Elyas Mohammadi, Samira Dashti, Neda Shafizade, Han Jin, Cheng Zhang, Simon Lam, Mojtaba Tahmoorespur, Adil Mardinoglu, Mohammad Hadi Sekhavati
Immunomodulatory peptides, while exhibiting potential antimicrobial, antifungal, and/or antiviral properties, can play a role in stimulating or suppressing the immune system, especially in pathological conditions like breast cancer (BC). Thus, deregulation of these peptides may serve as an immunotherapeutic strategy to enhance the immune response. In this meta-analysis, we utilized single-cell RNA sequencing data and known therapeutic peptides to investigate the deregulation of these peptides in malignant versus normal human breast epithelial cells...
April 8, 2024: NPJ Systems Biology and Applications