Anetta Undas, Piotr Podolec, Krystyna Zawilska, Monika Pieculewicz, Ireneusz Jedliński, Ewa Stepień, Ewa Konarska-Kuszewska, Przemysław Weglarz, Malłgorzata Duszyńska, Ewelina Hanschke, Tadeusz Przewlocki, Wiesława Tracz
BACKGROUND AND PURPOSE: We tested the hypothesis that fibrin structure/function is unfavorably altered in patients with cryptogenic ischemic stroke. METHODS: Ex vivo plasma fibrin clot permeability, turbidimetry, and efficiency of fibrinolysis were determined in 89 patients with patent foramen ovale (PFO) and a history of first-ever stroke, 58 patients with first-ever stroke and no PFO, and 120 healthy controls. RESULTS: Stroke patients, evaluated 3 to 19 months after the event, and controls did not differ with regard to age, sex, smoking, and fibrinogen...
April 2009: Stroke; a Journal of Cerebral Circulation