Andrew J Palmer, Paul Lochhead, Georgina L Hold, Charles S Rabkin, Wong-Ho Chow, Jolanta Lissowska, Thomas L Vaughan, Susan Berry, Marilie Gammon, Harvey Risch, Emad M El-Omar
Recently, two large genome-wide association studies, conducted in Chinese populations, have reported associations between upper gastrointestinal cancer and the rs2274223, rs13042395 and rs4072037 polymorphisms in PLCE1, C20orf54 and MUC1, respectively. We aimed to determine whether similar associations existed for Caucasian populations. We genotyped two population-based, case-control studies of upper gastrointestinal cancer; the first study included 290 gastric cancer (GC) cases and 376 controls and the second study included 306 GC cases, 107 oesophageal adenocarcinoma cancer cases, 52 oesphageal squamous cell cancer cases and 211 controls...
November 2012: European Journal of Cancer Prevention