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Gérôme Lombardo, Kaoutar Hafraoui, Yves Beguin, Gaëlle Vertenoeil
Polycythemia is suspected when hemoglobin and/or hematocrit levels exceed established norms based on gender and age. This biological anomaly can arise from a myeloproliferative neoplasm known as polycythemia vera, or be secondary to excess erythropoietin (EPO) or decreased in plasma volume. Faced with polycythemia, the search for JAK2 mutations and measurement of serum EPO levels can guide toward the etiology. In polycythemia vera, thromboembolic events are the most lethal complications and unfortunately often the initial manifestation of the disease...
February 2024: Revue Médicale de Liège
#2
JOURNAL ARTICLE
M Rodríguez-Prieto, F Modino-García, C de la Arada-Benavides, R de la Puente, A Carvajal, I Rodríguez-Cabañeros, C de Prado-Santos, B de Mota-Luna, T Fernández-Villa, J P Fernández-Váquez, V Martín
OBJECTIVE: The aim of our research was to compare the evolution of the immune response induced by the BNT162b2 vaccine after the administration of two and three doses in healthcare personnel and in institutionalized elderly people (>65 years of age) without previous SARS-CoV-2 infection. MATERIAL AND METHODS: A prospective observational study was carried out on a convenience sample made up of health workers and institutionalized elderly people, measuring antibodies against S and N proteins of SARS-CoV-2 two and six months after receiving the second vaccine dose, as well as two months after receiving the third dose...
October 11, 2023: Semergen
#3
Seyed A Khalafi, Alan De La Rosa Vaquez, Fatma Dihowm
Escherichia (E.) coli pneumonia is a rare infection commonly presenting with a cavitary lesion. We report a case of a 44-year-old Hispanic male with comorbidities who was admitted to our facility with multiple falls for two days, shortness of breath, continuous diarrhea, and urinary urgency. Lab results showed leukocytosis with neutrophil predominance, anemia, and respiratory alkalosis. The patient was also noted to have uncontrolled diabetes mellitus with an A1c of 17.6%. Prior to admission to the medical intensive care unit (MICU), the patient was administered vancomycin and cefepime...
February 2023: Curēus
#4
JOURNAL ARTICLE
Jaime Quintana Benito, Antonio A Fernández-Balbuena, Juan Carlos Martínez-Antón, Daniel Váquez Molini
Nowadays, fog is still a natural phenomenon that hinders our ability to detect targets, particularly in the field of driving where accidents are increasing. In the literature we find different studies determining the range of visibility, improving the quality of an image, determining the characteristics of fog, etc. In this work we propose the possibility of using a structured lighting system, on which we project the light towards the target, limiting the field lighting. We have developed a scattering light propagation model to simulate and subsequently study the veil luminance, generated by backscattering, to predict the decrease in visibility...
November 2022: Heliyon
#5
Axel Cailleteau, Komivi Agbetsivi, Valentine Guimas, Stéphane Supiot, Luc Ollivier
Extramedullary hematopoiesis (EMH) is a rare cause of spinal cord compression defined as finding hematopoietic elements outside the physiological location in the bone marrow. We report the case of a 70-year-old man with JAK 2 positive myeloproliferative syndrome type polycythemia vera (PV), initially treated with hydroxyurea. Two years after diagnosis, he presented progression with biological and clinical evolution associating hyperleukocytosis and hepatosplenomegaly with no evidence of acute myeloid leukemia...
January 2023: Clinical and Translational Radiation Oncology
#6
Sean R McWhinney, Katharina Brosch, Vince D Calhoun, Benedicto Crespo-Facorro, Nicolas A Crossley, Udo Dannlowski, Erin Dickie, Lorielle M F Dietze, Gary Donohoe, Stefan Du Plessis, Stefan Ehrlich, Robin Emsley, Petra Furstova, David C Glahn, Alfonso Gonzalez-Valderrama, Dominik Grotegerd, Laurena Holleran, Tilo T J Kircher, Pavel Knytl, Marian Kolenic, Rebekka Lencer, Igor Nenadić, Nils Opel, Julia-Katharina Pfarr, Amanda L Rodrigue, Kelly Rootes-Murdy, Alex J Ross, Kang Sim, Antonín Škoch, Filip Spaniel, Frederike Stein, Patrik Švancer, Diana Tordesillas-Gutiérrez, Juan Undurraga, Javier Váquez-Bourgon, Aristotle Voineskos, Esther Walton, Thomas W Weickert, Cynthia Shannon Weickert, Paul M Thompson, Theo G M van Erp, Jessica A Turner, Tomas Hajek
No abstract text is available yet for this article.
July 20, 2022: Molecular Psychiatry
#7
JOURNAL ARTICLE
Sean R McWhinney, Katharina Brosch, Vince D Calhoun, Benedicto Crespo-Facorro, Nicolas A Crossley, Udo Dannlowski, Erin Dickie, Lorielle M F Dietze, Gary Donohoe, Stefan Du Plessis, Stefan Ehrlich, Robin Emsley, Petra Furstova, David C Glahn, Alfonso Gonzalez-Valderrama, Dominik Grotegerd, Laurena Holleran, Tilo T J Kircher, Pavel Knytl, Marian Kolenic, Rebekka Lencer, Igor Nenadić, Nils Opel, Julia-Katharina Pfarr, Amanda L Rodrigue, Kelly Rootes-Murdy, Alex J Ross, Kang Sim, Antonín Škoch, Filip Spaniel, Frederike Stein, Patrik Švancer, Diana Tordesillas-Gutiérrez, Juan Undurraga, Javier Váquez-Bourgon, Aristotle Voineskos, Esther Walton, Thomas W Weickert, Cynthia Shannon Weickert, Paul M Thompson, Theo G M van Erp, Jessica A Turner, Tomas Hajek
Schizophrenia is frequently associated with obesity, which is linked with neurostructural alterations. Yet, we do not understand how the brain correlates of obesity map onto the brain changes in schizophrenia. We obtained MRI-derived brain cortical and subcortical measures and body mass index (BMI) from 1260 individuals with schizophrenia and 1761 controls from 12 independent research sites within the ENIGMA-Schizophrenia Working Group. We jointly modeled the statistical effects of schizophrenia and BMI using mixed effects...
June 14, 2022: Molecular Psychiatry
#8
JOURNAL ARTICLE
B Alami, S Boujraf, L Quenum, A Oudrhiri, M Y Alaoui Lamrani, M Haloua, M Boubbou, M Maâroufi
UNLABELLED: The work's purpose is to make a general review on the various clinical-radiological aspects and the management of cerebral venous thrombosis (CVT) in our hospital and compare them to those described in the literature. MATERIAL AND METHOD: Our series included 62 patients aged over 18 years, collected over 7 years (2009-2016) in the radiology department of the CHU Hassan II of Fez (Morocco), in which the radiological diagnosis of TVC was retained. Our patients have benefited from a brain CT scan and brain MRI...
December 2019: Journal de Médecine Vasculaire
#9
JOURNAL ARTICLE
Néstor J Martínez-Hernández, Fernando Sánchez-García, Alejandro Váquez-Sánchez, José M Galbis-Caravajal
We communicate the first reported application of video-assisted thoracic surgery for early repair of a postintubation tracheal laceration. The patient was a 60-year-old man. After an initial unsuccessful approach with conservative measures, surgical repair was indicated. The patient underwent 2-port video-assisted thoracic surgery for direct tracheal repair using a 3-0 resorbable monofilament running suture and two reinforcing X-stitches. Bronchoscopic control after 2 and 4 weeks showed complete restoration of the airway, with no complication...
July 2019: Annals of Thoracic Surgery
#10
REVIEW
Daniela Rodrigues-Amorim, Tania Rivera-Baltanás, Benito Regueiro, Carlos Spuch, María Elena de Las Heras, Raul Vázquez-Noguerol Méndez, Maria Nieto-Araujo, Carolina Barreiro-Villar, Jose Manuel Olivares, Roberto Carlos Agís-Balboa
OBJECTIVES: Schizophrenia is a poorly understood chronic disease. Its pathophysiology is complex, dynamic, and linked to epigenetic mechanisms and microbiota involvement. Nowadays, correlating schizophrenia with the environment makes sense owing to its multidimensional implications: temporal and spatial variability. Microbiota involvement and epigenetic mechanisms are factors that are currently being considered to better understand another dimension of schizophrenia. METHODS: This review summarises and discusses currently available information, focussing on the microbiota, epigenetic mechanisms, technological approaches aimed at performing exhaustive analyses of the microbiota, and psychotherapies, to establish future perspectives...
December 2018: World Journal of Biological Psychiatry
#11
REVIEW
Historical evolution of ideas on eclampsia/preeclampsia: A proposed optimistic view of preeclampsia.
Pierre-Yves Robillard, Gustaaf Dekker, Gérard Chaouat, Marco Scioscia, Silvia Iacobelli, Thomas C Hulsey
Eclampsia (together with epilepsy) being the first disease ever written down since the beginning of writings in mankind 5000 years ago, we will make a brief presentation of the different major steps in comprehension of Pre-eclampsia. 1) 1840. Rayer, description of proteinuria in eclampsia, 2) 1897 Vaquez, discovery of gestational hypertension in eclamptic women, 3) In the 1970's, description of the "double" trophoblastic invasion existing only in humans (Brosens & Pijnenborg,), 4) between the 1970's and the 1990's, description of preeclampsia being a couple disease...
September 2017: Journal of Reproductive Immunology
#12
LETTER
Inès Masmoudi, Valérie Gras-Champel, Dominique Barbieux-Vaquez, Kamel Masmoudi
No abstract text is available yet for this article.
June 2017: Thérapie
#13
REVIEW
Sabine Blum, Filipe Martins, Lorenzo Alberio
The discovery of JAK2 V617F mutation in the mid-2000s started to fill the gap between clinical presentation of polycythemia vera (PV), first described by Vaquez at the end of the 19th century, and spontaneous erythroid colony formation, reported by Prchal and Axelrad in the mid-1970s. The knowledge on this mutation brought an important insight to our understanding of PV pathogenesis and led to a revision of the World Health Organization diagnostic criteria in 2008. JAK-STAT is a major signaling pathway implicated in survival and proliferation of hematopoietic precursors...
2016: Journal of Blood Medicine
#14
JOURNAL ARTICLE
Jeanette M Smith
No abstract text is available yet for this article.
January 19, 2016: JAMA
#15
JOURNAL ARTICLE
Tuhina Neogi, Tim L Th A Jansen, Nicola Dalbeth, Jaap Fransen, H Ralph Schumacher, Dianne Berendsen, Melanie Brown, Hyon Choi, N Lawrence Edwards, Hein J E M Janssens, Frédéric Lioté, Raymond P Naden, George Nuki, Alexis Ogdie, Fernando Perez-Ruiz, Kenneth Saag, Jasvinder A Singh, John S Sundy, Anne-Kathrin Tausche, Janitzia Vaquez-Mellado, Steven A Yarows, William J Taylor
OBJECTIVE: Existing criteria for the classification of gout have suboptimal sensitivity and/or specificity, and were developed at a time when advanced imaging was not available. The current effort was undertaken to develop new classification criteria for gout. METHODS: An international group of investigators, supported by the American College of Rheumatology and the European League Against Rheumatism, conducted a systematic review of the literature on advanced imaging of gout, a diagnostic study in which the presence of monosodium urate monohydrate (MSU) crystals in synovial fluid or tophus was the gold standard, a ranking exercise of paper patient cases, and a multi-criterion decision analysis exercise...
October 2015: Annals of the Rheumatic Diseases
#16
JOURNAL ARTICLE
Tuhina Neogi, Tim L Th A Jansen, Nicola Dalbeth, Jaap Fransen, H Ralph Schumacher, Dianne Berendsen, Melanie Brown, Hyon Choi, N Lawrence Edwards, Hein J E M Janssens, Frédéric Lioté, Raymond P Naden, George Nuki, Alexis Ogdie, Fernando Perez-Ruiz, Kenneth Saag, Jasvinder A Singh, John S Sundy, Anne-Kathrin Tausche, Janitzia Vazquez-Mellado, Steven A Yarows, William J Taylor
OBJECTIVE: Existing criteria for the classification of gout have suboptimal sensitivity and/or specificity, and were developed at a time when advanced imaging was not available. The current effort was undertaken to develop new classification criteria for gout. METHODS: An international group of investigators, supported by the American College of Rheumatology and the European League Against Rheumatism, conducted a systematic review of the literature on advanced imaging of gout, a diagnostic study in which the presence of monosodium urate monohydrate (MSU) crystals in synovial fluid or tophus was the gold standard, a ranking exercise of paper patient cases, and a multicriterion decision analysis exercise...
October 2015: Arthritis & Rheumatology
#17
REVIEW
Rocío Campos del Portillo, Samara Palma MiIla, Natalia García Váquez, Bricia Plaza López, Laura Bermejo López, Pilar Riobó Serván, Pedro Pablo García-Luna, Carmen Gómez-Candela
Early identification of undernourished patients in the healthcare setting, and their nutritional treatment, are essential if the harmful effects of poor nourishment are to be avoided and care costs kept down. The aim of assessing nutritional status is to determine the general health of a patient from a nutritional viewpoint. All hospitalised patients should undergo nutritional screening within 24-48 h of admission, as should any patient who shows signs of being malnourished when visiting any healthcare centre...
February 26, 2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
#18
REVIEW
Hugo Peluffo, Ugutz Unzueta, María Luciana Negro-Demontel, Zhikun Xu, Esther Váquez, Neus Ferrer-Miralles, Antonio Villaverde
The increasing incidence of diseases affecting the central nervous system (CNS) demands the urgent development of efficient drugs. While many of these medicines are already available, the Blood Brain Barrier and to a lesser extent, the Blood Spinal Cord Barrier pose physical and biological limitations to their diffusion to reach target tissues. Therefore, efforts are needed not only to address drug development but specially to design suitable vehicles for delivery into the CNS through systemic administration...
March 2015: Biotechnology Advances
#19
JOURNAL ARTICLE
Maruxa Zapata-Cachafeiro, Cristian González-González, Juan M Váquez-Lago, Paula López-Vázquez, Ana López-Durán, Ernesto Smyth, Adolfo Figueiras
OBJECTIVES: Antibiotic resistance is a major public health concern and is greatly exacerbated by inappropriate antibiotic use at a community level. The aim of this study was to ascertain which attitudes of community pharmacists were related to inappropriate antibiotic dispensing. METHODS: We conducted a cross-sectional study of community pharmacists in a region situated in northern Spain (n = 393). Personal interviews were conducted using a self-administered questionnaire...
November 2014: Journal of Antimicrobial Chemotherapy
#20
JOURNAL ARTICLE
G Duclos, M Eté, C Bassez, M Gainnier, B Eon
We present the case of a 46-year-old patient without any past medical history, admitted to our ICU for cardiogenic shock complicating acute coronary syndrome. The blood tests found polycethemia, a polycethemia vera was suspected and confirmed by genetic analysis. Ischemic heart failure as an initial symptom of polycethemia vera and its treatment by arterial bleeding is a rare event that we describe in this article.
June 2014: Annales Françaises D'anesthèsie et de Rèanimation
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