Matthew P Abdel, Harold I Salmons, Dirk R Larson, Matthew S Austin, C Lowry Barnes, Michael P Bolognesi, Craig J Della Valle, Douglas A Dennis, Kevin L Garvin, Jeffrey A Geller, Stephen J Incavo, Adolph V Lombardi, Christopher L Peters, Ran Schwarzkopf, Peter K Sculco, Bryan D Springer, Mark W Pagnano, Daniel J Berry
INTRODUCTION: Manipulation under anesthesia (MUA) occurs in 4% of patients after total knee arthroplasty (TKA). Anti-inflammatory medications may target arthrofibrosis pathogenesis, but the data are limited. This multicenter randomized clinical trial (RCT) investigated the effect of adjuvant anti-inflammatory medications with MUA and physical therapy (PT) on range of motion (ROM) and outcomes. METHODS: There were 124 patients (124 TKAs) who developed stiffness after primary TKA for osteoarthritis enrolled across 15 institutions...
February 26, 2024: Journal of Arthroplasty