal of Chemical Physics
Ethan I Kleinbaum, Stephen A Lyon
We have developed a method to probe the temperature of surface state electrons (SSE) above a superfluid helium-4 surface using the Seebeck effect. In contrast to previously used SSE thermometry, this technique does not require detailed knowledge of the nonlinear mobility. We demonstrate the use of this method by measuring the heating of SSE at 1.6 K in a microchannel device with 0.6  μm deep helium. In this regime, both vapor atom scattering and 2-ripplon scattering contribute to energy relaxation to which we compare our measurements...
December 7, 2018: Physical Review Letters
Kristina Shrestha, Arwa A Alaulamie, Ali Rafiei Miandashti, Hugh H Richardson
Hexagonal upconverting nanoparticles (UCNPs) of NaYF4 :Er3+ ,Yb3+ (ca. 300 nm) have been widely used to measure the temperature at the nanoscale using luminescence ratio thermometry. However, several factors limit their applications. For example, changes in the peak shape, mainly is the S-band emission, hinders their ability to be used as a universal temperature sensor. Herein, we introduce a universal calibration protocol for NaYF4 :Er3+ ,Yb3+ upconverting nanoparticles that is robust to environmental changes and gives a precise temperature measurement...
2018: Beilstein Journal of Nanotechnology
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