keyword
https://read.qxmd.com/read/38630749/impact-of-tobacco-habits-on-poor-oral-health-status-among-bone-factory-workers-in-a-low-literacy-city-in-india-a-cross-sectional-study
#1
JOURNAL ARTICLE
Naved Alam, Warisha Mariam
Oral health is a vital indicator of well-being that is influenced by various habits and lifestyles of individuals. Oral diseases are the bottleneck in the effective control of non-communicable diseases (NCDs) due to chronic in nature and reciprocal relationship as sharing the common risk factors and habits such as sugar, tobacco, and alcohol consumption that increase the risk of developing various inevitable diseases. However, there is a lack of literature highlighting the relationship between risk factors for oral diseases and general health among individuals...
2024: PloS One
https://read.qxmd.com/read/38630563/every-body-gets-a-say-an-augmented-optimization-metric-to-preserve-body-pose-during-avatar-adaptation-in-mixed-augmented-reality
#2
JOURNAL ARTICLE
Alexandra Watkins, Akshith Ullal, Nilanjan Sarkar
User-Avatar interaction within augmented reality applications is rapidly increasing in frequency. Applications routinely place users in rooms with other, remote users embodied by photorealistic avatars, or require users to work with an avatar of a remote user to complete a task. During these types of interactions, it is often required to modify or redirect the posture of an avatar to achieve goals such as contact with or pointing at an object or maintaining eye gaze with the local user. A key limitation of modern redirection techniques is successfully preserving body posture, a critical component of nonverbal communication...
April 17, 2024: IEEE Transactions on Visualization and Computer Graphics
https://read.qxmd.com/read/38630530/a-smartphone-app-to-support-self-management-for-people-living-with-sj%C3%A3-gren-s-syndrome-qualitative-co-design-workshops
#3
JOURNAL ARTICLE
Claire McCallum, Miglena Campbell, John Vines, Tim Rapley, Jason Ellis, Vincent Deary, Katie Hackett
BACKGROUND: Sjögren's syndrome (SS) is the second most common autoimmune rheumatic disease, and the range of symptoms includes fatigue, dryness, sleep disturbances, and pain. Smartphone apps may help deliver a variety of cognitive and behavioral techniques to support self-management in SS. However, app-based interventions must be carefully designed to promote engagement and motivate behavior change. OBJECTIVE: We aimed to explore self-management approaches and challenges experienced by people living with SS and produce a corresponding set of design recommendations that inform the design of an engaging, motivating, and evidence-based self-management app for those living with SS...
April 17, 2024: JMIR Human Factors
https://read.qxmd.com/read/38630425/a-case-report-of-acute-claudication-due-to-vena-cava-thromboembolism-in-a-dog-naturally-infected-with-leishmania-infantum
#4
JOURNAL ARTICLE
Natalia Calvo-Sánchez, Álex Gómez, Estela Pérez, María Borobia, Lluís Luján, Antonio Fernández, Sergio Villanueva-Saz, Maite Verde, Diana Marteles
Canine leishmaniosis is a vector-borne disease caused by Leishmania infantum, and clinical manifestations of infection range from absent or severe to fatal and result from immune-mediated mechanisms. In dogs, the most common clinical signs of leishmaniosis include skin lesions and lymphadenomegaly. However, the presence of other nontypical signs has been described, and diagnosing these cases can be challenging. The aim of the present short communication was to describe the impact of the formation of circulating immunocomplexes due to L...
April 17, 2024: Veterinary Research Communications
https://read.qxmd.com/read/38629043/from-emotional-signals-to-symbols
#5
JOURNAL ARTICLE
Ulrike Griebel, D Kimbrough Oller
The quest for the origins of language is a diverse enterprise, where research from a variety of disciplines brings area-specific ideas and area-specific terminology to bear. This variety often results in misunderstandings and misconceptions about communication in various species. In the present paper, we argue for focus on emotional systems as the primary motivators for social signals in animals in general. This focus can help resolve discrepancies of interpretation among different areas of inquiry and can illuminate distinctions among different social signals as well as their phylogenetic origins in animals and especially in humans...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38628953/low-level-viremia-is-associated-with-serious-non-aids-events-in-people-with-hiv
#6
JOURNAL ARTICLE
Anuradha Ganesan, Hsing-Chuan Hsieh, Xiuping Chu, Rhonda E Colombo, Catherine Berjohn, Tahaniyat Lalani, Joseph Yabes, Christie A Joya, Jason Blaylock, Brian K Agan
BACKGROUND: The consequences of low-level viremia in people with HIV are unclear. We used data from the US Military HIV Natural History Study to examine the association of low-level viremia (LLV) and serious non-AIDS events (SNAEs). METHODS: Included participants initiated antiretroviral therapy after 1996 and had ≥3 viral loads (VLs) measured, using an assay with a lower limit of detection of <50 copies/mL, ≥6 months after antiretroviral therapy initiation...
April 2024: Open Forum Infectious Diseases
https://read.qxmd.com/read/38628719/university-teachers-perceptions-of-ict-based-teaching-to-construct-knowledge-for-effective-classroom-interaction-in-the-context-of-tpack-model
#7
JOURNAL ARTICLE
Muhammad Rashedul Huq Shamim, Ash Malick Jeng, Md Abu Raihan
The purpose of the research was to investigate university teachers' perceptions of information and communication technology (ICT) to enhance teaching and construct new knowledge. The objective was to determine how teachers at the University of the Gambia perceived the effectiveness of the TPACK (Technology, Pedagogy, and Content Knowledge) model in teaching through ICT and how different attributes of teachers affect their level of TPACK knowledge. This study used a questionnaire, adapted from the TPACK model, which was administered to 88 faculty selected purposively from the University of the Gambia to collect data on their level of awareness of ICT-based teaching...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38628570/connecting-stakeholder-priorities-and-desired-environmental-attributes-for-wetland-restoration-using-ecosystem-services-and-a-heat-map-analysis-for-communications
#8
JOURNAL ARTICLE
Connie L Hernandez, Leah M Sharpe, Chloe A Jackson, Matthew C Harwell, Theodore H DeWitt
Framing ecological restoration and monitoring goals from a human benefits perspective (i.e., ecosystem services) can help inform restoration planners, surrounding communities, and relevant stakeholders about the direct benefits they may obtain from a specific restoration project. We used a case study of tidal wetland restoration in the Tillamook River watershed in Oregon, USA, to demonstrate how to identify and integrate community stakeholders/beneficiaries and the environmental attributes they use to inform the design of and enhance environmental benefits from ecological restoration...
March 27, 2024: Frontiers in Ecology and Evolution
https://read.qxmd.com/read/38628111/rapid-response-teams-in-the-eastern-mediterranean-region-results-from-the-baseline-survey-of-country-level-capacities-operations-and-outbreak-response-capabilities
#9
JOURNAL ARTICLE
Sherein Elnosserry, Evans Buliva, Amgad Abdalla Elkholy, Amira Mahboob, Shaffi Fazaludeen Koya, Abdinasir Abubakar
The aim of this study is to assess WHO/Eastern Mediterranean region (WHO/EMR) countries capacities, operations and outbreak response capabilities. Cross-sectional study was conducted targeting 22 WHO/EMR countries from May to June 2021. The survey covers 8 domains related to 15 milstones and key performance indicators (KPIs) for RRT. Responses were received from 14 countries. RRTs are adequately organised in 9 countries (64.3%). The mean retention rate of RRT members was 85.5% ± 22.6. Eight countries (57...
January 2024: Global Public Health
https://read.qxmd.com/read/38627834/the-implementation-of-embedded-researchers-in-policy-public-services-and-commercial-settings-a-systematic-evidence-and-gap-map
#10
JOURNAL ARTICLE
Dylan Kneale, Claire Stansfield, Rebecca Goldman, Sarah Lester, Rachael C Edwards, James Thomas
BACKGROUND: Embedding researchers into policy and other settings may enhance research capacity within organisations to enable them to become more research active. We aimed to generate an evidence map on evaluations of embedded researcher interventions to (i) identify where systematic reviews and primary research are needed and (ii) develop conceptual understandings of 'embedded researchers'. We define 'embedded researchers' through a set of principles that incorporate elements such as the aim of activities, the types of relationships and learning involved, and the affiliations and identities adopted...
April 16, 2024: Implementation science communications
https://read.qxmd.com/read/38627796/increased-levels-of-villus-derived-exosomal-mir-29a-3p-in-normal-pregnancy-than-urpl-patients-suppresses-decidual-nk-cell-production-of-interferon-%C3%AE-and-exerts-a-therapeutic-effect-in-abortion-prone-mice
#11
JOURNAL ARTICLE
Zheng Fang, Jiaqin Mao, Jialyu Huang, Huijun Sun, Xueyan Lu, Hui Lei, Jie Dong, Shuqiang Chen, Xiaohong Wang
OBJECTIVE: Recurrent pregnancy loss (RPL) patients have higher absolute numbers of decidual natural killer (dNK) cells with elevated intracellular IFN-γ levels leading to a pro-inflammatory cytokine milieu, which contributes to RPL pathogenesis. The main objective of this study was twofold: first to explore the regulatory effects and mechanisms of villus-derived exosomes (vEXOs) from induced abortion patients or RPL patients at the level of intracellular IFN-γ in dNK cells; second to determine the validity of application of vEXOs in the treatment of unexplained RPL (uRPL) through in vitro experiments and mouse models...
April 16, 2024: Cell Communication and Signaling: CCS
https://read.qxmd.com/read/38627598/a-spatiotemporal-atlas-of-mouse-liver-homeostasis-and-regeneration
#12
JOURNAL ARTICLE
Jiangshan Xu, Pengcheng Guo, Shijie Hao, Shuncheng Shangguan, Quan Shi, Giacomo Volpe, Keke Huang, Jing Zuo, Juan An, Yue Yuan, Mengnan Cheng, Qiuting Deng, Xiao Zhang, Guangyao Lai, Haitao Nan, Baihua Wu, Xinyi Shentu, Liang Wu, Xiaoyu Wei, Yujia Jiang, Xin Huang, Fengyu Pan, Yumo Song, Ronghai Li, Zhifeng Wang, Chuanyu Liu, Shiping Liu, Yuxiang Li, Tao Yang, Zhicheng Xu, Wensi Du, Ling Li, Tanveer Ahmed, Kai You, Zhen Dai, Li Li, Baoming Qin, Yinxiong Li, Liangxue Lai, Dajiang Qin, Junling Chen, Rong Fan, Yongyin Li, Jinlin Hou, Michael Ott, Amar Deep Sharma, Tobias Cantz, Axel Schambach, Karsten Kristiansen, Andrew P Hutchins, Berthold Göttgens, Patrick H Maxwell, Lijian Hui, Xun Xu, Longqi Liu, Ao Chen, Yiwei Lai, Miguel A Esteban
The mechanism by which mammalian liver cell responses are coordinated during tissue homeostasis and perturbation is poorly understood, representing a major obstacle in our understanding of many diseases. This knowledge gap is caused by the difficulty involved with studying multiple cell types in different states and locations, particularly when these are transient. We have combined Stereo-seq (spatiotemporal enhanced resolution omics-sequencing) with single-cell transcriptomic profiling of 473,290 cells to generate a high-definition spatiotemporal atlas of mouse liver homeostasis and regeneration at the whole-lobe scale...
April 16, 2024: Nature Genetics
https://read.qxmd.com/read/38627548/corneal-neuropathic-pain-a-review-to-inform-clinical-practice
#13
REVIEW
Stephanie L Watson, Damien Tuan-Man Le
Corneal neuropathic pain (CNP) is a poorly defined disease entity characterised by an aberrant pain response to normally non-painful stimuli and categorised into having peripheral and central mechanisms, with the former responding to instillation of topical anaesthetic. CNP is a challenging condition to diagnose due to numerous aetiologies, an absence of clinical signs and ancillary tests (in vivo confocal microscopy and esthesiometry), lacking the ability to confirm the diagnosis and having limited availability...
April 16, 2024: Eye
https://read.qxmd.com/read/38627521/direct-conversion-of-methane-to-aromatics-and-hydrogen-via-a-heterogeneous-trimetallic-synergistic-catalyst
#14
JOURNAL ARTICLE
Pengxi Zhu, Wenjuan Bian, Bin Liu, Hao Deng, Lucun Wang, Xiaozhou Huang, Stephanie L Spence, Feng Lin, Chuancheng Duan, Dong Ding, Pei Dong, Hanping Ding
Non-oxidative methane dehydro-aromatization reaction can co-produce hydrogen and benzene effectively on a molybdenum-zeolite based thermochemical catalyst, which is a very promising approach for natural-gas upgrading. However, the low methane conversion and aromatics selectivity and weak durability restrain the realistic application for industry. Here, a mechanism for enhancing catalysis activity on methane activation and carbon-carbon bond coupling has been found to promote conversion and selectivity simultaneously by adding platinum-bismuth alloy cluster to form a trimetallic catalyst on zeolite (Pt-Bi/Mo/ZSM-5)...
April 16, 2024: Nature Communications
https://read.qxmd.com/read/38627502/combined-and-differential-roles-of-add-domains-of-dnmt3a-and-dnmt3l-on-dna-methylation-landscapes-in-mouse-germ-cells
#15
JOURNAL ARTICLE
Naoki Kubo, Ryuji Uehara, Shuhei Uemura, Hiroaki Ohishi, Kenjiro Shirane, Hiroyuki Sasaki
DNA methyltransferase 3A (DNMT3A) and its catalytically inactive cofactor DNA methyltransferase 3-Like (DNMT3L) proteins form functional heterotetramers to deposit DNA methylation in mammalian germ cells. While both proteins have an ATRX-DNMT3-DNMT3L (ADD) domain that recognizes histone H3 tail unmethylated at lysine-4 (H3K4me0), the combined and differential roles of the domains in the two proteins have not been fully defined in vivo. Here we investigate DNA methylation landscapes in female and male germ cells derived from mice with loss-of-function amino acid substitutions in the ADD domains of DNMT3A and/or DNMT3L...
April 16, 2024: Nature Communications
https://read.qxmd.com/read/38627484/nanoparticles-as-an-antidote-for-poisoned-gold-single-atom-catalysts-in-sustainable-propylene-epoxidation
#16
JOURNAL ARTICLE
Qianhong Wang, Keng Sang, Changwei Liu, Zhihua Zhang, Wenyao Chen, Te Ji, Lina Li, Cheng Lian, Gang Qian, Jing Zhang, Xinggui Zhou, Weikang Yuan, Xuezhi Duan
The development of sustainable and anti-poisoning single-atom catalysts (SACs) is essential for advancing their research from laboratory to industry. Here, we present a proof-of-concept study on the poisoning of Au SACs, and the antidote of Au nanoparticles (NPs), with trace addition shown to reinforce and sustain propylene epoxidation. Multiple characterizations, kinetics investigations, and multiscale simulations reveal that Au SACs display remarkable epoxidation activity at a low propylene coverage, but become poisoned at higher coverages...
April 16, 2024: Nature Communications
https://read.qxmd.com/read/38627461/author-correction-hydrogels-with-tunable-mechanical-plasticity-regulate-endothelial-cell-outgrowth-in-vasculogenesis-and-angiogenesis
#17
Zhao Wei, Meng Lei, Yaohui Wang, Yizhou Xie, Xueyong Xie, Dongwei Lan, Yuanbo Jia, Jingyi Liu, Yufei Ma, Bo Cheng, Sharon Gerecht, Feng Xu
No abstract text is available yet for this article.
April 16, 2024: Nature Communications
https://read.qxmd.com/read/38627434/first-public-dataset-to-study-2023-turkish-general-election
#18
JOURNAL ARTICLE
Ali Najafi, Nihat Mugurtay, Yasser Zouzou, Ege Demirci, Serhat Demirkiran, Huseyin Alper Karadeniz, Onur Varol
In the context of Turkiye's most recent parliamentary and presidential elections ("seçim" in Turkish), social media has played an important role in shaping public debate. It is of utmost importance to capture social media trends during the 2023 Turkish elections, since it uncovers a great deal of information of election propaganda, political debates, smear campaigns, and election manipulation by domestic and international actors. We provide a comprehensive dataset for social media researchers to study Turkish elections, develop tools to prevent online manipulation, and gather novel information to inform the public...
April 16, 2024: Scientific Reports
https://read.qxmd.com/read/38627431/author-correction-comprehensive-mutational-scanning-of-egfr-reveals-tki-sensitivities-of-extracellular-domain-mutants
#19
Tikvah K Hayes, Elisa Aquilanti, Nicole S Persky, Xiaoping Yang, Erica E Kim, Lisa Brenan, Amy B Goodale, Douglas Alan, Ted Sharpe, Robert E Shue, Lindsay Westlake, Lior Golomb, Brianna R Silverman, Myshal D Morris, Ty Running Fisher, Eden Beyene, Yvonne Y Li, Andrew D Cherniack, Federica Piccioni, J Kevin Hicks, Andrew S Chi, Daniel P Cahill, Jorg Dietrich, Tracy T Batchelor, David E Root, Cory M Johannessen, Matthew Meyerson
No abstract text is available yet for this article.
April 16, 2024: Nature Communications
https://read.qxmd.com/read/38627430/unexpectedly-uneven-distribution-of-functional-trade-offs-explains-cranial-morphological-diversity-in-carnivores
#20
JOURNAL ARTICLE
Gabriele Sansalone, Stephen Wroe, Geoffrey Coates, Marie R G Attard, Carmelo Fruciano
Functional trade-offs can affect patterns of morphological and ecological evolution as well as the magnitude of morphological changes through evolutionary time. Using morpho-functional landscape modelling on the cranium of 132 carnivore species, we focused on the macroevolutionary effects of the trade-off between bite force and bite velocity. Here, we show that rates of evolution in form (morphology) are decoupled from rates of evolution in function. Further, we found theoretical morphologies optimising for velocity to be more diverse, while a much smaller phenotypic space was occupied by shapes optimising force...
April 16, 2024: Nature Communications
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