Chorong Han, Ji Ye Lim, Nobuya Koike, Sun Young Kim, Kaori Ono, Celia K Tran, Elizaveta Mangutov, Eunju Kim, Yanping Zhang, Lingyong Li, Amynah A Pradhan, Kazuhiro Yagita, Zheng Chen, Seung-Hee Yoo, Mark J Burish
OBJECTIVE: To characterize the circadian features of the trigeminal ganglion in a mouse model of headache. BACKGROUND: Several headache disorders, such as migraine and cluster headache, are known to exhibit distinct circadian rhythms of attacks. The circadian basis for these rhythmic pain responses, however, remains poorly understood. METHODS: We examined trigeminal ganglion ex vivo and single-cell cultures from Per2::LucSV reporter mice and performed immunohistochemistry...
January 30, 2024: Headache