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Vibeke Oestergaard Steenfeldt, Minna Therkildsen, Jette Lind
BACKGROUND: The balance between lessons prepared to challenge the talented students and students who find the courses difficult is a recurrent dilemma in the Danish nurse education. Challenging talented students while pitching the learning appropriately for less able students is a recurring dilemma in education. In Danish nursing courses, the gap between these two kinds of student becomes particularly obvious in fifth semester theoretical courses. METHOD: To provide knowledge of students' experiences of challenging courses a phenomenological approach was adopted...
February 6, 2019: Nurse Education Today
Junji Hou, Guoqun Zhao, Lei Zhang, Guilong Wang, Bo Li
The preparation of high-expansion open-cell foam for oil spill clean-ups is important, but still challenging with linear isotactic polypropylene (PP). Therefore, a cooling batch foaming method was designed to fabricate the high-expansion PP foams using supercritical CO2 as a blowing agent. To investigate the relation between the crystallization and foaming of PP, an in-situ visualization system was employed. It is found that the CO2 dissolved in polymer melt depresses the crystallization temperature and nucleation of PP...
February 7, 2019: Journal of Colloid and Interface Science
D Alloni, M Prata, B Smilgys
In this work we present a characterization of the radionuclidic impurities originated by proton irradiation of enriched water [18 O]H2 O in a medical cyclotron through Monte Carlo simulations and experimental measurements. A set of standard samples of enriched water loaded in the cyclotron target cell have been irradiated at 30 μA proton current for 1 h each and, after an appropriate cooling time, measured by HPGe gamma spectrometry. In this way it was possible to study the direct release of radionuclidic impurities from target components as well as the release as a function of target ageing...
January 31, 2019: Applied Radiation and Isotopes
M Pellegrini, M Bloemendal, N Hoekstra, G Spaak, A Andreu Gallego, J Rodriguez Comins, T Grotenhuis, S Picone, A J Murrell, H J Steeman
A transition to a low carbon energy system is needed to respond to global challenge of climate change mitigation. Aquifer Thermal Energy Storage (ATES) is a technology with worldwide potential to provide sustainable space heating and cooling by (seasonal) storage and recovery of heat in the subsurface. However, adoption of ATES varies strongly across Europe, because of both technical as well as organizational barriers, e.g. differences in climatic and subsurface conditions and legislation respectively. After identification of all these barriers in a Climate-KIC research project, six ATES pilot systems have been installed in five different EU-countries aiming to show how such barriers can be overcome...
January 15, 2019: Science of the Total Environment
Véronique Vermeersch, Olivier Huet
No abstract text is available yet for this article.
February 11, 2019: Anaesthesia, Critical Care & Pain Medicine
Laurent M A Favié, Floris Groenendaal, Marcel P H van den Broek, Carin M A Rademaker, Timo R de Haan, Henrica L M van Straaten, Peter H Dijk, Arno van Heijst, Jeroen Dudink, Koen P Dijkman, Monique Rijken, Inge A Zonnenberg, Filip Cools, Alexandra Zecic, Johanna H van der Lee, Debbie H G M Nuytemans, Frank van Bel, Toine C G Egberts, Alwin D R Huitema
OBJECTIVE: Morphine is a commonly used drug in encephalopathic neonates treated with therapeutic hypothermia after perinatal asphyxia. Pharmacokinetics and optimal dosing of morphine in this population are largely unknown. The objective of this study was to describe pharmacokinetics of morphine and its metabolites morphine-3-glucuronide and morphine-6-glucuronide in encephalopathic neonates treated with therapeutic hypothermia and to develop pharmacokinetics based dosing guidelines for this population...
2019: PloS One
Riccardo Scott, Anatol V Prudnikau, Artsiom Antanovich, Sotirios Christodoulou, Thomas Riedl, Guillaume H V Bertrand, Nina Owschimikow, Jörg K N Lindner, Zeger Hens, Iwan Moreels, Mikhail Artemyev, Ulrike Woggon, Alexander W Achtstein
In a comparative study we investigate the carrier-phonon coupling in CdSe based core-only and hetero 2D as well as 0D nanoparticles. We demonstrate that the coupling can be strongly tuned by the lateral size of nanoplatelets, while, due to the weak lateral confinement, the transition energies are only altered by tens of meV. Our analysis shows that an increase in the lateral platelet area results in a strong decrease in the phonon coupling to acoustic modes due to deformation potential interaction, yielding an exciton deformation potential of 3...
February 14, 2019: Nanoscale
D V Pominova, I D Romanishkin, P V Grachev, A V Borodkin, A S Vanetsev, E O Orlovskaya, Yu V Orlovskii, I Sildos, V B Loschenov, A V Ryabova
To improve methods of laser hyperthermia for the treatment of bulk malignant neoplasms, an urgent task is the development of techniques and devices that automatically control heating at a given tissue depth and ensure its uniformity. The article proposes the concept of a system for performing hyperthermia with real-time spectroscopic temperature control and surface cooling, which allows to record spectra of diffusely scattered radiation and fluorescent signal from various depths of biological tissues by the means of the variation of the angle and distance between the fiber source of laser radiation and the receiving fiber...
February 14, 2019: Lasers in Medical Science
Myung Sub Kim, Hyun Pyo Hong, Kyungmin Park, Kyung A Kang, Sung Ryol Lee
PURPOSE: To evaluate the efficacy of cisplatin-infused and normal saline-infused radiofrequency ablation (RFA) with internally cooled perfusion (ICP) electrode. MATERIALS AND METHODS: Using a 200 W generator, thirty ablation zones were created and divided into three groups of 10 each as follows: group A, RFA alone with 16 gauge monopolar internally cooled (IC) electrode; group B, cisplatin-infused RFA with 16 gauge ICP electrode; and group C, normal saline-infused RFA with 16 gauge ICP electrode...
February 13, 2019: Cardiovascular and Interventional Radiology
Linxiao Zhu, Anthony Fiorino, Dakotah Thompson, Rohith Mittapally, Edgar Meyhofer, Pramod Reddy
Photonic cooling of matter has enabled both access to unexplored states of matter, such as Bose-Einstein condensates, and novel approaches to solid-state refrigeration1-3 . Critical to these photonic cooling approaches is the use of low-entropy coherent radiation from lasers, which makes the cooling process thermodynamically feasible4-6 . Recent theoretical work7-9 has suggested that photonic solid-state cooling may be accomplished by tuning the chemical potential of photons without using coherent laser radiation, but such cooling has not been experimentally realized...
February 2019: Nature
Yannick De Wilde, Riad Haidar
No abstract text is available yet for this article.
February 2019: Nature
Črt Dragar, Tanja Potrč, Sebastjan Nemec, Robert Roškar, Stane Pajk, Petra Kocbek, Slavko Kralj
The development of various magnetically-responsive nanostructures is of great importance in biomedicine. The controlled assembly of many small superparamagnetic nanocrystals into large multi-core clusters is needed for effective magnetic drug delivery. Here, we present a novel one-pot method for the preparation of multi-core clusters for drug delivery (i.e., magnetic nanocarriers). The method is based on hot homogenization of a hydrophobic phase containing a nonpolar surfactant into an aqueous phase, using ultrasonication...
February 12, 2019: Materials
Feng-Yi Lin, Kuo-Tsang Huang, Tzu-Ping Lin, Ruey-Lung Hwang
As urbanization expands and diversifies, weather data produced by a single weather station in a suburb are no longer adequate to represent and reflect microclimatic changes of a city. This study selected 34 automatic weather stations in Tainan City, Taiwan, to conduct temperature and humidity measurements over a period of one year. Based on those observed weather data and urban environment parameters obtained from a geographic information system, as well as morphing approach, this study constructed a method of generating hourly local weather data for urban areas while accounting for urban heat island (UHI) effect in summer...
February 25, 2019: Science of the Total Environment
Benjamin Richard, Goetz M Richter, Marianna Cerasuolo, Ian Shield
Background and Aims: Bioenergy is central for the future energy mix to mitigate climate change impacts; however, its intricate link with the water cycle calls for an evaluation of the carbon-water nexus in biomass production. The great challenge is to optimize trade-offs between carbon harvest and water use by choosing cultivars that combine low water use with high productivity. Methods: Regional scenarios were simulated over a range of willow genotype × environment interactions for the major UK soil × climate variations with the process-based model LUCASS...
February 13, 2019: Annals of Botany
Tomomi Fujimoto, Bun Tsuji, Yosuke Sasaki, Kohei Dobashi, Yasuo Sengoku, Naoto Fujii, Takeshi Nishiyasu
Hypothermia can occur during aquatic exercise, despite production of significant amounts of heat by the active muscles. Because the characteristics of human thermoregulatory responses to cold during exercise have not been fully elucidated, we investigated the effect of low-intensity exercise on the shivering response to core cooling in cool water. Eight healthy young men (24±3 years) were cooled through cool water immersion while resting (rest trial) and during loadless pedaling on a water cycle ergometer (exercise trial)...
February 13, 2019: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Ranjeet Kaur, Kshitija Sinha, Rupam Kumar Bhunia
Wheat is an important cereal crop that fulfils the calorie demands of the global humanity. Rapidly expanding populations are exposed to a fast approaching acute shortage in the adequate supply of food and fibre from agricultural resources. One of the significant threats to food security lies in the constantly increasing global temperatures which inflict serious injuries to the plants in terms of various physiological, biochemical and molecular processes. Wheat being a cool season crop is majorly impacted by the heat stress which adversely affects crop productivity and yield...
February 13, 2019: Molecular Biology Reports
A P Gutierrez, L Ponti, P A Arias
Before its eradication from North America, the subtropical-tropical new world screwworm fly Cochliomyia hominivorax (Coquerel) invaded southwestern temperate areas of the U.S.A., where it caused myiasis in wildlife and livestock. Outbreaks of the fly occurred during years when adult migrants were carried northward on North American monsoon winds from the northern areas of Mexico and south Texas. We deconstruct, retrospectively, the biology and the effect of weather on the eradication of the fly in North America...
February 13, 2019: Medical and Veterinary Entomology
Xiaoming Ren, Chen Xue, Shu Wang, Wen-Long Liu
A direct bandgap 2D corrugated layer lead chloride hybrid, [(CH3)4N]4Pb3Cl10 (1), shows analogous topology to the {Mg3F104-}᪲ layer in Cs4Mg3F10, and two different (CH3)4N+ cations locate in the inorganic layer voids and between inter-layers, respectively. Two reversible structural phase transitions undergo in 1 at 225/210 K and 328/325 K upon heating/cooling process, respectively. From low- to intermediate-temperature phase, the space group changes from P21/c to Cmca, and the crystallographic axis being perpendicular to the layers is doubly together with the order-disorder transformation of (CH3)4N+ cations between inter-layers...
February 13, 2019: Chemistry: a European Journal
Lu Yin, Hongwei Jiang, Weiwei Zhao, Hui Li
Therapeutic hypothermia is a treatment method to reduce brain injuries after stroke, especially for cerebral ischemia. This study investigates in the temperature distribution of the head within selective brain cooling (SBC). Anatomically accurate geometries based on CT images of head and neck regions are used to develop the 3D geometry and physical model for the finite element modeling. Two cooling methods, the direct head surface cooling strategy and the combination cooling strategy of both head and neck, are evaluated to analyze the inducing hypothermia...
February 12, 2019: Medical & Biological Engineering & Computing
A P Luiz, D I MacDonald, S Santana-Varela, Q Millet, S Sikandar, J N Wood, E C Emery
The ability to detect environmental cold serves as an important survival tool. The sodium channels NaV 1.8 and NaV 1.9, as well as the TRP channel Trpm8, have been shown to contribute to cold sensation in mice. Surprisingly, transcriptional profiling shows that NaV 1.8/NaV 1.9 and Trpm8 are expressed in nonoverlapping neuronal populations. Here we have used in vivo GCaMP3 imaging to identify cold-sensing populations of sensory neurons in live mice. We find that ∼80% of neurons responsive to cold down to 1 °C do not express NaV 1...
February 12, 2019: Proceedings of the National Academy of Sciences of the United States of America
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