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https://read.qxmd.com/read/30868258/adherence-to-diabetes-care-process-indicators-in-migrants-as-compared-to-non-migrants-with-diabetes-a-retrospective-cohort-study
#1
Giuseppe Seghieri, Chiara Seghieri, Laura Policardo, Elisa Gualdani, Paolo Francesconi, Fabio Voller
OBJECTIVES: Prevalence rate of diabetes is high among migrants. Whether migrants are correctly addressed to a standard quality of care for diabetes and are properly followed up are the questions addressed by this retrospective cohort study. METHODS: Compliance to one or repeated Guideline Composite Indicator (GCI), a standard process indicator of care quality, was tested in migrants compared to non-migrant Italian residents with diabetes, living in Tuscany Region, Italy, in years 2011-2015...
March 13, 2019: International Journal of Public Health
https://read.qxmd.com/read/30854895/prevalence-of-diabetes-and-diabetic-macular-edema-in-patients-undergoing-senile-cataract-surgery-in-italy-the-diabetes-and-cataract-study
#2
Giacomo Panozzo, Giovanni Staurenghi, Giulia Dalla Mura, Diana Giannarelli, Giovanni Alessio, Salvatore Alongi, Romolo Appolloni, Antonio Baldascino, Francesco Boscia, Aldo Caporossi, Matteo Cereda, Erminia D'Ugo, Matteo Fallico, Teresio Avitabile, Alessandro Galan, Carlo La Spina, Giuseppe Lo Giudice, Leonardo Mastropasqua, Carmela Palmisano, Claudio Panico, Maria Cristina Parravano, Rachele Penna, Pierangelo Pintore, Agostino Vaiano, Michele Reibaldi, Stanislao Rizzo, Tommaso Rossi, Monica Varano, Gianni Virgili
BACKGROUND: The purpose of this study is to determine the prevalence of diabetes and diabetic macular edema in patients undergoing senile cataract surgery in Italy. METHODS: It is a prospective, multicenter, cross-sectional study. Thirteen ophthalmic units equally distributed across the Italian territory have been involved in the study. For a period of 3 months, all subjects undergoing phacoemulsification received an Optical Coherence Tompgraphy (OCT) scan and were screened for the anamnestic presence of diabetes...
March 11, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30815830/eadsg-guidelines-insulin-storage-and-optimisation-of-injection-technique-in-diabetes-management
#3
REVIEW
Silver Bahendeka, Ramaiya Kaushik, Andrew Babu Swai, Fredrick Otieno, Sarita Bajaj, Sanjay Kalra, Charlotte M Bavuma, Claudine Karigire
To date, insulin therapy remains the cornerstone of diabetes management; but the art of injecting insulin is still poorly understood in many health facilities. To address this gap, the Forum for Injection Technique and Therapy Expert Recommendations (FITTER) published recommendations on injection technique after a workshop held in Rome, Italy in 2015. These recommendations are generally applicable to the majority of patients on insulin therapy, athough they do not explore alternative details that may be suitable for low- and middle-income countries...
February 27, 2019: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://read.qxmd.com/read/30804842/assessment-of-psychological-dimensions-in-telemedicine-care-for-gestational-diabetes-mellitus-a-systematic-review-of-qualitative-and-quantitative-studies
#4
Stefania Fantinelli, Daniela Marchetti, Maria Cristina Verrocchio, Marica Franzago, Mario Fulcheri, Ester Vitacolonna
Background and Objective: Gestational Diabetes Mellitus (GDM) is a complex and wide spread problem and is considered one of the most frequent chronic metabolic conditions during pregnancy. According to a recent consensus conference held in Italy, new technologies can play a role in the so-called process of fertilization of the individual's ecosystem engagement, representing support for systemic collaboration among the main actors. The current systematic review aimed at providing an update of the literature about telemedicine for GDM, considering the role of psychological dimensions such as empowerment/self-efficacy, engagement and satisfaction...
2019: Frontiers in Psychology
https://read.qxmd.com/read/30793466/effects-of-valsartan-benazepril-and-their-combination-in-overt-nephropathy-of-type-2-diabetes-a-prospective-randomized-controlled-trial
#5
Piero Ruggenenti, Matias Trillini, Drazenka P Barlovic, Monica Cortinovis, Antonio Pisani, Aneliya Parvanova, Ilian P Iliev, Barbara Ruggiero, Stefano Rota, Maria C Aparicio, Annalisa Perna, Francesco Peraro, Olimpia Diadei, Flavio Gaspari, Fabiola Carrara, Nadia Stucchi, Davide Martinetti, Andrej Janez, Nadan Gregoric, Eleonora Riccio, Antonio C Bossi, Roberto Trevisan, Paolo Manunta, Giovanni Battaglia, Salvatore David, Filippo Aucella, Antonio Belviso, Andrea Satta, Giuseppe Remuzzi
AIMS: To evaluate whether angiotensin-converting enzyme (ACE) inhibitor and angiotensin II receptor blocker (ARB) combination therapy is more nephroprotective than ACE inhibitor or ARB monotherapy in people with type 2 diabetes and overt nephropathy. MATERIALS AND METHODS: In this prospective, randomized, open, blind-endpoint phase III trial sponsored by the Italian Drug Agency, 103 consenting patients with type 2 diabetes, aged >40 years, with serum creatinine levels 159 to 309 μmol/L, spot morning urinary albumin-creatinine ratio > 1000 mg/g (or > 500 mg/g in those on ACE inhibitor or ARB therapy at inclusion) were stratified by centre and randomized to 4...
February 22, 2019: Diabetes, Obesity & Metabolism
https://read.qxmd.com/read/30785928/high-quality-process-of-care-increases-one-year-survival-after-acute-myocardial-infarction-ami-a-cohort-study-in-italy
#6
Martina Ventura, Valeria Belleudi, Paolo Sciattella, Riccardo Di Domenicantonio, Mirko Di Martino, Nera Agabiti, Marina Davoli, Danilo Fusco
BACKGROUND: The relationship between guideline adherence and outcomes in patients with acute myocardial infarction (AMI) has been widely investigated considering the emergency, acute, post-acute phases separately, but the effectiveness of the whole care process is not known. AIM: The study aim was to evaluate the effect of the multicomponent continuum of care on 1-year survival after AMI. METHODS: We conducted a cohort study selecting all incident cases of AMI from health information systems during 2011-2014 in the Lazio region...
2019: PloS One
https://read.qxmd.com/read/30759309/osteocalcin-bone-gla-protein-levels-vascular-calcifications-vertebral-fractures-and-mortality-in-hemodialysis-patients-with-diabetes-mellitus
#7
Maria Fusaro, Maurizio Gallieni, Andrea Aghi, Maria Antonietta Rizzo, Giorgio Iervasi, Thomas L Nickolas, Fabrizio Fabris, Maria Cristina Mereu, Sandro Giannini, Stefania Sella, Andrea Giusti, Annalisa Pitino, Graziella D'Arrigo, Maurizio Rossini, Davide Gatti, Maura Ravera, Luca Di Lullo, Antonio Bellasi, Giuliano Brunori, Antonio Piccoli, Giovanni Tripepi, Mario Plebani
BACKGROUND AND AIMS: Diabetes mellitus is recognized as one of the major causes of end stage kidney disease. Bone Gla protein (BGP) is a vitamin K-dependent protein involved in bone mineralization and vascular calcifications (VC). Our goal was to characterize BGP and undercarboxylated BGP (ucBGP) in DM patients on HD, compared to HD patients without DM, and their association with vascular and bone disease. METHODS: 387 HD patients from 18 dialysis centers in Italy...
February 13, 2019: Journal of Nephrology
https://read.qxmd.com/read/30725263/gender-difference-in-the-risk-for-cardiovascular-events-or-mortality-of-patients-with-diabetic-foot-syndrome
#8
Giuseppe Seghieri, Laura Policardo, Elisa Gualdani, Roberto Anichini, Paolo Francesconi
AIMS: Diabetic foot syndrome (DFS) increases the risk for atherosclerotic cardiovascular disease (ASCVD), chronic kidney disease (CKD), or mortality. The present study aims at ascertaining whether such DFS-related excess risk differs between genders, retrospectively investigating a population with diabetes from Tuscany, Italy, followed-up for 6 years (2011-2016). METHODS: People with diabetes living in Tuscany on January 1st 2011 identified by administrative databases, were divided by baseline history of prior DFS hospitalizations, stratified by presence/absence of peripheral vascular disease and evaluating, by Cox regression analysis, whether adjusted DFS-related excess risk of incident ASCVD, CKD or mortality differed between genders...
February 5, 2019: Acta Diabetologica
https://read.qxmd.com/read/30697572/burden-and-characteristics-of-the-comorbidity-tuberculosis-diabetes-in-europe-tbnet-prevalence-survey-and-case-control-study
#9
Monica Sane Schepisi, Assunta Navarra, M Nieves Altet Gomez, Andrii Dudnyk, Anne Margarita Dyrhol-Riise, Jaime Esteban, Pier Francesco Giorgetti, Gina Gualano, Lorenzo Guglielmetti, Jan Heyckendorf, Anna Kaluzhenina, Berit Lange, Christoph Lange, Katerina Manika, Jalal Miah, Zorica Nanovic, Emanuele Pontali, Monica Rios Prego, Ivan Solovic, Simon Tiberi, Fabrizio Palmieri, Enrico Girardi
Background: The growing burden of diabetes mellitus (DM) is posing a threat to global tuberculosis (TB) control. DM triples the risk of developing TB, modifies the presenting features of pulmonary TB, and worsens TB treatment outcomes. We aimed to analyze the prevalence of DM among TB patients and to describe the characteristics and clinical presentation of TB-DM patients in Europe. Methods: We performed a cross-sectional survey on the prevalence of DM among consecutively diagnosed adult TB patients in 11 European TB referral centers located in France, Germany, Greece, Italy, Russia, Slovakia, Spain, and the United Kingdom over the period 2007-2015...
January 2019: Open Forum Infectious Diseases
https://read.qxmd.com/read/30659908/associations-between-cervical-breast-and-colorectal-cancer-screening-uptake-chronic-diseases-and-health-related-behaviours-data-from-the-italian-passi-nationwide-surveillance
#10
Francesco Venturelli, Letizia Sampaolo, Giuliano Carrozzi, Marco Zappa, Paolo Giorgi Rossi
Screening programmes have been proposed as a privileged setting for health promotion interventions. We aim to assess the associations between behavioural risk factors, chronic conditions and diseases and cervical, breast and colorectal cancer screening uptake. Secondly, we aim to assess whether these associations are due to underlying differences in socioeconomic characteristics. In Italy, a random sample was interviewed by the PASSI surveillance (106,000 interviews) in 2014-2016. Screening uptake adjusted for age and gender alone and for age, gender and socioeconomic characteristics (educational attainment and self-reported economic difficulties) were estimated using multivariate Poisson regression models...
January 16, 2019: Preventive Medicine
https://read.qxmd.com/read/30637678/the-role-of-maternal-citizenship-on-pediatric-avoidable-hospitalization-a-birth-cohort-study-in-north-east-italy
#11
REVIEW
Andrea Bardin, Teresa Dalla Zuanna, Susanna Favarato, Lorenzo Simonato, Loris Zanier, Rosanna Irene Comoretto, Cristina Canova
OBJECTIVE: Avoidable hospitalization (AH) has been widely studied as a possible measure of primary health care performance. Since studies evaluating AH in migrant children, particularly in Europe, are lacking, the aim of this study was to investigate the role of maternal citizenship on the risk of AH in children. METHODS: The cohort study included all live newborns recorded in the Medical Birth Register (MBR) of Friuli-Venezia Giulia Region (Italy) in the years 1989-2012, followed from 30 d after their birth up to the 14th year of life...
January 12, 2019: Indian Journal of Pediatrics
https://read.qxmd.com/read/30613002/factors-associated-with-increased-risk-of-de-novo-or-recurrent-hepatocellular-carcinoma-in-patients-with-cirrhosis-treated-with-direct-acting-antivirals-for-hcv-infection
#12
Elisabetta Degasperi, Roberta D'Ambrosio, Massimo Iavarone, Angelo Sangiovanni, Alessio Aghemo, Roberta Soffredini, Marta Borghi, Giovanna Lunghi, Massimo Colombo, Pietro Lampertico
BACKGROUND & AIMS: Patients with cirrhosis and hepatitis C virus (HCV) infection treated with direct-acting antivirals (DAAs) are still at risk for developing hepatocellular carcinoma (HCC). We aimed to identify features of de novo or recurrent HCCs in these patients, and factors associated with HCC development, in a large cohort of patients with cirrhosis who received treatment with DAAs. METHODS: In a retrospective study, we collected data from 565 patients with cirrhosis (median age, 64 years; range, 28-87 years; 60% male, 49% infected with HCV genotype 1; median liver stiffness measurement [LSM], 19...
October 26, 2018: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/30603867/ten-years-of-experience-with-dpp-4-inhibitors-for-the-treatment-of-type-2-diabetes-mellitus
#13
REVIEW
Giorgio Sesti, Angelo Avogaro, Sara Belcastro, Benedetta Maria Bonora, Marina Croci, Giuseppe Daniele, Marco Dauriz, Francesco Dotta, Caterina Formichi, Simona Frontoni, Cecilia Invitti, Emanuela Orsi, Fabiana Picconi, Veronica Resi, Enzo Bonora, Francesco Purrello
Achieving and maintaining recommended glycemic targets without causing adverse e ffects, including hypoglycemia, is challenging, especially in older patients with type 2 diabetes mellitus (T2DM). The introduction of dipeptidyl peptidase-4 (DPP-4) inhibitors, more than 10 years ago, has provided an alternative to conventional medications for the intensification of glucose-lowering treatment after failure of metformin monotherapy, and therefore, marked an important advance in the management of T2DM. By prolonging the activity of incretin hormones, DPP-4 inhibitors induce insulin release and decrease glucagon secretion in a glucose-dependent manner...
January 2, 2019: Acta Diabetologica
https://read.qxmd.com/read/30603641/red-blood-cell-distribution-width-rdw-is-an-independent-predictor-of-post-implantation-syndrome-in-patients-undergoing-endovascular-aortic-repair-for-abdominal-aortic-aneurysm
#14
Gian Franco Veraldi, Luca Mezzetto, Lorenzo Scorsone, Marco Macrì, Chiara Bovo, Fabio Simoncini, Paolo Criscenti, Giuseppe Lippi
Background: This observational, retrospective study aims establishing the role of red blood cell distribution width (RDW) for identifying abdominal aortic aneurism (AAA) patients at risk of developing post-implantation syndrome (PiS) after endovascular aneurysm repair (EVAR). Methods: The study population consisted of all patients undergoing EVAR for AAA at the University Hospital of Verona (Italy), between June 1, 2016 and May 31, 2018. Blood samples for measuring hemoglobin, mean corpuscular volume (MCV) and RDW were collected at hospital admission and the day after EVAR...
December 2018: Annals of Translational Medicine
https://read.qxmd.com/read/30591815/effects-of-different-anticoagulants-on-glycated-albumin-quantification
#15
Graziella Bonetti, Nicola Di Gaetano, Renata Paleari, Ferruccio Ceriotti
Introduction: In the last 20 years glycated albumin (GA) measurement has been demonstrated to be a reliable glycation marker and recently as the most innovative one in western countries. Glycated albumin has been already adopted by some Asian countries due to its usefulness in diabetes screening. The aim of the present study was to investigate for the first time the effects of different anticoagulants on GA assay. Materials and methods: From each of 60 patients a serum tube and K3 EDTA, Li-Heparin and NaF-EDTA containing tubes were collected...
February 15, 2019: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://read.qxmd.com/read/30589831/global-patterns-and-trends-in-pancreatic-cancer-incidence-age-period-and-birth-cohort-analysis
#16
Ganfeng Luo, Yanting Zhang, Pi Guo, Huanlin Ji, Yuejiao Xiao, Ke Li
OBJECTIVES: We aim to provide a global geographical picture of pancreatic cancer incidence and temporal trends from 1973 to 2015 for 41 countries. METHODS: Joinpoint regression and age-period-cohort model was used. RESULTS: In 2012, the highest age-adjusted rate was in Central and Eastern Europe for male and North America for female. Most regions showed sex disparities. During the recent 10 years, increasing trends were observed in North America, Western Europe, and Oceania...
December 21, 2018: Pancreas
https://read.qxmd.com/read/30577264/survival-after-lung-transplant-for-cystic-fibrosis-in-italy-a-single-center-experience-with-20-years-of-follow-up
#17
D Savi, M Mordenti, E Bonci, P Troiani, B Giordani, V D'Alù, S Bertasi, G Cimino, P Rossi, C Poggi, P Palange, S Quattrucci
OBJECTIVES: Lung transplantation is currently the only treatment for end-stage respiratory failure in patients with cystic fibrosis (CF). In this study we retrospectively analyzed our experience since the start of the transplantation program in 1996 with focus on survival analysis. METHODS: All patients with CF who underwent lung transplant at our center were included (1996-2016). Survival analysis after lung transplant was performed using the Kaplan-Meier estimate, comparing by sex and by 4 eras (1996-2000, 2001-2005, 2006-2010, and 2011-2016)...
December 2018: Transplantation Proceedings
https://read.qxmd.com/read/30556373/cardiovascular-risk-profiling-of-long-lived-people-shows-peculiar-associations-with-mortality-compared-with-younger-individuals
#18
Alberto Montesanto, Daniela Pellegrino, Silvana Geracitano, Daniele La Russa, Vincenzo Mari, Sabrina Garasto, Fabrizia Lattanzio, Andrea Corsonello, Giuseppe Passarino
AIM: Centenarians represent a biological model of successful aging because they escaped/postponed most invalidating age-related diseases, such as cardiovascular diseases. The aim of the present study was to clarify whether a favorable cardiovascular risk profile increases the survival chances in long-lived people. METHODS: A total of 355 community-dwelling nonagenarians and centenarians living in Southern Italy were recruited in the study. Patients were classified as at low and high cardiovascular risk on the basis of serum cholesterol, diabetes, hypertension and smoking status...
December 16, 2018: Geriatrics & Gerontology International
https://read.qxmd.com/read/30555339/a-cross-sectional-analysis-of-body-composition-among-healthy-elderly-from-the-european-nu-age-study-sex-and-country-specific-features
#19
Aurelia Santoro, Alberto Bazzocchi, Giulia Guidarelli, Rita Ostan, Enrico Giampieri, Daniele Mercatelli, Maria Scurti, Agnes Berendsen, Olga Surala, Amy Jennings, Nathalie Meunier, Elodie Caumon, Rachel Gillings, Fawzi Kadi, Frederic Capel, Kevin D Cashman, Barbara Pietruszka, Edith J M Feskens, Lisette C P G M De Groot, Giuseppe Battista, Stefano Salvioli, Claudio Franceschi
Body composition (BC) is an emerging important factor for the characterization of metabolic status. The assessment of BC has been studied in various populations and diseases such as obesity, diabetes, endocrine diseases as well as physiological and paraphysiological conditions such as growth and aging processes, and physical training. A gold standard technique for the assessment of human BC at molecular level is represented by dual-energy X-ray absorptiometry (DXA), which is able to precisely assess the body mass (and areal bone mineral density-aBMD) on a regional and whole-body basis...
2018: Frontiers in Physiology
https://read.qxmd.com/read/30554250/triple-therapy-at-discharge-from-internal-medicine-wards-in-heart-failure-patients-with-reduced-ejection-fraction-results-from-an-observational-study
#20
A Fortini, V Verdiani, G Panigada, C Angotti, L Masotti
BACKGROUND: Guidelines recommend triple therapy (TT) with ACE inhibitors or ARBs, beta-blockers and mineralcorticoid receptor antagonists in symptomatic heart failure patients with ejection fraction <35 % (HFrEF). Nevertheless, many patients remain untreated. This study was aimed to evaluate the use of TT in HFrEF patients discharged from internal medicine wards of Tuscany, Italy. METHODS AND RESULTS: We analyzed the database of a multicenter observational study which included 770 patients consecutively hospitalized for HF in 32out of 36 Internal Medicine Units of Tuscany, Italy...
November 2018: La Clinica Terapeutica
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