Juan Wang, Danqing Wang, Mingquan Huang, Baoguo Sun, Fazheng Ren, Jihong Wu, Jinglin Zhang, Hehe Li, Xiaotao Sun
Sotolone, a chiral compound, plays an important role in the food industry. Herein, ( R )-/( S )-sotolone were separated to determine their odor characteristics and thresholds in air ( R -form: smoky, burned, herb, and green aroma, 0.0514 μg/m3 ; S -form: sweet, milk, acid, and nutty aroma, 0.0048 μg/m3 ). OR8D1 responses to ( R )-/( S )-sotolone were detected in a HEK293 cell-based luminescence assay. ( S )-Sotolone was a more potent agonist than ( R )-sotolone (EC50 values of 84.98 ± 1.05 and 167...
February 22, 2024: Journal of Agricultural and Food Chemistry