Monika Sadlonova, Laura Duque, Diana Smith, Elizabeth N Madva, Hermioni L Amonoo, Jonathan Vogelsang, Sophie C Staton, Christine A F von Arnim, Jeff C Huffman, Christopher M Celano
OBJECTIVE: We conducted an updated, comprehensive, and contemporary systematic review to examine the efficacy of existing pharmacologic agents employed for management of delirium symptoms among hospitalized adults. METHODS: Searches of PubMed, Scopus, Embase, and Cochrane Library databases from inception to May 2021 were performed to identify studies investigating efficacy of pharmacologic agents for management of delirium. RESULTS: Of 11,424 articles obtained from searches, a total of 33 articles (N = 3030 participants) of randomized or non-randomized trials, in which pharmacologic treatment was compared to active comparator, placebo, or no treatment, met all criteria and were included in this review...
2022: General Hospital Psychiatry