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JOURNAL ARTICLE
Torsten Kucharzik, Axel Dignass
No abstract text is available yet for this article.
August 2023: Zeitschrift Für Gastroenterologie
#22
JOURNAL ARTICLE
Pia Lorenz, Axel Dignaß, Torsten Kucharzik, Nadine Fischer, Petra Lynen Jansen
No abstract text is available yet for this article.
August 2023: Zeitschrift Für Gastroenterologie
#23
JOURNAL ARTICLE
Alex Arenas, María José Moreta, Ingrid Ordás, Agnès Fernández Clotet, Berta Caballol, Marta Gallego, Alejandro Vara, Rebeca Barastegui, Angel Giner, Cristina Prieto, Maria Carme Masamunt, Roberto Candia, Elena Ricart
BACKGROUND AND OBJECTIVES: Combination therapy with an immunomodulator (IMM) and an anti-TNF is commonly recommended in Crohn's disease (CD) and ulcerative colitis (UC) patients. However, little is known about relapse rates after therapeutic de-escalation. This study aimed to evaluate the risk of relapse in a cohort of UC and CD patients with long-standing clinical remission after discontinuation of IMM or anti-TNF and to identify predictive factors for relapse. METHODS: This retrospective study included patients with UC or CD on combination therapy and clinical remission for at least 6 months...
August 8, 2023: Gastroenterología y Hepatología
#24
RANDOMIZED CONTROLLED TRIAL
Carme Loras, Pablo Ruiz-Ramirez, Juan Romero, Xavier Andújar, Josep Bargallo, Esther Bernardos, Marta Maia Boscá-Watts, Carlo Brugiotti, Eduard Brunet, David Busquets, Elena Cerrillo, Francisco Javier Cortina, Juan Antonio Díaz-Milanés, Carmen Dueñas, Ramón Farrés, Thomas Golda, Ferran González-Huix, Joan B Gornals, Jordi Guardiola, David Julià, Alba Lira, Jordina Llaó, Miriam Mañosa, Ingrid Marin, Mónica Millán, David Monfort, David Moro, Josep Mullerat, Mercè Navarro, Francisco Pérez Roldán, Eva Pijoan, Vicente Pons, José Reyes, María Rufas, Empar Sainz, Vicente Sanchiz, Anna Serracant, Eva Sese, Cristina Soto, Jose Troya, Natividad Zaragoza, Cristian Tebé, Marta Paraira, Emma Sudrià-Lopez, Vicenç Mayor, Fernando Fernández-Bañares, Maria Esteve
BACKGROUND: Stenosis is one of the most common complications in patients with Crohn's disease (CD). Endoscopic balloon dilation (EBD) is the treatment of choice for a short stenosis adjacent to the anastomosis from previous surgery. Self-expandable metal stents (SEMS) may be a suitable treatment option for longer stenoses. To date, however, there is no scientific evidence as to whether endoscopic (EBD/SEMS) or surgical treatment is the best approach for de novo or primary stenoses that are less than 10 cm in length...
June 27, 2023: Trials
#25
REVIEW
Daniela E Aust, Gustavo B Baretton, Ulrich Sommer
Ulcerative colitis (UC) is a chronic inflammatory bowel disease beginning in the rectum and gradually extending to the right-sided colon and the terminal ileum (backwash-ileitis). Its causes are still not completely understood. Genetic susceptibility, changes in the microbiota and immune response, as well as environmental factors are thought to influence the disease course.Patients with UC are at increased risk of developing colorectal cancer (CRC) when compared to an age-matched normal population. Cancer risk increases with early onset, duration, and extent of the disease, with development of strictures, intraepithelial neoplasia, and concomitant primary sclerosing cholangitis...
June 13, 2023: Pathologie (Heidelb)
#26
JOURNAL ARTICLE
C E Lombo-Moreno, O M Muñoz-Velandia, D G Fernández-Ávila, J E Barahona-Correa, V López-Ramírez, A Rodriguez-Varon
INTRODUCTION AND AIM: The majority of patients with inflammatory bowel disease (IBD) seek information about their disease on the Internet. The reliability, comprehensiveness, and quality of said information in Spanish has not previously been studied. MATERIALS AND METHODS: An analytic observational study was conducted that included YouTube® videos on IBD available in Spanish, describing general characteristics, engagement, and sources. Standard tools for evaluating reliability (DISCERN), comprehensiveness, and overall quality (Global Quality Score, GQS) were employed...
May 8, 2023: Revista de Gastroenterología de México
#27
Belén Martínez Benito, Javier P Gisbert, Lucio Jesús García Fraile Fraile, Ana Barrios Blandino, María Chaparro
No abstract text is available yet for this article.
May 5, 2023: Gastroenterología y Hepatología
#28
JOURNAL ARTICLE
Alicia González-Martínez, Inés Muro, Sonia Quintas, María Chaparro, Javier P Gisbert, Ancor Sanz-García, María José Casanova, Cristina Rubín de Célix, José Vivancos, Ana Beatriz Gago-Veiga
BACKGROUND: The gut-brain axis describes a complex bidirectional association between neurological and gastrointestinal (GI) disorders. In patients with migraine, GI comorbidities are common. We aimed to evaluate the presence of migraine among patients with inflammatory bowel disease (IBD) according to Migraine Screen-Questionnaire (MS-Q) and describe the headache characteristics compared to a control group. Additionally, we explored the relationship between migraine and IBD severities...
May 5, 2023: Gastroenterología y Hepatología
#29
JOURNAL ARTICLE
Juliane Weilandt, Vincent Hoffmann, Axel Zahn, Silja Guski, Michael Mroß, Wiebke K Peitsch
No abstract text is available yet for this article.
April 2023: Journal der Deutschen Dermatologischen Gesellschaft: JDDG
#30
JOURNAL ARTICLE
Domingo Balderramo, Jesús Yamamoto Furusho, Enrique Ponce de León, Julio de María, Ignacio Zubiaurre, Silvia Pedreira, Camilo Lis, Laura Brion, Juan A De Paula
OBJECTIVE: Data on anti-tumor necrosis factor (anti-TNF) treatment and suboptimal response (SOR) among patients with inflammatory bowel diseases (IBD) in Latin America (LATAM) are scarce. This study evaluated the incidence and indicators of SOR to anti-TNF therapy in patients with ulcerative colitis (UC) and Crohn´s disease (CD) from Argentina, Colombia and Mexico. PATIENTS AND METHODS: We performed retrospective analysis of data from LATAM patients of the EXPLORE study (NCT03090139) including adult patients with IBD who initiated anti-TNF therapy between 03-2010 to 03-2015...
April 14, 2023: Gastroenterología y Hepatología
#31
REVIEW
Leishmania infection in patients with Inflammatory Bowel Disease: case series and literature review.
Leticia Gimeno Pitarch, Pedro Almela, Pilar Nos
Infection by Leishmania spp. in patients diagnosed with Inflammatory Bowel Disease (IBD) is rare. Considered endemic in the Mediterranean basin, its manifestations are almost exclusive of patients with impaired cellular immunity. Most of the evidence is found through case reports; without guidelines for its management in patients with IBD. In this study we present three cases of Leishmania infection in patients with IBD that lead us to carry out a review of the current literature. Immunosuppressive treatment contributes to this infection, which presents atypically, with a challenging diagnosis...
April 13, 2023: Gastroenterología y Hepatología
#32
JOURNAL ARTICLE
Miquel Sans Cuffi, Federico Argüelles Arias, Ana Echarri Piudo, Daniel Ginard Vicens, Ana Gutiérrez Casbas, Ignacio Marín-Jiménez
BACKGROUND AND OBJECTIVE: Ulcerative colitis (UC) clinical guidelines include the best available evidence, although not all clinical situations are answered, so their management can be controversial. The aim of this study is to identify the situations of mild to moderate UC susceptible to controversy and to evaluate the degree of agreement or disagreement with specific proposals. METHODS: Inflammatory bowel disease (IBD) expert discussion meetings were used to identify criteria, attitudes and opinions regarding the management of UC...
February 15, 2023: Gastroenterología y Hepatología
#33
JOURNAL ARTICLE
Magdolna Ozsvári-Vidákovich, Zoltán Péter, Fruzsina Vilmos, Attila Szijártó, Ádám Dániel, Lóránd Lakatos, Nándor Ács, Levente Sára, Szilvia Szakony, István Sziller
In women, primary sclerotising cholangitis (PSC) associated with ulcerative colitis and intrahepatic cholestasis is a rare disease. To date, there are no data from Hungary on the fertility and pregnancy outcome of women with this chronic liver disease. Our aim is to present the favorable pregnancy outcome of a woman with PSC associated with ulcerative colitis, intrahepatic cholestasis and postpartum colectomy, and review of the literature. A young nulligravida was first diagnosed with ulcerative colitis. Five years later, PSC developed with progressive fibrosis and cholestasis necessitating liver transplantation...
February 12, 2023: Orvosi Hetilap
#34
Claudia Fuxman, Beatriz Sicilia, María Eugenia Linares, Santiago García-López, Ramiro González Sueyro, Yago González-Lamac, Yamile Zabana, Joaquín Hinojosa, Manuel Barreiro-de Acosta, Domingo Balderramo, Deborah Balfour, Maricel Bellicoso, Pamela Daffra, Daniela Morelli, Marina Orsi, Astrid Rausch, Orlando Ruffinengo, Martín Toro, Alicia Sambuelli, Abel Novillo, Fernando Gomollón, Juan Andrés De Paula
INTRODUCTION: Ulcerative colitis (UC) is a chronic inflammatory disease that compromises the colon, affecting the quality of life of individuals of any age. In practice, there is a wide spectrum of clinical situations. The advances made in the physio pathogenesis of UC have allowed the development of new, more effective and safer therapeutic agents. OBJECTIVES: To update and expand the evaluation of the efficacy and safety of relevant treatments for remission induction and maintenance after a mild, moderate or severe flare of UC...
March 2023: Gastroenterología y Hepatología
#35
JOURNAL ARTICLE
Marta Kantauskaite, Günter Fürst, Peter Minko, Gerald Antoch, Lars Christian Rump, Sebastian A Potthoff
The present case report focuses on a rare presentation of aortic coarctation. A 38-year-old man with well-controlled arterial hypertension, minimal change glomerulonephritis and colitis ulcerosa was suffering from recurrent acute renal failure episodes during viral gastroenteritis. No other symptoms at rest or during physical activity were present. The workup included renal duplex sonography, which unmasked tardus parvus profile in both kidneys without any acceleration of blood flow in the renal arteries. Further examination included CT angiography, which confirmed the diagnosis of aortic coarctation...
January 13, 2023: Journal of Hypertension
#36
JOURNAL ARTICLE
A Jena, N Grover, P Bhatia, M Singh, D Lad, K K Prasad, H Singh, U Dutta, V Sharma
INTRODUCTION AND AIM: Thiopurine-related leukopenia is associated with polymorphisms in the thiopurine methyltransferase (TPMT) and nucleoside diphosphate-linked moiety X type motif 15 (NUDT15) genes. However, those polymorphisms explain only a fraction of thiopurine-related leukopenia. Our aim was to study the role of an inosine triphosphate pyrophosphatase (ITPA) polymorphism in patients with inflammatory bowel disease (IBD) and thiopurine-related leukopenia that was unexplained by the TPMT and NUDT15 polymorphisms...
January 25, 2023: Revista de Gastroenterología de México
#37
JOURNAL ARTICLE
Mario García-Alanis, Liz Toapanta-Yanchapaxi, Arturo Reyes-Velásquez, Fernando Mancilla, Isela Pérez-Mayo, Jesús K Yamamoto-Furusho
OBJECTIVE: To determine if anxiety and depression are associated with a lower QoL in patients with UC in remission. PATIENTS AND METHODS: We included consecutive patients with a previously confirmed diagnosis of UC in remission for at least 12 months and who answered complete questionnaires: IBDQ-32, HAD. Clinical and sociodemographic characteristics were obtained. We performed non-parametric tests, and correlations between HADS and IBDQ-32 were analyzed using Spearman's correlation coefficient (r)...
January 20, 2023: Gastroenterología y Hepatología
#38
JOURNAL ARTICLE
Andrea Warpakowski
No abstract text is available yet for this article.
January 2023: MMW Fortschritte der Medizin
#39
JOURNAL ARTICLE
Ignacio Aguirre-Allende, Jose M Enríquez-Navascués, Garazi Elorza, Ane Etxart, Ainhoa Echeveste, Nerea Borda-Arrizabalaga, Carlos Placer, Yolanda Saralegui
AIM: To analyze the surgical burden of UC care in the last two decades, analyzing the characteristics of the patients, surgical indications along with the short and long-term results. METHOD: Single-center retrospective cohort analysis of UC patients undergoing abdominal and anorectal surgery between January 2000 and December 2020. The care burden, clinical data and results were analyzed according to distribution by decades. RESULTS: 128 patients, 37% female, underwent 376 surgical interventions (296 intestinal procedures and 80 anorectal)...
January 2023: Cirugia española
#40
RANDOMIZED CONTROLLED TRIAL
Jon D Vogel, Phillip R Fleshner, Stefan D Holubar, Vitaliy Y Poylin, Scott E Regenbogen, Brandon C Chapman, Evangelos Messaris, Matthew G Mutch, Neil H Hyman
BACKGROUND: In patients with ulcerative colitis who undergo IPAA, a diverting ileostomy is used to diminish the severity of anastomotic complications. Typically, the ileostomy is closed after an interval of 2 to 4 months. The safety of earlier closure of the ileostomy after pouch surgery is unknown. OBJECTIVE: This study aimed to compare postoperative outcomes in patients randomly assigned to early (7-12 days) or late (≥8 weeks) ileostomy closure after ileal pouch construction...
February 1, 2023: Diseases of the Colon and Rectum
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