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Trabeculectomy outcome

Herbert Reitsamer, Chelvin Sng, Vanessa Vera, Markus Lenzhofer, Keith Barton, Ingeborg Stalmans
PURPOSE: To evaluate the effectiveness of an ab interno subconjunctival gelatin implant as primary surgical intervention in reducing intraocular pressure (IOP) and IOP-lowering medication count in medically uncontrolled moderate primary open-angle glaucoma (POAG). METHODS: In this prospective, non-randomized, open-label, multicenter, 2-year study, eyes with medicated baseline IOP 18-33 mmHg on 1-4 topical medications were implanted with (phaco + implant) or without (implant alone) phacoemulsification...
February 13, 2019: Graefe's Archive for Clinical and Experimental Ophthalmology
Kazuhiko Umazume, Jun Suzuki, Yoshihiko Usui, Katsuhiko Maruyama, Yoshihiro Wakabayashi, Hiroshi Goto
Purpose: Bleb-related endophthalmitis (BRE) after glaucoma surgery is an infection caused by bacteria in the avascular bleb gaining access into the eye. We report the clinical features and outcome of 10 consecutive eyes with severe BRE treated at our hospital. Methods: Ten patients (10 eyes) with stage IIIb BRE after trabeculectomy diagnosed and treated at the Department of Ophthalmology, Tokyo Medical University, between April 2013 and May 2015, were studied. Patient background, type of glaucoma, interval from the first trabeculectomy, pretreatment bleb findings, causative microorganisms, surgical methods, status of posterior vitreous detachment (PVD), and postoperative visual acuity were examined...
2019: Journal of Ophthalmology
Soeren Waibel, Eberhard Spoerl, Olga Furashova, Lutz E Pillunat, Karin R Pillunat
PURPOSE: To study the longitudinal correlation between the clinical morphological appearance of filtering blebs with anterior segment optical coherence tomography (AS-OCT) in the early postoperative period. METHODS: Thirty eyes of 30 glaucoma patients scheduled for first-time trabeculectomy with mitomycin C 0.02% were consecutively enrolled. The filtering blebs were evaluated clinically according to a grading system and with AS-OCT at day 1 and weeks 1, 2, 3, 4 and 12 following surgery...
February 1, 2019: Journal of Glaucoma
Chengguo Zuo, Shufen Lin, Keling Wu, Ruowen Gong, Yafen Liu, Mingkai Lin, Jian Ge
PURPOSE: To investigate the predictors of long-term intraocular pressure (IOP) in chronic primary angle-closure glaucoma (CPACG) treated with primary trabeculectomy. METHODS: This study systematically reviewed cases of CPACG treated with primary trabeculectomy. The scleral flaps in all cases were sutured with two stitches in situ and two releasable sutures to ensure watertight under normal IOP conditions during surgery. Mitomycin C was used in all eyes. All patients were followed for 2 years...
January 24, 2019: International Ophthalmology
Arvind K Morya, Sahil Bhandari, Anushree Naidu
Purpose: Terminal chop, a new technique of nuclear segmentation, has been recently described in literature. The technique is considered to be a safe and effective option. Methods: We did a retrospective study to evaluate the outcome of terminal chop. Patients operated for terminal chop (phacoemulsification with or without trabeculectomy) from October 2016 to July 2018 were included in the study. Results: In all, 933 patients were included in the study...
February 2019: Indian Journal of Ophthalmology
Jin A Choi, Lina D Song, Seulggie Choi, Sang Min Park, Jin Woo Kwon, Donghyun Jee
OBJECTIVES: Open-angle glaucoma (OAG) imposes high disease burden in South Korea. Although various effective interventions are available to manage the progression of OAG, there is limited data on the cost-effectiveness of these treatment strategies in South Korea. METHODS: Using a Markov cohort model, we evaluated the cost-effectiveness of 3 major treatment strategies (medication, laser trabeculoplasty, and trabeculectomy) for South Korean patients with OAG. We projected a 25-year time horizon to study a hypothetical cohort of 10,000 patients of age 40 with mild OAG...
January 2019: Medicine (Baltimore)
Gonzalo Ordenes-Cavieres, Eduardo Pimentel, Jimena Schmidt
INTRODUCTION: Aqueous shunt has emerged as an alternative technique to trabeculectomy, which is considered the standard treatment for glaucoma surgery. Currently, it is mainly indicated after failure of trabeculectomy or in some types of glaucoma with high risk of failure. However, there is still controversy regarding its effectiveness compared to trabeculectomy. METHODS: We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others...
December 19, 2018: Medwave
Sharmila Rajendrababu, Sujani Shroff, Sangeeta Vivek Patil, Mohammed Sithiq Uduman, Ashok Vardhan, S R Krishnadas
Purpose: To evaluate the surgical outcomes of repeat trabeculectomy augmented with risk factor adjusted mitomycin C (MMC) exposure in eyes with previous failed trabeculectomy. Methods: Case records of 38 eyes of 37 patients with previous failed filter who underwent repeat trabeculectomy with MMC were reviewed retrospectively. Main outcome measures were best-corrected visual acuity (BCVA), intraocular pressure (IOP) reduction, requirement of anti-glaucoma medications, postoperative complications, and surgical success (defined as IOP of ≤21 mmHg and >5 mmHg along with 20% reduction from preoperative IOP with or without adjuvant medications) at 1-year postoperatively...
January 2019: Indian Journal of Ophthalmology
Anthony J King, Anupa Shah, Eleni Nikita, Kuang Hu, Caroline A Mulvaney, Richard Stead, Augusto Azuara-Blanco
BACKGROUND: Glaucoma is a leading cause of irreversible blindness. Subconjunctival draining minimally-invasive glaucoma devices such as the Xen gelatin implant and InnFocus stent have been introduced as a treatment to prevent glaucoma progressing.These implants provide a channel to allow aqueous humour from the anterior chamber of the eye to drain into the subconjunctival space on the surface of the eye thus reducing intraocular pressure (IOP) and mimicking the mechanism of the most commonly undertaken glaucoma surgery, trabeculectomy...
December 16, 2018: Cochrane Database of Systematic Reviews
Masoumeh Abbasi, Mehdi Naderi
No abstract text is available yet for this article.
December 10, 2018: Journal of Glaucoma
Jessica L M Ting, Christopher J Rudnisky, Karim F Damji
OBJECTIVE: To compare the efficacy and safety of ab interno trabeculectomy with the Trabectome combined with cataract surgery (phaco-AIT) versus Trabeculectomy with mitomycin C combined with cataract surgery (phaco-Trab) in open-angle glaucoma. METHODS: A prospective randomized controlled trial with a single surgeon and surgical center was undertaken. Patients were recruited from July 2009 to October 2014. Primary outcomes were mean intraocular pressure (IOP) at 6 months and surgical complications...
December 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Ivano Riva, Paolo Brusini, Francesco Oddone, Manuele Michelessi, Robert N Weinreb, Luciano Quaranta
Canaloplasty is a relatively new non-penetrating surgery for the reduction of intraocular pressure in patients affected by glaucoma. The technique uses a microcatheter to perform a 360 º cannulation of Schlemm's canal and leaves in place a tension suture providing an inward distension. It aims to restore the physiological outflow pathways of the aqueous humour and is independent of external wound healing. Several studies have shown that canaloplasty is effective in reducing intraocular pressure and has a low rate of complications, especially compared with trabeculectomy, the gold standard for glaucoma surgery...
November 28, 2018: Advances in Therapy
Rashmi G Mathew, Sahar Parvizi, Ian E Murdoch
AIMS: To compare success proportions at 5 years in three surgical groups: group 1, trabeculectomy alone; group 2, trabeculectomy followed by cataract surgery within 2 years; and group 3, trabeculectomy performed on a pseudophakic eye. METHODS: A retrospective cohort study. 194 eyes of 194 patients were identified with at least 5 years' follow-up post trabeculectomy (N=85, 60 and 49 in groups 1, 2 and 3, respectively). MAIN OUTCOME MEASURES: 1...
November 24, 2018: British Journal of Ophthalmology
Sirisha Senthil, Pasyanthi Balijepalli, Chandrasekhar Garudadri, Subhadra Jalali
PURPOSE: The purpose of this study was to report presentation and outcomes of coexisting congenital glaucoma with retinopathy of prematurity (ROP) in "Indian Twin cities ROP study (ITCROPS)." METHODS: Children with ROP and congenital glaucoma were identified from ITCROPS (prospective digital database) between 1997 and 2016. The presentation, interventions, and outcomes for glaucoma and ROP were evaluated. RESULTS: Out of 15,000 premature-infants database, 3000 children had ROP, of these 87 eyes of 64 premature children had glaucoma...
January 2019: Journal of Glaucoma
Hamed Esfandiari, Nils A Loewen, Kiana Hassanpour, Ali Fatourechi, Shahin Yazdani, Chao Wang, Mehdi Yaseri, Mohammad Pakravan
Background: The aim of this study was to compare the safety and efficacy of primary trabeculectomy with mitomycin C and Ahmed glaucoma valve (AGV) implantation in patients with Fuchs heterochromic iridocyclitis (FHIC)-related glaucoma, a rare complication of an uncommon form of uveitis. Method s : In this retrospective comparative case series, 26 FHIC-associated glaucoma patients received trabeculectomy (n=12) or an AGV (n=14). Primary outcome measures were surgical success, defined as intraocular pressure (IOP) ≤21 mmHg, decreasing ≥20% from baseline, and no secondary glaucoma surgery...
2018: F1000Research
Shogo Arimura, Seiji Miyake, Kentaro Iwasaki, Makoto Gozawa, Takehiro Matsumura, Yoshihiro Takamura, Masaru Inatani
We compared complications between Ex-PRESS implantation and trabeculectomy for 2 years after surgery. Sixty-four open-angle glaucoma eyes were randomly assigned to treatment with trabeculectomy (n = 32) or Ex-PRESS implantation (n = 32). The primary outcomes were postoperative complications, including reduction of the endothelial cell density (ECD) of the cornea, cataract progression and the frequency of other late postoperative complications. The Ex-PRESS group had significantly greater reduction of postoperative corneal ECD than the trabeculectomy group did at 2 years after surgery (P = 0...
November 1, 2018: Scientific Reports
Sudarshan Khokhar, Dev Yadav, Shikha Gupta, Ramanjit Sihota, Abadh Kishore Chaurasia, Amisha Gupta, Viney Gupta
AIM: To evaluate refractive outcomes of cataract surgery with intraocular lens (IOL) implantation in operated eyes of primary congenital glaucoma (PCG). DESIGN: A retrospective case-control study. METHODS: Patients of PCG who developed cataract following trabeculectomy with trabeculotomy were recruited. Preoperative biometry was recorded and refractive outcomes of the patients in terms of spherical equivalent (SE) and prediction error were noted at 3 and at 12 months following surgery...
October 31, 2018: Eye
Jacquelyn Daubert, Terrence P O'Brien, Eldad Adler, Oriel Spierer
BACKGROUND: A major obstacle that academic institutions face is the steep learning curve for cornea fellows initially learning to perform Descemet Stripping Endothelial Keratoplasty (DSEK). The purpose of this study is to evaluate the outcomes of complex DSEK performed by cornea fellow supervised by an attending surgeon at an academic institution. METHODS: Patients who underwent a complex DSEK procedure performed by a cornea fellow during the years 2009-2013 were included...
October 30, 2018: BMC Ophthalmology
Vivek Pravin Dave, Joveeta Joseph, Avinash Pathengay, Rajeev R Pappuru, Taraprasad Das
PURPOSE: To describe the clinical presentation and management of Curvularia endophthalmitis and compare with previous published literature. METHODS: Retrospective interventional comparative case series and literature review. Eight cases with culture-proven Curvularia endophthalmitis from January 2000 to March 2018 underwent vitrectomy/vitreous biopsy, intravitreal antibiotic with or without additional procedures as appropriate. The undiluted vitreous biopsy was subjected to microbiologic evaluation...
October 23, 2018: Retina
Lina Krėpštė, Reda Žemaitienė, Arūnas Miliauskas
Background and objectives: Despite established common risk factors, malignant glaucoma (MG) remains a rare condition with challenging management. We aimed to analyze differences in risk factors for MG after different surgeries and outcomes after pars plana vitrectomy (PPV). Materials and Methods: This retrospective study included cases of MG treated with PPV between January 2005 and December 2015 in the Department of Ophthalmology, Lithuanian University of Health Sciences, Kaunas, Lithuania. Results: A total of 39 cases were analyzed: 23 (59%) after cataract surgery, 13 (33...
September 5, 2018: Medicina
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