Chao Li, Yuxin Xiong, Zhe Fu, Yuxin Ji, Jiayi Yan, Yan Kong, Ying Peng, Zeqiong Ru, Yubing Huang, Yilin Li, Ying Yang, Li He, Jing Tang, Ying Wang, Xinwang Yang
BACKGROUND: Chronic nonhealing wounds remain a considerable challenge in clinical treatment due to excessive inflammation and impeded reepithelialization and angiogenesis. Therefore, the discovery of novel prohealing agents for chronic skin wounds are urgent and important. Amphibian-derived prohealing peptides, especially immunomodulatory peptides, provide a promising strategy for the treatment of chronic skin trauma. However, the mechanism of immunomodulatory peptides accelerating the skin wound healing remains poorly understood...
February 5, 2024: Cellular & Molecular Biology Letters