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Cannabinod depression

Juan Pablo Prestifilippo, Javier Fernández-Solari, Vanina Medina, Valeria Rettori, Juan Carlos Elverdin
AIM: The aim of the present study was to determine whether the endocannabinoid system could be involved in the ethanol-induced inhibition of salivation in adult male Wistar rats. METHODS: Salivary secretion induced by different concentrations of methacholine, a cholinergic agonist, and the endocannabinoid arachidonoyl ethanolamide (anandamide, AEA) production in the submandibular gland (SMG) were determined in rats after ethanol (3 g/kg) administration by gastric gavage...
September 2009: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
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