Zhiyong Shen, Dong Xue, Kun Wang, Facai Zhang, Jiaqi Shi, Benzhong Jia, Dan Yang, Qianjin Zhang, Shuai Zhang, Hongyu Jiang, Daiqin Luo, Xueying Li, Quliang Zhong, Junhao Zhang, Zheng Peng, Yu Han, Chongyang Sima, Xiaozhou He, Lin Hao
BACKGROUND: To observe and explore the effect of metformin on the migration and proliferation of bladder cancer T24 and 5637 cells in vitro. METHODS: Bladder cancer T24 and 5637 cell lines were cultured in vitro, and were divided into group A (blank control group) and group B (metformin group: 5, 10, 15, and 20 mmol/L); both groups were plated on 6-well plates at the same time. Culture in 24-well plates was used for wound healing assays and in 96-well plates for Transwell migration and invasion, and Cell Counting Kit-8 proliferation experiments...
May 24, 2022: BMC Urology