keyword
https://read.qxmd.com/read/36337701/effect-of-music-based-movement-therapy-on-the-freezing-of-gait-in-patients-with-parkinson-s-disease-a-randomized-controlled-trial
#21
JOURNAL ARTICLE
Kun-Peng Li, Zeng-Qiao Zhang, Zong-Lei Zhou, Jian-Qing Su, Xian-Hua Wu, Bo-Han Shi, Jian-Guang Xu
BACKGROUND: Progression of freezing of gait (FOG), a common pathological gait in Parkinson's disease (PD), has been shown to be an important risk factor for falls, loss of independent living ability, and reduced quality of life. However, previous evidence indicated poor efficacy of medicine and surgery in treating FOG in patients with PD. Music-based movement therapy (MMT), which entails listening to music while exercising, has been proposed as a treatment to improve patients' motor function, emotions, and physiological activity...
2022: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/35992946/influence-of-sagittal-pelvic-attitude-on-gait-pattern-in-normally-developed-people-and-interactions-with-neurological-pathologies-a-pilot-study
#22
JOURNAL ARTICLE
Martina Favetta, Alberto Romano, Susanna Summa, Alessandra Colazza, Silvia Minosse, Gessica Vasco, Enrico Castelli, Maurizio Petrarca
Background: Gait Analysis of healthy people, imitating pathological conditions while walking, has increased our understanding of biomechanical factors. The influence of the pelvis as a biomechanical constraint during gait is not specifically studied. How could mimicking a pelvic attitude influence the dynamic mechanical interaction of the body segments? We proposed an investigation of the pelvic attitude role on the gait pattern of typically developed people when they mimicked pelvic anteversion and posteroversion...
2022: Frontiers in Human Neuroscience
https://read.qxmd.com/read/35983318/disseminated-zoster-involving-the-whole-body-in-an-immunocompetent-patient-complaining-of-left-leg-radiating-pain-and-weakness-a-case-report-and-literature-review
#23
Young-Seok Moon, Wan-Jae Cho, Youn-Sung Jung, Jun-Seok Lee
Introduction: Disseminated herpes zoster is defined as at least 20 skin lesions in multiple dermatomes. In particular, it has been reported mainly in patients with immunological defects. To our knowledge, there is no reported case of disseminated zoster in a non-immunocompromised patient with leg radiating pain and weakness. Case presentation: A 74-year-old man visited our hospital with left leg radiating pain and left hip pain. He had no underlying disease other than hypertension...
2022: Geriatric Orthopaedic Surgery & Rehabilitation
https://read.qxmd.com/read/35918325/pudendal-tumor-mimicking-cauda-equina-syndrome-and-acute-radiculopathy-case-report
#24
JOURNAL ARTICLE
Uma V Mahajan, Kyle B Labak, Collin M Labak, Eric Z Herring, Kyle Lineberry, Jonathan P Miller, Gabriel Smith
INTRODUCTION: Cauda equina syndrome (CES) is most caused by lumbar disc herniation, and the associated treatment involves prompt surgical decompression. Rarer causes of CES include perineural (Tarlov) cysts. CLINICAL PRESENTATION: A 62-year-old female with history of rheumatoid arthritis, hip and knee replacements, and chronic low back pain presented with worsening back pain, left leg weakness and pain for 6 weeks, and bowel/bladder incontinence with diminished sensation in the perianal region for 24 h prior to presentation...
August 2, 2022: Spinal Cord Series and Cases
https://read.qxmd.com/read/35854321/effects-of-atlas-2030-gait-exoskeleton-on-strength-and-range-of-motion-in-children-with-spinal-muscular-atrophy-ii-a-case-series
#25
JOURNAL ARTICLE
C Cumplido-Trasmonte, J Ramos-Rojas, E Delgado-Castillejo, E Garcés-Castellote, G Puyuelo-Quintana, M A Destarac-Eguizabal, E Barquín-Santos, A Plaza-Flores, M Hernández-Melero, A Gutiérrez-Ayala, M Martínez-Moreno, E García-Armada
BACKGROUND: Children with spinal muscular atrophy (SMA) present muscle weakness and atrophy that results in a number of complications affecting their mobility, hindering their independence and the development of activities of daily living. Walking has well-recognized physiological and functional benefits. The ATLAS 2030 exoskeleton is a paediatric device that allows gait rehabilitation in children with either neurological or neuromuscular pathologies with gait disorders. The purpose is to assess the effects in range of motion (ROM) and maximal isometric strength in hips, knees and ankles of children with SMA type II after the use of ATLAS 2030 exoskeleton...
July 19, 2022: Journal of Neuroengineering and Rehabilitation
https://read.qxmd.com/read/35741282/secondary-late-developmental-dysplasia-of-the-hip-with-displacement-from-case-studies-to-a-proposition-for-a-modified-diagnostic-path
#26
Jacek Dygut, Jerzy Sułko, Ibeth Guevara-Lora, Monika Piwowar
(1) Background. This paper presents a case of hip joints that were initially described as either normal or physiologically immature in four successive ultrasound examinations using the static method by Graf; however, the final treatment of the patient involved multiple hip reconstruction surgeries. (2) Case presentation. The patient was born with an Apgar score of 10 and did not exhibit neurological diseases that could deform and lead to pathological dislocation of the right hip joint. The subsequent analysis of medical data revealed that the hip luxation was due to secondary (late) developmental dysplasia of the right hip...
June 15, 2022: Diagnostics
https://read.qxmd.com/read/35666487/incidence-and-risk-factors-for-concurrent-syndromic-diagnosis-in-presumed-idiopathic-developmental-dysplasia-of-the-hip
#27
JOURNAL ARTICLE
F Keith Gettys, Adriana De La Rocha, Brandon A Ramo
BACKGROUND: Infants referred for developmental dysplasia of the hip (DDH) may have a previously unidentified concomitant diagnosis of syndromic pathology. Our purpose was to examine the incidence of syndromic pathology in infants referred to a tertiary center with presumed idiopathic DDH and identify risk factors and difference in treatment courses between idiopathic and nonidiopathic cohorts. METHODS: A retrospective analysis of a prospective cohort of infants younger than 3 years who were evaluated for DDH between 2008 and 2013 with a minimum 2-year follow-up...
June 1, 2022: Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews
https://read.qxmd.com/read/35621394/proteins-and-proteases-of-prader-willi-syndrome-a-comprehensive-review-and-perspectives
#28
REVIEW
Sanjukta Basak, Ajoy Basak
Prader-Willi Syndrome (PWS) is a rare complex genetic disease that is associated with pathological disorders that include endocrine disruption, developmental, neurological, and physical problems as well as intellectual, and behavioral dysfunction. In early stage, PWS is characterized by respiratory distress, hypotonia, and poor sucking ability, causing feeding concern and poor weight gain. Additional features of the disease evolve over time. These include hyperphagia, obesity, developmental, cognitive delay, skin picking, high pain threshold, short stature, growth hormone deficiency, hypogonadism, strabismus, scoliosis, joint laxity, or hip dysplasia...
June 30, 2022: Bioscience Reports
https://read.qxmd.com/read/35605310/quantitative-three-dimensional-gait-evaluation-in-patients-with-glucose-transporter-1-deficiency-syndrome
#29
JOURNAL ARTICLE
Takeshi Suzuki, Yuji Ito, Tadashi Ito, Hiroyuki Kidokoro, Koji Noritake, Ayako Hattori, Shin Nabatame, Jun Natsume
BACKGROUND: Of the patients with glucose transporter 1 deficiency syndrome (GLUT1-DS), 90% have a pathologic gait. Ataxic-spastic and ataxic gaits are seen in 35% of patients each. A ketogenic diet and modified Atkins diet (MAD) are effective therapy in GLUT1-DS in terms of both the seizures and movement disorder. A three-dimensional gait analysis (3DGA) system can be used to evaluate gait quantitatively using spatiotemporal data and gait kinematics. We performed 3DGA in three ambulatory patients with GLUT1-DS to evaluate the characteristics of their gait pathology, and we compared the gait variables before and after enhancing the MAD in one patient...
July 2022: Pediatric Neurology
https://read.qxmd.com/read/35537562/sanfilippo-syndrome-type-a-early-cardiac-involvement-of-two-patients-with-cardiac-manifestations
#30
Marcia Ballantyne, Brian Chiu, Consolato M Sergi
PURPOSE: To report two unusual presentations of mucopolysaccharidosis type III (Sanfilippo syndrome) and provide evidence for the cardiac involvement. PATIENTS AND METHODS: We report two siblings with cardiac involvement that were diagnosed in childhood with Sanfilippo A Syndrome (SAS). All patients' diagnosis was confirmed by the excess of heparan sulfate in the urine and the reduction of heparan sulphamidase protein activity. The heart specimens were studied. RESULTS: We report two sibling patients (15-years-old female and 12-years-old female) occurring in sisters both with onset in childhood with no neurological, ophthalmic, hepatic symptoms or coarsening of features as classically described...
May 7, 2022: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://read.qxmd.com/read/35462862/coxofemoral-luxation-as-a-complication-of-localised-tetanus-in-a-cat
#31
Cecilia-Gabriella Danciu, Joshua Milgram, Ciprian Andrei Ober, Flaviu Alexandru Tăbăran, Helga Demény, Orit Chai
Case summary: A 9-month-old male neutered domestic shorthair cat presented 2 weeks after castration with a 48 h history of acute-onset lateral recumbency and severe hindlimb rigidity. Physical examination findings included hyperthermia, tachypnoea, hindlimb rigidity and a healed orchidectomy site. Neurological examination of the head and forelimbs was normal; however, there was a spastic, non-ambulatory paraparesis of the hindlimbs, which was more severe on the left. Abnormal findings included mildly elevated serum creatine kinase levels and on electromyography there was bilateral pathological spontaneous activity of the biceps femoris muscles...
January 2022: JFMS Open Reports
https://read.qxmd.com/read/35458954/performance-of-deep-learning-models-in-forecasting-gait-trajectories-of-children-with-neurological-disorders
#32
JOURNAL ARTICLE
Rania Kolaghassi, Mohamad Kenan Al-Hares, Gianluca Marcelli, Konstantinos Sirlantzis
Forecasted gait trajectories of children could be used as feedforward input to control lower limb robotic devices, such as exoskeletons and actuated orthotic devices (e.g., Powered Ankle Foot Orthosis-PAFO). Several studies have forecasted healthy gait trajectories, but, to the best of our knowledge, none have forecasted gait trajectories of children with pathological gait yet. These exhibit higher inter- and intra-subject variability compared to typically developing gait of healthy subjects. Pathological trajectories represent the typical gait patterns that rehabilitative exoskeletons and actuated orthoses would target...
April 13, 2022: Sensors
https://read.qxmd.com/read/35036015/tumoral-calcinosis-of-the-cervical-spine-associated-with-a-pathologic-odontoid-fracture
#33
Andy Y Wang, Joseph N Tingen, Eric J Mahoney, Ron I Riesenburger
Tumoral calcinosis involves focal calcium deposits in the soft tissues surrounding a joint and most commonly occurs in the hips and elbows, rarely in the cervical spine. Furthermore, it has not been known to be associated with pathologic fractures. To the best of our knowledge, our case report highlights the first case of a pathologic type II odontoid fracture associated with adjacent tumoral calcinosis, resulting in pain, dysphagia, and severe spinal stenosis. The patient underwent a posterior occipitocervical fusion and C1 laminectomy, along with planned tracheostomy and gastrostomy to avoid expected difficulty with postoperative extubation and dysphagia...
2022: Case Reports in Neurological Medicine
https://read.qxmd.com/read/34925648/increased-serum-neuropeptide-galanin-level-is-a-predictor-of-cognitive-dysfunction-in-patients-with-hip-fracture
#34
JOURNAL ARTICLE
Zichao Xue, Ke Zhang, Biao Luo, Long Fan, Ruizhe Zhao, Guangliang Hu
Background: Hip fracture is a common occurrence in elderly populations and is frequently followed by various levels of cognitive dysfunction, leading to adverse functional outcomes. Risk stratification of hip fracture patients to identify high-risk subsets can enable improved strategies to mitigate cognitive complications. The neuropeptide galanin has multiple neurological functions, and altered levels are documented in dementia-type and depression disorders. The present study investigated the association of serum neuropeptide galanin levels in hip fracture patients with the occurrence of cognitive dysfunction during the first week of admission...
2021: Disease Markers
https://read.qxmd.com/read/34924553/reciprocal-interaction-between-depression-and-pain-results-from-a-comprehensive-bidirectional-mendelian-randomization-study-and-functional-annotation-analysis
#35
JOURNAL ARTICLE
Bowen Tang, Weihua Meng, Sara Hägg, Stephen Burgess, Xia Jiang
To understand a putative causal link for depression and pain, we retrieved summary statistics from genome-wide association studies conducted for pain at 7 different body sites (N = 151,922-226,683) and major depression disorder (MDD, Ncase/control = 246,363/561,190). We conducted a bidirectional Mendelian randomization analysis using distinct genome-wide association studies-identified single nucleotide polymorphisms for each trait as instrumental variables and performed several sensitivity analyses to verify Mendelian randomization assumptions...
January 1, 2022: Pain
https://read.qxmd.com/read/34902658/unilateral-non-electric-assistive-walking-device-helps-neurological-and-orthopedic-patients-to-improve-gait-patterns
#36
JOURNAL ARTICLE
Boris Feodoroff, Vera Blümer
BACKGROUND: Pathological gait patterns are common in neurological and orthopedic patients. These put them at risk of falling and restrict their autonomy and social participation. Novel assistive walking devices are designed to actively support physiological gait patterns by means of motor guidance and mechanical support of the lower limbs. RESEARCH QUESTION: Does a non-electric assistive walking device powered by a cam-spring mechanism (aLQ, Imasen) improve or otherwise affect pathological gait patterns in neurological and orthopedic patients? METHODS: A three-dimensional instrumented gait analysis was conducted on a treadmill (quasar, hp cosmos) using spatiotemporal, kinetic, and kinematic data obtained from synchronized motion capturing (Miqus M3, Qualisys), surface EMG (sEMG; Ultium, Noraxon), and pressure distribution measurements (FMD-T, Zebris)...
February 2022: Gait & Posture
https://read.qxmd.com/read/34900862/atlas2030-pediatric-gait-exoskeleton-changes-on-range-of-motion-strength-and-spasticity-in-children-with-cerebral-palsy-a-case-series-study
#37
JOURNAL ARTICLE
Elena Delgado, Carlos Cumplido, Jaime Ramos, Elena Garcés, Gonzalo Puyuelo, Alberto Plaza, Mar Hernández, Alba Gutiérrez, Thomas Taverner, Marie André Destarac, Mercedes Martínez, Elena García
Background: Cerebral Palsy (CP), the most common motor disability in childhood, affects individual's motor skills, movement and posture. This results in limited activity and a low social participation. The ATLAS2030 exoskeleton is a pediatric device that enables gait rehabilitation for children with neurological or neuromuscular pathologies with gait pathology. Purpose: To study changes in relation to range of motion (ROM), strength and spasticity in children with CP after using the ATLAS2030 gait exoskeleton...
2021: Frontiers in Pediatrics
https://read.qxmd.com/read/34686356/parkinsonism-and-cerebrovascular-disease
#38
REVIEW
Manisha Narasimhan, Raymond Schwartz, Glenda Halliday
The relationship between cerebrovascular disease and parkinsonism is commonly seen in everyday clinical practice but remains ill-defined and under-recognised with little guidance for the practising neurologist. We attempt to define this association and to illustrate key clinical, radiological and pathological features of the syndrome of Vascular Parkinsonism (VaP). VaP is a major cause of morbidity in the elderly associated with falls, hip fractures and cognitive impairment. Although acute parkinsonism is reported in the context of an acute cerebrovascular event, the vast majority of VaP presents as an insidious syndrome usually in the context of vascular risk factors and radiological evidence of small vessel disease...
February 15, 2022: Journal of the Neurological Sciences
https://read.qxmd.com/read/34485422/a-comparison-of-two-dimensional-and-three-dimensional-techniques-for-kinematic-analysis-of-the-sagittal-motion-of-sheep-hindlimbs-during-walking-on-a-treadmill
#39
JOURNAL ARTICLE
Camila Cardoso Diogo, José Arthur Camassa, Bárbara Fonseca, Luís Maltez da Costa, José Eduardo Pereira, Vítor Filipe, Pedro Alexandre Couto, Stefania Raimondo, Paulo A Armada-da-Silva, Ana Colette Maurício, Artur S P Varejão
Compared to rodents, sheep offer several attractive features as an experimental model for testing different medical and surgical interventions related to pathological gait caused by neurological diseases and injuries. To use sheep for development of novel treatment strategies in the field of neuroscience, it is key to establish the relevant kinematic features of locomotion in this species. To use sheep for development of novel treatment strategies in the field of neuroscience, it is crucial to understand fundamental baseline characteristics of locomotion in this species...
2021: Frontiers in Veterinary Science
https://read.qxmd.com/read/34484949/diskogenic-dural-defect-is-the-reason-for-the-ventral-location-of-the-epidural-spinal-fluid-collection-seen-in-superficial-siderosis
#40
REVIEW
Neeraj Kumar
Purpose of Review: Superficial siderosis (SS) of the nervous system is often due to a dural pathology. This review focuses on recent developments related to the management of this subgroup of patients with SS. Recent Findings: The presence of an epidural ventral spinal fluid collection in patients with SS is a clue to the presence of a diskogenic dural defect. The location of the defect is ascertained by a dynamic CT myelogram, which involves placing the patient in a prone position with hips elevated...
August 2021: Neurology. Clinical Practice
keyword
keyword
166914
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.