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Garan Jones, Luke C Pilling, Chia-Ling Kuo, George Kuchel, Luigi Ferrucci, David Melzer
BACKGROUND: Aging is characterized by chronic inflammation plus muscle mass and strength loss, termed sarcopenia. Human Leukocyte Antigen (HLA) types are drivers of autoimmune disease, although with limited penetrance. We tested whether autoimmune diagnoses are associated with sarcopenia, and whether HLA types and related genetic variants associate with sarcopenia in autoimmune disease free older people. METHODS: Data from 181,301 UK Biobank European descent volunteers aged 60 - 70 with measured hand-grip strength and impedance...
February 17, 2019: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
M Del Papa, G D'Amata, F Manzi, P Carnì, G Florio, M Crovaro, L Musmeci, C Buonocore
Chronic pain and recurrence rates are the main challenge in modern inguinal hernia surgery. Several trials have investigated the role of self-adhesive mesh repair for inguinal hernia, with special attention to the incidence of chronic postoperative inguinal pain and recurrence. The purpose of our study was to retrospectively evaluate the early and long-term results using a self-gripping mesh (Parietex Progrip® , Covidien) in our institution. A total of 204 patients, mean age 50.3 standard deviation (SD) 15...
January 2019: Il Giornale di Chirurgia
L Mattar, N Farran, J Abi Kharma, N Zeeni
BACKGROUND: Extensive research has been conducted to investigate the effects of media violence on attitudes, behaviors, and cardiovascular health; however, only few studies have examined its effect on appetite, eating behavior and food preferences. Little attention has been given to understand how movie genre manipulates the physiology and the eating behavior of individuals. The present study aimed at investigating the acute effect of violence content in movies on appetite perception, heart rate and blood pressure, along with food preferences and intake in young individuals...
February 10, 2019: Eating Behaviors
Kinda Ibrahim, Fiona F A Howson, David J Culliford, Avan A Sayer, Helen C Roberts
BACKGROUND: Frailty and sarcopenia are common amongst hospitalised older people and associated with poor healthcare outcomes. Widely recognised tools for their identification are the Fried Frailty Phenotype, its self-report version the FRAIL Scale, and the European Working Group on Sarcopenia in Older People (EWGSOP) criteria. We studied the feasibility of using these tools in a hospital setting of acute wards for older people. METHODS: Patients aged 70+ years admitted to acute wards at one English hospital were prospectively recruited...
February 15, 2019: BMC Geriatrics
Wenjun Tan, Cunyi Shen, Yu Luo, Haoyang Zhu, Tao Ma, Dinghui Dong, Aihua Shi, Zhao Xue, Rongqian Wu, Y Lyu
A motion unit for sucking robot with a stable motion, convenient operation and process simulation is introduced. The key parameters and process data of the sucking operation were obtained from the clinical work, which provided the basis for the design of the sucking robot motion unit. According to the points of sucking action, robotic thumb, forefinger and metacarpophalangeal joints were used to grip the suction tube, and the servo and arm structure were used to simulate the motion of the wrist and elbow to complete the rotation and push of the sputum suction tube...
January 30, 2019: Zhongguo Yi Liao Qi Xie za Zhi, Chinese Journal of Medical Instrumentation
Marco Lanzilotto, Carolina Giulia Ferroni, Alessandro Livi, Marzio Gerbella, Monica Maranesi, Elena Borra, Lauretta Passarelli, Michela Gamberini, Leonardo Fogassi, Luca Bonini, Guy A Orban
Current knowledge regarding the processing of observed manipulative actions (OMAs) (e.g., grasping, dragging, or dropping) is limited to grasping and underlying neural circuitry remains controversial. Here, we addressed these issues by combining chronic neuronal recordings along the anteroposterior extent of monkeys' anterior intraparietal (AIP) area with tracer injections into the recorded sites. We found robust neural selectivity for 7 distinct OMAs, particularly in the posterior part of AIP (pAIP), where it was associated with motor coding of grip type and own-hand visual feedback...
February 15, 2019: Cerebral Cortex
Kevin J Zuo, Moaath Saggaf, Herbert P von Schroeder, Paul Binhammer
BACKGROUND: Tendon adhesions and capsular contractures following trauma to the proximal interphalangeal joint (PIPJ) may significantly reduce hand function. Traditional, staged surgical management prioritizes restoration of PIPJ passive range of motion with joint release prior to restoration of active range of motion (AROM) with tenolysis. This is expensive and burdensome for patients. Our objective was to evaluate functional outcomes of combined PIPJ release and zone II flexor tenolysis...
February 14, 2019: Hand: Official Journal of the American Association for Hand Surgery
Melissa Dang, Cat Shore-Lorenti, Lachlan B McMillan, Jakub Mesinovic, Alan Hayes, Peter R Ebeling, David Scott
Low vitamin D status commonly accompanies obesity, and both vitamin D deficiency and obesity have been associated with falls and fracture risk in older adults. We aimed to determine the associations of serum 25-hydroxyvitamin D (25(OH)D) concentrations with physical performance and bone health in community-dwelling, overweight and obese older men and women. Serum 25(OH)D concentrations were measured in 84 participants with body mass index ≥25 kg/m² (mean ± SD age 62.4 ± 7.9 years; 55% women). Physical function was determined by short physical performance battery, hand grip and quadriceps strength, and stair climb power tests...
February 12, 2019: International Journal of Environmental Research and Public Health
Yasuki Hori, Kazuki Hayashi, Itaru Naitoh, Hiroyuki Kato, Tatsuma Nomura, Katsuyuki Miyabe, Michihiro Yoshida, Naruomi Jinno, Makoto Natsume, Akihisa Kato, Go Asano, Shuji Takiguchi, Kiyokazu Nakajima
BACKGROUND AND AIMS: Migration of duodenal covered self-expandable metallic stents (C-SEMS) is the main cause of stent dysfunction in patients with malignant gastric outlet obstruction. However, the ideal method to prevent migration has not been clarified. We aimed to evaluate the feasibility and safety of duodenal C-SEMS fixation in this experimental study. METHODS: We used the over-the-scope clip (OTSC), suture, and clip methods to fix duodenal C-SEMS and evaluated the gripping force of each device and invasion depth based on pathological findings...
February 13, 2019: Surgical Endoscopy
Matthew J Clarkson, Paul N Bennett, Steve F Fraser, Stuart Anthony Warmington
BACKGROUND: Patients with end stage kidney disease on dialysis have increased mortality and reduced physical activity contributing to impaired physical function. While exercise programmes have demonstrated a positive effect on physiological outcomes such as cardiovascular function and strength, there is a reduced focus on physical function. The aim of this review was to determine whether exercise programmes improve objective measures of physical function indicative of activities of daily living for end stage kidney disease patients on dialysis...
February 13, 2019: American Journal of Physiology. Renal Physiology
Michelle E Baker, Kristen N DeCesare, Abby Johnson, Kathleen S Kress, Cynthia L Inman, Edward P Weiss
OBJECTIVE: Healthful dietary patterns have constituents that are known to improve exercise performance, such as antioxidants, nitrates, and alkalizing effects. However, ergogenic effects of such diets have not been evaluated. We hypothesized that a short-term Mediterranean diet results in better exercise performance, as compared to a typical Western diet. METHODS: Eleven recreationally active women (n = 7) and men (n = 4) (body mass index, 24.6 ± 3...
February 13, 2019: Journal of the American College of Nutrition
Hualiang Lin, Yanfei Guo, Zengliang Ruan, Paul Kowal, Qian Di, Yang Zheng, Jianpeng Xiao, Emiel O Hoogendijk, Elsa Dent, Michael G Vaughn, Steven W Howard, Zheng Cao, Wenjun Ma, Zhengmin Min Qian, Fan Wu
Background: Air pollution has been associated with various health outcomes. Its effect on hand-grip strength, a measurement of the construct of muscle strength and health status, remains largely unknown. Methods: We used the survey data from 31,209 adults ≥ 50 years of age within Wave 1 of the Study on Global AGEing and Adult Health in six low- and middle-income countries. The outdoor concentration of fine particulate matter pollution (PM2.5) was estimated using satellite data...
February 7, 2019: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Carlos A Celis-Morales, Jason M R Gill, Stuart R Gray
No abstract text is available yet for this article.
February 11, 2019: American Journal of Epidemiology
Tammy Y N Tong, Kathryn E Bradbury, Timothy J Key
No abstract text is available yet for this article.
February 12, 2019: American Journal of Epidemiology
Daniel Yilma, Alemseged Abdissa, Pernille Kæstel, Markos Tesfaye, Mette F Olsen, Tsinuel Girma, Christian Ritz, Henrik Friis, Åse B Andersen, Ole Kirk
BACKGROUND: Glomerular filtration rate estimating equations using serum creatinine are not validated in most African settings. We compared serum creatinine and estimated glomerular filtration rate (eGFR) in HIV positive and negative adults and assessed the performance of eGFR equations ((Cockcroft and Gault (CG), Modification of Diet in Renal Disease (MDRD), and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)) compared to 24-hour creatinine clearance in HIV positive adults...
2019: PloS One
Lena Hübner, Solveig Vieluf, Ben Godde, Claudia Voelcker-Rehage
It remains controversial whether aging influences motor learning, and whether physiological factors such as local strength or fitness are associated with fine motor performance and learning in older adults (OA). OA (n = 51) and young adults (YA; n = 31) performed a short-term motor learning session using a precision grip force modulation (FM) task. Rate of improvement of OA compared to YA was steeper with respect to performance variability and temporal precision. Both age groups showed positive transfer during an unpracticed variant of the FM task...
February 12, 2019: Journal of Aging and Physical Activity
Ines Doko, Žarko Bajić, Amir Dubravić, Merita Qorolli, Simeon Grazio
To examine the effect of endurance on the relationship between grip force and measures of functional capacity and disease activity, we performed a cross-sectional study at the University Department of Rheumatology, Physical medicine and Rehabilitation from January 2017 to August 2018. Functional capacity of the hand was measured by ABILHAND-RA questionnaire and disease activity was assessed by the Disease Activity Score (DAS-28-CRP). All participants underwent dynamometric measurements of maximal grip force and hand grip endurance during repeated gripping...
February 12, 2019: Rheumatology International
Hua-Zhu Wang, Jian-Yong Zhao, Zhi-Sheng Zhang
OBJECTIVE: To evaluate the efficacy of a novel dynamic distraction external fixator for proximal interphalangeal joint (PIPJ) fracture-dislocation. METHODS: From March 2005 to March 2014, 20 patients with PIPJ fracture-dislocation were treated with our technique. Function scores according to the Michigan Hand Outcome Questionnaire (MHQ) score, union time, grip strength, and range of motion (ROM) were recorded before and after treatment. RESULTS: All patients completed a mean follow-up of 22 months (range, 12-60 months)...
February 12, 2019: Journal of International Medical Research
Ali Al-Zuhairy, Søren H Sindrup, Henning Andersen, Johannes Jakobsen
OBJECTIVE: To evaluate the long-term outcome in Danish patients treated for multifocal motor neuropathy (MMN). METHODS: A population-based, cross-sectional study of patients referred to the Danish hospital system between 1985 and 2006. RESULTS: Thirty-four MMN patients were identified, three had died of unrelated diseases, 10 were excluded, one did not reply to study request and 20 were included. The median disease duration was 24 years (IQR: 18...
February 12, 2019: Journal of the Peripheral Nervous System: JPNS
D Stynen, N W H Jansen, J J M Slangen, A de Grip, I J Kant
PURPOSE: This study examines the relationship between need for recovery (NFR) and labour force exit (LFE) among older workers. Different types of LFE (early retirement, work disability and unemployment) are considered, and the role of potential confounding and modifying factors, including the availability of early LFE schemes, is examined. Also, associations between NFR and the intention and ability to prolong one's working life, which are known determinants of LFE, are assessed. METHODS: A subsample of older workers from the Maastricht Cohort Study was examined (n = 2312)...
February 11, 2019: International Archives of Occupational and Environmental Health
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