Elsa Dent, Jack Dalla Via, Trent Bozanich, Emiel O Hoogendijk, Abadi K Gebre, Cassandra Smith, Kun Zhu, Richard L Prince, Joshua R Lewis, Marc Sim
Frailty is associated with declines in physiological capacity across sensory, neurological, and musculoskeletal systems. An underlying assumption is that the frailer an individual, the more likely they are to experience falls and fractures. We examined whether grades of frailty can assess the long-term risk of hospitalized falls, fractures, and all-cause mortality in 1261 community-dwelling older women (mean age [SD] of 75.1 [2.7] yr) over 14.5 yr. Frailty was operationalized using a frailty index (FI) of cumulative deficits from 33 variables across multiple health domains (physical, mental, comorbidities) at baseline...
January 4, 2024: Journal of Bone and Mineral Research