keyword
https://read.qxmd.com/read/38524644/complete-reduction-surgery-of-a-huge-recurrent-adult-granulosa-cell-tumor-after-neoadjuvant-chemotherapy
#21
JOURNAL ARTICLE
Hiroha Tokui, Hideaki Yahata, Yasuhiro Okabe, Naomi Magarifuchi, Shoji Maenohara, Kazuhisa Hachisuga, Hiroshi Tomonobe, Keisuke Kodama, Hiroshi Yagi, Masafumi Yasunaga, Ichiro Onoyama, Kazuo Asanoma, Yoshinao Oda, Masafumi Nakamura, Kiyoko Kato
Adult granulosa cell tumors are rare, accounting for only 3-5% of all ovarian tumors. Adult granulosa cell tumors have late recurrences, for which complete resection is an effective option. We report a patient who underwent complete resection of a huge recurrent adult granulosa cell tumor after neoadjuvant chemotherapy. A 72-year-old woman underwent primary surgery for an adult granulosa cell tumor 19 years earlier. A huge recurrent tumor, 11 × 10 cm in size, was noted to elevate the hepatic hilum, inferior vena cava, and right renal vein...
April 2024: International cancer conference journal
https://read.qxmd.com/read/38524396/immune-checkpoint-inhibitor-associated-systemic-sclerosis-in-the-treatment-of-a-small-cell-lung-cancer-patient-with-durvalumab-a-case-report
#22
De-Hu Li, Xian-Zhi Xiong
As one of the key cancer treatment measures, immune-checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of various cancers, including malignancies previously thought to be untreatable. Immune checkpoint inhibitors work by targeting the dysfunctional immune system, to enhance cancer-cell killing by CD8-positive T cells. Despite the beneficial effects of ICIs, these treatments are also linked to a novel class of side effects, termed immune-related adverse events (irAEs). Immune-related adverse events can affect multiple organ systems, such as endocrine, neurological, gastroenteric, dermatologic, ocular, hepatic, renal, and rheumatic ones...
2024: Clinical, Cosmetic and Investigational Dermatology
https://read.qxmd.com/read/38521948/anastomosis-selection-in-liver-transplantation-for-recipients-with-unusable-recipient-hepatic-arteries-a-bayesian-network-meta-analysis
#23
Warsinggih, Citra Aryanti, Julianus Aboyaman Uwuratuw, Erwin Syarifuddin, Ronald Erasio Lusikooy, Muhammad Faruk
BACKGROUND: The anastomosis of donor and recipient hepatic arteries is standard in liver transplantations. For transplant recipients with unusable hepatic arteries, appropriate artery selection should be conducted using evidence-based considerations; therefore, this network meta-analysis (NMA) aimed to analyze the most suitable alternative recipient artery for anastomosis during liver transplantations. METHODS: Comprehensive searches of the Scopus, Cochrane Library, and MEDLINE databases were conducted to analyze observational studies containing non-standard anastomoses in liver transplantations that used the splenic artery, aorta, celiac, or branches of the gastric artery...
March 23, 2024: BMC Surgery
https://read.qxmd.com/read/38521190/hepatic-adenoma-evolution-of-a-more-individualized-treatment-approach
#24
REVIEW
Hassan Aziz, Patrick W Underwood, Matthew D Gosse, Shadi Afyouni, Ihab Kamel, Timothy M Pawlik
BACKGROUND: Hepatic adenomas (HAs) are benign, solid liver lesions, which carry a risk of hemorrhage and malignant transformation. In this review article, we highlight advances in the diagnosis and management of HAs. METHODS: A comprehensive review was performed utilizing MEDLINE/PubMed and Web of Science databases with a search period ending September 30, 2023. Using PubMed, the terms "hepatocellular," "hepatic," and "adenoma" were searched. RESULTS: HA has been classified into at least eight subtypes based on molecular pathology, each exhibiting unique histopathological features, clinical considerations, and risk of malignant transformation...
March 16, 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38520580/predicting-the-risk-of-morbidity-by-glim-based-nutritional-assessment-and-body-composition-analysis-in-oncologic-abdominal-surgery-in-the-context-of-enhanced-recovery-programs-the-phase-angle-value-in-abdominal-surgery-phavas-study
#25
JOURNAL ARTICLE
Marta Sandini, Luca Gianotti, Salvatore Paiella, Davide P Bernasconi, Linda Roccamatisi, Simone Famularo, Matteo Donadon, Gabriele Di Lucca, Marco Cereda, Edoardo Baccalini, Giovanni Capretti, Gennaro Nappo, Amanda Casirati, Marco Braga, Alessandro Zerbi, Guido Torzilli, Claudio Bassi, Roberto Salvia, Emanuele Cereda, Riccardo Caccialanza
BACKGROUND: Preoperative nutritional status and body structure affect short-term prognosis in patients undergoing major oncologic surgery. Bioimpedance vectorial analysis (BIVA) is a reliable tool to assess body composition. Low BIVA-derived phase angle (PA) indicates a decline of cell membrane integrity and function. The aim was to study the association between perioperative PA variations and postoperative morbidity following major oncologic upper-GI surgery. PATIENTS AND METHODS: Between 2019 and 2022 we prospectively performed BIVA in patients undergoing surgical resection for pancreatic, hepatic, and gastric malignancies on the day before surgery and on postoperative day (POD) 1...
March 23, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38520294/risk-prediction-and-analysis-of-gallbladder-polyps-with-deep-neural-network
#26
JOURNAL ARTICLE
Kerong Yuan, Xiaofeng Zhang, Qian Yang, Xuesong Deng, Zhe Deng, Xiangyun Liao, Weixin Si
The aim of this study is to analyze the risk factors associated with the development of adenomatous and malignant polyps in the gallbladder. Adenomatous polyps of the gallbladder are considered precancerous and have a high likelihood of progressing into malignancy. Preoperatively, distinguishing between benign gallbladder polyps, adenomatous polyps, and malignant polyps is challenging. Therefore, the objective is to develop a neural network model that utilizes these risk factors to accurately predict the nature of polyps...
December 2024: Computer Assisted Surgery (Abingdon, England)
https://read.qxmd.com/read/38520291/modified-graham-patch-repair-of-small-bowel-anastomotic-leak
#27
JOURNAL ARTICLE
Ashley Alden, Robert D Bennett
The modified Graham patch repair is a well-established technique for management of perforating foregut injuries, often learned by surgeons during general surgery training. There is, however, little to no data regarding the utilization of this technique for perforation of the distal midgut or in the re-operative field. We present two cases of midgut anastomotic complications successfully managed with modified graham patch repair at our institution. The first case is a 79-year-old female who underwent an emergent right hemicolectomy at an outside institution for management of an iatrogenic perforation during endoscopic polypectomy...
March 23, 2024: American Surgeon
https://read.qxmd.com/read/38519782/icg-enhanced-compression-anatomical-segment-7-segmentectomy-in-laparoscopic-and-robotic-approach
#28
JOURNAL ARTICLE
Fabio Procopio, Giulia Mauri, Flavio Milana, Bruno Braciforte, Jacopo Galvanin, Guido Costa, Camilla Pasetti, Guido Torzilli
BACKGROUND: Minimally invasive anatomical resection (AR) for posterosuperior lesions is technically challenging.1,2 The Glissonean approach or puncture technique is generally selected.3,4 The tumor-feeding portal pedicle compression AR (C-AR) is an established procedure in open surgery.5 This technique has benefited from the association with indocyanine green (ICG) fluorescence, used to enhance the anatomical area to be resected.6 Recently, C-AR via the minimal access approach has been reported...
March 22, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38519637/correlation-between-magnetic-resonance-imaging-proton-density-fat-fraction-mri-pdff-and-liver-biopsy-to-assess-hepatic-steatosis-in-obesity
#29
JOURNAL ARTICLE
Pornphan Wibulpolprasert, Benya Subpinyo, Supphamat Chirnaksorn, Prapimporn Chattranukulchai Shantavasinkul, Supanee Putadechakum, Sith Phongkitkarun, Chanika Sritara, Napat Angkathunyakul, Preeda Sumritpradit
Obesity is highly associated with Non-alcoholic fatty liver disease (NAFLD) and increased risk of liver cirrhosis and liver cancer-related death. We determined the diagnostic performance of the complex-based chemical shift technique MRI-PDFF for quantifying liver fat and its correlation with histopathologic findings in an obese population within 24 h before bariatric surgery. This was a prospective, cross-sectional, Institutional Review Board-approved study of PDFF-MRI of the liver and MRI-DIXON image volume before bariatric surgery...
March 22, 2024: Scientific Reports
https://read.qxmd.com/read/38519407/clinician-overconfidence-in-visual-estimation-of-the-posthepatectomy-liver-remnant-volume-a-proximal-source-of-liver-failure-after-major-hepatic-resection
#30
JOURNAL ARTICLE
Camelia Forton, Victor Sandoval, Issac R Schwantes, Ranish K Patel, Kenneth J Kolbeck, Elizabeth N Dewey, Elena K Korngold, Skye C Mayo
BACKGROUND: Post-hepatectomy liver failure is a source of morbidity and mortality after major hepatectomy and is related to the volume of the future liver remnant. The accuracy of a clinician's ability to visually estimate the future liver remnant without formal computed tomography liver volumetry is unknown. METHODS: Twenty physicians in diagnostic radiology, interventional radiology, and hepatopancreatobiliary surgery reviewed 20 computed tomography scans of patients without underlying liver pathology who were not scheduled for liver resection...
March 21, 2024: Surgery
https://read.qxmd.com/read/38519406/risk-factors-patterns-and-outcome-predictors-of-late-recurrence-in-patients-with-hepatocellular-carcinoma-after-curative-resection-a-large-cohort-study-with-long-term-follow-up-results
#31
JOURNAL ARTICLE
Chih-Yang Hsiao, Cheng-Maw Ho, Ming-Chih Ho, Hou-Ying Cheng, Yao-Ming Wu, Po-Huang Lee, Rey-Heng Hu
BACKGROUND: Late recurrence of hepatocellular carcinoma after curative resection significantly influences long-term patient survival outcomes, and yet it remains understudied. This study aims to explore the risk factors and patterns of late recurrence and predictors of subsequent outcome. METHODS: This single-center retrospective study analyzed 1,701 consecutive patients who achieved a disease-free survival period exceeding 2 years after curative resection for hepatocellular carcinoma between 2001 and 2018...
March 21, 2024: Surgery
https://read.qxmd.com/read/38519362/liver-volumetry-and-liver-regenerative-interventions-history-rationale-and-emerging-tools
#32
REVIEW
Antony Haddad, Mateo Lendoire, Harufumi Maki, Hyunseon Christine Kang, Peiman Habibollahi, Bruno C Odisio, Steven Y Huang, Jean-Nicolas Vauthey
BACKGROUND: Postoperative hepatic insufficiency (PHI) is the most feared complication after hepatectomy. Volume of the future liver remnant (FLR) is one objectively measurable indicator to identify patients at risk of PHI. In this review, we summarized the development and rationale for the use of liver volumetry and liver-regenerative interventions and highlighted emerging tools that could yield new advancements in liver volumetry. METHODS: A review of MEDLINE/PubMed, Embase, and Cochrane Library databases was conducted to identify literature related to liver volumetry...
February 15, 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38519001/stent-graft-placement-for-hepatic-artery-bleeding-after-pancreaticobiliary-surgery-long-term-clinical-outcomes
#33
JOURNAL ARTICLE
Yonghun Kim, Jin Hyoung Kim, Ji Hoon Kim, Gun Ha Kim, Heung-Kyu Ko, Hee Ho Chu, Ji Hoon Shin, Dong Il Gwon, Gi-Young Ko
PURPOSE: To evaluate the safety and long-term clinical outcomes of stent-graft placement to stop hepatic artery bleeding after pancreaticobiliary surgery. MATERIALS AND METHODS: Outcomes were retrospectively evaluated in 61 patients (50 men, 11 women; mean age, 63) who underwent stent-graft placement for delayed arterial bleeding (after 24 hours) after pancreaticobiliary surgery from 2006 to 2023. Bleeding sites included the gastroduodenal artery stump (n=54), the common or proper hepatic artery (n=5), and right hepatic artery (n=2)...
March 20, 2024: Journal of Vascular and Interventional Radiology: JVIR
https://read.qxmd.com/read/38518465/sirolimus-monotherapy-for-kasabach-merritt-phenomenon-in-a-neonate-case-report
#34
Shoji Nakamura, Michio Ozeki, Daichi Hayashi, Shiho Yasue, Saori Endo, Hidenori Ohnishi
INTRODUCTION AND IMPORTANCE: The Kasabach-Merritt Phenomenon (KMP), characterized by thrombocytopenia and consumptive coagulopathy due to endothelial cell growth in the infantile vascular tumor kaposiform hemangioendothelioma, presents a therapeutic challenge. This case highlights the novel use of sirolimus in a neonate, an approach less explored in this age group. CASE PRESENTATION: A female neonate presented with a right anterior chest mass, progressing to respiratory distress and congestive heart failure...
March 11, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38518211/two-stage-liver-transplantation-and-tricuspid-valve-replacement-after-blunt-trauma-in-a-pediatric-patient
#35
JOURNAL ARTICLE
Marshall W Wallace, Zachary J Kastenberg, Robert A Swendiman, Aaron W Eckhauser, Manuel Rodriguez-Davalos, Katie W Russell
In cases of uncontrollable hepatic hemorrhage or acute hepatic failure after trauma, liver transplantation can be a lifesaving procedure. Traumatic tricuspid valve injuries are rare, and symptoms can range from indolent to acute right heart failure. When concomitant, traumatic liver transplant and tricuspid injuries have significant physiologic interplay and management implications. We present a 14-year-old male injured in an all-terrain vehicle accident, who sustained a devastating disruption of the common bile duct and celiac artery injury, leading to acute hepatic failure, necessitating a two-stage liver transplantation...
March 22, 2024: American Surgeon
https://read.qxmd.com/read/38517202/microbially-conjugated-bile-salts-found-in-human-bile-activate-the-bile-salt-receptors-tgr5-and-fxr
#36
JOURNAL ARTICLE
Ümran Ay, Martin Leníček, Raphael S Haider, Arno Classen, Hans van Eijk, Kiran V K Koelfat, Gregory van der Kroft, Ulf P Neumann, Carsten Hoffmann, Carsten Bolm, Steven W M Olde Damink, Frank G Schaap
BACKGROUND: Bile salts of hepatic and microbial origin mediate interorgan cross talk in the gut-liver axis. Here, we assessed whether the newly discovered class of microbial bile salt conjugates (MBSCs) activate the main host bile salt receptors (Takeda G protein-coupled receptor 5 [TGR5] and farnesoid X receptor [FXR]) and enter the human systemic and enterohepatic circulation. METHODS: N-amidates of (chenodeoxy) cholic acid and leucine, tyrosine, and phenylalanine were synthesized...
April 1, 2024: Hepatology Communications
https://read.qxmd.com/read/38516765/effect-of-sarcopenia-on-the-prognosis-of-clinical-outcomes-in-patients-with-hepatocellular-carcinoma-after-hepatic-resection
#37
JOURNAL ARTICLE
Thanatchawan Polvieng, Sermsak Hongjinda, Anuparp Thienhiran, Pipit Burasakarn, Pusit Fuengfoo
BACKGROUND: We aimed to study the prognostic impact of sarcopenia on overall survival (OS), disease-free survival (DFS), and postoperative outcomes among patients with Hepatocellular carcinoma (HCC) who underwent curative hepatic resection. METHODS: Data were collected retrospectively from patients with HCC underwent curative hepatic resection and preoperative abdominal computed tomography (CT) at our institution between January 2010 and December 2020. Sarcopenia was evaluated by the skeletal muscle mass at the inferior direction of the third-lumbar-vertebra (L3) cross-sectional area based on preoperative CT imaging using software analysis...
March 22, 2024: American Surgeon
https://read.qxmd.com/read/38515943/current-landscape-of-preoperative-neoadjuvant-therapies-for-initial-resectable-colorectal-cancer-liver-metastasis
#38
REVIEW
Xiao-Fei Cheng, Feng Zhao, Dong Chen, Fan-Long Liu
Colorectal cancer liver metastasis (CRLM) presents a clinical challenge, and optimizing treatment strategies is crucial for improving patient outcomes. Surgical resection, a key element in achieving prolonged survival, is often linked to a heightened risk of recurrence. Acknowledging the potential benefits of preoperative neoadjuvant chemotherapy in managing resectable liver metastases, this approach has gained attention for its role in tumor downsizing, assessing biological behavior, and reducing the risk of postoperative recurrence...
February 21, 2024: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/38512644/combination-therapy-of-endoscopic-gastric-remodeling-with-glp-1ra-for-the-treatment-of-masld
#39
JOURNAL ARTICLE
Pichamol Jirapinyo, Aunchalee Jaroenlapnopparat, Stephen D Zucker, Christopher C Thompson
PURPOSE: The mainstay of treatment for metabolic dysfunction-associated steatotic liver disease (MASLD) is weight loss. Endoscopic gastric remodeling (EGR) and glucagon-like peptide-1 receptor agonist (GLP-1RA) are effective weight loss therapies. This study aims to assess the effect of combining EGR with GLP-1RA on liver-related outcomes and weight profile. MATERIALS AND METHODS: This is a retrospective study of a prospectively collected registry of patients with MASLD and compensated advanced chronic liver disease (cACLD) who underwent EGR...
March 21, 2024: Obesity Surgery
https://read.qxmd.com/read/38512350/ultrasound-guided-robotic-surgical-procedures-a-systematic-review
#40
REVIEW
Matteo Pavone, Barbara Seeliger, Elena Teodorico, Marta Goglia, Cristina Taliento, Nicolò Bizzarri, Lise Lecointre, Cherif Akladios, Antonello Forgione, Giovanni Scambia, Jacques Marescaux, Antonia C Testa, Denis Querleu
INTRODUCTION: Ultrasound has been nicknamed "the surgeon's stethoscope". The advantages of laparoscopic ultrasound beyond a substitute for the sense of touch are considerable, especially for robotic surgery. Being able to see through parenchyma and into vascular structures enables to avoid unnecessary dissection by providing a thorough assessment at every stage without the need for contrast media or ionising radiation. The limitations of restricted angulation and access within the abdominal cavity during laparoscopy can be overcome by robotic handling of miniaturised ultrasound probes and the use of various and specific frequencies will meet tissue- and organ-specific characteristics...
March 21, 2024: Surgical Endoscopy
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