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G Siebenbürger, B Grabein, T Schenck, C Kammerlander, W Böcker, C Zeckey
BACKGROUND: Multi-drug-resistant bacteria (e.g. Carbapenem-resistant Acinetobacter baumannii, extended-spectrum betalactamase or carbapenemase-producing enterobacteriaceae) are emerging in early-onset infections. So far, there is no report describing the eradication of these bacteria in a osseous infection of an open proximal tibial fracture in combination with the hexapod technology to address both osseous consolidation and closed drop foot correction. CASE PRESENTATION: After sustaining a proximal tibial fracture (Gustilo 3B), a 41-year-old man was primarily treated with open reduction and internal fixation by a locking plate and split-thickness skin graft in the home country...
January 19, 2019: European Journal of Medical Research
Sonya Yu, Deanna Morrow, Vaughan Moutrie, David Lurie
In this prospective, exploratory study, we evaluated the positioning accuracy in a group of 15 dogs undergoing fractionated stereotactic radiotherapy for tumors affecting the head, using a modified human maxillary fixation device (Elekta Fraxion™ system). Positioning was assessed using on-board volumetric imaging, with a six-degrees-of-freedom image registration technique. Prior to treatment delivery, CBCT images were obtained and patient alignment was corrected, in both translational and rotational planes, using a six-degrees-of-freedom robotic patient positioning system (HexaPOD Evo RT System)...
January 18, 2019: Veterinary Radiology & Ultrasound
Chia-Jui Hu, Tso-Kang Wang, Chun-Kai Huang, Pei-Chun Lin
We report on the development and analysis of a new torque-actuated dissipative spring loaded inverted pendulum model with rolling contact (TDR-SLIP), which is a successor to the previously developed spring loaded inverted pendulum model with rolling contact (R-SLIP) model. The stability properties of the models were analyzed numerically via steps-to-fall analysis and return map analysis, wherein the dimensionless parameters are varied to analyze their effects on the dynamic performance of the model, including torque, damping constant, touchdown angle, touchdown speed, and landing angle...
January 7, 2019: Bioinspiration & Biomimetics
Na Wang, Wenjie Ma, Yunchen Du, Ziqiu Ren, Binhua Han, Leijiang Zhang, Bojing Sun, Ping Xu, Xijiang Han
The morphology-dependent property of crystal materials has aroused extensive attentions and raised high requirements for subtly tailoring the morphology of micro-/nanocrystals. Herein, we develop an in-situ etching method for preparation of Prussian blue (PB) microcrystals with morphology evolution by progressively increasing the concentration of chloroplatinic acid in the reaction system. These PB microcrystals with controllable morphologies are employed as photo-Fenton reagents to degrade organic pollutants...
December 17, 2018: ACS Applied Materials & Interfaces
Simone Riganti, Luigi A Nasto, Salvatore Mannino, Giorgio Marrè Brunenghi, Silvio Boero
The aim of this study was to compare clinical and radiographical results for treatment of lower limb multiaxial deformities±limb length discrepancy (LLD) of at least 2 cm with the Truelok hexapod fixator system (TL-HEX). All consecutive cases of lower limb multiaxial deformities were included. Patients were divided in two groups: group 1, lower limb angular deformity+LLD less than 2 cm, and group 2, lower limb angular deformity+LLD of at least 2 cm. Only patients with age younger than or equal to 20 years and follow-up of 6 months after removal of the external fixator were included...
December 8, 2018: Journal of Pediatric Orthopedics. Part B
Toru Miura
Phenotypic plasticity and polyphenism, in which phenotypes can be changed depending on environmental conditions, are common in insects. Several studies focusing on physiological, developmental, and molecular processes underlying the plastic responses have revealed that similar endocrine mechanisms using juvenile hormone (JH) are used to coordinate the flexible developmental processes. This review discusses accumulated knowledge on the caste polyphenism in social insects (especially termites), the wing and the reproductive polyphenisms in aphids, and the nutritional polyphenism and sexual dimorphism in stag beetles...
November 23, 2018: Development, Growth & Differentiation
Zihao Ou, Xiaohui Song, Wen Huang, Xing Jiang, Subing Qu, Qingyi Wang, Paul V Braun, Jeffrey S Moore, Xiuling Li, Qian Chen
Recent studies on the effect of particle shapes have led to extensive applications of anisotropic colloids as complex materials building blocks. Although much research has been devoted to colloids of convex polyhedral shapes, branched colloids remain largely underexplored because of limited synthesis strategies. Here we achieved the preparation of metal-organic framework (MOF) colloids in a hexapod shape, not directly from growth but from postsynthesis etching of truncated rhombic dodecahedron (TRD) parent particles...
November 16, 2018: ACS Applied Materials & Interfaces
Xing Song, Shuiping Luo, Xiaokun Fan, Min Tang, Xixia Zhao, Wen Chen, Qi Yang, Zewei Quan
Well-defined PtNi nanocrystals represent one of the most efficient electrocatalysts to boost the oxygen reduction reaction (ORR), especially in the shape of octahedrons, nanoframes, and nanowires. However, the synthesis of complex PtNi nanostructure is still a great challenge. Herein, we report a new class of PtNi hexapods with high activity and stability toward ORR. The hexapods are prepared by selective capping and simultaneous corrosion. By controlling the oxidative etching, PtNi polyhedrons and nanoparticles are obtained, respectively...
2018: Frontiers in Chemistry
Daniel L Saenz, Ying Li, Karl Rasmussen, Sotirios Stathakis, Evangelos Pappas, Niko Papanikolaou
BACKGROUND AND PURPOSE: With the increasingly prominent role of stereotactic radiosurgery in radiation therapy, there is a clinical need for robust, efficient, and accurate solutions for targeting multiple sites with one patient setup. The end-to-end accuracy of high definition dynamic radiosurgery with Elekta treatment planning and delivery systems was investigated in this study. MATERIALS AND METHODS: A patient-derived CT scan was used to create a radiosurgery plan to seven targets in the brain...
October 2018: Physica Medica: PM
Simone Riganti, Valentino Coppa, Luigi Aurelio Nasto, Mauro Di Stadio, Maria Grazia Calevo, Antonio Pompilio Gigante, Silvio Boero
BACKGROUND: Treatment of complex foot deformities in growing children and young adult patients is challenging. The traditional approach consists of extensive soft tissues releases, osteotomies and/or arthrodesis. More recently, distraction osteogenesis has been proposed as an alternative strategy. The aim of this study was to describe our treatment strategy and report clinical outcomes of the patients affected from complex foot deformities treated by distraction osteogenesis and hexapod external fixator...
July 9, 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Rita EusÉbio, Alberto Sendra, Henrik Enghoff, Ana Sofia P S Reboleira
A catalogue of type specimens of basal hexapods (Collembola, Protura, Diplura, Archaeognatha, Zygentoma) in the collection of the Natural History Museum of Denmark, University of Copenhagen is presented. The NHMD collection harbours type material of 175 species, and it is composed of 132 holotypes, 4 neotypes, 3 syntypes, 32 lectotypes, and 39 paratypes. For Diplura one neotype is newly designated. The order Protura is represented by 5 families, Collembola by 7 families, Diplura by 6 families, Archaeognatha by 1 family and Zygentoma by 2 families...
August 8, 2018: Zootaxa
Zhuoqiang Jia, Jae-Hyun Kim, Gi-Ra Yi, Stephanie S Lee
Aspherical cubic hematite colloids with cylindrical arms protruding from each face, referred to as "hexapods", were assembled via negative dielectrophoresis and then manipulated using an applied magnetic field. Upon application of an ac electric field, the hexapods aligned in close-packed linear chains parallel to the field direction. The chains then aggregated to the center of the device, with adjacent chains separated by distances approximately equal to twice the arm length. The resulting open packing structure exhibited cmm plane group symmetry due to the obstruction of arms, with a high density of incorporated defects...
October 5, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
Mitchell Bernstein, Austin Fragomen, S Robert Rozbruch
Background: Massive bone defects (>8 cm) will not unite without an additional intervention. They require a predictable, durable, and efficient method to regrow bone. The Ilizarov method of tension stress, or distraction osteogenesis, first involves a low-energy osteotomy1-5 . The bone segments are then pulled apart, most often using an external device at a specific rate and rhythm (distraction phase), after which the newly formed bone (the regenerate) requires time for consolidation...
March 28, 2018: JBJS Essential Surgical Techniques
Guido A LaPorta, Alison D'Andelet
Charcot neuroarthropathy is a disabling pathology in the foot and ankle. Midfoot Charcot is most common and results in progressive deformity. We describe a 2-step approach to surgical reconstruction, referred to as the lengthen, alignment, and beam technique. There is an initial surgery involving acute equinus correction through Achilles tendon lengthening and gradual correction with hexapod external fixation to align the deformity, followed by minimally invasive medial and lateral column beaming. This surgical protocol allows for adequate reduction of deformity...
October 2018: Clinics in Podiatric Medicine and Surgery
Alexander M Cherkashin, Mikhail L Samchukov, Franz Birkholts
To provide standardized nomenclature for various hexapod frame configurations for foot and ankle deformity correction, a unique classification of the hexapod external fixators was proposed. This classification is based on number of correction levels, secured anatomic blocks, and direction of the strut attachment. It allows the combination of all different foot and ankle frame assemblies into a few standard hexapod configurations, irrespective of which external fixator is used.
October 2018: Clinics in Podiatric Medicine and Surgery
Carlos A Peña-Solórzano, Matthew R Dimmock, David W Albrecht, David M Paganin, Richard B Bassed, Mitzi Klein, Peter C Harris
External fixation is a common tool in the treatment of complex fractures, correction of limb deformity, and salvage arthrodesis. These devices typically incorporate radio-opaque metal rods/struts connected at varying distances and orientations between rings. Whilst the predominant imaging modality is plain film radiology, computed tomography (CT) may be performed in order for the surgeon to make a more confident clinical decision (e.g. timing of frame removal, assessment of degree of arthrodesis). We used a fractured sheep leg to systematically assess CT imaging performance with a Discovery CT750 HD CT scanner (GE Healthcare) to show how rod coupling in both traditional Ilizarov and hexapod frames distorts images...
September 15, 2018: Strategies in Trauma and Limb Reconstruction
Pablo S Corona, Matías Vicente, Kevin Tetsworth, Vaida Glatt
BACKGROUND: Preoperative planning for circular external fixators is considered vital towards achieving the best results for complex post-traumatic tibial deformities, and patient-specific 3D printed (3DP) models were used here as a planning aid. The main goal was to investigate the fidelity of the preoperative planning process, by assessing the potential to reduce operative time and determining the need to adjust pre-constructed frames intra-operatively. PATIENTS AND METHODS: Nine patients (10 limbs) underwent treatment for post-traumatic tibial complications using circular external fixation...
September 2018: Injury
Hendrik Langeloh, Hannah Wasser, Nicole Richter, Gerd Bicker, Michael Stern
Background: The neuromuscular junction is the chemical synapse where motor neurons communicate with skeletal muscle fibers. Whereas vertebrates and many invertebrates use acetylcholine as transmitter at the neuromuscular junction, in those arthropods examined up to now, glutamate and GABA are used instead. With respect to taxon sampling in a phylogenetic context, there is, however, only a limited amount of data available, focusing mainly on crustaceans and hexapods, and neglecting other, arthropod groups...
2018: Frontiers in Zoology
Céline Klein, Yassine Bulaid, François Deroussen, Marie-Christine Plancq, Camille Printemps, Richard Gouron
Congenital knee dislocation (CDK) is a rare condition, and its treatment is subject to debate. Here, we report on a new treatment for CDK (using a hexapod-type external fixator, HEF) in a three-year-old child with Larsen syndrome and grade III anterior dislocations of both knees. The left knee was treated with serial splints, whereas an HEF was used to treat an irreducible dislocation of the right knee. Two HEF aluminium rings were applied surgically. The procedure involved a distraction of the knee, then tibial posterior translation, and lastly progressive flexion...
October 2018: Knee
Lucas Freitas, Beatriz Mello, Carlos G Schrago
The multispecies coalescent (MSC) has been increasingly used in phylogenomic analyses due to the accommodation of gene tree topological heterogeneity by taking into account population-level processes, such as incomplete lineage sorting. In this sense, the phylogeny of insect species, which are characterized by their large effective population sizes, is suitable for a coalescent-based analysis. Furthermore, studies so far recovered short internal branches at early divergences of the insect tree of life, indicating fast evolutionary radiations that increase the probability of incomplete lineage sorting in deep time...
November 2018: Journal of Evolutionary Biology
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