keyword
https://read.qxmd.com/read/26927816/pharmacodynamics-of-alacepril-in-healthy-cats
#21
JOURNAL ARTICLE
Keisuke Sugimoto, Yoko Fujii, Izumi Takubo, Toshinori Shiga, Hiroshi Sunahara, Takuma Aoki, Kensuke Orito
Objectives The aims of this study were to investigate the pharmacodynamics of alacepril and to determine the appropriate dose for clinical usage in cats. Methods Six experimental cats were used. Each cat received alacepril orally at a single dose of 1 mg/kg, 2 mg/kg and 3 mg/kg. Blood samples were collected before administration and at 2, 4, 6, 8, 12, 24, 36, 48 and 72 h after administration to measure serum angiotensin converting enzyme (ACE) activity. Systolic blood pressure was also measured at the same time point...
June 2017: Journal of Feline Medicine and Surgery
https://read.qxmd.com/read/25559715/physiological-parameters-in-the-blood-of-a-murine-stress-induced-depression-model-before-and-after-repeated-passive-exercise
#22
JOURNAL ARTICLE
Tae Kyung Kim, Jin Young Park, Pyung Lim Han
BACKGROUND: Animal models are necessary to study the mechanism underlying the effects of exercise on depression but an effective procedure for exercise treatment and exercise effects on physiological parameters in a specific depression model need to be characterized. METHODS: Physiological parameters including lactate, partial pressue of O₂ (pO₂) and CO₂ (pCO₂) saturated O₂ (sO₂), pH, HCO₃, total CO₂ (TCO₂), and base excess extracellular fluid (BEecf) levels in the blood were measured after treatment with passive exercise in normal mice and a stress-induced depression model...
September 2015: Endocrinology and Metabolism
https://read.qxmd.com/read/23777282/reproducibility-of-pulse-wave-analysis-and-pulse-wave-velocity-in-patients-with-type-2-diabetes
#23
JOURNAL ARTICLE
Esben Laugesen, Niklas B Rossen, Pernille Høyem, Jens S Christiansen, Søren T Knudsen, Klavs W Hansen, Troels K Hansen, Per L Poulsen
AIMS: Patients with type 2 diabetes have increased arterial stiffness and a high incidence of cardiovascular disease compared with non-diabetics. Arterial stiffness and central waveforms can be assessed by carotid-femoral pulse wave velocity (PWV) and pulse wave analysis (PWA) using the SphygmoCor device. These methods can potentially improve cardiovascular risk stratification in the future. However, a prerequisite is acceptable reproducibility. The objective of this study was to assess the intra- and inter-observer reproducibility of PWV and PWA indices in patients with type 2 diabetes using the SphygmoCor device...
August 2013: Scandinavian Journal of Clinical and Laboratory Investigation
https://read.qxmd.com/read/22515427/the-effect-of-negative-wound-pressure-therapy-on-haemodynamics-in-a-laparostomy-wound-model
#24
COMPARATIVE STUDY
Sandra Lindstedt, Johan Hansson, Joanna Hlebowicz
We have recently shown that negative pressure wound therapy (NPWT) induces a decrease in microvascular blood flow in the small intestinal loop close to the dressing. The effect of NPWT is thus thought to be local. In this study, we investigate whether the application of NPWT in laparostomy affects the haemodynamics. Midline incisions were made in six pigs followed by NPWT at -120 mmHg for 20 minutes. The cardiac output, mean systemic arterial pressure, mean pulmonary artery pressu re, central venous pressure, left atrial pressure and superior mesenteric artery blood flow were recorded...
June 2013: International Wound Journal
https://read.qxmd.com/read/11240875/use-of-impedance-cardiography-to-monitor-haemodynamic-changes-during-laparoscopy-in-children
#25
JOURNAL ARTICLE
A Kardos, G Vereczkey, L Pirót, P Nyirády, R Mekler
METHODS: Haemodynamic changes were measured noninvasively using impedance cardiography (ICG) in 30 ASA I children during laparoscopic varicocelectomy under general anaesthesia. After induction and intubation, mechanical ventilation was started, then pneumoperitoneum (PP) was created. During the course of anaesthesia, values of endtidal CO2 pressue (PECO2), peak inspiratory airway pressure (PIP), heart rate (HR), mean arterial blood pressure (MABP), stroke volume index (SVI), cardiac index (CI) and systemic vascular resistance index (SVRI) were recorded at 1 min intervals...
March 2001: Paediatric Anaesthesia
https://read.qxmd.com/read/7355741/hypertension-and-propranolol-therapy-effect-on-blood-pressure-plasma-catecholamines-and-platelet-aggregation
#26
JOURNAL ARTICLE
N D Vlachakis, L Aledort
The effects of propranolol on blood pressure, plasma catecholamine concentration and platelet aggregation were examined in 16 patients with uncomplicated primary hypertension. The patients were studied at rest, during isometric handrip stress and 48 hours after sudden discontinuation of propranolol therapy. Plasma catecholamine concentration and platelet aggregation studies were also carried out in 11 age-matched normotensive and healthy subjects at rest. Plasma catecholamine concentration and platelet aggregation were greater in the hypertensive than in the normotensive subjects, but the difference reached statistical significance for aggregation only...
February 1980: American Journal of Cardiology
https://read.qxmd.com/read/4436732/a-study-of-the-long-term-effects-of-pre-eclampsia-on-blood-pressue-and-renal-function
#27
JOURNAL ARTICLE
M M Singh, I Macgillivray, R G Mahaffy
No abstract text is available yet for this article.
November 1974: Journal of Obstetrics and Gynaecology of the British Commonwealth
https://read.qxmd.com/read/1198810/-state-of-hemodynamics-and-external-respiration-during-peridural-anesthesia
#28
JOURNAL ARTICLE
A A Konopliankin
The author reports the results of hemoynamic, spirographic and biochemical studies conducted in patients, operated upon on the organs of the lower abdomen, pelvis and lower extremities. Arterial pressure and pulse rate were studied in 165 patients, venous pressue--in 50, spirographic studies--in 50, blood alkaline reserve--in 42.
September 1975: Vestnik Khirurgii Imeni I. I. Grekova
https://read.qxmd.com/read/1168335/quantitative-aspects-of-autoregulation-in-the-canine-kidney
#29
JOURNAL ARTICLE
P Bálint, E Tarján, J Juszkó
Autoregulatory changes in series connected vascular resistances were studied in the normal canine kidney. Two sets of observations were made: a) ureter pressure was increased by ureteral obstruction and b) arterial pressure was decreased by aortic clamping. It was assumed that in both experimental panels the decrement in intrarenal resistance is solely due to dilatation of the preglomerular vessels. Proximal tubular pressure is thought to equal deep venous (wedged) pressure under free flow and ureteral pressure under stop flow conditions...
1975: Pflügers Archiv: European Journal of Physiology
https://read.qxmd.com/read/1168334/the-central-arterial-pulses-experiments-on-a-hybrid-model-of-the-heart-and-the-arterial-system
#30
JOURNAL ARTICLE
T Kenner
In order to examine the contours of central aortic and coronary flow pulses as well as those of pressure and flow pulses along the aorta, a hybrid model of the arterial system and the heart was designed. The digitally programmed model of the aortic system is an inhomogeneous transmission line with adjustable reflection factors at the end and at three intermediate locations. For the reflection factor at the entrance different values may be chosen for the ejection time and the diastole. The influence of a stenosis and of frequency-independent damping may be examined...
1975: Pflügers Archiv: European Journal of Physiology
https://read.qxmd.com/read/979066/the-effect-of-saralasin-1sar-8-ala-angiotensin-ii-on-blood-pressure-in-patients-with-cushing-s-syndrome
#31
JOURNAL ARTICLE
W Vetter, H Vetter, R Beckerhoff, B Redlich, P Cottier, W Siegenthaler
To investigate the role of the renin angiotensin system in the pathogenesis of hypertension in Cushing's syndrome two patients with hypercorticism were infused with 20 mg saralasin (1-sar-8-ala-angiotensin II) over a period of 30 minutes under constant blood pressue control. In addition, one patient with primary aldosteronism, an established form of mineralocorticoid hypertension, served as control. Neither in the two patients with Cushing's syndrome nor in the patient with primary aldosteronism could a blood pressure lowering effect of saralasin be observed...
July 15, 1976: Klinische Wochenschrift
https://read.qxmd.com/read/959132/-effects-of-dextran-gelatine-and-homologous-plasma-on-circulation-in-shock-caused-by-severe-anemia-in-the-dog
#32
JOURNAL ARTICLE
W Dietze, P Rentrop, H D Schmidt, J Schmier
Irreversible shock is produced in 28 anaesthetized mongrel dogs by withdrawal of erythrocytes and substitution by dextran, gelatine or plasma to an average Hb of 4.5g%. In contrast to other shock models cardiac output and perfusion pressure are not decreased by this preparation. In order to maintain arterial blood pressue above 90 mm Hg significantly more gelatine than dextran or serum has to be infused. There is no difference in hemodynamic responses after treatment with dextran or gelatine respectively. Both groups treated with colloidal solutions have the same survival rate of 38%...
April 1976: Praktische Anästhesie, Wiederbelebung und Intensivtherapie
https://read.qxmd.com/read/936815/-influence-of-hypertension-in-the-2nd-half-of-pregnancy-on-the-fate-of-the-fetus-and-newborn-infant-with-reference-to-mean-pressure-using-wezler-b%C3%A3-ger-s-method
#33
JOURNAL ARTICLE
V Stranz
It is demonstrated retrospective calculation of mean arterial pressure (method of Wezler-Böger) in 1086 cases of hypertensive toxemia in pregnancy from the year 1966 to 1972 of the Department of Obstetrics and Gynecology University Rostock and Department of Obstetrics and Gynecology, Country Hospital Rostock. The grading of the values of mean arterial pressue in 3 groups shows an increasing of fetal retardation and increasing of perinatal mortality due to increasing of mean arterial pressue. This procedure allows a more different prognostic prediction of fetal outcome, than the separate systolic and diastolic blood pressure measurements...
1976: Zentralblatt Für Gynäkologie
https://read.qxmd.com/read/892103/-hemodynamics-during-combined-nociceptive-stimulation-and-stimulation-of-the-amygdaloid-complex-following-treatment-of-the-sensomotor-cortex
#34
JOURNAL ARTICLE
L S Isakova, G E Danilov
In acute experiments on cats, changes of the arterial pressue (AP), intracardiac pressure (ICP), and of the blood flow rate following a nociceptive stimulus (NS), electrical stimulation of the lateral nucleus of amygdala (AL), and the combination of these stimuli before and after application of strychnine and potassium chloride on sensorimotor cortical area, were studied. After the application of strychnine and potassium chloride, the stimulation of AL produced weaker pressor reaction; while a nociceptive stimulus was followed by the same changes as in the intact cats...
July 1977: Fiziologicheskiĭ Zhurnal SSSR Imeni I. M. Sechenova
https://read.qxmd.com/read/892101/-mechanism-of-formation-of-the-rheoophthalmogram-and-electroplethysmogram-of-the-eye
#35
JOURNAL ARTICLE
A I Kolinko, B B Zelikson
In cats, the rheogram of a portion of the vascular tract was recorded during changes of the eye pressure due to brief increase or decrease of the central arterial pressue. Comparison of the recorded changes with the oscillations of electrical conductivity suggest that the latter reflect primarily the changes of the blood linear speed during the time of one pulse cycle (at frequencies over 30 kHz). Slow changes of the electrical conductivity as recorded during electroplethysmography of the vascular tract, reflect primarily the changes of blood volume in the eye tunics...
July 1977: Fiziologicheskiĭ Zhurnal SSSR Imeni I. M. Sechenova
https://read.qxmd.com/read/877988/cow-s-urine-poisoning-in-nigeria-cardiorespiratory-effects-of-cow-s-urine-in-dogs
#36
JOURNAL ARTICLE
R A Elegbe, D D Oyebola
"Cow's urine" concoction (CUPR) is a traditional remedy for convulsive seizures in Nigeria. Its administration has been associated with severe poisoning, sometimes with a fatal outcome in Nigerian children. Recently, we showed that several of the components of the concoction are toxic. We have demonstrated in the present study certain cardio-respiratory effects of cow's urine concoction in dogs. On the cardiovascular system, an initial bradycardia followed by tachycardia and a biphasic effect on blood pressue characterized by a fall followed by a rise were demonstrated...
1977: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/870658/the-association-of-familial-liver-disease-subepidermal-immunoproteins-and-membranoproliferative-glomerulonephritis
#37
JOURNAL ARTICLE
R S Dobrin, J R Hoyer, T E Nevins, H Sharp, W C Gentry, R L Vernier
Herein we report a new familial form of hepatic disease. Each of the four patients had splenomegaly, hypersplenism, a small liver, biochemical evidence of hepatic excretory dysfunction and hepatocellular damage, kidneys without demonstrable cysts, and normal blood pressue. An evaluation of serum immunoproteins, autoantibodies, histocompatibility antigens, and mixed lymphocyte reactivity further defined the immunologic features of this syndrome. Extrahepatic manifestations included a papulosquamous dermatitis with deposition of immunoglobulins and complement in both normal and abnormal skin, a membranoproliferative glomerulonephritis with subendothelial deposits, arthritis, and pericardial, pleural, and synovial effusions...
June 1977: Journal of Pediatrics
https://read.qxmd.com/read/804910/role-of-sublingual-nitroglycerin-in-patients-with-acute-myocardial-infarction
#38
JOURNAL ARTICLE
C E Delgado, B Pitt, D R Taylor, M L Weisfeldt, D T Kelly
Fourteen patients with acute myocardial infarction were given 0.3 mg sublingual nitroglycerin within the first 12 hours of their acute myocardial infarction. Five minutes after sublingual nitroglycerin mean arterial pressure fell 9 mmHg (1.2 kPa) and remained significantly reduced for 30 minutes. Pulmonary capillary wedge pressure fell from a mean control value of 17 to 12 mmHg (2.3 to 1.6 kPa) and also remained reduced for 30 minutes. Heart rate was significantly raised and stroke work index reduced at five minutes...
April 1975: British Heart Journal
https://read.qxmd.com/read/493787/-rare-etiology-of-hemiplegia-with-young-adult-paradoxical-embolism-author-s-transl
#39
JOURNAL ARTICLE
J Goasguen, C Ribot, F Le Gall, J P Girard, J Duret, J C Piette
Paradoxical embolism is due to the passage of an embolic material from the deep veins of the lower extremities or pelvis, into the systemic circulation through an abnormal intracardiac communication. Only the angiographic and hemodynamic diagnosis practised on two young patients with a cerebral embolism, can explain the mechanism. The diagnosis is based on the arterial embolism, the venous thrombosis with or without pulmonary embolism, the abnormal communication favoring right-to-left shunting. The rising of right atrial pressures permits this shunting...
March 1979: Revue Neurologique
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