Michaël J Girard, Satish Panda, Tin Aung Tun, Elisabeth A Wibroe, Raymond P Najjar, Tin Aung, Alexandre H Thiéry, Steffen Hamann, Clare Fraser, Dan Milea
BACKGROUND AND OBJECTIVES: The distinction of papilledema from other optic nerve head (ONH) lesions mimicking papilledema, such as optic disc drusen (ODD), can be difficult in clinical practice. We aimed: (1) To develop a deep learning algorithm to automatically identify major structures of the optic nerve head (ONH) in three dimensional (3D) optical coherence tomography (OCT) scans; (2) To exploit such information to robustly differentiate among ODD, papilledema, and healthy ONHs. METHODS: This was a cross-sectional comparative study of patients from three sites (Singapore, Denmark, Australia) with confirmed ODD, papilledema due to raised intracranial pressure, and healthy controls...
September 29, 2022: Neurology