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JOURNAL ARTICLE
Didier Brassard, Catherine Laramée, Véronique Provencher, Marie-Claude Vohl, Julie Robitaille, Simone Lemieux, Benoît Lamarche
BACKGROUND: There is very limited knowledge on the magnitude to which foods with low nutritive value constitute the diet of adults from the province of Quebec. The extent to which these foods impact cardiometabolic risk is also poorly documented. The objective was to assess the contribution of low nutritive value foods to total energy intake (E) and to examine associations with cardiometabolic risk factors among French-speaking adults from 5 administrative regions of the Province of Quebec...
August 29, 2019: Nutrition Journal
#22
JOURNAL ARTICLE
Stéphanie Harrison, Didier Brassard, Simone Lemieux, Benoît Lamarche
The 2019 revised version of Canada's Food Guide (CFG) recommends limiting the consumption of processed foods that are high in saturated fatty acids (SFA). Yet, the contributions of each CFG group to the total SFA intake of Canadians are not specifically known. The objectives of this study were to quantify the total SFA intake of Canadians, determine the sources of SFA consumed by Canadian adults, and identify potential differences in these sources. A nation representative sample from the Canadian Community Health Survey (CCHS - Nutrition 2015) was used for these analyses...
August 21, 2019: Nutrients
#23
JOURNAL ARTICLE
Jacynthe Lafrenière, Élise Carbonneau, Catherine Laramée, Louise Corneau, Julie Robitaille, Marie-Ève Labonté, Benoît Lamarche, Simone Lemieux
The objective of this study was to identify key elements from the 2007 Canada's Food Guide that should be included in a diet quality score aiming to reflect the risk of metabolic syndrome (MetS). Dietary intakes of 998 adults (mean age: 43.2 years, 50% women) were used to obtain the Canadian Healthy Eating Index 2007 (C-HEI 2007) and Alternative Healthy Eating Index 2010 (AHEI) scores, as well as a dietary pattern (DP) generated by the reduced rank regression (RRR) method. Based on these three scores, a modified version of the C-HEI 2007 (Modified C-HEI) was then proposed...
July 14, 2019: Nutrients
#24
JOURNAL ARTICLE
Hanane Moussa, Molière Nguile-Makao, Karine Robitaille, Marie-Hélène Guertin, Janie Allaire, Jean-François Pelletier, Xavier Moreel, Nikunj Gevariya, Caroline Diorio, Patrice Desmeules, Bernard Têtu, Benoît Lamarche, Pierre Julien, Vincent Fradet
Dietary omega-3 fatty acids (ω3), particularly long-chain ω3 (LCω3), have protective effects against prostate cancer (PCa) in experimental studies. Observational studies are conflicting, possibly because of the biomarker used. This study aimed at evaluating associations between grade reclassification and ω3 levels assessed in prostatic tissue, red blood cells (RBC), and diet. We conducted a validation cross-sectional study nested within a phase II clinical trial. We identified 157 men diagnosed with low-risk PCa who underwent a first active surveillance repeat prostate biopsy session...
July 16, 2019: Nutrients
#25
RANDOMIZED CONTROLLED TRIAL
Shatha S Hammad, Peter Eck, Jyoti Sihag, Xiang Chen, Philip W Connelly, Benoît Lamarche, Patrick Couture, Valérie Guay, Julie Maltais-Giguère, Sheila G West, Penny M Kris-Etherton, Kate J Bowen, David J A Jenkins, Carla G Taylor, Danielle Perera, Angela Wilson, Sandra Castillo, Peter Zahradka, Peter J H Jones
BACKGROUND: Different fatty acids (FAs) can vary in their obesogenic effect, and genetic makeup can contribute to fat deposition in response to dietary FA composition. However, the antiobesogenic effects of the interactions between dietary MUFAs and genetics have scarcely been tested in intervention studies. OBJECTIVE: We evaluated the overall (primary outcome) and genetically modulated (secondary outcome) response in body weight and fat mass to different levels of MUFA consumption...
October 1, 2019: Journal of Nutrition
#26
JOURNAL ARTICLE
Arne Astrup, Hanne Cs Bertram, Jean-Philippe Bonjour, Lisette Cp de Groot, Marcia C de Oliveira Otto, Emma L Feeney, Manohar L Garg, Ian Givens, Frans J Kok, Ronald M Krauss, Benoît Lamarche, Jean-Michel Lecerf, Philippe Legrand, Michelle McKinley, Renata Micha, Marie-Caroline Michalski, Dariush Mozaffarian, Sabita S Soedamah-Muthu
No abstract text is available yet for this article.
July 3, 2019: BMJ: British Medical Journal
#27
JOURNAL ARTICLE
Bénédicte L Tremblay, Frédéric Guénard, Benoît Lamarche, Louis Pérusse, Marie-Claude Vohl
Variability in plasma carotenoids may be attributable to several factors including genetic variants and lipid profile. Until now, the impact of DNA methylation on this variability has not been widely studied. Weighted gene correlation network analysis (WGCNA) is a systems biology method used for finding gene clusters (modules) with highly correlated methylation levels and for relating them to phenotypic traits. The objective of the present study was to examine the role of DNA methylation in the relationship between plasma total carotenoid concentrations and lipid profile using WGCNA in 48 healthy subjects...
June 4, 2019: Nutrients
#28
JOURNAL ARTICLE
Janie Allaire, Cécile Vors, William S Harris, Kristina Harris Jackson, André Tchernof, Patrick Couture, Benoît Lamarche
Studies show that the reduction in serum triglyceride concentrations with long-chain omega-3 fatty acid supplementation is highly variable among individuals. The objectives of this study were to compare the proportions of individuals whose triglyceride concentrations are lowered after high-dose docosahexaenoic (DHA) and eicosapentaenoic acid (EPA), and to identify predictors of the response to both modalities. In a double-blind controlled crossover study, 154 men and women were randomized to three supplemented phases of 10 weeks each: 1) 2...
March 11, 2019: British Journal of Nutrition
#29
JOURNAL ARTICLE
Andrea M Brennan, Andrew G Day, Theresa E Cowan, Gregory J Clarke, Benoit Lamarche, Robert Ross
PURPOSE: (1) Determine the effect of exercise amount and intensity on the proportion of adipose tissue (AT) responses likely, very likely, and unlikely above the minimal clinically important difference (MCID); and (2) Examine whether clinically meaningful anthropometric changes reflect individual AT responses above the MCID. METHODS: Men (n=41) and women (n=62) (52.7 ± 7.6 years) were randomized to control (N=20); low amount low intensity (LALI, N=24); high amount low intensity (HALI, N=30); and high amount high intensity (HAHI, N=29) exercise for 24 weeks...
February 15, 2019: Medicine and Science in Sports and Exercise
#30
JOURNAL ARTICLE
Kate J Bowen, Penny M Kris-Etherton, Sheila G West, Jennifer A Fleming, Philip W Connelly, Benoît Lamarche, Patrick Couture, David J A Jenkins, Carla G Taylor, Peter Zahradka, Shatha S Hammad, Jyoti Sihag, Xiang Chen, Valérie Guay, Julie Maltais-Giguère, Danielle Perera, Angela Wilson, Sandra Castillo San Juan, Julia Rempel, Peter J H Jones
BACKGROUND: Novel oils high in monounsaturated fatty acids (MUFAs) and low in saturated fatty acids (SFAs) are an alternative to partially hydrogenated oils high in trans-unsaturated fatty acids. There is widespread use of high-MUFA oils across the food industry; however, limited knowledge of their cardiovascular impact exists. OBJECTIVES: We investigated the effects of diets containing canola oil, high-oleic acid canola oil (HOCO), and a control oil blend (diet formulated to emulate a Western fat profile) on lipids, lipoproteins, and apolipoproteins (apos), as secondary outcomes of the trial...
March 1, 2019: Journal of Nutrition
#31
JOURNAL ARTICLE
Bénédicte L Tremblay, Frédéric Guénard, Benoît Lamarche, Louis Pérusse, Marie-Claude Vohl
Metabolites are of great importance for understanding the pathogenesis of several diseases. Understanding the genetic contribution to metabolite concentrations may provide insights into mechanisms of complex diseases. Several studies have investigated heritability of metabolites but none investigated potential influences of genetic and environmental factors on the relationship between metabolites and cardiometabolic (CM) risk factors. Thus, we tested the hypothesis that both genetic and common environmental effects contribute to the variance of plasma metabolite concentrations and that shared genetic and environmental effects explain their phenotypic correlations with CM risk factors...
January 2019: Nutrition Research
#32
JOURNAL ARTICLE
David J A Jenkins, Cyril W C Kendall, Benoît Lamarche, Monica S Banach, Korbua Srichaikul, Edward Vidgen, Sandy Mitchell, Tina Parker, Stephanie Nishi, Balachandran Bashyam, Russell J de Souza, Christopher Ireland, Sathish C Pichika, Joseph Beyene, John L Sievenpiper, Robert G Josse
In contrast to statements made in the above paper, measurements of waist and hip circumference were in fact available.
March 2019: Diabetologia
#33
JOURNAL ARTICLE
Didier Brassard, Catherine Laramée, Louise Corneau, Catherine Bégin, Mathieu Bélanger, Luigi Bouchard, Charles Couillard, Sophie Desroches, Julie Houle, Marie-France Langlois, Véronique Provencher, Rémi Rabasa-Lhoret, Marie-Claude Vohl, Julie Robitaille, Simone Lemieux, Benoît Lamarche
BACKGROUND: Regular monitoring of the population's food and nutrient intake is essential to develop effective nutrition-focused public health policies. The aim of this study was to provide dietary intake estimates using an age- and sex-representative sample of French-speaking adults with Internet access from 5 administrative regions in the province of Quebec, Canada. METHODS: PRÉDicteurs Individuels, Sociaux et Environnementaux (PREDISE) is a multicentre cross-sectional study that used a Web-based approach to collect individual, social, and environmental data on factors associated with adherence to dietary recommendations...
December 2018: Canadian Journal of Cardiology
#34
JOURNAL ARTICLE
Lisa Pennells, Stephen Kaptoge, Angela Wood, Mike Sweeting, Xiaohui Zhao, Ian White, Stephen Burgess, Peter Willeit, Thomas Bolton, Karel G M Moons, Yvonne T van der Schouw, Randi Selmer, Kay-Tee Khaw, Vilmundur Gudnason, Gerd Assmann, Philippe Amouyel, Veikko Salomaa, Mika Kivimaki, Børge G Nordestgaard, Michael J Blaha, Lewis H Kuller, Hermann Brenner, Richard F Gillum, Christa Meisinger, Ian Ford, Matthew W Knuiman, Annika Rosengren, Debbie A Lawlor, Henry Völzke, Cyrus Cooper, Alejandro Marín Ibañez, Edoardo Casiglia, Jussi Kauhanen, Jackie A Cooper, Beatriz Rodriguez, Johan Sundström, Elizabeth Barrett-Connor, Rachel Dankner, Paul J Nietert, Karina W Davidson, Robert B Wallace, Dan G Blazer, Cecilia Björkelund, Chiara Donfrancesco, Harlan M Krumholz, Aulikki Nissinen, Barry R Davis, Sean Coady, Peter H Whincup, Torben Jørgensen, Pierre Ducimetiere, Maurizio Trevisan, Gunnar Engström, Carlos J Crespo, Tom W Meade, Marjolein Visser, Daan Kromhout, Stefan Kiechl, Makoto Daimon, Jackie F Price, Agustin Gómez de la Cámara, J Wouter Jukema, Benoît Lamarche, Altan Onat, Leon A Simons, Maryam Kavousi, Yoav Ben-Shlomo, John Gallacher, Jacqueline M Dekker, Hisatomi Arima, Nawar Shara, Robert W Tipping, Ronan Roussel, Eric J Brunner, Wolfgang Koenig, Masaru Sakurai, Jelena Pavlovic, Ron T Gansevoort, Dorothea Nagel, Uri Goldbourt, Elizabeth L M Barr, Luigi Palmieri, Inger Njølstad, Shinichi Sato, W M Monique Verschuren, Cherian V Varghese, Ian Graham, Oyere Onuma, Philip Greenland, Mark Woodward, Majid Ezzati, Bruce M Psaty, Naveed Sattar, Rod Jackson, Paul M Ridker, Nancy R Cook, Ralph B D'Agostino, Simon G Thompson, John Danesh, Emanuele Di Angelantonio
AIMS: There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four algorithms recommended by primary prevention guidelines, before and after 'recalibration', a method that adapts risk algorithms to take account of differences in the risk characteristics of the populations being studied. METHODS AND RESULTS: Using individual-participant data on 360 737 participants without CVD at baseline in 86 prospective studies from 22 countries, we compared the Framingham risk score (FRS), Systematic COronary Risk Evaluation (SCORE), pooled cohort equations (PCE), and Reynolds risk score (RRS)...
February 14, 2019: European Heart Journal
#35
JOURNAL ARTICLE
Theresa E Cowan, Andrea M Brennan, Paula J Stotz, John Clarke, Benoit Lamarche, Robert Ross
OBJECTIVE: To determine the effects of exercise amount (kilocalories per session) and intensity (percent of maximal oxygen consumption [% VO2 peak]) on adipose tissue (AT) and skeletal muscle (SM) in adults with abdominal obesity. METHODS: Participants (n = 103; 52.7 ± 7.6 years) were randomized to the following groups: control; low-amount, low-intensity exercise (180 kcal/session [women] and 300 kcal/session [men] at 50% VO2 peak); high-amount, low-intensity exercise (HALI; 360 kcal/session [women] and 600 kcal/session [men] at 50% VO2 peak); or high-amount, high-intensity exercise (HAHI; 360 kcal/session [women] and 600 kcal/session [men] at 75% VO2 peak) for 24 weeks...
November 2018: Obesity
#36
JOURNAL ARTICLE
Stéphanie Harrison, Élise Carbonneau, Denis Talbot, Simone Lemieux, Benoît Lamarche
BACKGROUND: Studies have shown that the majority of endurance athletes do not achieve the minimal recommended carbohydrate (CHO) intake of 6 g/kg of body weight (BW), with potentially negative impacts on recovery and performance. The purpose of this study was to develop and validate a rapid and easy to use dietary screener to identify athletes who do and do not achieve a CHO intake > 6 g/kg BW in the context of endurance sports. METHODS: The dietary screener was developed using multiple logistic regression modeling of data from a sample of 1571 non-athlete adults (826 women and 745 men, mean age 44...
September 14, 2018: Journal of the International Society of Sports Nutrition
#37
RANDOMIZED CONTROLLED TRIAL
Brittany P Hammond, Paula J Stotz, Andrea M Brennan, Benoît Lamarche, Andrew G Day, Robert Ross
PURPOSE: This study aimed to determine the magnitude of exercise-induced individual variability for waist circumference (WC) and body weight change after accounting for biological variability and measurement error. Determinants of response variability were also considered. METHODS: Participants (53 ± 7.5 yr) were 181 adults (61% women) with abdominal obesity randomized to the following: control; low-amount, low-intensity exercise (LALI); high-amount, low-intensity exercise (HALI); or high-amount, high-intensity exercise (HAHI) for 24 wk...
February 2019: Medicine and Science in Sports and Exercise
#38
JOURNAL ARTICLE
Didier Brassard, Simone Lemieux, Amélie Charest, Annie Lapointe, Patrick Couture, Marie-Ève Labonté, Benoît Lamarche
Traditional food frequency questionnaires (FFQs) are influenced by systematic error, but web-based FFQ (WEB-FFQs) may mitigate this source of error. The objective of this study was to compare the accuracy of interview-based and web-based FFQs to assess energy requirements (mERs). The mER was measured in a series of controlled feeding trials in which participants daily received all foods and caloric drinks to maintain stable body weight over 4 to 6 weeks. FFQs assessing dietary intakes and hence mean energy intake were either interviewer-administered by a registered dietitian (IA-FFQ, n = 127; control method) or self-administered using a web-based platform (WEB-FFQ, n = 200; test method), on a single occasion...
September 12, 2018: Nutrients
#39
JOURNAL ARTICLE
Jacynthe Lafrenière, Catherine Laramée, Julie Robitaille, Benoît Lamarche, Simone Lemieux
OBJECTIVES: A new, web-based, 24-h recall (R24 W) was developed and programmed to assess adherence to Canadian dietary guidelines by automatically generating the Canadian Healthy Eating Index 2007 (C-HEI 2007). The aim of the present study was to determine the relative validity of the R24 W in terms of its ability to generate C-HEI 2007 scores that match those derived from a food record (FR). METHODS: A total of 57 women and 50 men filled a 3-d FR and three 24-h food recalls with the R24 W...
May 24, 2018: Nutrition
#40
JOURNAL ARTICLE
Janie Allaire, Denis Talbot, Patrick Couture, André Tchernof, Peter J H Jones, Penny Kris-Etherton, Sheila G West, Philip W Connelly, David J A Jenkins, Benoît Lamarche
The purpose of this study was to examine how using the mean of two consecutive measurements vs. one measurement post-treatment influences the sample size required to detect changes in cardiometabolic risk factors in dietary studies. For a given statistical power, using the mean of two measurements taken on consecutive days post-treatment instead of a single measurement significantly reduces the sample size required to observe changes in triglyceride, total apolipoprotein B100, and C-reactive protein concentrations in the context of a supplementation study...
July 31, 2018: European Journal of Clinical Nutrition
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