keyword
https://read.qxmd.com/read/38528773/exploring-the-demographic-and-professional-characteristics-of-physicians-and-nurse-practitioners-associated-with-providing-medication-assisted-treatment-a-retrospective-observational-study
#21
JOURNAL ARTICLE
Hannah L Maxey, Sierra X Vaughn, Analise Dickinson, Robin Newhouse
Integration of medication-assisted treatment (MAT) for opioid use disorder in primary care settings is an emerging health care delivery model that supports increased access to specialized care but requires primary care provider engagement. Examining the characteristics of providers who provide this service is key to informing targeted recruitment. Using administrative and supplemental data collected during license renewal, this study aimed to identify the characteristics of primary care physicians and nurse practitioners (NPs) associated with greater odds of providing MAT in their practice...
2024: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://read.qxmd.com/read/38528562/the-value-of-machine-learning-technology-and-artificial-intelligence-to-enhance-patient-safety-in-spine-surgery-a-review
#22
REVIEW
Fatemeh Arjmandnia, Ehsan Alimohammadi
Machine learning algorithms have the potential to significantly improve patient safety in spine surgeries by providing healthcare professionals with valuable insights and predictive analytics. These algorithms can analyze preoperative data, such as patient demographics, medical history, and imaging studies, to identify potential risk factors and predict postoperative complications. By leveraging machine learning, surgeons can make more informed decisions, personalize treatment plans, and optimize surgical techniques to minimize risks and enhance patient outcomes...
March 25, 2024: Patient Safety in Surgery
https://read.qxmd.com/read/38527317/implementation-of-an-evidence-based-content-validated-standardized-support-surface-algorithm-tool-in-home-health-care-a-quality-improvement-project
#23
JOURNAL ARTICLE
Monica Timko-Progar, Jerri Drain, Kimberly Stovall-Patton
PURPOSE: The purpose of this quality improvement project was to provide a standardized, repeatable, and easy-to-use process for selecting a support surface for prevention or treatment of pressure injuries (PIs). PARTICIPANTS AND SETTING: The Wound, Ostomy, and Continence Nurses Society Support Surface Algorithm was chosen to guide clinicians in selection of an appropriate support surface. These clinicians provide services to approximately 465,000 patients across the nation annually...
March 2024: Journal of Wound, Ostomy, and Continence Nursing
https://read.qxmd.com/read/38527268/impacts-of-ground-ultra-low-volume-adulticide-applications-on-culex-pipiens-and-culex-restuans-diptera-culicidae-abundance-age-structure-and-west-nile-virus-infection-in-cook-county-illinois
#24
JOURNAL ARTICLE
Kristina Lopez, Katie Susong, Patrick Irwin, Susan Paskewitz, Lyric Bartholomay
Since the introduction of West Nile virus (WNV) to the United States over 20 years ago, thousands of cases of human disease and death have been reported. Yearly seasonal outbreaks continue to persist, and the city and suburbs of Chicago, Illinois, is considered a "hot spot" for WNV activity. To interrupt WNV transmission, ground ultra-low volume (ULV) adulticide applications are regularly used to reduce Culex pipiens L. and Culex restuans Theobold (Diptera: Culicidae) abundance and infection. The real-world effectiveness of adulticide applications has not been comprehensively assessed, and prior studies, including our own investigation, have yielded inconclusive or conflicting results...
March 25, 2024: Journal of Medical Entomology
https://read.qxmd.com/read/38526813/-secondary-fracture-prevention-update-osteoporosis-guidelines-2023-of-the-umbrella-organization-osteology
#25
REVIEW
Ulla Stumpf, Ralf Schmidmaier
The S3 guidelines on the prophylaxis, diagnostics and treatment of osteoporosis 2023 were completely revised and updated between 2021 and 2023 in accordance with the Association of the Scientific Medical Societies of Germany (AWMF) regulations. The guideline committee consisted of delegates from the 20 specialist societies of the Umbrella Organization Osteology (Dachverband Osteologie, DVO) as well as delegates from the German Society of General Medicine and Family Medicine (DEGAM), the German Society for Nephrology (DGfN) and the Federal Self-help Association for Osteoporosis (BfO)...
April 2024: Unfallchirurgie (Heidelb)
https://read.qxmd.com/read/38526711/advancing-emergency-medical-services-ems-response-capability-for-behavioral-health-emergencies-los-angeles-county-s-performance-improvement-initiative
#26
JOURNAL ARTICLE
Erick H Cheung, Denise A Whitfield, Adam Kipust, Richard Tadeo, Marianne Gausche-Hill
Introduction: Behavioral health emergencies (BHEs) are a common patient encounter for emergency medical services (EMS) clinicians and other first responders, in particular law enforcement (LE) officers. It is critical for EMS clinicians to have management strategies for BHEs, yet relatively little information exists on best practices. In 2016, the Los Angeles County EMS Agency's Commission initiated a comprehensive evaluation of the 9-1-1 response for BHEs and developed a plan for improving the quality of care and safety for patients and first responders...
March 25, 2024: Prehospital Emergency Care
https://read.qxmd.com/read/38526672/degradable-silk-fibroin-based-piezoresistive-sensor-for-wearable-biomonitoring
#27
JOURNAL ARTICLE
Chunlin Pang, Fei Li, Xiaorao Hu, Keyu Meng, Hong Pan, Yong Xiang
Degradable wearable electronics are attracting increasing attention to weaken or eliminate the negative effect of waste e-wastes and promote the development of medical implants without secondary post-treatment. Although various degradable materials have been explored for wearable electronics, the development of degradable wearable electronics with integrated characteristics of highly sensing performances and low-cost manufacture remains challenging. Herein, we developed a facile, low-cost, and environmentally friendly approach to fabricate a biocompatible and degradable silk fibroin based wearable electronics (SFWE) for on-body monitoring...
March 25, 2024: Discov Nano
https://read.qxmd.com/read/38526631/disulfidptosis-features-and-prognosis-in-head-and-neck-squamous-cell-carcinoma-patients-unveiling-and-validating-the-prognostic-signature-across-cohorts
#28
JOURNAL ARTICLE
Hao Xue, Qianyu Sun, Heqing Zhang, Hanxiao Huang, Haowei Xue
BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is a significant health concern with a variable global incidence and is linked to regional lifestyle factors and HPV infections. Despite treatment advances, patient prognosis remains variable, necessitating an understanding of its molecular mechanisms and the identification of reliable prognostic biomarkers. METHODS: We analyzed 959 HNSCC samples and employed batch correction to obtain consistent transcriptomic data across cohorts...
March 25, 2024: Journal of Cancer Research and Clinical Oncology
https://read.qxmd.com/read/38526609/nephroblastoma-specific-dysregulated-gene-snhg15-with-prognostic-significance-scrna-seq-with-bulk-rna-seq-data-and-experimental-validation
#29
JOURNAL ARTICLE
Mengmeng Chang, Ding Li, Li Su, Chen Ding, Zhiyi Lu, Hongjie Gao, Fengyin Sun
Wilms tumor (WT) is the most common malignancy of the genitourinary system in children. Currently, the Integration of single-cell RNA sequencing (scRNA-Seq) and Bulk RNA sequencing (RNA-Seq) analysis of heterogeneity between different cell types in pediatric WT tissues could more accurately find prognostic markers, but this is lacking. RNA-Seq and clinical data related to WT were downloaded from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) database. Small nucleolar RNA host gene 15 (SNHG15) was identified as a risk signature from the TARGET dataset by using weighted gene co-expression network analysis, differentially expressed analysis and univariate Cox analysis...
March 25, 2024: Discover. Oncology
https://read.qxmd.com/read/38525882/artificial-intelligence-to-advance-acute-and-intensive-care-medicine
#30
JOURNAL ARTICLE
Laurens A Biesheuvel, Dave A Dongelmans, Paul W G Elbers
PURPOSE OF REVIEW: This review explores recent key advancements in artificial intelligence for acute and intensive care medicine. As artificial intelligence rapidly evolves, this review aims to elucidate its current applications, future possibilities, and the vital challenges that are associated with its integration into emergency medical dispatch, triage, medical consultation and ICUs. RECENT FINDINGS: The integration of artificial intelligence in emergency medical dispatch (EMD) facilitates swift and accurate assessment...
March 14, 2024: Current Opinion in Critical Care
https://read.qxmd.com/read/38525731/pharmacy-students-perceived-ability-to-implement-the-pharmacist-s-patient-care-process-before-and-after-a-redesigned-case-study-series-in-the-united-states
#31
JOURNAL ARTICLE
Amy Henneman, Samantha Axtell
Since the incorporation of the Pharmacist's Patient Care Process (PPCP) into the American Association of Colleges of Pharmacy standards, the process has been integrated in a variety of ways across curriculums. A two-semester case-based course was redesigned as a four-semester case-based course formally integrating the PPCP. Pharmacy students completing the original, two-semester course series and those completing the first two semesters of the redesigned course were given a voluntary survey to assess their perceived ability to integrate the PPCP into practice after the completion of each course...
March 19, 2024: Pharmacy (Basel, Switzerland)
https://read.qxmd.com/read/38525641/evaluation-of-the-impact-of-pepfar-transition-on-retention-in-care-in-south-africa-s-western-cape-province
#32
JOURNAL ARTICLE
J Chiliza, R Laing, F G Feeley, A T Brennan
BACKGROUND: Research on the impact of the US President's Emergency Plan for AIDS Relief (PEPFAR) transition in South Africa (SA) in 2012 found varying results in retention in care (RIC) of people living with HIV (PLWH). OBJECTIVES: To investigate the factors that impacted RIC during the PEPFAR transition in Western Cape Province, SA, in 2012. METHODS: We used aggregate data from 61 facilities supported by four non-governmental organisations from 2007 to 2015...
December 31, 2023: South African Medical Journal
https://read.qxmd.com/read/38525626/implementing-e-motive-for-detection-and-treatment-of-postpartum-haemorrhage-in-south-africa
#33
JOURNAL ARTICLE
M Singata-Madliki, S Fawcus, N Moran, E Arends, E Muller, S Mandondo, G J Hofmeyr
Postpartum haemorrhage is the leading cause of preventable maternal mortality in South Africa. In a significant breakthrough in the management of PPH, the E-MOTIVE trial found that a multifaceted health service intervention reduced severe PPH after vaginal delivery by 60% in 78 hospitals in Nigeria, Kenya, Tanzania and SA. The E-MOTIVE approach comprises objective blood loss measurement monitored every 15 minutes during the first hour after delivery to detect PPH early and trigger a bundle of first-line treatments, including massaging the uterus, oxytocin infusion, tranexamic acid infusion, intravenous crystalloid fluids, examination for the cause, emptying the bladder and, if necessary, escalation of care...
December 4, 2023: South African Medical Journal
https://read.qxmd.com/read/38525412/advances-in-human-centered-care-to-address-contemporary-unmet-needs-in-chronic-dialysis
#34
REVIEW
Sumedh Jayanti, Gopala K Rangan
Advances in the treatment of kidney failure with chronic dialysis have stagnated over the past three decades, with over 50% of patients still managed by conventional in-hospital haemodialysis. In parallel, the demands of chronic dialysis medical care have changed and evolved due to a growing population that has higher frailty and multimorbidity. Thus, the gap between the needs of kidney failure patients and the healthcare capability to provide effective overall management has widened. To address this problem, healthcare policy has increasingly aligned towards a human-centred approach...
2024: International Journal of Nephrology and Renovascular Disease
https://read.qxmd.com/read/38523083/therapeutic-drug-monitoring-liquid-biopsies-or-pharmacogenomics-for-prediction-of-human-drug-metabolism-and-response
#35
REVIEW
Magnus Ingelman-Sundberg, Espen Molden
Pharmacokinetics plays a central role in understanding the significant interindividual differences that exist in drug metabolism and response. Effectively addressing these differences requires a multi-faceted approach that encompasses a variety of tools and methods. In this review, we examine three key strategies to achieve this goal, namely pharmacogenomics, therapeutic drug monitoring (TDM) and liquid biopsy-based monitoring of hepatic ADME gene expression and highlight their advantages and limitations. We note that larger cohort studies are needed to validate the utility of liquid biopsy-based assessment of hepatic ADME gene expression, which includes prediction of drug metabolism in the clinical setting...
March 24, 2024: British Journal of Clinical Pharmacology
https://read.qxmd.com/read/38521190/hepatic-adenoma-evolution-of-a-more-individualized-treatment-approach
#36
REVIEW
Hassan Aziz, Patrick W Underwood, Matthew D Gosse, Shadi Afyouni, Ihab Kamel, Timothy M Pawlik
BACKGROUND: Hepatic adenomas (HAs) are benign, solid liver lesions, which carry a risk of hemorrhage and malignant transformation. In this review article, we highlight advances in the diagnosis and management of HAs. METHODS: A comprehensive review was performed utilizing MEDLINE/PubMed and Web of Science databases with a search period ending September 30, 2023. Using PubMed, the terms "hepatocellular," "hepatic," and "adenoma" were searched. RESULTS: HA has been classified into at least eight subtypes based on molecular pathology, each exhibiting unique histopathological features, clinical considerations, and risk of malignant transformation...
March 16, 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38521086/pembrolizumab-or-placebo-with-chemoradiotherapy-followed-by-pembrolizumab-or-placebo-for-newly-diagnosed-high-risk-locally-advanced-cervical-cancer-engot-cx11-gog-3047-keynote-a18-a-randomised-double-blind-phase-3-clinical-trial
#37
JOURNAL ARTICLE
Domenica Lorusso, Yang Xiang, Kosei Hasegawa, Giovanni Scambia, Manuel Leiva, Pier Ramos-Elias, Alejandro Acevedo, Vladyslav Sukhin, Noelle Cloven, Andrea J Pereira de Santana Gomes, Fernando Contreras Mejía, Ari Reiss, Ali Ayhan, Jung-Yun Lee, Valeriya Saevets, Flora Zagouri, Lucy Gilbert, Jalid Sehouli, Ekkasit Tharavichitkul, Kristina Lindemann, Roberta Lazzari, Chih-Long Chang, Rudolf Lampé, Hong Zhu, Ana Oaknin, Melissa Christiaens, Stephan Polterauer, Tomoka Usami, Kan Li, Karin Yamada, Sarper Toker, Stephen M Keefe, Sandro Pignata, Linda R Duska
BACKGROUND: Pembrolizumab has shown efficacy in persistent, recurrent, or metastatic cervical cancer. The effect of chemoradiotherapy might be enhanced by immunotherapy. In this phase 3 trial, we assessed the efficacy and safety of adding pembrolizumab to chemoradiotherapy in locally advanced cervical cancer. METHODS: In this randomised, double-blind, placebo-controlled, phase 3 ENGOT-cx11/GOG-3047/KEYNOTE-A18 clinical trial, adults (age ≥18 years) at 176 medical centres in 30 countries with newly diagnosed, high-risk, locally advanced cervical cancer were randomly assigned (1:1) using an interactive voice-response system with integrated web response to receive 5 cycles of pembrolizumab (200 mg) or placebo every 3 weeks plus chemoradiotherapy, followed by 15 cycles of pembrolizumab (400 mg) or placebo every 6 weeks...
March 20, 2024: Lancet
https://read.qxmd.com/read/38520907/healthcare-5-0-a-secure-and-distributed-network-for-system-informatics-in-medical-surgery
#38
JOURNAL ARTICLE
Chenggang Wu, Yuk Ming Tang, Wei Ting Kuo, Ho Tung Yip, Ka Yin Chau
INTRODUCTION: Health records serve not only as a database of a patient's health history and treatment process but also as a crucial tool for doctors to diagnose and treat patients. However, the storage and sharing of these records are sensitive issues as they involve maintaining patient privacy and ensuring data transparency, security, and interoperability between different parties. Challenges to achieving these goals in the current surgical process can impact the allocation of medical resources and surgical outcomes...
March 20, 2024: International Journal of Medical Informatics
https://read.qxmd.com/read/38520030/peers-plus-mobile-app-for-treatment-in-hiv-path-protocol-for-a-randomized-controlled-trial-to-test-a-community-based-integrated-peer-support-and-mhealth-intervention-to-improve-viral-suppression-among-hispanic-and-black-people-living-with-hiv
#39
JOURNAL ARTICLE
Eileen V Pitpitan, Keith J Horvath, Jeannette Aldous, Jamila K Stockman, Thomas L Patterson, Megan Liang, Constantino Barrozo, Veronica Moore, Katherine Penninga, Laramie R Smith
BACKGROUND: Significant disparities continue to exist in the HIV care continuum, whereby Hispanic and Black people living with HIV (PLWH) are less likely to achieve viral suppression compared to their White counterparts. Studies have shown that intervention approaches that involve peer navigation may play an important role in supporting patients to stay engaged in HIV care. However, implementation may be challenging in real-world settings where there are limited resources to support peer navigators...
March 22, 2024: Trials
https://read.qxmd.com/read/38519983/lifestyle-counselling-as-secondary-prevention-in-patients-with-minor-stroke-or-transient-ischemic-attack-a-randomized-controlled-pilot-study
#40
JOURNAL ARTICLE
Jacob Liljehult, Stig Molsted, Tom Møller, Dorthe Overgaard, Thomas Christensen
BACKGROUND: Patients with minor stroke or transient ischemic attacks have an increased risk of future strokes. These patients are often discharged home with limited specialized follow-up, although close to half of them experience cognitive deficits. Simple encouragements to avoid smoking, be physically active, and to take preventive medication are often insufficient to ensure adherence and more comprehensive interventions are needed to support the patients in adapting healthy behaviour...
March 22, 2024: Pilot and Feasibility Studies
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