keyword
https://read.qxmd.com/read/38186459/improvement-of-intestinal-pseudo-obstruction-by-total-parenteral-nutrition-in-a-young-woman-with-mitochondrial-myopathy-encephalopathy-lactic-acidosis-and-stroke-like-episodes-a-case-report
#21
Naoto Sakamoto, Shuhei Hamada, Hiroki Takahashi, Rumi Satou, Masatsune Suzuki, Tetsuhiro Maeno
Patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), a mitochondrial disease, develop various types of organ failure, including intestinal pseudo-obstruction (IPO). We treated a patient with IPO that improved with total parenteral nutrition.  A 20-year-old woman with a two-year history of diabetes mellitus was taking sitagliptin but her hemoglobin A1c (HbA1c) levels began increasing. After receiving metformin, she suffered a stroke-like attack and was diagnosed with MELAS...
December 2023: Curēus
https://read.qxmd.com/read/38143971/acute-colonic-pseudo-obstruction-acpo-a-rare-case-of-caecal-perforation-post-caesarean-section
#22
Bhavya Arvind Rao, Sagar Ramesh Ambre, Pragati Sanganeria, Shyam Uttam Rathod, Jayashri Pandya
No abstract text is available yet for this article.
December 2023: Journal of Obstetrics and Gynaecology of India
https://read.qxmd.com/read/38111811/a-colonic-lipoma-causing-obstruction-a-case-report-and-review-of-literature
#23
Polyxeni Pichioni, Dimitrios Kokkinovasilis, Stylianos Stylianou, Saant Al Mogrampi
Colonic lipomas are rare benign lesions of the gastrointestinal tract. They are asymptomatic in the majority of cases. This report aims to present a case involving a 65-year-old female patient reporting rectal bleeding, loss of appetite, and alteration in bowel habits. First, she was submitted to colonoscopy which revealed a sizable ulcerative polypoid lesion in the descending colon, displaying histological characteristics consistent with a hyperplastic polyp and devoid of malignancy indications. An abdominal computed tomography followed which showed diffuse thickening of the colonic wall in the descending colon, resulting in nearly complete luminal obstruction and also a submucosal lipoma measuring 2...
December 2023: Curēus
https://read.qxmd.com/read/38083505/evaluation-of-pacing-parameters-to-induce-contractions-in-the-small-intestine
#24
JOURNAL ARTICLE
Nipuni D Nagahawatte, Recep Avci, Niranchan Paskaranandavadivel, Leo K Cheng
Postoperative ileus and chronic intestinal pseudo-obstruction are intestinal motility disorders that can compromise bowel function resulting in a significant reduction in quality of life and prolonged hospital stays. While medication and nutritional support provides relief for some patients, a significant patient population remains untreated. Therefore, alternative treatment options are required. A novel framework that enables small intestine pacing and video mapping of the contractile response was developed...
July 2023: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://read.qxmd.com/read/38065609/dilated-gut-conditions-diagnosis-and-management
#25
JOURNAL ARTICLE
Amir Mari, Anton Emmanuel
Dilatation of the gut occurs in response to either mechanical obstruction or aperistalsis. The hallmark features are symptoms of bowel obstruction with vomiting, constipation, abdominal pain and distension. This review will primarily deal with the non-mechanical causes of gut dilatation, both intestinal and colonic, and differentiate between acute and chronic presentations.
November 2023: Clinical Medicine: Journal of the Royal College of Physicians of London
https://read.qxmd.com/read/38061549/vasoactive-intestinal-polypeptide-plays-a-key-role-in-the-microbial-neuroimmune-control-of-intestinal-motility
#26
JOURNAL ARTICLE
Xiaopeng Bai, Giada De Palma, Elisa Boschetti, Yuichiro Nishihara, Jun Lu, Chiko Shimbori, Anna Costanzini, Zarwa Saqib, Narjis Kraimi, Sacha Sidani, Siegfried Hapfelmeier, Andrew J Macpherson, Elena F Verdu, Roberto De Giorgio, Stephen M Collins, Premysl Bercik
BACKGROUND AND AIMS: Although chronic diarrhea and constipation are common, the treatment is symptomatic as their pathophysiology is poorly understood. Accumulating evidence suggests that the microbiota modulates gut function but the underlying mechanisms are unknown. We therefore investigated the pathways by which microbiota modulates gastrointestinal motility in different sections of the alimentary tract. METHODS: Gastric emptying, intestinal transit, muscle contractility, acetylcholine release, gene expression and vasoactive intestinal polypeptide (VIP) immunoreactivity were assessed in wild-type and Myd88-/- Trif-/- mice in germ-free, gnotobiotic and SPF conditions...
December 5, 2023: Cellular and Molecular Gastroenterology and Hepatology
https://read.qxmd.com/read/38044152/small-cell-lung-carcinoma-with-gastrointestinal-pseudo-obstruction-as-a-paraneoplastic-neurological-syndrome-elicited-by-an-immune-checkpoint-inhibitor
#27
JOURNAL ARTICLE
Atsushi Saitou, Makoto Shioya, Yuta Nagahisa, Aoi Haseyama, Rumi Niwa, Jyuri Tsuchimoto, Hirofumi Chiba
Gastrointestinal pseudo-obstruction (GIPO) is a phenotype of the paraneoplastic neurological syndrome (PNS). We herein report a case of small-cell lung carcinoma (SCLC) with GIPO elicited by an immune checkpoint inhibitor (ICI). A 75-year-old man with SCLC developed intractable intestinal obstruction after receiving one course of anticancer drugs (durvalumab, etoposide, and carboplatin). The serum anti-Hu antibody (Hu-Ab) was positive, and the patient was diagnosed with GIPO. Corticosteroid treatment did not improve the GIPO, and the patient died...
December 4, 2023: Internal Medicine
https://read.qxmd.com/read/37994282/chronic-intestinal-pseudo-obstruction-in-adults-a-practical-guide-to-identify-patient-subgroups-that-are-suitable-for-more-specific-treatments
#28
REVIEW
Guido Basilisco, Margherita Marchi, Marina Coletta
Chronic intestinal pseudo-obstruction is a rare and heterogeneous syndrome characterized by recurrent symptoms of intestinal obstruction with radiological features of dilated small or large intestine with air/fluid levels in the absence of any mechanical occlusive lesion. Several diseases may be associated with chronic intestinal pseudo-obstruction and in these cases, the prognosis and treatment are related to the underlying disease. Also, in its "primary or idiopathic" form, two subgroups of patients should be determined as they require a more specific therapeutic approach: patients whose chronic intestinal pseudo-obstruction is due to sporadic autoimmune/inflammatory mechanisms and patients whose neuromuscular changes are genetically determined...
January 2024: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://read.qxmd.com/read/37989898/evaluation-of-18-ct-signs-in-diagnosing-cecal-volvulus-a-multi-reader-retrospective-study
#29
JOURNAL ARTICLE
Moataz Soliman, Michael Magnetta, Abraham Salinas, Richard S Feinn, Yuri S Velichko, Frank H Miller, Linda C Kelahan
PURPOSE: To assess the diagnostic performance and reliability of 18 CT signs to diagnose cecal volvulus, a surgical emergency, versus a group of non-volvulus mimickers. MATERIALS AND METHODS: Four radiologists retrospectively and independently assessed 18 CT signs in 191 patients with cecal volvulus (n = 63) or a non-volvulus control group ((n = 128), including cecal bascule (n = 19), mobile cecum (n = 95), and colonic pseudo-obstruction (n = 14)) at a single institution from 2013 to 2021...
November 21, 2023: Abdominal Radiology
https://read.qxmd.com/read/37973225/endoscopic-management-of-colonic-obstruction
#30
REVIEW
Ahmad F Aboelezz, Mohamed O Othman
Large bowel obstruction is a serious event that occurs in approximately 25% of all intestinal obstructions. It is attributed to either benign, malignant, functional (pseudo-obstruction), or mechanical conditions. Benign etiologies of colonic obstructions include colon volvulus, anastomotic strictures, radiation injury, ischemia, inflammatory processes such as Crohn's disease, diverticulitis, bezoars, and intussusception.
January 2024: Gastrointestinal Endoscopy Clinics of North America
https://read.qxmd.com/read/37929992/current-insights-on-chronic-intestinal-dysmotility-pseudo-obstruction-and-enteric-dysmotility
#31
JOURNAL ARTICLE
Luis Gerardo Alcalá González, Carolina Malagelada
Chronic intestinal dysmotility is a rare and debilitating digestive disorder characterized by symptoms of mechanical obstruction without an organic lesion. It has diverse causes and involves various pathological mechanisms. Small bowel manometry is the preferred diagnostic method, particularly for patients with severe and progressive symptoms. The condition can be categorized as intestinal pseudo-obstruction and enteric dysmotility, both entities share abnormal small bowel motility, but with important differences in prognosis and management...
November 6, 2023: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/37919206/life-threatening-bowel-complications-in-adults-with-duchenne-muscular-dystrophy-a-case-series
#32
JOURNAL ARTICLE
Luca Nart, Mahalekshmi Desikan, Anton Emmanuel, Ros Quinlivan
Duchenne muscular dystrophy is a progressive muscle wasting disease caused by pathogenic variants in DMD. Gastrointestinal involvement is increasingly recognised in older patients and can manifest as life-threatening bowel dysmotility. We describe a series of adults with Duchenne muscular dystrophy who developed either severe colonic pseudo-obstruction or sigmoid volvulus requiring urgent assessment and intervention. The presentations varied in their clinical picture and outcomes, but together highlight the complexity of managing gastrointestinal complications in this cohort of patients...
October 13, 2023: Neuromuscular Disorders: NMD
https://read.qxmd.com/read/37916112/a-case-of-comorbidity-of-schizophrenic-catatonia-and-chronic-intestinal-pseudo-obstruction-successfully-managed-with-lorazepam
#33
Yang Cao, Weixin Wang, Jiong Chen, Bo Jiang, Sugai Liang, Xianyu Chen, Hui Dong
It is challenging to manage schizophrenic catatonia and comorbid chronic intestinal pseudo-obstruction (CIPO). The pathology of catatonia is unclear. There are few reports or research on this issue. In this case, we present a middle-aged woman diagnosed with schizophrenia with catatonic features and comorbid CIPO. In the treatment process, modified electroconvulsive therapy (mECT) improved her stupor and CIPO partially. Lorazepam alleviated her stupor and CIPO completely. It is the first report describing complete remission with lorazepam in patient suffering from comorbid schizophrenic catatonia and CIPO, which may benefit the exploration of pathophysiology and treatment of comorbidity of schizophrenia with catatonia and CIPO...
October 2023: Heliyon
https://read.qxmd.com/read/37870265/treatment-of-hypokalemia-with-amiloride-unmasked-hypercalcemia-and-hyperparathyroidism-a-case-report
#34
JOURNAL ARTICLE
Alexa E Golbus, Natalie Freidin
Colonic pseudo-obstruction, also called Ogilvie's syndrome, occurs due to impaired intestinal propulsion, and may be caused by electrolyte imbalances such as hypokalemia and some endocrine disorders such as hyperparathyroidism. Secretory diarrhea due to intestinal pseudo-obstruction can cause hypokalemia. Diuretics such as amiloride can be used to treat hypokalemia, however in this case, treatment with amiloride induced hypercalcemia and unmasked hyperparathyroidism. A 73-year-old female with a history of hypertension and parathyroid adenoma presented with recurrent colonic pseudo-obstruction and chronic hypokalemia...
October 23, 2023: Clinical Nephrology
https://read.qxmd.com/read/37868365/a-percutaneous-endoscopic-colostomy-tube-to-the-rescue
#35
Laith Numan, Tim Brotherton, Michelle Baliss, Soumojit Ghosh, Vladimir Lamm, Coen Klos, Gregory Sayuk, Michael Presti, Jill Elwing
Percutaneous endoscopic colostomy (PEC) tube placement is a minimally invasive procedure used to treat recurrent colonic pseudo-obstruction, sigmoid volvulus, chronic intractable constipation, and neurogenic bowel. PEC is a viable treatment alternative for patients who have failed conservative therapies and are deemed high risk for surgical management. We present a case of acute colonic pseudo-obstruction after Clostridioides difficile infection that was unresponsive to medical treatment or endoscopic decompression...
October 2023: ACG Case Reports Journal
https://read.qxmd.com/read/37868240/autoimmune-lupus-enteritis-with-pan-gastrointestinal-involvement-in-an-adult-patient-with-systemic-lupus-erythematosus-complete-response-to-belimumab
#36
Mohammed R Shaik, Nishat A Shaik, Yuting Huang, Ankur Pandey, Erika Wheeler, Jamal Mikdashi
Autoimmune lupus enteritis in systemic lupus erythematosus (SLE) is a rare manifestation that comprises of gastrointestinal tract inflammation with supportive images and/or biopsy findings. We report a unique case of widespread lupus enteritis occurring late in the disease process and in isolation without additional features of active SLE but in the presence of SLE serological activity. There was no clear evidence of active mesenteric vasculitis, intestinal pseudo-obstruction, protein-losing enteropathy, or coagulopathy by imaging or histopathology...
2023: Journal of Community Hospital Internal Medicine Perspectives
https://read.qxmd.com/read/37868188/chronic-pseudo-obstruction-of-the-sigmoid-colon-a-case-report
#37
Ivan Vulić, Matija Šestan-Peša, Dubravka Mužina Mišić, Ivana Pavić, Mario Živković, Ivan Budimir, Davor Hrabar, Neven Ljubičić, Marko Nikolić
Chronic intestinal pseudo-obstruction (CIPO) is a rare syndrome characterized by signs of intestinal obstruction lasting for 6 months or more, in the absence of a definitive cause of obstruction. We report a case of CIPO in a 49-year-old female patient with a 6-month history of ongoing irregular bowel movements, manifested as constipation and diarrhea accompanied by abdominal pain and bloated feeling. Contrast-enhanced abdominal computed tomography and magnetic resonance enterography revealed focal thickening of a segment of the lienal flexure and intermittent areas of wider and narrower caliber along the sigmoid colon...
December 2022: Acta Clinica Croatica
https://read.qxmd.com/read/37865031/challenges-in-the-identification-of-nocturnal-respiratory-events-in-adult-patients-affected-by-spinal-muscular-atrophy
#38
JOURNAL ARTICLE
Grazia Crescimanno, Antonino Lupica, Vito Tomasello, Vincenzo Di Stefano, Filippo Brighina, Oreste Marrone
No abstract text is available yet for this article.
October 12, 2023: Sleep Medicine
https://read.qxmd.com/read/37864325/ogilvie-s-syndrome-in-a-patient-at-23-weeks-of-pregnancy-report-of-a-rare-case-with-successful-surgical-intervention
#39
JOURNAL ARTICLE
Bartosz Wilczyński, Jan Śnieżyński
BACKGROUND Ogilvie's syndrome (acute colonic pseudo-obstruction) is a syndrome characterized by symptoms suggestive of intestinal obstruction without an identifiable mechanical cause. It presents with excessive dilation of the loops of the large intestine. The treatment options include conservative management, endoscopic methods, and surgical intervention. If appropriate treatment is not implemented promptly, this syndrome can lead to life-threatening complications for the patient. Acute colonic pseudo-obstruction typically occurs in elderly individuals with numerous chronic diseases, extensive surgeries, or trauma...
October 21, 2023: American Journal of Case Reports
https://read.qxmd.com/read/37842440/ogilvie-s-syndrome-secondary-to-narcotics-complicated-by-colonic-perforation
#40
Lauren Punter, Raydiene Doorgen, Penelope Mashburn
Ogilvie's syndrome is a condition characterized by colonic dilation in the absence of mechanical obstruction. This case report presents a patient who was immobile and hospitalized for several months following a motor vehicle accident that left the patient paralyzed, who subsequently developed Ogilvie's syndrome. The aim of this study is to briefly discuss the clinical presentation, diagnostic workup, and management of Ogilvie's syndrome. This article also discusses the impact of narcotics and the possible association with Ogilvie's syndrome in this patient...
September 2023: Curēus
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