nitrofurazone

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Lanthanide metal-organic frameworks (LnMOFs) have substantial potential in luminescence due to their unique antenna effect. Nevertheless, the single emission is susceptible to pseudo-signals caused by external environmental conditions, which significantly threaten the accurate measurement of the concentration. In this case, we prepared a dual-emission fluorescent probe {Eux Tb1-x (NH2 -BDC)3 (DMF)4 ·2DMF}∞ (NH2 -BDC = Diaminoterephthalic acid, DMF = N,N-dimethylformamide). The stable dual-emission signal provides a superior signal output for detecting nitrofurazone (NFZ), which is detected by the probe with excellent fluorescence for 0-10 μM NFZ...

Marine periphytic ciliates play a pivotal role in shaping coastal ecosystems dynamics, thereby acting as robust biological indicators of aquatic ecosystem health and functionality. However, the understanding of the effects of veterinary antibiotics on composition and structure of periphytic ciliate communities remains limited. Therefore, this research investigates the influence of the veterinary antibiotic nitrofurazone on the community dynamics of marine periphytic ciliates through bioassay experiments conducted over a one-year cycle...

A very common reaction, N -benzylation of isatoic anhydride in the presence of sodium hydride base, produces byproducts. The yield of one of the byproducts was greater than that of the desired product; therefore, we identified the anonymous undisclosed structure of the byproduct using sequential spectroscopy methods and SC-XRD. This byproduct was found to be effective as a wound-healing and anti-inflammatory agent. The 10% formulation of byproduct and standard (nitrofurazone) showed complete wound closure with a large number of cell migrations within 16 days...

WLEDs have been widely used in lighting and display equipment due to their energy-saving and environment-friendly advantages, but it is still a great challenge to construct high-quality single-phase white light materials for the preparation of WLEDs. In this work, three Ln-MOFs (HNU-82-84) with the same structure were synthesized by assembling rare earth ions (Tb3+ , Eu3+ , La3+ ) and 4,4',4''-nitrilotribenzoic acid (H3 TCA) ligands. The structure and optical properties of the three compounds were investigated...

Recognition of the microbial cell's surface constituents' biophysical properties is an important research topic, allowing a better understanding of the cell's behaviour under different conditions. Atomic force microscopy (AFM) was employed in this study to analyse the basis of the nanomechanical changes in probiotic bacteria under nitrofurantoin, furazolidone, and nitrofurazone exposure. Recorded significant changes in the two Lactobacillus strains cells morphology, topography, and adhesion parameters resulted in the increase of the cells' longitude (up to 2...

Two-dimensional metal-organic framework (MOF) composites were produced by incorporating Fe-MOFs into reduced graphene oxide (rGO) nanosheets to form Fe-MOF/rGO composites by hydrothermal synthesis. SEM, TEM, XRD, XPS, and measurements of contact angles were used to characterize the composites. TEM studies revealed that the rod-like-shaped Fe-MOFs were extensively dispersed on the rGO sheets. Incorporating Fe-MOF into rGO significantly improves performance due to the large surface area, chemical stability, and high electrical conductivity...

Purpose: This study aimed to evaluate and analyze the efficacy and safety of low concentration (0.15%) hydrogen peroxide as nasopharyngeal lavage fluid in the treatment for nasopharyngeal carcinoma radiotherapy. Methods: Patients with nasopharyngeal carcinoma from Jiangxi cancer hospital were randomly divided into two cohorts. The training cohort ( n = 50) received low concentration (0.15%) hydrogen peroxide as nasopharyngeal lavage fluid in the treatment for nasopharyngeal carcinoma radiotherapy, and the control cohort ( n = 50) received 0...

Herein we report two 2D layered metal-organic rotaxane frameworks (MORFs), WUST-1 and WUST-2, constituted by a ternary host-guest complex based on cucurbit[8]uril (CB[8]) and an ( E )-1-methyl-4-[4-(pyridin-4-yl)styryl] pyridinium (G1) ligand, and different metal ions and auxiliary linkers. Both MORFs are stable in water and highly fluorescence emissive, and can selectively sense nitrofurazone with low detection limits.

A method was established for detecting the content of nitrofurazone (NFZ) by fluorescence quenching of N-Acetyl-L-Cysteine (NAC) coated cadmium telluride quantum dots (CdTe QDs). By means of transmission electron microscopy (TEM) and multispectral methods such as fluorescence and ultraviolet visible spectra (UV-vis), the synthesized CdTe QDs were characterized. The quantum yield (φ) of CdTe QDs was measured as 0.33 by reference method. The CdTe QDs had a better stability, the RSD of fluorescence intensity was 1...

The efficient removal of organic contaminants from wastewater is, nowadays, a prominent area of study due to its biological as well as environmental significance. Antibiotics are now found in wastewater because of their high use, which has become a source of aquatic pollution. These antibiotics have dangerous implications for people's health. Hence, effective pharmaceutical removal from wastewater and contaminated water bodies, especially the removal of antibiotics, is of major interest to global research organizations...

Catheter-associated urinary tract infections are one of the most common hospital-acquired infections. Encrustation formation results from infection of urease-producing bacteria and further complicates the situation. A typical sign of the initial onset of encrustation formation is the alkalization of the urine (pH up to 9-10). However, effective antibacterial strategies with high antimicrobial loading efficiency and pH-responsiveness of antimicrobial release are still lacking. In this study, we developed a poly(sulfobetaine methacrylate)-tannic acid (polySBMA-TA) hydrogel coating, which served as a universal, efficient, and responsive carrier for antimicrobials on urinary catheters...

Nitrofurazone (NFZ) is an antibiotic banned in many countries, as its residue seriously harms the human body. Herein, anti-NFZ aptamers were selected and identified based on the magnetic bead SELEX technique using a ssDNA library with a full length of 90 nucleotides (nt). Five full sequence candidate aptamers (NFZ8, NFZ24, NFZ28, NFZ34, and NFZ70) were obtained by secondary structure analysis. We optimized the entire sequence to obtain a truncated aptamer, a 16 nt sequence (NFZ8-1:5'-GTTCTATTGAAAAAAC-3') that showed the highest affinity for NFZ (Kd  = 76...

Surface enhanced Raman spectroscopy (SERS) has been widely studied and recognized as a powerful label-free technique for trace chemical analysis. However, its drawback in simultaneously identifying several molecular species has greatly limited its real-world applications. In this work, we reported a combination between SERS and independent component analysis (ICA) to detect several trace antibiotics which are commonly used in aquacultures, including malachite green, furazolidone, furaltadone hydrochloride, nitrofurantoin, and nitrofurazone...

Herein, we describe the synthesis of a new fluorescent d10 coordination polymer, [Zn2 (CFDA)2 (BPEP)]n ·nDMF (CP-1) under solvothermal reaction condition using zinc metal ion. In CP-1, Zn(II) ion along with CFDA and BPED ligand forms a 2-fold self-interpenetrated 3D coordination polymers. This CP-1 is characterized by the single crystal X-ray diffraction (SCXRD), powder X-ray diffraction (PXRD), infrared spectra, optical microscope image and thermogravimetric analysis and the framework is found to maintain its structural stability in different solvents...

The use of functional traits of a community as a method to measure its functional dynamics in response to environmental change has gained attention because trait-based approaches offer systematic opportunities to understand the interactions between species diversity and ecosystem function. However, the relationship between functional traits of periphytic protozoa and contamination of aquatic habitats with antibiotics is poorly understood. In this study, we investigated the influence of the antibiotic nitrofurazone on functional traits of marine periphytic protozoan fauna...

BACKGROUND: Antimicrobial resistance (AMR) is important in equine reproduction, as antimicrobials have historically been widely used in the management of breeding mares. However, evidence of the characteristics of AMR in uterine isolates is limited in the UK. The objective of this retrospective study was therefore to describe temporal changes in AMR patterns of bacteria isolated from the endometrium of Thoroughbred broodmares in south-east England between 2014 and 2020. METHOD: Endometrial swabs were processed for microbiology and antimicrobial susceptibility testing (AST)...

Although predation risk exists under natural conditions, its role is usually ignored when evaluating the ecotoxicity of environmental contaminants, and the interaction between predation risk and antibiotic ecotoxicity is not yet clear. To investigate the nonconsumptive effects (NCEs) of predation on the ecotoxicity evaluation of antibiotics, the median lethal concentration (LC50 ), relative population growth rate (RGR), and activities of three antioxidases were measured in the ciliate Paramecium jenningsi exposed to graded concentrations of the antibiotics nitrofurazone (NFZ) or erythromycin (ERY) in the presence or absence of a predator, i...

Semicarbazide (SEM), the metabolite of antibiotic nitrofurazone, is often used as the biomarker to determine the use of nitrofurazone. Frequent false-positive events of SEM have brought great trouble to the aquatic industry in international trade. In this paper, the situation of endogenous SEM in aquatic products was investigated, and the possible mechanism of amino acid conversion into SEM was studied by establishing a simulated oxidation system and a urea system. The results revealed the presence of endogenous SEM in the muscle tissue of shrimps, and the content of SEM ranged from 0...

In this work, a graphitic carbon nitride/gadolinium molybdate (g-C3 N4 /Gd2 MoO6 ) composite manufactured glassy carbon electrode (GCE) was used to detect nitrofurazone (NFZ) at the trace level. A quick and inexpensive electrochemical sensor for NFZ analysis is described in this paper. The material structure and properties were determined by scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, Fourier-transform infrared spectroscopy, and transmission electron microscopy. The GCE/g-C3 N4 /Gd2 MoO6 electrode was studied using cyclic voltammetry and amperometry...