Ka Loong Kelvin Au, Joshua K Wong, Takashi Tsuboi, Robert S Eisinger, Kathryn Moore, Janine Lemos Melo Lobo Jofili Lopes, Marshall T Holland, Vanessa M Holanda, Zhongxing Peng-Chen, Addie Patterson, Kelly D Foote, Adolfo Ramirez-Zamora, Michael S Okun, Leonardo Almeida
INTRODUCTION: The globus pallidus internus (GPi) region has evolved as a potential target for deep brain stimulation (DBS) in Parkinson's disease (PD). DBS of the GPi (GPi DBS) is an established, safe and effective method for addressing many of the motor symptoms associated with advanced PD. It is important that clinicians fully understand this target when considering GPi DBS for individual patients. METHODS: The literature on GPi DBS in PD has been comprehensively reviewed, including the anatomy, physiology and potential pitfalls that may be encountered during surgical targeting and post-operative management...
June 2021: Neurology and Therapy