keyword
https://read.qxmd.com/read/37788043/testing-the-effect-of-a-smartphone-app-on-hospital-admissions-and-sedentary-behavior-in-cardiac-rehabilitation-participants-todo-cr-randomized-controlled-trial
#21
JOURNAL ARTICLE
Kacie Patterson, Rachel Davey, Richard Keegan, Theo Niyonsenga, Itismita Mohanty, Sarah Bowen, Elizabeth Regan, Michelle Lander, Sander van Berlo, Nicole Freene
BACKGROUND: People with coronary heart disease are at an increased risk of morbidity and mortality even if they attend cardiac rehabilitation. High sedentary behavior levels potentially contribute to this morbidity. Smartphone apps may be feasible to facilitate sedentary behavior reductions and lead to reduced health care use. OBJECTIVE: We aimed to test the effect of a sedentary behavior change smartphone app (Vire app and ToDo-CR program) as an adjunct to cardiac rehabilitation on hospital admissions and emergency department (ED) presentations over 12 months...
October 3, 2023: JMIR MHealth and UHealth
https://read.qxmd.com/read/37768028/the-anticancer-cytotoxic-effect-of-a-novel-gallic-acid-derivative-in-non-small-cell-lung-carcinoma-a549-cells-and-peripheral-blood-mononuclear-cells-from-healthy-individuals-and-lung-cancer-patients
#22
JOURNAL ARTICLE
Shohreh Jafarinejad, William H C Martin, Bayan Abu Ras, Mohammad Isreb, Badie Jacob, Abid Aziz, Zahra Adoul, Ruby Lagnado, Richard D Bowen, Mojgan Najafzadeh
Gallic acid (GA) is a naturally occurring polyphenol with a strong antioxidant capacity. GA stimulates the apoptosis of cancer cells, thereby suppressing cancer cell invasion. However, the low oral permeability of GA limits its therapeutic use. In order to enhance the antioxidant capacity and oral permeability of GA, a series of compounds analogous to GA were synthesized: 4-methoxybenzenesulfonamide (MBS), 3,4-dimethoxybenzenesulfonamide (DMBS) and 3,4,5-trimethoxybenzenesulfonamide (TMBS). In the new compounds, hydroxyl groups were replaced with various numbers of methoxy groups (stronger electron-donating groups), to increase hydrophobicity and oral permeability compared to GA...
September 28, 2023: BioFactors
https://read.qxmd.com/read/37726935/remission-of-severe-myasthenia-gravis-after-autologous-stem-cell-transplantation
#23
JOURNAL ARTICLE
Monica I Schlatter, Soumya S Yandamuri, Kevin C O'Connor, Richard J Nowak, Minh C Pham, Abeer H Obaid, Callee Redman, Marie Provost, Peter A McSweeney, Michael L Pearlman, Michael T Tees, James D Bowen, Richard A Nash, George E Georges
OBJECTIVE: Myasthenia gravis (MG) is an autoantibody-mediated neuromuscular junction disorder involving the acetylcholine receptors on the motor endplate. The safety and response to high-dose chemotherapy (HDIT) and autologous hematopoietic cell transplantation (HCT) were assessed in a patient with severe refractory MG. METHODS: As part of a pilot study of HDIT/HCT for patients with treatment-resistant autoimmune neurological disorders, a patient with severe refractory MG underwent treatment...
September 19, 2023: Annals of Clinical and Translational Neurology
https://read.qxmd.com/read/37726270/evolutionary-origin-of-genomic%C3%A2-structural-variations-in-domestic-yaks
#24
JOURNAL ARTICLE
Xinfeng Liu, Wenyu Liu, Johannes A Lenstra, Zeyu Zheng, Xiaoyun Wu, Jiao Yang, Bowen Li, Yongzhi Yang, Qiang Qiu, Hongyu Liu, Kexin Li, Chunnian Liang, Xian Guo, Xiaoming Ma, Richard J Abbott, Minghui Kang, Ping Yan, Jianquan Liu
Yak has been subject to natural selection, human domestication and interspecific introgression during its evolution. However, genetic variants favored by each of these processes have not been distinguished previously. We constructed a graph-genome for 47 genomes of 7 cross-fertile bovine species. This allowed detection of 57,432 high-resolution structural variants (SVs) within and across the species, which were genotyped in 386 individuals. We distinguished the evolutionary origins of diverse SVs in domestic yaks by phylogenetic analyses...
September 19, 2023: Nature Communications
https://read.qxmd.com/read/37693180/a-general-purpose-self-supervised-model-for-computational-pathology
#25
Richard J Chen, Tong Ding, Ming Y Lu, Drew F K Williamson, Guillaume Jaume, Bowen Chen, Andrew Zhang, Daniel Shao, Andrew H Song, Muhammad Shaban, Mane Williams, Anurag Vaidya, Sharifa Sahai, Lukas Oldenburg, Luca L Weishaupt, Judy J Wang, Walt Williams, Long Phi Le, Georg Gerber, Faisal Mahmood
Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem in which the large-scale image resolutions of WSIs and the enormous diversity of morphological phenotypes preclude large-scale data annotation. Current efforts have proposed using pretrained image encoders with either transfer learning from natural image datasets or self-supervised pretraining on publicly-available histopathology datasets, but have not been extensively developed and evaluated across diverse tissue types at scale...
August 29, 2023: ArXiv
https://read.qxmd.com/read/37595238/azimuthal-correlations-within-exclusive-dijets-with-large-momentum-transfer-in-photon-lead-collisions
#26
JOURNAL ARTICLE
A Tumasyan, W Adam, T Bergauer, M Dragicevic, A Escalante Del Valle, R Frühwirth, M Jeitler, N Krammer, L Lechner, D Liko, I Mikulec, F M Pitters, N Rad, J Schieck, R Schöfbeck, M Spanring, S Templ, W Waltenberger, C-E Wulz, M Zarucki, M R Darwish, E A De Wolf, D Di Croce, T Janssen, T Kello, A Lelek, M Pieters, H Rejeb Sfar, H Van Haevermaet, P Van Mechelen, S Van Putte, N Van Remortel, F Blekman, E S Bols, S S Chhibra, J D'Hondt, J De Clercq, D Lontkovskyi, S Lowette, I Marchesini, S Moortgat, A Morton, D Müller, Q Python, S Tavernier, W Van Doninck, P Van Mulders, D Beghin, B Bilin, B Clerbaux, G De Lentdecker, B Dorney, L Favart, A Grebenyuk, A K Kalsi, I Makarenko, L Moureaux, L Pétré, A Popov, N Postiau, E Starling, L Thomas, C Vander Velde, P Vanlaer, D Vannerom, L Wezenbeek, T Cornelis, D Dobur, M Gruchala, I Khvastunov, M Niedziela, C Roskas, K Skovpen, M Tytgat, W Verbeke, B Vermassen, M Vit, G Bruno, F Bury, C Caputo, P David, C Delaere, M Delcourt, I S Donertas, A Giammanco, V Lemaitre, K Mondal, J Prisciandaro, A Taliercio, M Teklishyn, P Vischia, S Wertz, S Wuyckens, G A Alves, C Hensel, A Moraes, W L Aldá Júnior, E Belchior Batista Das Chagas, H Brandao Malbouisson, W Carvalho, J Chinellato, E Coelho, E M Da Costa, G G Da Silveira, D De Jesus Damiao, S Fonseca De Souza, J Martins, D Matos Figueiredo, M Medina Jaime, C Mora Herrera, L Mundim, H Nogima, P Rebello Teles, L J Sanchez Rosas, A Santoro, S M Silva Do Amaral, A Sznajder, M Thiel, F Torres Da Silva De Araujo, A Vilela Pereira, C A Bernardes, L Calligaris, T R Fernandez Perez Tomei, E M Gregores, D S Lemos, P G Mercadante, S F Novaes, Sandra S Padula, A Aleksandrov, G Antchev, I Atanassov, R Hadjiiska, P Iaydjiev, M Misheva, M Rodozov, M Shopova, G Sultanov, A Dimitrov, T Ivanov, L Litov, B Pavlov, P Petkov, A Petrov, T Cheng, W Fang, Q Guo, H Wang, L Yuan, M Ahmad, G Bauer, Z Hu, Y Wang, K Yi, E Chapon, G M Chen, H S Chen, M Chen, T Javaid, A Kapoor, D Leggat, H Liao, Z-A Liu, R Sharma, A Spiezia, J Tao, J Thomas-Wilsker, J Wang, H Zhang, S Zhang, J Zhao, A Agapitos, Y Ban, C Chen, Q Huang, A Levin, Q Li, M Lu, X Lyu, Y Mao, S J Qian, D Wang, Q Wang, J Xiao, Z You, X Gao, M Xiao, C Avila, A Cabrera, C Florez, J Fraga, A Sarkar, M A Segura Delgado, J Jaramillo, J Mejia Guisao, F Ramirez, J D Ruiz Alvarez, C A Salazar González, N Vanegas Arbelaez, D Giljanovic, N Godinovic, D Lelas, I Puljak, Z Antunovic, M Kovac, T Sculac, V Brigljevic, D Ferencek, D Majumder, M Roguljic, A Starodumov, T Susa, M W Ather, A Attikis, E Erodotou, A Ioannou, G Kole, M Kolosova, S Konstantinou, J Mousa, C Nicolaou, F Ptochos, P A Razis, H Rykaczewski, H Saka, D Tsiakkouri, M Finger, M Finger, A Kveton, J Tomsa, E Ayala, E Carrera Jarrin, H Abdalla, A A Abdelalim, Y Assran, A Lotfy, M A Mahmoud, S Bhowmik, A Carvalho Antunes De Oliveira, R K Dewanjee, K Ehataht, M Kadastik, M Raidal, C Veelken, P Eerola, L Forthomme, H Kirschenmann, K Osterberg, M Voutilainen, E Brücken, F Garcia, J Havukainen, V Karimäki, M S Kim, R Kinnunen, T Lampén, K Lassila-Perini, S Lehti, T Lindén, H Siikonen, E Tuominen, J Tuominiemi, P Luukka, T Tuuva, C Amendola, M Besancon, F Couderc, M Dejardin, D Denegri, J L Faure, F Ferri, S Ganjour, A Givernaud, P Gras, G Hamel de Monchenault, P Jarry, B Lenzi, E Locci, J Malcles, J Rander, A Rosowsky, M Ö Sahin, A Savoy-Navarro, M Titov, G B Yu, S Ahuja, F Beaudette, M Bonanomi, A Buchot Perraguin, P Busson, C Charlot, O Davignon, B Diab, G Falmagne, R Granier de Cassagnac, A Hakimi, I Kucher, A Lobanov, C Martin Perez, M Nguyen, C Ochando, P Paganini, J Rembser, R Salerno, J B Sauvan, Y Sirois, A Zabi, A Zghiche, J-L Agram, J Andrea, D Bloch, G Bourgatte, J-M Brom, E C Chabert, C Collard, J-C Fontaine, D Gelé, U Goerlach, C Grimault, A-C Le Bihan, P Van Hove, E Asilar, S Beauceron, C Bernet, G Boudoul, C Camen, A Carle, N Chanon, D Contardo, P Depasse, H El Mamouni, J Fay, S Gascon, M Gouzevitch, B Ille, Sa Jain, I B Laktineh, H Lattaud, A Lesauvage, M Lethuillier, L Mirabito, K Shchablo, L Torterotot, G Touquet, M Vander Donckt, S Viret, I Bagaturia, Z Tsamalaidze, L Feld, K Klein, M Lipinski, D Meuser, A Pauls, M P Rauch, J Schulz, M Teroerde, D Eliseev, M Erdmann, P Fackeldey, B Fischer, S Ghosh, T Hebbeker, K Hoepfner, H Keller, L Mastrolorenzo, M Merschmeyer, A Meyer, G Mocellin, S Mondal, S Mukherjee, D Noll, A Novak, T Pook, A Pozdnyakov, Y Rath, H Reithler, J Roemer, A Schmidt, S C Schuler, A Sharma, S Wiedenbeck, S Zaleski, C Dziwok, G Flügge, W Haj Ahmad, O Hlushchenko, T Kress, A Nowack, C Pistone, O Pooth, D Roy, H Sert, A Stahl, T Ziemons, H Aarup Petersen, M Aldaya Martin, P Asmuss, I Babounikau, S Baxter, O Behnke, A Bermúdez Martínez, A A Bin Anuar, K Borras, V Botta, D Brunner, A Campbell, A Cardini, P Connor, S Consuegra Rodríguez, V Danilov, A De Wit, M M Defranchis, L Didukh, D Domínguez Damiani, G Eckerlin, D Eckstein, L I Estevez Banos, E Gallo, A Geiser, A Giraldi, A Grohsjean, M Guthoff, A Harb, A Jafari, N Z Jomhari, A Kasem, M Kasemann, H Kaveh, C Kleinwort, J Knolle, D Krücker, W Lange, T Lenz, J Lidrych, K Lipka, W Lohmann, T Madlener, R Mankel, I-A Melzer-Pellmann, J Metwally, A B Meyer, M Meyer, M Missiroli, J Mnich, A Mussgiller, V Myronenko, Y Otarid, D Pérez Adán, S K Pflitsch, D Pitzl, A Raspereza, A Saggio, A Saibel, M Savitskyi, V Scheurer, C Schwanenberger, A Singh, R E Sosa Ricardo, N Tonon, O Turkot, A Vagnerini, M Van De Klundert, R Walsh, D Walter, Y Wen, K Wichmann, C Wissing, S Wuchterl, O Zenaiev, R Zlebcik, R Aggleton, S Bein, L Benato, A Benecke, K De Leo, T Dreyer, A Ebrahimi, M Eich, F Feindt, A Fröhlich, C Garbers, E Garutti, P Gunnellini, J Haller, A Hinzmann, A Karavdina, G Kasieczka, R Klanner, R Kogler, V Kutzner, J Lange, T Lange, A Malara, C E N Niemeyer, A Nigamova, K J Pena Rodriguez, O Rieger, P Schleper, S Schumann, J Schwandt, D Schwarz, J Sonneveld, H Stadie, G Steinbrück, B Vormwald, I Zoi, J Bechtel, T Berger, E Butz, R Caspart, T Chwalek, W De Boer, A Dierlamm, A Droll, K El Morabit, N Faltermann, K Flöh, M Giffels, A Gottmann, F Hartmann, C Heidecker, U Husemann, I Katkov, P Keicher, R Koppenhöfer, S Maier, M Metzler, S Mitra, Th Müller, M Musich, G Quast, K Rabbertz, J Rauser, D Savoiu, D Schäfer, M Schnepf, M Schröder, D Seith, I Shvetsov, H J Simonis, R Ulrich, M Wassmer, M Weber, R Wolf, S Wozniewski, G Anagnostou, P Asenov, G Daskalakis, T Geralis, A Kyriakis, G Paspalaki, A Stakia, M Diamantopoulou, D Karasavvas, G Karathanasis, P Kontaxakis, C K Koraka, A Manousakis-Katsikakis, A Panagiotou, I Papavergou, N Saoulidou, K Theofilatos, E Tziaferi, K Vellidis, E Vourliotis, G Bakas, K Kousouris, I Papakrivopoulos, G Tsipolitis, A Zacharopoulou, I Evangelou, C Foudas, P Gianneios, P Katsoulis, P Kokkas, K Manitara, N Manthos, I Papadopoulos, J Strologas, M Bartók, M Csanád, M M A Gadallah, S Lökös, P Major, K Mandal, A Mehta, G Pásztor, O Surányi, G I Veres, G Bencze, C Hajdu, D Horvath, F Sikler, V Veszpremi, G Vesztergombi, S Czellar, J Karancsi, J Molnar, Z Szillasi, D Teyssier, P Raics, Z L Trocsanyi, B Ujvari, T Csorgo, F Nemes, T Novak, S Choudhury, J R Komaragiri, D Kumar, L Panwar, P C Tiwari, S Bansal, S B Beri, V Bhatnagar, G Chaudhary, S Chauhan, N Dhingra, R Gupta, A Kaur, S Kaur, P Kumari, M Meena, K Sandeep, S Sharma, J B Singh, A K Virdi, A Ahmed, A Bhardwaj, B C Choudhary, R B Garg, M Gola, S Keshri, A Kumar, M Naimuddin, P Priyanka, K Ranjan, A Shah, M Bharti, R Bhattacharya, S Bhattacharya, D Bhowmik, S Dutta, S Ghosh, B Gomber, M Maity, S Nandan, P Palit, P K Rout, G Saha, B Sahu, S Sarkar, M Sharan, B Singh, S Thakur, P K Behera, S C Behera, P Kalbhor, A Muhammad, R Pradhan, P R Pujahari, A Sharma, A K Sikdar, D Dutta, V Kumar, K Naskar, P K Netrakanti, L M Pant, P Shukla, T Aziz, M A Bhat, S Dugad, R Kumar Verma, G B Mohanty, U Sarkar, S Banerjee, S Bhattacharya, S Chatterjee, R Chudasama, M Guchait, S Karmakar, S Kumar, G Majumder, K Mazumdar, S Mukherjee, D Roy, S Bahinipati, D Dash, C Kar, P Mal, T Mishra, V K Muraleedharan Nair Bindhu, A Nayak, N Sur, S K Swain, S Dube, B Kansal, S Pandey, A Rane, A Rastogi, S Sharma, H Bakhshiansohi, M Zeinali, S Chenarani, S M Etesami, M Khakzad, M Mohammadi Najafabadi, M Felcini, M Grunewald, M Abbrescia, R Aly, C Aruta, A Colaleo, D Creanza, N De Filippis, M De Palma, A Di Florio, A Di Pilato, W Elmetenawee, L Fiore, A Gelmi, M Gul, G Iaselli, M Ince, S Lezki, G Maggi, M Maggi, I Margjeka, V Mastrapasqua, J A Merlin, S My, S Nuzzo, A Pompili, G Pugliese, A Ranieri, G Selvaggi, L Silvestris, F M Simone, R Venditti, P Verwilligen, G Abbiendi, C Battilana, D Bonacorsi, L Borgonovi, S Braibant-Giacomelli, R Campanini, P Capiluppi, A Castro, F R Cavallo, C Ciocca, M Cuffiani, G M Dallavalle, T Diotalevi, F Fabbri, A Fanfani, E Fontanesi, P Giacomelli, L Giommi, C Grandi, L Guiducci, F Iemmi, S Lo Meo, S Marcellini, G Masetti, F L Navarria, A Perrotta, F Primavera, A M Rossi, T Rovelli, G P Siroli, N Tosi, S Albergo, S Costa, A Di Mattia, R Potenza, A Tricomi, C Tuve, G Barbagli, A Cassese, R Ceccarelli, V Ciulli, C Civinini, R D'Alessandro, F Fiori, E Focardi, G Latino, P Lenzi, M Lizzo, M Meschini, S Paoletti, R Seidita, G Sguazzoni, L Viliani, L Benussi, S Bianco, D Piccolo, M Bozzo, F Ferro, R Mulargia, E Robutti, S Tosi, A Benaglia, A Beschi, F Brivio, F Cetorelli, V Ciriolo, F De Guio, M E Dinardo, P Dini, S Gennai, A Ghezzi, P Govoni, L Guzzi, M Malberti, S Malvezzi, A Massironi, D Menasce, F Monti, L Moroni, M Paganoni, D Pedrini, S Ragazzi, T Tabarelli de Fatis, D Valsecchi, D Zuolo, S Buontempo, N Cavallo, A De Iorio, F Fabozzi, F Fienga, A O M Iorio, L Lista, S Meola, P Paolucci, B Rossi, C Sciacca, P Azzi, N Bacchetta, D Bisello, P Bortignon, A Bragagnolo, R Carlin, P Checchia, P De Castro Manzano, T Dorigo, F Gasparini, U Gasparini, S Y Hoh, L Layer, M Margoni, A T Meneguzzo, M Presilla, P Ronchese, R Rossin, F Simonetto, G Strong, M Tosi, H Yarar, M Zanetti, P Zotto, A Zucchetta, G Zumerle, C Aime, A Braghieri, S Calzaferri, D Fiorina, P Montagna, S P Ratti, V Re, M Ressegotti, C Riccardi, P Salvini, I Vai, P Vitulo, M Biasini, G M Bilei, D Ciangottini, L Fanò, P Lariccia, G Mantovani, V Mariani, M Menichelli, F Moscatelli, A Piccinelli, A Rossi, A Santocchia, D Spiga, T Tedeschi, K Androsov, P Azzurri, G Bagliesi, V Bertacchi, L Bianchini, T Boccali, R Castaldi, M A Ciocci, R Dell'Orso, M R Di Domenico, S Donato, L Giannini, A Giassi, M T Grippo, F Ligabue, E Manca, G Mandorli, A Messineo, F Palla, G Ramirez-Sanchez, A Rizzi, G Rolandi, S Roy Chowdhury, A Scribano, N Shafiei, P Spagnolo, R Tenchini, G Tonelli, N Turini, A Venturi, P G Verdini, F Cavallari, M Cipriani, D Del Re, E Di Marco, M Diemoz, E Longo, P Meridiani, G Organtini, F Pandolfi, R Paramatti, C Quaranta, S Rahatlou, C Rovelli, F Santanastasio, L Soffi, R Tramontano, N Amapane, R Arcidiacono, S Argiro, M Arneodo, N Bartosik, R Bellan, A Bellora, J Berenguer Antequera, C Biino, A Cappati, N Cartiglia, S Cometti, M Costa, R Covarelli, N Demaria, B Kiani, F Legger, C Mariotti, S Maselli, E Migliore, V Monaco, E Monteil, M Monteno, M M Obertino, G Ortona, L Pacher, N Pastrone, M Pelliccioni, G L Pinna Angioni, M Ruspa, R Salvatico, F Siviero, V Sola, A Solano, D Soldi, A Staiano, M Tornago, D Trocino, S Belforte, V Candelise, M Casarsa, F Cossutti, A Da Rold, G Della Ricca, F Vazzoler, S Dogra, C Huh, B Kim, D H Kim, G N Kim, J Lee, S W Lee, C S Moon, Y D Oh, S I Pak, B C Radburn-Smith, S Sekmen, Y C Yang, H Kim, D H Moon, B Francois, T J Kim, J Park, S Cho, S Choi, Y Go, S Ha, B Hong, B Kim, K Lee, K S Lee, J Lim, J Park, S K Park, J Yoo, J Goh, A Gurtu, H S Kim, Y Kim, J Almond, J H Bhyun, J Choi, S Jeon, J Kim, J S Kim, S Ko, H Kwon, H Lee, K Lee, S Lee, K Nam, B H Oh, M Oh, S B Oh, H Seo, U K Yang, I Yoon, D Jeon, J H Kim, B Ko, J S H Lee, I C Park, Y Roh, D Song, I J Watson, H D Yoo, Y Choi, C Hwang, Y Jeong, H Lee, Y Lee, I Yu, Y Maghrbi, V Veckalns, A Juodagalvis, A Rinkevicius, G Tamulaitis, A Vaitkevicius, W A T Wan Abdullah, M N Yusli, Z Zolkapli, J F Benitez, A Castaneda Hernandez, J A Murillo Quijada, L Valencia Palomo, G Ayala, H Castilla-Valdez, E De La Cruz-Burelo, I Heredia-De La Cruz, R Lopez-Fernandez, C A Mondragon Herrera, D A Perez Navarro, A Sánchez Hernández, S Carrillo Moreno, C Oropeza Barrera, M Ramírez García, F Vazquez Valencia, J Eysermans, I Pedraza, H A Salazar Ibarguen, C Uribe Estrada, A Morelos Pineda, J Mijuskovic, N Raicevic, D Krofcheck, S Bheesette, P H Butler, A Ahmad, M I Asghar, A Awais, M I M Awan, H R Hoorani, W A Khan, M A Shah, M Shoaib, M Waqas, V Avati, L Grzanka, M Malawski, H Bialkowska, M Bluj, B Boimska, T Frueboes, M Górski, M Kazana, M Szleper, P Traczyk, P Zalewski, K Bunkowski, K Doroba, A Kalinowski, M Konecki, J Krolikowski, M Walczak, M Araujo, P Bargassa, D Bastos, A Boletti, P Faccioli, M Gallinaro, J Hollar, N Leonardo, T Niknejad, J Seixas, K Shchelina, O Toldaiev, J Varela, P Adzic, M Dordevic, P Milenovic, J Milosevic, M Aguilar-Benitez, J Alcaraz Maestre, A Álvarez Fernández, I Bachiller, M Barrio Luna, C F Bedoya, C A Carrillo Montoya, M Cepeda, M Cerrada, N Colino, B De La Cruz, A Delgado Peris, J P Fernández Ramos, J Flix, M C Fouz, O Gonzalez Lopez, S Goy Lopez, J M Hernandez, M I Josa, J León Holgado, D Moran, Á Navarro Tobar, A Pérez-Calero Yzquierdo, J Puerta Pelayo, I Redondo, L Romero, S Sánchez Navas, M S Soares, L Urda Gómez, C Willmott, C Albajar, J F de Trocóniz, R Reyes-Almanza, B Alvarez Gonzalez, J Cuevas, C Erice, J Fernandez Menendez, S Folgueras, I Gonzalez Caballero, E Palencia Cortezon, C Ramón Álvarez, J Ripoll Sau, V Rodríguez Bouza, S Sanchez Cruz, A Trapote, J A Brochero Cifuentes, I J Cabrillo, A Calderon, B Chazin Quero, J Duarte Campderros, M Fernandez, P J Fernández Manteca, A García Alonso, G Gomez, C Martinez Rivero, P Martinez Ruiz Del Arbol, F Matorras, J Piedra Gomez, C Prieels, F Ricci-Tam, T Rodrigo, A Ruiz-Jimeno, L Scodellaro, I Vila, J M Vizan Garcia, M K Jayananda, B Kailasapathy, D U J Sonnadara, D D C Wickramarathna, W G D Dharmaratna, K Liyanage, N Perera, N Wickramage, T K Aarrestad, D Abbaneo, E Auffray, G Auzinger, J Baechler, P Baillon, A H Ball, D Barney, J Bendavid, N Beni, M Bianco, A Bocci, E Bossini, E Brondolin, T Camporesi, M Capeans Garrido, G Cerminara, L Cristella, D d'Enterria, A Dabrowski, N Daci, A David, A De Roeck, M Deile, R Di Maria, M Dobson, M Dünser, N Dupont, A Elliott-Peisert, N Emriskova, F Fallavollita, D Fasanella, S Fiorendi, A Florent, G Franzoni, J Fulcher, W Funk, S Giani, D Gigi, K Gill, F Glege, L Gouskos, M Guilbaud, M Haranko, J Hegeman, Y Iiyama, V Innocente, T James, P Janot, J Kaspar, J Kieseler, M Komm, N Kratochwil, C Lange, S Laurila, P Lecoq, K Long, C Lourenço, L Malgeri, S Mallios, M Mannelli, F Meijers, S Mersi, E Meschi, F Moortgat, M Mulders, S Orfanelli, L Orsini, F Pantaleo, L Pape, E Perez, M Peruzzi, A Petrilli, G Petrucciani, A Pfeiffer, M Pierini, T Quast, D Rabady, A Racz, M Rieger, M Rovere, H Sakulin, J Salfeld-Nebgen, S Scarfi, C Schäfer, M Selvaggi, A Sharma, P Silva, W Snoeys, P Sphicas, S Summers, V R Tavolaro, D Treille, A Tsirou, G P Van Onsem, A Vartak, M Verzetti, K A Wozniak, W D Zeuner, L Caminada, W Erdmann, R Horisberger, Q Ingram, H C Kaestli, D Kotlinski, T Rohe, M Backhaus, P Berger, A Calandri, N Chernyavskaya, A De Cosa, G Dissertori, M Dittmar, M Donegà, C Dorfer, T Gadek, T A Gómez Espinosa, C Grab, D Hits, W Lustermann, A-M Lyon, R A Manzoni, M T Meinhard, F Micheli, F Nessi-Tedaldi, J Niedziela, F Pauss, V Perovic, G Perrin, S Pigazzini, M G Ratti, M Reichmann, C Reissel, T Reitenspiess, B Ristic, D Ruini, D A Sanz Becerra, M Schönenberger, V Stampf, J Steggemann, R Wallny, D H Zhu, C Amsler, C Botta, D Brzhechko, M F Canelli, R Del Burgo, J K Heikkilä, M Huwiler, A Jofrehei, B Kilminster, S Leontsinis, A Macchiolo, P Meiring, V M Mikuni, U Molinatti, I Neutelings, G Rauco, A Reimers, P Robmann, K Schweiger, Y Takahashi, C Adloff, C M Kuo, W Lin, A Roy, T Sarkar, S S Yu, L Ceard, P Chang, Y Chao, K F Chen, P H Chen, W-S Hou, Y Y Li, R-S Lu, E Paganis, A Psallidas, A Steen, E Yazgan, B Asavapibhop, C Asawatangtrakuldee, N Srimanobhas, F Boran, S Damarseckin, Z S Demiroglu, F Dolek, C Dozen, I Dumanoglu, E Eskut, G Gokbulut, Y Guler, E Gurpinar Guler, I Hos, C Isik, E E Kangal, O Kara, A Kayis Topaksu, U Kiminsu, G Onengut, K Ozdemir, A Polatoz, A E Simsek, B Tali, U G Tok, S Turkcapar, I S Zorbakir, C Zorbilmez, B Isildak, G Karapinar, K Ocalan, M Yalvac, B Akgun, I O Atakisi, E Gülmez, M Kaya, O Kaya, Ö Özçelik, S Tekten, E A Yetkin, A Cakir, K Cankocak, Y Komurcu, S Sen, F Aydogmus Sen, S Cerci, B Kaynak, S Ozkorucuklu, D Sunar Cerci, B Grynyov, L Levchuk, E Bhal, S Bologna, J J Brooke, E Clement, D Cussans, H Flacher, J Goldstein, G P Heath, H F Heath, L Kreczko, B Krikler, S Paramesvaran, T Sakuma, S Seif El Nasr-Storey, V J Smith, N Stylianou, J Taylor, A Titterton, K W Bell, A Belyaev, C Brew, R M Brown, D J A Cockerill, K V Ellis, K Harder, S Harper, J Linacre, K Manolopoulos, D M Newbold, E Olaiya, D Petyt, T Reis, T Schuh, C H Shepherd-Themistocleous, A Thea, I R Tomalin, T Williams, R Bainbridge, P Bloch, S Bonomally, J Borg, S Breeze, O Buchmuller, A Bundock, V Cepaitis, G S Chahal, D Colling, P Dauncey, G Davies, M Della Negra, G Fedi, G Hall, G Iles, J Langford, L Lyons, A-M Magnan, S Malik, A Martelli, V Milosevic, J Nash, V Palladino, M Pesaresi, D M Raymond, A Richards, A Rose, E Scott, C Seez, A Shtipliyski, M Stoye, A Tapper, K Uchida, T Virdee, N Wardle, S N Webb, D Winterbottom, A G Zecchinelli, J E Cole, P R Hobson, A Khan, P Kyberd, C K Mackay, I D Reid, L Teodorescu, S Zahid, S Abdullin, A Brinkerhoff, K Call, B Caraway, J Dittmann, K Hatakeyama, A R Kanuganti, C Madrid, B McMaster, N Pastika, S Sawant, C Smith, J Wilson, R Bartek, A Dominguez, R Uniyal, A M Vargas Hernandez, A Buccilli, O Charaf, S I Cooper, S V Gleyzer, C Henderson, C U Perez, P Rumerio, C West, A Akpinar, A Albert, D Arcaro, C Cosby, Z Demiragli, D Gastler, J Rohlf, K Salyer, D Sperka, D Spitzbart, I Suarez, S Yuan, D Zou, G Benelli, B Burkle, X Coubez, D Cutts, Y T Duh, M Hadley, U Heintz, J M Hogan, K H M Kwok, E Laird, G Landsberg, K T Lau, J Lee, M Narain, S Sagir, R Syarif, E Usai, W Y Wong, D Yu, W Zhang, R Band, C Brainerd, R Breedon, M Calderon De La Barca Sanchez, M Chertok, J Conway, R Conway, P T Cox, R Erbacher, C Flores, G Funk, F Jensen, W Ko, O Kukral, R Lander, M Mulhearn, D Pellett, J Pilot, M Shi, D Taylor, K Tos, M Tripathi, Y Yao, F Zhang, M Bachtis, R Cousins, A Dasgupta, D Hamilton, J Hauser, M Ignatenko, M A Iqbal, T Lam, N Mccoll, W A Nash, S Regnard, D Saltzberg, C Schnaible, B Stone, V Valuev, K Burt, Y Chen, R Clare, J W Gary, G Hanson, G Karapostoli, O R Long, N Manganelli, M Olmedo Negrete, W Si, S Wimpenny, Y Zhang, J G Branson, P Chang, S Cittolin, S Cooperstein, N Deelen, J Duarte, R Gerosa, D Gilbert, V Krutelyov, J Letts, M Masciovecchio, S May, S Padhi, M Pieri, V Sharma, M Tadel, F Würthwein, A Yagil, N Amin, C Campagnari, M Citron, A Dorsett, V Dutta, J Incandela, B Marsh, H Mei, A Ovcharova, H Qu, M Quinnan, J Richman, U Sarica, D Stuart, S Wang, A Bornheim, O Cerri, I Dutta, J M Lawhorn, N Lu, J Mao, H B Newman, J Ngadiuba, T Q Nguyen, J Pata, M Spiropulu, J R Vlimant, C Wang, S Xie, Z Zhang, R Y Zhu, J Alison, M B Andrews, T Ferguson, T Mudholkar, M Paulini, I Vorobiev, J P Cumalat, W T Ford, E MacDonald, R Patel, A Perloff, K Stenson, K A Ulmer, S R Wagner, J Alexander, Y Cheng, J Chu, D J Cranshaw, A Datta, A Frankenthal, K Mcdermott, J Monroy, J R Patterson, D Quach, A Ryd, W Sun, S M Tan, Z Tao, J Thom, P Wittich, M Zientek, M Albrow, M Alyari, G Apollinari, A Apresyan, A Apyan, S Banerjee, L A T Bauerdick, A Beretvas, D Berry, J Berryhill, P C Bhat, K Burkett, J N Butler, A Canepa, G B Cerati, H W K Cheung, F Chlebana, M Cremonesi, V D Elvira, J Freeman, Z Gecse, L Gray, D Green, S Grünendahl, O Gutsche, R M Harris, S Hasegawa, R Heller, T C Herwig, J Hirschauer, B Jayatilaka, S Jindariani, M Johnson, U Joshi, P Klabbers, T Klijnsma, B Klima, M J Kortelainen, S Lammel, D Lincoln, R Lipton, M Liu, T Liu, J Lykken, K Maeshima, D Mason, P McBride, P Merkel, S Mrenna, S Nahn, V O'Dell, V Papadimitriou, K Pedro, C Pena, O Prokofyev, F Ravera, A Reinsvold Hall, L Ristori, B Schneider, E Sexton-Kennedy, N Smith, A Soha, W J Spalding, L Spiegel, J Strait, L Taylor, S Tkaczyk, N V Tran, L Uplegger, E W Vaandering, H A Weber, A Woodard, D Acosta, P Avery, D Bourilkov, L Cadamuro, V Cherepanov, F Errico, R D Field, D Guerrero, B M Joshi, M Kim, J Konigsberg, A Korytov, K H Lo, K Matchev, N Menendez, G Mitselmakher, D Rosenzweig, K Shi, J Sturdy, J Wang, X Zuo, T Adams, A Askew, D Diaz, R Habibullah, S Hagopian, V Hagopian, K F Johnson, R Khurana, T Kolberg, G Martinez, H Prosper, C Schiber, R Yohay, J Zhang, M M Baarmand, S Butalla, T Elkafrawy, M Hohlmann, D Noonan, M Rahmani, M Saunders, F Yumiceva, M R Adams, L Apanasevich, H Becerril Gonzalez, R Cavanaugh, X Chen, S Dittmer, O Evdokimov, C E Gerber, D A Hangal, D J Hofman, C Mills, G Oh, T Roy, M B Tonjes, N Varelas, J Viinikainen, X Wang, Z Wu, Z Ye, M Alhusseini, K Dilsiz, S Durgut, R P Gandrajula, M Haytmyradov, V Khristenko, O K Köseyan, J-P Merlo, A Mestvirishvili, A Moeller, J Nachtman, H Ogul, Y Onel, F Ozok, A Penzo, C Snyder, E Tiras, J Wetzel, O Amram, B Blumenfeld, L Corcodilos, M Eminizer, A V Gritsan, S Kyriacou, P Maksimovic, C Mantilla, J Roskes, M Swartz, T Á Vámi, C Baldenegro Barrera, P Baringer, A Bean, S Boren, J Bowen, A Bylinkin, T Isidori, S Khalil, J King, G Krintiras, A Kropivnitskaya, C Lindsey, N Minafra, M Murray, J Ralston, C Rogan, C Royon, S Sanders, E Schmitz, J D Tapia Takaki, Q Wang, J Williams, G Wilson, S Duric, A Ivanov, K Kaadze, D Kim, Y Maravin, T Mitchell, A Modak, A Mohammadi, F Rebassoo, D Wright, E Adams, A Baden, O Baron, A Belloni, S C Eno, Y Feng, N J Hadley, S Jabeen, G Y Jeng, R G Kellogg, T Koeth, A C Mignerey, S Nabili, M Seidel, A Skuja, S C Tonwar, L Wang, K Wong, D Abercrombie, B Allen, R Bi, S Brandt, W Busza, I A Cali, Y Chen, M D'Alfonso, G Gomez-Ceballos, M Goncharov, P Harris, D Hsu, M Hu, M Klute, D Kovalskyi, J Krupa, Y-J Lee, P D Luckey, B Maier, A C Marini, C Mironov, S Narayanan, X Niu, C Paus, D Rankin, C Roland, G Roland, Z Shi, G S F Stephans, K Sumorok, K Tatar, D Velicanu, J Wang, T W Wang, Z Wang, B Wyslouch, R M Chatterjee, A Evans, P Hansen, J Hiltbrand, Sh Jain, M Krohn, Y Kubota, Z Lesko, J Mans, M Revering, R Rusack, R Saradhy, N Schroeder, N Strobbe, M A Wadud, J G Acosta, S Oliveros, K Bloom, S Chauhan, D R Claes, C Fangmeier, L Finco, F Golf, J R González Fernández, C Joo, I Kravchenko, J E Siado, G R Snow, W Tabb, F Yan, G Agarwal, H Bandyopadhyay, L Hay, I Iashvili, A Kharchilava, C McLean, D Nguyen, J Pekkanen, S Rappoccio, G Alverson, E Barberis, C Freer, Y Haddad, A Hortiangtham, J Li, G Madigan, B Marzocchi, D M Morse, V Nguyen, T Orimoto, A Parker, L Skinnari, A Tishelman-Charny, T Wamorkar, B Wang, A Wisecarver, D Wood, S Bhattacharya, J Bueghly, Z Chen, A Gilbert, T Gunter, K A Hahn, N Odell, M H Schmitt, K Sung, M Velasco, R Bucci, N Dev, R Goldouzian, M Hildreth, K Hurtado Anampa, C Jessop, K Lannon, N Loukas, N Marinelli, I Mcalister, F Meng, K Mohrman, Y Musienko, R Ruchti, P Siddireddy, M Wayne, A Wightman, M Wolf, L Zygala, J Alimena, B Bylsma, B Cardwell, L S Durkin, B Francis, C Hill, A Lefeld, B L Winer, B R Yates, B Bonham, P Das, G Dezoort, P Elmer, B Greenberg, N Haubrich, S Higginbotham, A Kalogeropoulos, G Kopp, S Kwan, D Lange, M T Lucchini, J Luo, D Marlow, K Mei, I Ojalvo, J Olsen, C Palmer, P Piroué, D Stickland, C Tully, S Malik, S Norberg, V E Barnes, R Chawla, S Das, L Gutay, M Jones, A W Jung, G Negro, N Neumeister, C C Peng, S Piperov, A Purohit, J F Schulte, M Stojanovic, N Trevisani, F Wang, A Wildridge, R Xiao, W Xie, J Dolen, N Parashar, A Baty, S Dildick, K M Ecklund, S Freed, F J M Geurts, M Kilpatrick, A Kumar, W Li, B P Padley, R Redjimi, J Roberts, J Rorie, W Shi, A G Stahl Leiton, A Bodek, P de Barbaro, R Demina, J L Dulemba, C Fallon, T Ferbel, M Galanti, A Garcia-Bellido, O Hindrichs, A Khukhunaishvili, E Ranken, R Taus, B Chiarito, J P Chou, A Gandrakota, Y Gershtein, E Halkiadakis, A Hart, M Heindl, E Hughes, S Kaplan, O Karacheban, I Laflotte, A Lath, R Montalvo, K Nash, M Osherson, S Salur, S Schnetzer, S Somalwar, R Stone, S A Thayil, S Thomas, H Wang, H Acharya, A G Delannoy, S Spanier, O Bouhali, M Dalchenko, A Delgado, R Eusebi, J Gilmore, T Huang, T Kamon, H Kim, S Luo, S Malhotra, R Mueller, D Overton, L Perniè, D Rathjens, A Safonov, N Akchurin, J Damgov, V Hegde, S Kunori, K Lamichhane, S W Lee, T Mengke, S Muthumuni, T Peltola, S Undleeb, I Volobouev, Z Wang, A Whitbeck, E Appelt, S Greene, A Gurrola, R Janjam, W Johns, C Maguire, A Melo, H Ni, K Padeken, F Romeo, P Sheldon, S Tuo, J Velkovska, M W Arenton, B Cox, G Cummings, J Hakala, R Hirosky, M Joyce, A Ledovskoy, A Li, C Neu, B Tannenwald, E Wolfe, P E Karchin, N Poudyal, P Thapa, K Black, T Bose, J Buchanan, C Caillol, S Dasu, I De Bruyn, P Everaerts, C Galloni, H He, M Herndon, A Hervé, U Hussain, A Lanaro, A Loeliger, R Loveless, J Madhusudanan Sreekala, A Mallampalli, D Pinna, A Savin, V Shang, V Sharma, W H Smith, D Teague, S Trembath-Reichert, W Vetens, S Afanasiev, V Andreev, Yu Andreev, T Aushev, M Azarkin, A Babaev, A Belyaev, V Blinov, E Boos, V Borchsh, P Bunin, V Chekhovsky, R Chistov, M Danilov, A Demiyanov, A Dermenev, T Dimova, I Dremin, V Epshteyn, A Ershov, M Gavrilenko, G Gavrilov, V Gavrilov, S Gninenko, V Golovtcov, N Golubev, I Golutvin, I Gorbunov, A Iuzhakov, V Ivanchenko, Y Ivanov, V Kachanov, A Kalinin, A Kamenev, L Kardapoltsev, V Karjavine, A Karneyeu, V Kim, M Kirakosyan, M Kirsanov, O Kodolova, D Konstantinov, V Korotkikh, N Krasnikov, E Kuznetsova, A Lanev, A Litomin, O Lukina, N Lychkovskaya, V Makarenko, A Malakhov, V Matveev, V Murzin, A Nikitenko, S Obraztsov, V Okhotnikov, V Oreshkin, A Oskin, I Ovtin, V Palichik, P Parygin, A Pashenkov, V Perelygin, S Petrushanko, G Pivovarov, S Polikarpov, V Popov, G Safronov, M Savina, V Savrin, V Shalaev, S Shmatov, S Shulha, Y Skovpen, I Smirnov, V Smirnov, A Snigirev, D Sosnov, A Spiridonov, A Stepennov, J Suarez Gonzalez, L Sukhikh, V Sulimov, E Tcherniaev, A Terkulov, O Teryaev, D Tlisov, M Toms, A Toropin, L Uvarov, A Uzunian, I Vardanyan, E Vlasov, S Volkov, A Vorobyev, N Voytishin, B S Yuldashev, A Zarubin, I Zhizhin, A Zhokin
The structure of nucleons is multidimensional and depends on the transverse momenta, spatial geometry, and polarization of the constituent partons. Such a structure can be studied using high-energy photons produced in ultraperipheral heavy-ion collisions. The first measurement of the azimuthal angular correlations of exclusively produced events with two jets in photon-lead interactions at large momentum transfer is presented, a process that is considered to be sensitive to the underlying nuclear gluon polarization...
August 4, 2023: Physical Review Letters
https://read.qxmd.com/read/37583267/mortality-risk-reduction-with-budesonide-glycopyrrolate-formoterol-fumarate-versus-fluticasone-furoate-umeclidinium-vilanterol-in-copd-a-matching-adjusted-indirect-comparison-based-on-ethos-and-impact
#27
JOURNAL ARTICLE
Daiana Stolz, Erik Hermansson, Mario Ouwens, Barinder Singh, Akanksha Sharma, Dan Jackson, Patrick Darken, Jonathan Marshall, Karin Bowen, Hana Müllerová, Bernardino Alcázar Navarrete, Richard Russell, MeiLan K Han, Deniz Tansey-Dwyer
OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. While two approved fixed-dose inhaled corticosteroid/long-acting muscarinic antagonist (LAMA)/long-acting β2 -agonist (LABA) triple therapies reduce all-cause mortality (ACM) versus dual LAMA/LABA therapy in patients with COPD, head-to-head studies have not compared the effects of these therapies on ACM. We compared ACM in adults with moderate-to-very severe COPD receiving budesonide/glycopyrrolate/formoterol fumarate (BGF) in ETHOS versus fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) in IMPACT using a matching-adjusted indirect comparison (MAIC)...
August 15, 2023: Current Medical Research and Opinion
https://read.qxmd.com/read/37549274/near-term-tropical-cyclone-risk-and-coupled-earth-system-model-biases
#28
JOURNAL ARTICLE
Adam H Sobel, Chia-Ying Lee, Steven G Bowen, Suzana J Camargo, Mark A Cane, Amy Clement, Boniface Fosu, Megan Hart, Kevin A Reed, Richard Seager, Michael K Tippett
Most current climate models predict that the equatorial Pacific will evolve under greenhouse gas-induced warming to a more El Niño-like state over the next several decades, with a reduced zonal sea surface temperature gradient and weakened atmospheric Walker circulation. Yet, observations over the last 50 y show the opposite trend, toward a more La Niña-like state. Recent research provides evidence that the discrepancy cannot be dismissed as due to internal variability but rather that the models are incorrectly simulating the equatorial Pacific response to greenhouse gas warming...
August 15, 2023: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/37493935/walking-status-and-spinopelvic-parameters-in-young-children-with-achondroplasia-10-year-follow-up
#29
JOURNAL ARTICLE
Luiz Carlos Almeida da Silva, Ali Asma, Armagan Can Ulusaloglu, Megan Margetts, Colleen P Ditro, Kenneth J Rogers, J Richard Bowen, William G Mackenzie, W G Stuart Mackenzie
PURPOSE: Thoracolumbar kyphosis (TLK) is common in children with achondroplasia and resolves in 90% by 10 years of age. Our purpose was to describe the natural progression of TLK in a cohort of pre-walking children with achondroplasia. METHODS: A single-center, retrospective review identified 62 children (32 male, 30 female) with achondroplasia. Clinical information and sagittal spinopelvic parameters were collected. The children were divided into positive pelvic tilt (PT) and negative PT...
July 26, 2023: Spine Deformity
https://read.qxmd.com/read/37461624/multi-ancestry-genome-wide-meta-analysis-of-56-241-individuals-identifies-lrrc4c-lhx5-as1-and-nominates-ancestry-specific-loci-ptprk-grb14-and-kiaa0825-as-novel-risk-loci-for-alzheimer-s-disease-the-alzheimer-s-disease-genetics-consortium
#30
Farid Rajabli, Penelope Benchek, Giuseppe Tosto, Nicholas Kushch, Jin Sha, Katrina Bazemore, Congcong Zhu, Wan-Ping Lee, Jacob Haut, Kara L Hamilton-Nelson, Nicholas R Wheeler, Yi Zhao, John J Farrell, Michelle A Grunin, Yuk Yee Leung, Pavel P Kuksa, Donghe Li, Eder Lucio da Fonseca, Jesse B Mez, Ellen L Palmer, Jagan Pillai, Richard M Sherva, Yeunjoo E Song, Xiaoling Zhang, Taha Iqbal, Omkar Pathak, Otto Valladares, Amanda B Kuzma, Erin Abner, Perrie M Adams, Alyssa Aguirre, Marilyn S Albert, Roger L Albin, Mariet Allen, Lisa Alvarez, Liana G Apostolova, Steven E Arnold, Sanjay Asthana, Craig S Atwood, Gayle Ayres, Clinton T Baldwin, Robert C Barber, Lisa L Barnes, Sandra Barral, Thomas G Beach, James T Becker, Gary W Beecham, Duane Beekly, Bruno A Benitez, David Bennett, John Bertelson, Thomas D Bird, Deborah Blacker, Bradley F Boeve, James D Bowen, Adam Boxer, James Brewer, James R Burke, Jeffrey M Burns, Joseph D Buxbaum, Nigel J Cairns, Laura B Cantwell, Chuanhai Cao, Christopher S Carlson, Cynthia M Carlsson, Regina M Carney, Minerva M Carrasquillo, Scott Chasse, Marie-Francoise Chesselet, Nathaniel A Chin, Helena C Chui, Jaeyoon Chung, Suzanne Craft, Paul K Crane, David H Cribbs, Elizabeth A Crocco, Carlos Cruchaga, Michael L Cuccaro, Munro Cullum, Eveleen Darby, Barbara Davis, Philip L De Jager, Charles DeCarli, John DeToledo, Malcolm Dick, Dennis W Dickson, Beth A Dombroski, Rachelle S Doody, Ranjan Duara, NIlüfer Ertekin-Taner, Denis A Evans, Kelley M Faber, Thomas J Fairchild, Kenneth B Fallon, David W Fardo, Martin R Farlow, Victoria Fernandez-Hernandez, Steven Ferris, Tatiana M Foroud, Matthew P Frosch, Brian Fulton-Howard, Douglas R Galasko, Adriana Gamboa, Marla Gearing, Daniel H Geschwind, Bernardino Ghetti, John R Gilbert, Alison M Goate, Thomas J Grabowski, Neill R Graff-Radford, Robert C Green, John H Growdon, Hakon Hakonarson, James Hall, Ronald L Hamilton, Oscar Harari, John Hardy, Lindy E Harrell, Elizabeth Head, Victor W Henderson, Michelle Hernandez, Timothy Hohman, Lawrence S Honig, Ryan M Huebinger, Matthew J Huentelman, Christine M Hulette, Bradley T Hyman, Linda S Hynan, Laura Ibanez, Gail P Jarvik, Suman Jayadev, Lee-Way Jin, Kim Johnson, Leigh Johnson, M Ilyas Kamboh, Anna M Karydas, Mindy J Katz, John S Kauwe, Jeffrey A Kaye, C Dirk Keene, Aisha Khaleeq, Ronald Kim, Janice Knebl, Neil W Kowall, Joel H Kramer, Walter A Kukull, Frank M LaFerla, James J Lah, Eric B Larson, Alan Lerner, James B Leverenz, Allan I Levey, Andrew P Lieberman, Richard B Lipton, Mark Logue, Oscar L Lopez, Kathryn L Lunetta, Constantine G Lyketsos, Douglas Mains, Flanagan E Margaret, Daniel C Marson, Eden R R Martin, Frank Martiniuk, Deborah C Mash, Eliezer Masliah, Paul Massman, Arjun Masurkar, Wayne C McCormick, Susan M McCurry, Andrew N McDavid, Stefan McDonough, Ann C McKee, Marsel Mesulam, Bruce L Miller, Carol A Miller, Joshua W Miller, Thomas J Montine, Edwin S Monuki, John C Morris, Shubhabrata Mukherjee, Amanda J Myers, Trung Nguyen, Sid O'Bryant, John M Olichney, Marcia Ory, Raymond Palmer, Joseph E Parisi, Henry L Paulson, Valory Pavlik, David Paydarfar, Victoria Perez, Elaine Peskind, Ronald C Petersen, Aimee Pierce, Marsha Polk, Wayne W Poon, Huntington Potter, Liming Qu, Mary Quiceno, Joseph F Quinn, Ashok Raj, Murray Raskind, Eric M Reiman, Barry Reisberg, Joan S Reisch, John M Ringman, Erik D Roberson, Monica Rodriguear, Ekaterina Rogaeva, Howard J Rosen, Roger N Rosenberg, Donald R Royall, Mark A Sager, Mary Sano, Andrew J Saykin, Julie A Schneider, Lon S Schneider, William W Seeley, Susan H Slifer, Scott Small, Amanda G Smith, Janet P Smith, Joshua A Sonnen, Salvatore Spina, Peter St George-Hyslop, Robert A Stern, Alan B Stevens, Stephen M Strittmatter, David Sultzer, Russell H Swerdlow, Rudolph E Tanzi, Jeffrey L Tilson, John Q Trojanowski, Juan C Troncoso, Debby W Tsuang, Vivianna M Van Deerlin, Linda J van Eldik, Jeffery M Vance, Badri N Vardarajan, Robert Vassar, Harry V Vinters, Jean-Paul Vonsattel, Sandra Weintraub, Kathleen A Welsh-Bohmer, Patrice L Whitehead, Ellen M Wijsman, Kirk C Wilhelmsen, Benjamin Williams, Jennifer Williamson, Henrik Wilms, Thomas S Wingo, Thomas Wisniewski, Randall L Woltjer, Martin Woon, Clinton B Wright, Chuang-Kuo Wu, Steven G Younkin, Chang-En Yu, Lei Yu, Xiongwei Zhu, Brian W Kunkle, William S Bush, Li-San Wang, Lindsay A Farrer, Jonathan L Haines, Richard Mayeux, Margaret A Pericak-Vance, Gerard D Schellenberg, Gyungah R Jun, Christiane Reitz, Adam C Naj
Limited ancestral diversity has impaired our ability to detect risk variants more prevalent in non-European ancestry groups in genome-wide association studies (GWAS). We constructed and analyzed a multi-ancestry GWAS dataset in the Alzheimer's Disease (AD) Genetics Consortium (ADGC) to test for novel shared and ancestry-specific AD susceptibility loci and evaluate underlying genetic architecture in 37,382 non-Hispanic White (NHW), 6,728 African American, 8,899 Hispanic (HIS), and 3,232 East Asian individuals, performing within-ancestry fixed-effects meta-analysis followed by a cross-ancestry random-effects meta-analysis...
July 8, 2023: medRxiv
https://read.qxmd.com/read/37408391/hammett-correlation-in-competition-experiments-in-dissociation-of-ionised-substituted-benzophenones-and-dibenzylideneacetones
#31
JOURNAL ARTICLE
Nathan W Fenwick, Richard Telford, William H C Martin, Richard D Bowen
A convenient method of applying competition experiments to devise a Hammett correlation in the dissociation by α-cleavage of 17 ionised 3- and 4-substituted benzophenones, YC6 H4 COC6 H5 [Y=F, Cl, Br, CH3 , CH3 O, NH2 , CF3 , OH, NO2 , CN and N(CH3 )2 ] is reported and discussed. The results given by this approach, which rely on the relative abundance of [M-C6 H5 ]+ and [M-C6 H4 Y]+ ions in the electron ionisation spectra of the substituted benzophenones, are compared with those obtained by previous methods...
July 5, 2023: European Journal of Mass Spectrometry
https://read.qxmd.com/read/37376452/intranasal-single-replication-influenza-vector-induces-cross-reactive-serum-and-mucosal-antibodies-against-sars-cov-2-variants
#32
JOURNAL ARTICLE
Michael J Moser, Lindsay Hill-Batorski, Richard A Bowen, Sarah M Matejka, David Marshall, Yoshihiro Kawaoka, Gabriele Neumann, Pamuk Bilsel
Current SARS-CoV-2 vaccines provide protection for COVID-19-associated hospitalization and death, but remain inefficient at inhibiting initial infection and transmission. Despite updated booster formulations, breakthrough infections and reinfections from emerging SARS-CoV-2 variants are common. Intranasal vaccination to elicit mucosal immunity at the site of infection can improve the performance of respiratory virus vaccines. We developed SARS-CoV-2 M2SR, a dual SARS-CoV-2 and influenza vaccine candidate, employing our live intranasal M2-deficient single replication (M2SR) influenza vector expressing the receptor binding domain (RBD) of the SARS-CoV-2 Spike protein of the prototype strain, first reported in January 2020...
June 5, 2023: Vaccines
https://read.qxmd.com/read/37298743/broccoli-kale-and-radish-sprouts-key-phytochemical-constituents-and-dpph-free-radical-scavenging-activity
#33
JOURNAL ARTICLE
Camille Bowen-Forbes, Edward Armstrong, Audric Moses, Richard Fahlman, Helia Koosha, Jerome Y Yager
Our research group previously found that broccoli sprouts possess neuroprotective effects during pregnancy. The active compound has been identified as sulforaphane (SFA), obtained from glucosinolate and glucoraphanin, which are also present in other crucifers, including kale. Sulforaphene (SFE), obtained from glucoraphenin in radish, also has numerous biological benefits, some of which supersede those of sulforaphane. It is likely that other components, such as phenolics, contribute to the biological activity of cruciferous vegetables...
May 23, 2023: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/37249207/nanophase-photocatalysis-loading-storing-and-release-of-h-2-o-2-using-graphitic-carbon-nitride
#34
JOURNAL ARTICLE
Akalya Karunakaran, Katie J Francis, Chris R Bowen, Richard J Ball, Yuanzhu Zhao, Lina Wang, Neil B McKeown, Mariolino Carta, Philip J Fletcher, Remi Castaing, Mark A Isaacs, Laurence J Hardwick, Gema Cabello, Igor V Sazanovich, Frank Marken
A blue light mediated photochemical process using solid graphitic carbon nitride (g-C3 N4 ) in ambient air/isopropanol vapour is suggested to be linked to "nanophase" water inclusions and is shown to produce approx. 50 μmol H2 O2 per gram of g-C3 N4 , which can be stored in the solid g-C3 N4 for later release for applications, for example, in disinfection or anti-bacterial surfaces.
May 30, 2023: Chemical Communications: Chem Comm
https://read.qxmd.com/read/37242308/disease-progression-and-serological-assay-performance-in-heritage-breed-pigs-following-brucella-suis-experimental-challenge-as-a-model-for-naturally-infected-feral-swine
#35
JOURNAL ARTICLE
Vienna R Brown, Ryan S Miller, Courtney F Bowden, Timothy J Smyser, Nicholas A Ledesma, Airn Hartwig, Paul Gordy, Aaron M Anderson, Stephanie M Porter, Kate Alexander, Zane Gouker, Thomas Gidlewski, Richard A Bowen, Angela M Bosco-Lauth
Invasive feral swine ( Sus scrofa ) are one of the most important wildlife species for disease surveillance in the United States, serving as a reservoir for various diseases of concern for the health of humans and domestic animals. Brucella suis , the causative agent of swine brucellosis, is one such pathogen carried and transmitted by feral swine. Serology assays are the preferred field diagnostic for B. suis infection, as whole blood can be readily collected and antibodies are highly stable. However, serological assays frequently have lower sensitivity and specificity, and few studies have validated serological assays for B...
April 24, 2023: Pathogens
https://read.qxmd.com/read/37185078/a-sonography-based-decision-model-for-use-in-treatment-of-developmental-dysplasia-of-the-hip
#36
JOURNAL ARTICLE
Brian Po-Jung Chen, H Theodore Harcke, Kenneth J Rogers, J Richard Bowen
The objective of this study was to delineate a model for management of developmental dysplasia of the hip (DDH) treatment that incorporates hip ultrasound with objective/predicative parameters at key decision-making times. Hip sonograms of 74 infants (59 females, 15 males; 141 hips) with DDH were retrospectively reviewed. Hip sonographic score (HSS; ranges 0-10) was developed to reflect hip status based on sonographic position, stability, and morphology. Analysis on different management groups (i.e., no treatment, successful treatment, and failed treatment) showed that the trend of HSS is helpful in predicting course of the disease and determining effectiveness of treatment...
2023: Journal of Surgical Orthopaedic Advances
https://read.qxmd.com/read/37162533/advanced-statistics-identification-of-participant-and-treatment-predictors-associated-with-severe-adverse-effects-induced-by-fluoropyrimidine-based-chemotherapy
#37
JOURNAL ARTICLE
Samantha K Korver, Joanne M Bowen, Rachel J Gibson, Imogen A Ball, Kate R Secombe, Taylor J Wain, Richard M Logan, Jonathan Tuke, Kelly R Mead, Alison M Richards, Christos S Karapetis, Dorothy M Keefe, Janet K Coller
PURPOSE: Adverse effects following fluoropyrimidine-based chemotherapy regimens are common. However, there are no current accepted diagnostic markers for prediction prior to treatment, and the underlying mechanisms remain unclear. This study aimed to determine genetic and non-genetic predictors of adverse effects. METHODS: Genomic DNA was analyzed for 25 single nucleotide polymorphisms (SNPs). Demographics, comorbidities, cancer and fluoropyrimidine-based chemotherapy regimen types, and adverse effect data were obtained from clinical records for 155 Australian White participants...
May 10, 2023: Cancer Chemotherapy and Pharmacology
https://read.qxmd.com/read/37148585/broad-immunity-to-sars-cov-2-variants-of-concern-mediated-by-a-sars-cov-2-receptor-binding-domain-protein-vaccine
#38
JOURNAL ARTICLE
Georgia Deliyannis, Nicholas A Gherardin, Chinn Yi Wong, Samantha L Grimley, James P Cooney, Samuel J Redmond, Paula Ellenberg, Kathryn C Davidson, Francesca L Mordant, Tim Smith, Marianne Gillard, Ester Lopez, Julie McAuley, Chee Wah Tan, Jing J Wang, Weiguang Zeng, Mason Littlejohn, Runhong Zhou, Jasper Fuk-Woo Chan, Zhi-Wei Chen, Airn E Hartwig, Richard Bowen, Jason M Mackenzie, Elizabeth Vincan, Joseph Torresi, Katherine Kedzierska, Colin W Pouton, Tom P Gordon, Lin-Fa Wang, Stephen J Kent, Adam K Wheatley, Sharon R Lewin, Kanta Subbarao, Amy W Chung, Marc Pellegrini, Trent Munro, Terry Nolan, Steven Rockman, David C Jackson, Damian F J Purcell, Dale I Godfrey
BACKGROUND: The SARS-CoV-2 global pandemic has fuelled the generation of vaccines at an unprecedented pace and scale. However, many challenges remain, including: the emergence of vaccine-resistant mutant viruses, vaccine stability during storage and transport, waning vaccine-induced immunity, and concerns about infrequent adverse events associated with existing vaccines. METHODS: We report on a protein subunit vaccine comprising the receptor-binding domain (RBD) of the ancestral SARS-CoV-2 spike protein, dimerised with an immunoglobulin IgG1 Fc domain...
May 4, 2023: EBioMedicine
https://read.qxmd.com/read/37111508/feral-swine-as-indirect-indicators-of-environmental-anthrax-contamination-and-potential-mechanical-vectors-of-infectious-spores
#39
JOURNAL ARTICLE
Rachel M Maison, Maggie R Priore, Vienna R Brown, Michael J Bodenchuk, Bradley R Borlee, Richard A Bowen, Angela M Bosco-Lauth
Anthrax is a disease that affects livestock, wildlife, and humans worldwide; however, its relative impacts on these populations remain underappreciated. Feral swine ( Sus scrofa ) are relatively resistant to developing anthrax, and past serosurveys have alluded to their utility as sentinels, yet empirical data to support this are lacking. Moreover, whether feral swine may assist in the dissemination of infectious spores is unknown. To address these knowledge gaps, we intranasally inoculated 15 feral swine with varying quantities of Bacillus anthracis Sterne 34F2 spores and measured the seroconversion and bacterial shedding over time...
April 20, 2023: Pathogens
https://read.qxmd.com/read/37074435/histo-blood-group-antigen-null-phenotypes-associated-with-a-decreased-risk-of-clinical-rotavirus-vaccine-failure-among-children-2-years-of-age-participating-in-the-vaccine-impact-on-diarrhea-in-africa-vida-study-in-kenya-mali-and-the-gambia
#40
JOURNAL ARTICLE
Lauren M Schwartz, Jennifer Oshinsky, Mardi Reymann, Mathew D Esona, Michael D Bowen, M Jahangir Hossain, Syed M A Zaman, Joquina Chiquita M Jones, Martin Antonio, Henry Badji, Golam Sarwar, Samba O Sow, Doh Sanogo, Adama Mamby Keita, Boubou Tamboura, Awa Traoré, Uma Onwuchekwa, Richard Omore, Jennifer R Verani, Alex O Awuor, John B Ochieng, Jane Juma, Billy Ogwel, Umesh D Parashar, Jacqueline E Tate, Irene N Kasumba, Sharon M Tennant, Kathleen M Neuzil, Ali Rowhani-Rahbar, M Elizabeth Halloran, Robert L Atmar, Marcela F Pasetti, Karen L Kotloff
BACKGROUND: Previously studied risk factors for rotavirus vaccine failure have not fully explained reduced rotavirus vaccine effectiveness in low-income settings. We assessed the relationship between histo-blood group antigen (HBGA) phenotypes and clinical rotavirus vaccine failure among children <2 years of age participating in the Vaccine Impact on Diarrhea in Africa Study in 3 sub-Saharan African countries. METHODS: Saliva was collected and tested for HBGA phenotype in children who received rotavirus vaccine...
April 19, 2023: Clinical Infectious Diseases
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