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https://read.qxmd.com/read/38537227/presentation-of-wernicke-encephalopathy-in-patient-secondary-to-one-anastomosis-gastric-bypass-case-report-and-literature-review
#1
JOURNAL ARTICLE
Luis F Zorrilla-Núñez, Luis Tamez-Pedroza, Patricio Durán-Moreno, Gerardo E Muñoz-Maldonado
Wernicke encephalopathy, which is caused by a thiamine deficiency, occurs in 0.8-2% of the population. Only 16% present the typical triad of this disease: nystagmus, confusion and ataxia. We present the case of a postoperative patient with a one anastomosis gastric bypass with reoperation undergoing a Roux-en-Y gastric bypass that begins with confusion and nystagmus on her third postoperative day. The diagnosis of Wernicke encephalopathy is made by imaging, and vitamin B1 is administered with total improvement of nystagmus and altered state of consciousness (lethargy, bradypsychia, bradylalia)...
2024: Cirugia y Cirujanos
https://read.qxmd.com/read/38527735/use-of-thiamine-supplementation-in-pregnant-women-diagnosed-with-hyperemesis-gravidarum-and-wernicke-encephalopathy
#2
JOURNAL ARTICLE
Angela Feagan Clark
Hyperemesis gravidarum is the most common condition requiring hospital care for women during the first 20 weeks of pregnancy and may lead to malnutrition, dehydration, and vitamin deficiencies. Depletion of vitamins such as thiamine may result in the development of Wernicke encephalopathy, a severe neurological disorder that can increase the risk for mortality and morbidity for the mother and fetus. A lack of awareness regarding the relationship of hyperemesis gravidarum and Wernicke encephalopathy may result in delayed treatment and disease management...
March 22, 2024: Nursing for Women's Health
https://read.qxmd.com/read/38526684/vitamin-b12-deficiency-induced-megaloblastic-anemia-in-a-pediatric-patient-with-autism-spectrum-disorder-with-a-chronically-unbalanced-diet
#3
JOURNAL ARTICLE
Yuri Sawada, Kenichi Sakamoto, Atsushi Tsukamura, Chihiro Sawai
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by a lack of behavioral flexibility and stereotyped language. Food selectivity is common among children with ASD because of their persnickety nature. A prolonged unbalanced diet results in an increased risk of several diseases, such as iron deficiency anemia, scurvy, rickets, dry eye, and Wernicke encephalopathy. However, no cases of megaloblastic anemia have been reported to date. We report the case of an 11-year-old boy with ASD who developed megaloblastic anemia due to vitamin B12 deficiency...
March 25, 2024: International Journal of Hematology
https://read.qxmd.com/read/38520815/vitamin-deficiencies-in-children-lessons-from-clinical-and-neuroimaging-findings
#4
JOURNAL ARTICLE
Gabrielle Dupuy, Charles-Joris Roux, Rémi Barrois, Apolline Imbard, Clément Pontoizeau, Marie Thérèse Dangles, Mélodie Aubart, Jean-Baptiste Arnoux, Diane Margoses, Anaïs Brassier, Clothilde Marbach, Claire-Marine Bérat, Eugénie Sarda, Cyril Gitiaux, Pascale de Lonlay, Nathalie Boddaert, Manuel Schiff, Isabelle Desguerre
BACKGROUND AND AIMS: Water-soluble vitamins play an essential coenzyme role in the nervous system. Acquired vitamin deficiencies are easily treatable, however, without treatment, they can lead to irreversible complications. This study aimed to provide clinical, laboratory parameters and neuroimaging data on vitamin deficiencies in an attempt to facilitate early diagnosis and prompt supplementation. METHODS: From July 1998 to July 2023, patients at Necker-Enfants-Malades Hospital presenting with acute neurological symptoms attributed to acquired vitamin deficiency were included...
February 26, 2024: European Journal of Paediatric Neurology: EJPN
https://read.qxmd.com/read/38469004/rehabilitation-strategies-for-wernicke-korsakoff-syndrome-physiotherapy-interventions-and-management-approaches
#5
Ghanishtha C Burile, Neha Arya, Nikita H Seth, Tejaswini Fating
Korsakoff syndrome and Wernicke's encephalopathy (WE) show neurological and cognitive deficits. Wernicke-Korsakoff syndrome (WKS) is a compound neurological condition. The cause of this neurological condition could be the consumption of alcohol regularly for a chronic duration. A tailored rehabilitation protocol that focuses on cognitive and physical deficiencies was implemented along with thiamine supplementation for managing a case of a 49-year-old male patient who had a history of high alcohol consumption and was exhibiting typical signs of WKS...
February 2024: Curēus
https://read.qxmd.com/read/38463520/letter-to-the-editor-total-parenteral-nutrition-induced-wernicke-s-encephalopathy-after-oncologic-gastrointestinal-surgery
#6
JOURNAL ARTICLE
Oguzhan Koca, Zeynep Hande Turna
No abstract text is available yet for this article.
2024: Open Medicine (Warsaw, Poland)
https://read.qxmd.com/read/38449490/seizures-in-the-third-trimester-of-pregnancy-a-rare-case-of-wernicke-s-encephalopathy-mimicking-eclampsia
#7
Badra Bannour, Maroi Baazaoui, Maroi Bannour, Imen Bannour, Hiba Abdellaoui, Khaled Ben Jazia
Unless otherwise demonstrated, seizures during pregnancy that happen after 20 weeks of gestation are typically caused by eclampsia. In our clinical case we report the diagnostic challenge of Wernicke's encephalopathy occurring at 34 weeks and mimicking an eclamptic attack. This is about a 30-year-old female patient who suffers from hyperemesis gravidarum during her pregnancy. she has no known history of epilepsy .The patient was brought to the emergency room by medical transport at 34 weeks of gestation due to a seizure at home...
May 2024: Radiology Case Reports
https://read.qxmd.com/read/38449424/altered-mental-status-and-cardiac-failure-due-to-thiamine-deficiency-in-an-overweight-teen
#8
JOURNAL ARTICLE
Brittany M Slagle, Trevor Meece, Claire Foster, Andrew Campbell, Lauren Tong, Paul Drake
We describe an overweight but otherwise previously healthy 17-year-old female who presented with altered mental status and rapidly progressive weakness. She was ultimately diagnosed with Wernicke encephalopathy and wet beriberi resulting from severe thiamine deficiency. She required admission to the pediatric ICU because of hypoventilation with progressive weakness and worsening encephalopathy and was found to have impaired cardiac function as assessed by echocardiography. Her heart function and encephalopathy improved on initiation of thiamine repletion...
March 7, 2024: Pediatrics
https://read.qxmd.com/read/38417935/nystagmus-in-a-child-with-nephrotic-syndrome
#9
JOURNAL ARTICLE
Hamsa Vasantha Shekar Reddy, Divya S Nagabushana, Deepthi Kattamanchi, Ahish Dakappa
We report a child with steroid-dependent nephrotic syndrome presenting with excessive irritability, double vision and inability to walk for 5 days. On examination, the child was irritable with Glasgow coma sccale (GCS of 12/15, had bilateral convergent squint (R>L), vertical nystagmus, ataxia without any focal neurological deficits and normal fundus. MRI brain with venogram showed bilateral symmetric FLAIR hyperintensity in the medial thalamus and periaqueductal grey matter showing diffuse restriction with normal venogram...
February 27, 2024: BMJ Case Reports
https://read.qxmd.com/read/38417618/carl-wernicke-of-wernicke-s-area-a-historical-review
#10
REVIEW
Abdullah Ahmad, Nitin Jagdhane, Karin Ademmer, Kishor Choudhari
Wernicke's area, also known as Brodmann area 22, is located in the posterior segment of the superior temporal gyrus in the dominant hemisphere. Carl Wernicke, a German neurologist, described this area in 1874. The life story of Carl Wernicke, a 19th century medical genius, remains an inspiration for all neuroscientists even a hundred years later. The authors outline Wernicke's life story and academic achievements in the fields of neurosurgery, neurology, and psychiatry. We explore his remarkable ability to turn his many setbacks into steps forward, his controversial foray into psychiatry, and his wide-ranging set of contributions including: his work on external ventricular drainage for hydrocephalus; encephalopathy; his description of the eponymous Wernicke's area; and his field-defining work on aphasia...
February 26, 2024: World Neurosurgery
https://read.qxmd.com/read/38415422/-hyperemesis-gravidarum-leading-to-gayet-wernicke-encephalopathy
#11
JOURNAL ARTICLE
Amine Bentahar, Taoufik Boubga, Habib Bellamlih, Khalil Chafi, Monsif Salek, Soufiane Belabbes, Brahim Zinoun, Taoufik Africha
No abstract text is available yet for this article.
February 2024: La Revue du Praticien
https://read.qxmd.com/read/38392959/the-effects-of-intensive-rehabilitation-combined-with-thiamine-treatment-on-cognitive-recovery-in-a-case-of-non-alcoholic-wernicke-korsakoff-syndrome
#12
Cinzia Palmirotta, Gilda Turi, Serena Tagliente, Michele Pansini, Stefania De Trane, Gianvito Lagravinese
Wernicke-Korsakoff Syndrome (WKS) is a severe neurological disorder resulting from thiamine deficiency, commonly associated with alcohol consumption but also stemming from dietary imbalances or other clinical conditions. Cognitive deficits, affecting memory and executive functions, pose a serious concern, with partial recovery often not complete. A 28-year-old woman underwent surgery for acute necrotizing hemorrhagic pancreatitis, leading to admission for post-acute intensive treatment due to prolonged bed rest syndrome...
February 14, 2024: Neurology International
https://read.qxmd.com/read/38384693/wernicke-encephalopathy-with-atypical-imaging-findings-in-a-depressed-patient-a-case-report
#13
Hiroyuki Tokue, Rei Ishikawa, Kiyohiro Oshima, Yusuke Sawada, Yuto Aramaki, Kei Kawano, Takumi Nihei, Kouta Isogai, Kohei Kawahara, Takayuki Yokota, Hiroyuki Yasui, Miho Ikeya, Tamaki Okabe, Azusa Tokue, Yoshito Tsushima
This case report highlights the rare occurrence of Wernicke encephalopathy caused by malnutrition in a depressed patient with atypical imaging findings. A 60-year-old female with depression developed a disturbance of consciousness owing to Wernicke encephalopathy. Magnetic resonance imaging showed abnormal signals in the thalamus and mammillary bodies around the third ventricle, cerebral aqueduct, and fourth ventricle. Abnormal signals were also present in the cerebral cortex around the central sulcus, and an intracranial hemorrhage from the thalamus was observed...
May 2024: Radiology Case Reports
https://read.qxmd.com/read/38375122/dehydrogenase-dld-deficiency-in-an-iranian-patient-with-recurrent-intractable-vomiting-successful-treatment-with-thiamine-supplementation
#14
Toktam Moosavian, Ghazaleh Jamalipour Soufi, Sharareh Kamfar
Dihydrolipoamide dehydrogenase (DLD) deficiency is a rare disease of genetic origin due to the malfunctioning of a shared subunit of three mitochondrial multi-enzyme complexes. Phenotypes of this disease are a set of clinical manifestations ranging from neonatal disorders to myopathy or recurrent episodes of liver failures, and vomiting for which no adequate or definitive treatment is currently available. This study described a case involving a 16-year-old boy who had experienced recurrent vomiting of unknown cause from age two...
2024: Iranian Journal of Child Neurology
https://read.qxmd.com/read/38372521/uncommon-bilateral-optic-neuropathy-in-wernicke-s-encephalopathy-complicating-gravidarum-hyperemesis
#15
JOURNAL ARTICLE
Mejda Bouladi, Houda Lajmi, Amal Ben Othmen, Lamia El Fekih
Wernicke encephalopathy (WE) is a rare neurological disorder that results from vitamin B1 (Thiamin) deficiency, classically characterized by the triad of ophtalmoplagia, altered consciousness, and ataxia. WE is often associated with alcoholism, malnutrition, or gastrointestinal diseases with malabsorption. The association of «gravidarum hyperemesis» and WE seems to be underestimated. We report a 24-year-old pregnant woman with hyperemesis gravidarum, who presented with decreased visual acuity of both eyes...
May 5, 2023: La Tunisie Médicale
https://read.qxmd.com/read/38347991/silent-echoes-a-case-report-of-wernicke-encephalopathy-s-unheard-voice
#16
Stefan Gafoor, Raheem Robertson
Wernicke encephalopathy (WE) is an acute neuropsychiatric emergency that is caused by a deficiency in vitamin B1 (thiamine). This condition is most commonly seen in patients with alcohol use disorder; however, patients with other disorders of severe malnourishment are also at increased risk. In severe cases, this disease may be followed by Korsakoff's psychosis and even death.  We present a case of a 64-year-old African American female with a history of alcohol use disorder who presented to the emergency department on account of an acute confusional state...
January 2024: Curēus
https://read.qxmd.com/read/38344547/nystagmus-and-abducens-nerve-palsy-as-an-early-presentation-of-non-alcoholic-wernicke-encephalopathy
#17
Siti Hajar Darussalam, Muhammad Mohd Isa, Rafidah Md Saleh, Adzleen Mohmood, Amirah Mohammad Razali
Wernicke encephalopathy (WE) is a rare but life-threatening syndrome that is commonly associated with chronic alcoholism. It has also been found to be associated with malnutrition, prolonged parenteral nutrition, hemodialysis, hyperemesis gravidarum, gastroplasty, and AIDS. It usually presents as a clinical triad of confusion, ophthalmoplegia, and gait ataxia. Nystagmus is usually the most common and earliest ophthalmologic sign. We report a case of non-alcoholic WE in a patient who had prior bariatric surgery and was treated for malnutrition and sepsis, with nystagmus being the initial presentation...
January 2024: Curēus
https://read.qxmd.com/read/38337411/wernicke-syndrome-case-report-and-literature-review-of-contributing-factors-can-malpractice-dynamics-be-identified
#18
REVIEW
Donatella Mangione, Alessandra Vassiliadis, Giuseppe Gullo, Cetty Gullo, Gaspare Cucinella, Renato Venezia, Simona Zaami
Wernicke Encephalopathy (WE) is a neurological acute syndrome related to vitamin B1 deficiency and is relatively common in patients with chronic alcoholism. In the case of Hyperemesis Gravidarum, thiamine body stores become unable to meet the increased demand, resulting in acute deficiency. WE is associated with typical clinical and radiological findings. Treatment pathways rely on thiamine replacement. The case herein reported is centered around a 33-year-old diabetic patient at 12 weeks of gestation, with WE due to hyperemesis gravidarum...
January 26, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38306946/diagnosis-and-treatment-of-wernicke-s-encephalopathy-a-systematic-literature-review
#19
REVIEW
Ashley Cantu-Weinstein, Rachel Branning, Maria Alamir, Jeremy Weleff, Molly Do, Neil Nero, Akhil Anand
BACKGROUND: Wernicke's encephalopathy (WE) is a serious neurological disorder that is underdiagnosed. Despite limited clinical guidelines, the standard use of intravenous (IV) thiamine is underutilized and remains an area of research deserving much attention. OBJECTIVES: We conducted a systematic review using Medline, Embase, and CENTRAL databases to identify and summarize the literature on IV thiamine treatment in WE. Human studies with WE patients who received ≥100 mg of thiamine IV met inclusion criteria...
2024: General Hospital Psychiatry
https://read.qxmd.com/read/38296505/atypical-wernicke-s-encephalopathy-without-mental-status-changes-following-bariatric-surgery-in-an-adolescent-patient
#20
JOURNAL ARTICLE
Asra Akbar, Jason Lowther, Sean Creeden, William Frese
Morbid obesity is a systemic disease which can result in chronic complications, including hypertension, diabetes mellitus, depression, osteoarthritis and low self-esteem in the adolescent population.Bariatric surgery can be indicated to treat more severe forms of obesity, but these procedures are not without long-term risks. Therefore, adequate preoperative and postoperative care, which includes preoperative psychosocial evaluation for compliance, ongoing nutrition counselling and vitamin and micronutrient supplementation, is required for all patients, especially adolescent patients, who generally may not comply with medical therapies and/or be able to developmentally fully appreciate or comprehend the health consequences of their behaviours, prior to as well as after bariatric surgery to prevent complications...
January 31, 2024: BMJ Case Reports
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