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https://read.qxmd.com/read/30771409/attenuation-of-adverse-effects-of-noise-induced-hearing-loss-on-adult-neurogenesis-and-memory-in-rats-by-intervention-with-adenosine-a-2a-receptor-agonist
#1
Manish Shukla, Koustav Roy, Charanjeet Kaur, Devasharma Nayak, K V Mani, Sangeeta Shukla, Neeru Kapoor
Hearing loss and cognitive decline are commonly associated with aging and morbidity. Present clinical interest lies in whether peripheral hearing loss promotes cognitive decline and if prophylaxis with selective adenosine receptor agonist CGS21680 effectively mitigates the adverse effects. In the current study, male Sprague Dawley rats weighing 200-250 gm were randomly allocated into three groups: Group 1) rats exposed to 100 dB SPL white noise, 2 hours a day for 15 consecutive days, 2) rats supplemented with an adenosine receptor agonist, CGS21680 at 100 μg/kg/day prior to noise exposure and 3) unexposed control rats...
February 13, 2019: Brain Research Bulletin
https://read.qxmd.com/read/30766449/cochlear-implantation-as-a-treatment-for-single-sided-deafness-and-asymmetric-hearing-loss-a-randomized-controlled-evaluation-of-cost-utility
#2
Mathieu Marx, Nadège Costa, Benoit Lepage, Soumia Taoui, Laurent Molinier, Olivier Deguine, Bernard Fraysse
Background: Single-sided deafness (SSD) and asymmetric hearing loss (AHL) have recently been proposed as a new indication for cochlear implantation. There is still no recommended treatment for these hearing deficits, and most options considered rely on the transfer of sound from the poor ear to the better ear, using Contralateral Routing of the Signal (CROS) hearing aids or bone conduction (BC) devices. In contrast, cochlear implantation allows the poor ear to be stimulated and binaural hearing abilities to be partially restored...
2019: BMC Ear, Nose, and Throat Disorders
https://read.qxmd.com/read/30744951/a-study-of-auditory-localization-mechanism-based-on-thought-experiments
#3
REVIEW
Yi-de Zhang, Wei Liu
The focus of this study is auditory localization. Based on wave mechanics and structural mechanics, we analyze the sound field encircling external ear and the function of the soft tissues in middle ear respectively. And then, with the help of two rules, some details of the generation of spatial hearing are revealed. For auditory direction perception, three semicircular canals work as the reference coordinate system, and the cues are the direction of the concentrated force acting on tympanic membrane and the synchronous stress state...
January 28, 2019: Physics of Life Reviews
https://read.qxmd.com/read/30741905/remote-programming-of-cochlear-implants
#4
Heidi K Slager, Jamie Jensen, Kristin Kozlowski, Holly Teagle, Lisa R Park, Allison Biever, Megan Mears
OBJECTIVE: This study investigated the safety and efficacy of remote programming of cochlear implants. STUDY DESIGN: Single-subject design SETTING:: Four North American clinical sites PATIENTS:: Forty cochlear implant recipients aged 12 years or older INTERVENTION:: Subjects had their cochlear implants programmed at a location that was remote from their audiologist using telecommunication with and without the support of a facilitator. MAIN OUTCOME MEASURES: Consonant-Nucleus-Consonant (CNC) word scores and the Speech, Spatial, and Qualities of Hearing Scale-C (SSQ-C) were compared using the subject's in-office MAP (program) and MAPs programmed remotely with and without the assistance of a facilitator...
March 2019: Otology & Neurotology
https://read.qxmd.com/read/30710924/determining-the-energetic-and-informational-components-of-speech-on-speech-masking-in-listeners-with-sensorineural-hearing-loss
#5
Gerald Kidd, Christine R Mason, Virginia Best, Elin Roverud, Jayaganesh Swaminathan, Todd Jennings, Kameron Clayton, H Steven Colburn
The ability to identify the words spoken by one talker masked by two or four competing talkers was tested in young-adult listeners with sensorineural hearing loss (SNHL). In a reference/baseline condition, masking speech was colocated with target speech, target and masker talkers were female, and the masker was intelligible. Three comparison conditions included replacing female masker talkers with males, time-reversal of masker speech, and spatial separation of sources. All three variables produced significant release from masking...
January 2019: Journal of the Acoustical Society of America
https://read.qxmd.com/read/30694378/consequences-of-hearing-aid-acclimatization-on-allrs-and-its-relationship-with-perceived-benefit-and-speech-perception-abilities
#6
Megha, Sandeep Maruthy
OBJECTIVE: The study aimed to track long latency responses over a period of hearing aid use in naïve hearing aid users, and study its relationship with change in speech perception abilities and perceived benefit. METHODS: Thirty adults in the age range of 23-60 years with moderate sensorineural hearing loss participated in the study. Auditory late latency responses (ALLRs), signal-to-noise ratio - 50 (SNR-50), and scores of speech spatial and qualities questionnaire (SSQ) were measured three times over a period of 2 months of hearing aid use...
January 29, 2019: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/30660682/audiologist-availability-and-supply-in-the-united-states-a-multi-scale-spatial-and-political-economic-analysis
#7
Arrianna Marie Planey
This study employs statistical modeling and mapping techniques to analyze the availability and accessibility of audiologists (practitioners who diagnose and treat hearing loss) in the United States at the county scale. The goal is to assess the relationships between socio-demographic and structural factors (such as health policy and clinical programs which train audiologists) and audiologist availability. These associations are analyzed at the county level, via a mixed effects hurdle model. At the county level, the proportion of older adults reporting difficulty hearing is negatively associated with audiologist supply...
January 11, 2019: Social Science & Medicine
https://read.qxmd.com/read/30651333/representation-of-auditory-motion-directions-and-sound-source-locations-in-the-human-planum-temporale
#8
Ceren Battal, Mohamed Rezk, Stefania Mattioni, Jyothirmayi Vadlamudi, Olivier Collignon
The ability to compute the location and direction of sounds is a crucial perceptual skill to efficiently interact with dynamic environments. How the human brain implements spatial hearing is however poorly understood. In our study, we used fMRI to characterize the brain activity of male and female humans listening to left, right, up and down moving as well as static sounds. Whole brain univariate results contrasting moving and static sounds varying in their location revealed a robust functional preference for auditory motion in bilateral human Planum Temporale (hPT)...
January 16, 2019: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://read.qxmd.com/read/30651330/amplification-and-suppression-of-traveling-waves-along-the-mouse-organ-of-corti-evidence-for-spatial-variation-in-the-longitudinal-coupling-of-outer-hair-cell-generated-forces
#9
James B Dewey, Brian E Applegate, John S Oghalai
Mammalian hearing sensitivity and frequency selectivity depend on a mechanical amplification process mediated by outer hair cells (OHCs). OHCs are situated within the organ of Corti atop the basilar membrane (BM), which supports sound-evoked traveling waves. It is well established that OHCs generate force to selectively amplify BM traveling waves where they peak, and that amplification accumulates from one location to the next over this narrow cochlear region. However, recent measurements demonstrate that traveling waves along the apical surface of the organ of Corti - the reticular lamina (RL) - are amplified over a much broader region...
January 16, 2019: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://read.qxmd.com/read/30646763/influence-of-subcortical-auditory-processing-and-cognitive-measures-on-cocktail-party-listening-in-younger-and-older-adults
#10
Chandni Jain, Vikas Mysore Dwarakanath, Amritha G
OBJECTIVE: The study aimed to investigate the influence of subcortical auditory processing and cognitive measures on cocktail party listening in younger and older adults with normal hearing sensitivity. DESIGN: Tests administered included quick speech perception in noise test to assess cocktail party listening, speech auditory brainstem response to assess subcortical auditory processing and digit span, digit sequencing and spatial selective attention test to assess cognitive processing...
January 15, 2019: International Journal of Audiology
https://read.qxmd.com/read/30629627/the-mandarin-spoken-word-picture-identification-test-in-noise-adaptive-mapid-a-measures-subtle-speech-recognition-in-noise-changes-and-spatial-release-from-masking-in-very-young-children
#11
Kevin Chi Pun Yuen, Xin Yue Qiu, Hong Yu Mou, Xin Xi
BACKGROUND: Spatial release of masking (SRM) is a measure of an individual's ability to perform speech-noise segregation, which is usually quantified by the extent of improvement of the individual's speech recognition performance when the noise is switched from a spatially co-located position (e.g., speech and noise both presented from the front) to a spatially separated position (e.g., speech presented from the front and noise presented from the right side) with reference to the target speech...
2019: PloS One
https://read.qxmd.com/read/30627650/spontaneous-otoacoustic-emissions-in-tecta-y1870c-mice-reflect-changes-in-cochlear-amplification-and-how-it-is-controlled-by-the-tectorial-membrane
#12
Mary Ann Cheatham, Yingjie Zhou, Richard J Goodyear, Peter Dallos, Guy P Richardson
Spontaneous otoacoustic emissions (SOAEs) recorded from the ear canal in the absence of sound reflect cochlear amplification, an outer hair cell (OHC) process required for the extraordinary sensitivity and frequency selectivity of mammalian hearing. Although wild-type mice rarely emit, those with mutations that influence the tectorial membrane (TM) show an incidence of SOAEs similar to that in humans. In this report, we characterized mice with a missense mutation in Tecta, a gene required for the formation of the striated-sheet matrix within the core of the TM...
November 2018: ENeuro
https://read.qxmd.com/read/30627315/development-and-validation-of-portable-automated-rapid-testing-part-measures-for-auditory-research
#13
Frederick J Gallun, Aaron Seitz, David A Eddins, Michelle R Molis, Trevor Stavropoulos, Kasey M Jakien, Sean D Kampel, Anna C Diedesch, Eric C Hoover, Karen Bell, Pamela E Souza, Melissa Sherman, Lauren Calandruccio, Gretchen Xue, Nardine Taleb, Rene Sebena, Nirmal Srinivasan
The current state of consumer-grade electronics means that researchers, clinicians, students, and members of the general public across the globe can create high-quality auditory stimuli using tablet computers, built-in sound hardware, and calibrated consumer-grade headphones. Our laboratories have created a free application that supports this work: PART (Portable Automated Rapid Testing). PART has implemented a range of psychoacoustical tasks including: spatial release from speech-on-speech masking, binaural sensitivity, gap discrimination, temporal modulation, spectral modulation, and spectrotemporal modulation (STM)...
May 7, 2018: Proceedings of Meetings on Acoustics
https://read.qxmd.com/read/30623318/interaural-pitch-discrimination-range-effects-for-bilateral-and-single-sided-deafness-cochlear-implant-users
#14
Matthew J Goupell, Stefano Cosentino, Olga A Stakhovskaya, Joshua G W Bernstein
By allowing bilateral access to sound, bilateral cochlear implants (BI-CIs) or unilateral CIs for individuals with single-sided deafness (SSD; i.e., normal or near-normal hearing in one ear) can improve sound localization and speech understanding in noise. Spatial hearing in the horizontal plane is primarily conveyed by interaural time and level differences computed from neurons in the superior olivary complex that receive frequency-matched inputs. Because BI-CIs and SSD-CIs do not necessarily convey frequency-matched information, it is critical to understand how to align the inputs to CI users...
January 8, 2019: Journal of the Association for Research in Otolaryngology: JARO
https://read.qxmd.com/read/30601227/high-variability-sentence-recognition-in-long-term-cochlear-implant-users-associations-with-rapid-phonological-coding-and-executive-functioning
#15
Gretchen N L Smith, David B Pisoni, William G Kronenberger
OBJECTIVES: The objective of the present study was to determine whether long-term cochlear implant (CI) users would show greater variability in rapid phonological coding skills and greater reliance on slow-effortful compensatory executive functioning (EF) skills than normal-hearing (NH) peers on perceptually challenging high-variability sentence recognition tasks. We tested the following three hypotheses: First, CI users would show lower scores on sentence recognition tests involving high speaker and dialect variability than NH controls, even after adjusting for poorer sentence recognition performance by CI users on a conventional low-variability sentence recognition test...
December 31, 2018: Ear and Hearing
https://read.qxmd.com/read/30599688/influence-of-discretization-error-on-instability-of-cochlear-model
#16
Yasuki Murakami
The instability derived from the cochlear model is a phenomenon used to characterize its active processing, which is one of the fundamentals of hearing. This processing relates to the activities of outer hair cells (OHCs) lining in the cochlea. The decline of this processing function is accounted for by the spatially irregular activities of OHCs. Current cochlear models show excessive instability when cochlea containing the irregular activity of the OHCs is simulated. To explain this phenomenon, there are two possibilities...
December 2018: Journal of the Acoustical Society of America
https://read.qxmd.com/read/30599669/effect-of-improving-audibility-on-better-ear-glimpsing-using-non-linear-amplification
#17
Baljeet Rana, Jörg M Buchholz
Better-ear glimpsing (BEG) utilizes interaural level differences (ILDs) to improve speech intelligibility in noise. This spatial benefit is reduced in most hearing-impaired (HI) listeners due to their increased hearing loss at high frequencies. Even though this benefit can be improved by providing increased amplification, the improvement is limited by loudness discomfort. An alternative solution therefore extends ILDs to low frequencies, which has been shown to provide a substantial benefit from BEG. In contrast to previous studies, which only applied linear stimulus manipulations, wide dynamic range compression was applied here to improve the audibility of soft sounds while ensuring loudness comfort for loud sounds...
December 2018: Journal of the Acoustical Society of America
https://read.qxmd.com/read/30599653/directional-hearing-and-sound-source-localization-by-fishes
#18
Anthony D Hawkins, Arthur N Popper
Directional hearing may enable fishes to seek out prey, avoid predators, find mates, and detect important spatial cues. Early sound localization experiments gave negative results, and it was thought unlikely that fishes utilized the same direction-finding mechanisms as terrestrial vertebrates. However, fishes swim towards underwater sound sources, and some can discriminate between sounds from different directions and distances. The otolith organs of the inner ear detect the particle motion components of sound, acting as vector detectors through the presence of sensory hair cells with differing orientation...
December 2018: Journal of the Acoustical Society of America
https://read.qxmd.com/read/30581544/effects-of-directional-hearing-aid-settings-on-different-laboratory-measures-of-spatial-awareness-perception
#19
Micha Lundbeck, Giso Grimm, Volker Hohmann, Lars Bramsløw, Tobias Neher
Hearing loss can negatively influence the spatial hearing abilities of hearing-impaired listeners, not only in static but also in dynamic auditory environments. Therefore, ways of addressing these deficits with advanced hearing aid algorithms need to be investigated. In a previous study based on virtual acoustics and a computer simulation of different bilateral hearing aid fittings, we investigated auditory source movement detectability in older hearing- impaired (OHI) listeners. We found that two directional processing algorithms could substantially improve the detectability of left-right and near-far source movements in the presence of reverberation and multiple interfering sounds...
October 2, 2018: Audiology Research
https://read.qxmd.com/read/30558491/spatial-release-from-informational-masking-evidence-from-functional-near-infrared-spectroscopy
#20
Min Zhang, Yu-Lan Mary Ying, Antje Ihlefeld
Informational masking (IM) can greatly reduce speech intelligibility, but the neural mechanisms underlying IM are not understood. Binaural differences between target and masker can improve speech perception. In general, improvement in masked speech intelligibility due to provision of spatial cues is called spatial release from masking. Here, we focused on an aspect of spatial release from masking, specifically, the role of spatial attention. We hypothesized that in a situation with IM background sound (a) attention to speech recruits lateral frontal cortex (LFCx) and (b) LFCx activity varies with direction of spatial attention...
January 2018: Trends in Hearing
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