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Tdcs, Depression

Joan M Stilling, Oury Monchi, Farnaz Amoozegar, Chantel T Debert
BACKGROUND: Headache is among the most prevalent causes of disability worldwide. Non-pharmacologic interventions, including neuromodulation therapies, have been proposed in patients who are treatment resistant or intolerant to medications. OBJECTIVE: To perform a systematic review on the use of transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) for the treatment of specific headache disorders (ie, migraine, tension, cluster, posttraumatic)...
January 23, 2019: Headache
Farhad Taremian, Samira Nazari, Latif Moradveisi, Reza Moloodi
OBJECTIVES: Transcranial direct current stimulation can be effective in reducing the craving for food, alcohol, and methamphetamine. Because its effects have not been tested on patients with opium use disorder, we investigated its efficacy when it is combined with a standard methadone maintenance therapy protocol. METHODS: We carried out a pretest-posttest control group method to evaluate the effect of transcranial direct current stimulation at the dorsolateral prefrontal cortex (right anodal/left cathodal) on opium craving, depression, and anxiety symptoms...
January 16, 2019: Journal of ECT
Ho Yun Lee
Background: This study assessed the therapeutic effect of adjunctive bifrontal transcranial direct current stimulation (tDCS) in patients with tinnitus. Methods: Forty-four patients who visited our university hospital with a complaint of non-pulsatile subjective tinnitus in January through December 2016 were enrolled. All patients received directive counseling and sound therapy, such as a sound generator or hearing aids, and/or oral clonazepam. Patients who agreed to undergo additional bifrontal tDCS were classified as the study group (n = 26)...
January 21, 2019: Journal of Korean Medical Science
Mohaddeseh Hafez Yosephi, Fatemeh Ehsani, Maryam Daghiani, Maryam Zoghi, Shapour Jaberzadeh
Intensifying fear and fear of pain may lead to some diseases such as panic disorder, phobias, post-traumatic stress disorder (PTSD), anxiety disorders, depression, etc. A number of studies indicated positive effect of transcranial direct current stimulation (tDCS) on controlling fear and some studies did not observe any effect or even negative effect on decreasing fear. Due to lack of consensus in the findings of research, we aimed to systematically review studies, which investigated the effect of tDCS on fear...
January 16, 2019: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Luana V M Aparicio, Vivianne Rosa, Lais M Razza, Bernardo Sampaio-Junior, Lucas Borrione, Leandro Valiengo, Paulo A Lotufo, Isabela M Benseñor, Renerio Fraguas, Adriano H Moffa, Wagner F Gattaz, André Russowsky Brunoni
BACKGROUND: The efficacy of transcranial direct current stimulation (tDCS) as a continuation therapy for the maintenance phase of the depressive episode is low and insufficiently investigated in literature. We investigated whether it could be enhanced by using a more intensive treatment regimen compared to previous reports. METHODS: Twenty-four patients (16 with unipolar depression and eight with bipolar depression) who presented acute tDCS response (≥50% depression improvement in the Hamilton Depression Rating Scale [HDRS]) after receiving 15 tDCS sessions were followed for up to 6 months or until relapse, defined as clinical worsening and/or HDRS > 15...
January 14, 2019: Depression and Anxiety
Francis O'Neill, Paul Sacco, Eleanor Bowden, Rebecca Asher, Girvan Burnside, Trevor Cox, Turo Nurmikko
Background: Successful response to repetitive transcranial magnetic stimulation (rTMS) of the motor cortex requires continued maintenance treatments. Transcranial Direct Current Stimulation (tDCS) may provide a more convenient alternative. Methods: This pilot study aimed to examine the feasibility of a randomized, double-blind, double-crossover pilot study for patients to self-administer tDCS motor cortex stimulation for 20 minutes/day over five consecutive days...
2018: Journal of Pain Research
Ulrich Palm, Jérôme Brunelin, Linda Wulf, Marine Mondino, Andre R Brunoni, Frank Padberg
More than 40 % of patients with obsessive-compulsive disorder (OCD) do not respond to established treatments despite advances in psychopharmacology and psychotherapy. Since a couple of years, non-invasive brain stimulation techniques gain importance in the treatment of psychiatric disorders. Transcranial direct current stimulation (tDCS) uses weak constant direct current to modulate neuronal activation and changes the function of neuronal networks. This technique is recently investigated for the improvement of treatment resistant OCD symptoms...
December 11, 2018: Fortschritte der Neurologie-Psychiatrie
Bryan Dobbs, Natalie Pawlak, Milton Biagioni, Shashank Agarwal, Michael Shaw, Giuseppina Pilloni, Marom Bikson, Abhishek Datta, Leigh Charvet
BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that has been shown to improve common symptoms of neurological disorders like depressed mood, fatigue, motor deficits and cognitive dysfunction. tDCS requires daily treatment sessions in order to be effective. We developed a remotely supervised tDCS (RS-tDCS) protocol for participants with multiple sclerosis (MS) to increase accessibility of tDCS, reducing clinician, patient, and caregiver burden...
December 7, 2018: Journal of Neuroengineering and Rehabilitation
Nya Mehnwolo Boayue, Gábor Csifcsák, Oula Puonti, Axel Thielscher, Matthias Mittner
During the past decade, it became clear that the effects of non-invasive brain stimulation (NIBS) techniques such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are substantially influenced by variations in individual head and brain anatomy. In addition to structural variations in the healthy, several psychiatric disorders are characterized by anatomical alterations that are likely to further constrain the intracerebral effects of NIBS. Here, we present high-resolution realistic head models derived from structural magnetic resonance imaging data of 19 healthy adults and 19 patients diagnosed with major depressive disorder (MDD)...
2018: F1000Research
Anne Sauvaget, Agathe Tostivint, François Etcheverrigaray, Anne Pichot, Cécile Dert, Solène Schirr-Bonnais, Johann Clouet, Olivier Sellal, Nicolas Mauduit, Christophe Leux, Clémence Cabelguen, Samuel Bulteau, Valéry-Pierre Riche
OBJECTIVES: Due to its ease of use, tolerance, and cost of acquisition, transcranial direct current stimulation (tDCS) could constitute a credible therapeutic option for non-resistant depression in primary care, when combined with drug management. This indication has yet to receive official recognition in France. The objective of this study is to evaluate the production cost of tDCS for the treatment of depression in hospitals, under realistic conditions. METHODS: The methodology adopted is based on cost accounting and was validated by a multidisciplinary working group...
November 27, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Hikmat Hadoush, Alham Al-Sharman, Hanan Khalil, Saleem A Banihani, Muhammed Al-Jarrah
BACKGROUND Sleep dysfunctions impose a large burden on quality of life for patients with Parkinson's disease (PD). Several studies on PD reported potential therapeutic effects of transcranial direct current stimulation (tDCS) on motor and non-motor functions, but not related to sleep quality. Therefore, the present study examined sleep quality, depression perception, and quality of life changes after bilateral anodal tDCS in patients with PD. MATERIAL AND METHODS Twenty-one patients (n=21) with PD underwent 10 sessions (20 min each, 5 per week) of bilateral anodal tDCS stimulation applied simultaneously over the left and right prefrontal and motor areas...
November 19, 2018: Medical Science Monitor Basic Research
Sang Hoon Lee, Jooyeon Jamie Im, Jin Kyoung Oh, Eun Kyoung Choi, Sujung Yoon, Marom Bikson, In-Uk Song, Hyeonseok Jeong, Yong-An Chung
AIM: Excessive use of online games can have negative influences on mental health and daily functioning. Although the effects of transcranial direct current stimulation (tDCS) have been investigated for the treatment of addiction, it has not been evaluated for excessive online game use. This study aimed to investigate the feasibility and tolerability of tDCS over the dorsolateral prefrontal cortex (DLPFC) in online gamers. METHODS: A total of 15 online gamers received 12 active tDCS sessions over the DLPFC (anodal left/cathodal right, 2 mA for 30 min, 3 times per week for 4 weeks)...
November 12, 2018: Journal of Behavioral Addictions
Mark Corbett, Emily South, Melissa Harden, Sam Eldabe, Erlick Pereira, Imad Sedki, Neil Hall, Nerys Woolacott
BACKGROUND: Although many treatments exist for phantom limb pain (PLP), the evidence supporting them is limited and there are no guidelines for PLP management. Brain and spinal cord neurostimulation therapies are targeted at patients with chronic PLP but have yet to be systematically reviewed. OBJECTIVE: To determine which types of brain and spinal stimulation therapy appear to be the best for treating chronic PLP. DESIGN: Systematic reviews of effectiveness and epidemiology studies, and a survey of NHS practice...
November 2018: Health Technology Assessment: HTA
Yeganeh Shahsavar, Majid Ghoshuni, Ali Talaei
The main goal of this study was to assess the changes in brain activities of patients with severe depression by applying transcranial direct current stimulation (tDCS) using event related potentials (ERPs). Seven patients (four males, with the mean age 34.85 ± 4.25) were asked to fill out Beck's depression questionnaires. EEG signals of subjects were recorded during Stroop test. This test entailed 360 stimulations, which included 120 congruent, 120 incongruent, and 120 neutral stimulations lasting for 12 min...
December 2018: Australasian Physical & Engineering Sciences in Medicine
Daniel L Kenney-Jung, Caren J Blacker, Deniz Doruk Camsari, Jonathan C Lee, Charles P Lewis
Transcranial direct current stimulation (tDCS) involves the application of weak electric current to the scalp. tDCS may influence brain functioning through effects on cortical excitability, neural plasticity, and learning. Evidence in adults suggests promising therapeutic applications for depression, and the adverse effect profile is generally mild. Early research indicates complex interactions between tDCS and concurrent cognitive and motor tasks. Further investigation is warranted to understand how tDCS impacts processes relevant to psychiatric conditions...
January 2019: Child and Adolescent Psychiatric Clinics of North America
Ahmet Zihni Soyata, Serkan Aksu, Adam J Woods, Pınar İşçen, Kardelen Türkü Saçar, Sacit Karamürsel
Decision making and cognitive flexibility are two components of cognitive control that play a critical role in the emergence, persistence, and relapse of gambling disorder. Transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) has been reported to enhance decision making and cognitive flexibility in healthy volunteers and individuals with addictive disorders. In this triple-blind randomized sham-controlled parallel study, we aimed to determine whether tDCS over DLPFC would modulate decision making and cognitive flexibility in individuals with gambling disorder...
October 26, 2018: European Archives of Psychiatry and Clinical Neuroscience
Tifei Yuan, Ali Yadollahpour, Julio Salgado-Ramírez, Daniel Robles-Camarillo, Rocío Ortega-Palacios
BACKGROUND: Tinnitus is the perception of sound in the absence of any external acoustic stimulation. Transcranial direct current stimulation (tDCS) has shown promising though heterogeneous therapeutic outcomes for tinnitus. The present study aims to review the recent advances in applications of tDCS for tinnitus treatment. In addition, the clinical efficacy and main mechanisms of action of tDCS on suppressing tinnitus are discussed. METHODS: The study was performed in accordance with the PRISMA guidelines...
October 25, 2018: BMC Neuroscience
Timothy Y Mariano, Frederick W Burgess, Marguerite Bowker, Jason Kirschner, Mascha Van't Wout-Frank, Richard N Jones, Christopher W Halladay, Michael Stein, Benjamin D Greenberg
Background and Objective: Chronic low back pain (CLBP) is highly prevalent, with a substantial psychosocial burden. Pain has both sensory and affective components. The latter component is a significant driver of disability and psychiatric comorbidity but is often inadequately treated. Previously we reported that noninvasive transcranial direct current stimulation (tDCS) may modulate pain-associated affective distress. Here we tested whether 10 daily tDCS sessions aimed to inhibit the left dorsal anterior cingulate cortex (dACC), a region strongly implicated in the affective component of pain, would produce selective reduction in pain-related symptoms...
October 24, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Maria Ironside, Michael Browning, Tahereh L Ansari, Christopher J Harvey, Mama N Sekyi-Djan, Sonia J Bishop, Catherine J Harmer, Jacinta O'Shea
Importance: Transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC) is under clinical investigation as a treatment for major depressive disorder. However, the mechanisms of action are unclear, and there is a lack of neuroimaging evidence, particularly among individuals with affective dysfunction. Furthermore, there is no direct causal evidence among humans that the prefrontal-amygdala circuit functions as described in animal models (ie, that increasing activity in prefrontal cortical control regions inhibits amygdala response to threat)...
October 17, 2018: JAMA Psychiatry
Andre R Brunoni, Bernardo Sampaio-Junior, Adriano H Moffa, Luana V Aparício, Pedro Gordon, Izio Klein, Rosa M Rios, Lais B Razza, Colleen Loo, Frank Padberg, Leandro Valiengo
OBJECTIVE: Noninvasive brain stimulation (NIBS) techniques, such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), are increasingly being used to treat mental disorders, particularly major depression. The aim of this comprehensive review is to summarize the main advances, limitations, and perspectives of the field. METHODS: We searched PubMed and other databases from inception to July 2017 for articles, particularly systematic reviews and meta-analyses, evaluating the use of NIBS in psychiatric disorders...
October 11, 2018: Revista Brasileira de Psiquiatria
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