Junjie Cheng, Li Li, Duo Jin, Yajie Zhang, Wenxin Yu, Jiaji Yu, Jianhua Zou, Yi Dai, Yang Zhu, Manman Liu, Miya Zhang, Yongfu Sun, Yangzhong Liu, Xiaoyuan Chen
Enzymes are considered safe and effective therapeutic tools for various diseases. With the increasing integration of biomedicine and nanotechnology, artificial nanozymes offer advanced controllability and functionality in medical design. However, several notable gaps, such as catalytic diversity, specificity and biosafety, still exist between nanozymes and their native counterparts. Here we report a non-metal single-selenium (Se)-atom nanozyme (SeSAE), which exhibits potent nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-mimetic activity...
February 15, 2024: Angewandte Chemie