keyword
https://read.qxmd.com/read/38545832/elevated-white-blood-cell-count-and-long-term-clinical-outcomes-of-patients-with-vasospastic-angina
#21
JOURNAL ARTICLE
Dong-Yeon Kim, Sung Eun Kim, Taek Kyu Park, Ki Hong Choi, Joo Myung Lee, Jeong Hoon Yang, Young Bin Song, Jin-Ho Choi, Hyeon-Cheol Gwon, Joo-Yong Hahn, Seung-Hyuk Choi, Sung Woo Cho
OBJECTIVES: Inflammation is known as one of key pathophysiologic mechanisms of coronary artery disease. We aimed to investigate the relationship between white blood cell (WBC) count and long-term clinical outcomes of patients with vasospastic angina (VA). METHODS: A total of 823 patients who were diagnosed as VA without significant coronary lesion by coronary angiography with ergonovine provocation test were enrolled for analysis. Patients were divided according to WBC count tertile at the time of diagnosis: group I, tertile 1 and 2 (n = 546, <7490/ml); group II, tertile 3 (n = 277, ≥7490/ml)...
March 28, 2024: Coronary Artery Disease
https://read.qxmd.com/read/38545804/salt-sensitive-hypertension-and-the-kidney
#22
REVIEW
Mitsuhiro Nishimoto, Karen Griffin, Brandi M Wynne, Toshiro Fujita
Salt-sensitive hypertension (SS-HT) is characterized by blood pressure elevation in response to high dietary salt intake and is considered to increase the risk of cardiovascular and renal morbidity. Although the mechanisms responsible for SS-HT are complex, the kidneys are known to play a central role in the development of SS-HT and the salt sensitivity of blood pressure (SSBP). Moreover, several factors influence renal function and SSBP, including the renin-angiotensin-aldosterone system, sympathetic nervous system, obesity, and aging...
March 28, 2024: Hypertension
https://read.qxmd.com/read/38545781/evolocumab-treatment-in-pediatric-patients-with-homozygous-familial-hypercholesterolemia-pooled-data-from-three-open-label-studies
#23
JOURNAL ARTICLE
Frederick J Raal, Robert A Hegele, Andrea Ruzza, J Antonio G López, Ajay K Bhatia, Johnny Wu, Huei Wang, Daniel Gaudet, Albert Wiegman, Jian Wang, Raul D Santos
BACKGROUND: Pediatric patients with homozygous familial hypercholesterolemia (HoFH) have an increased risk of atherosclerotic cardiovascular disease and difficulty meeting low-density lipoprotein cholesterol (LDL-C) goals. In this post hoc analysis, we evaluated pooled safety and efficacy data from 3 studies in pediatric patients with HoFH treated with the PCSK9 (proprotein convertase subtilisin/kexin type 9) monoclonal antibody inhibitor evolocumab. METHODS: Patients with HoFH aged 10 to 17 years received treatment with open-label evolocumab 420 mg subcutaneously monthly or biweekly in the TAUSSIG, RAMAN, or HAUSER-OLE clinical studies...
March 28, 2024: Arteriosclerosis, Thrombosis, and Vascular Biology
https://read.qxmd.com/read/38545775/advancing-wearable-biosensors-for-congenital-heart-disease-patient-and-clinician-perspectives-a-science-advisory-from-the-american-heart-association
#24
REVIEW
Animesh Tandon, Jennifer N Avari Silva, Ami B Bhatt, Colin K Drummond, Allison C Hill, Amanda E Paluch, Sheradon Waits, Jenny E Zablah, Kevin C Harris
Wearable biosensors (wearables) enable continual, noninvasive physiologic and behavioral monitoring at home for those with pediatric or congenital heart disease. Wearables allow patients to access their personal data and monitor their health. Despite substantial technologic advances in recent years, issues with hardware design, data analysis, and integration into the clinical workflow prevent wearables from reaching their potential in high-risk congenital heart disease populations. This science advisory reviews the use of wearables in patients with congenital heart disease, how to improve these technologies for clinicians and patients, and ethical and regulatory considerations...
March 28, 2024: Circulation
https://read.qxmd.com/read/38545773/impact-of-off-hour-admission-on-in-hospital-outcomes-for-patients-with-stroke-receiving-reperfusion-therapy-in-china
#25
JOURNAL ARTICLE
Zeyu Liu, Kaixuan Yang, Hongqiu Gu, Minping Wei, Xianjing Feng, Fang Yu, Yang Du, Zixiao Li, Jian Xia
BACKGROUND: The structure and staffing of hospitals greatly impact patient outcomes, with frequent changes occurring during nights and weekends. This retrospective cohort study assessed the impact of admission timing on in-hospital management and outcomes for patients with stroke receiving reperfusion therapy in China using data from a nationwide registry. METHODS: Data from patients receiving reperfusion therapy were extracted from the Chinese Stroke Center Alliance...
March 28, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38545743/a-meta-analysis-of-risk-factors-for-acute-kidney-injury-in-pneumonia-effectiveness-of-nursing-interventions
#26
REVIEW
Liangjuan Yuan, Arshad Mehmood, Lei Meng
INTRODUCTION: The spread of coronavirus disease 2019 (COVID-19) worldwide since November 2019 is of interest to understand its impact on various organs. COVID-19 patients experience a higher incidence of acute kidney injury (AKI) compared with non-COVID-19 patients. METHODS: A systematic literature search was conducted that covered the period from November 1, 2019 to February 28, 2021. RESULTS: The analysis incorporated a comprehensive review of 19 studies of 21 362 patients...
March 28, 2024: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/38545723/-not-available
#27
JOURNAL ARTICLE
Yosra Raddaoui, Ahmed Ben Amara, Aymen Noamen, Saoussen Antit, Youssef Hajri, Jamila Habli, Hassen Ibn Hadj Amor, Youssef Ben Youssef, Lilia Zakhama, Wafa Fehri
RESEARCH PROBLEM: Hypertension is a multifactorial disease that affects approximately one third of the Tunisian adult population. It is a major risk factor for stroke and cardiovascular disease. Environmental and psychosocial factors play an important role in hypertension onset and control. The prevalence of depression among hypertensive patients is 26, 8% and its presence is associated with increased risk of cardiovascular related morbi-mortality. Our study aims to evaluate the role of depression in blood pressure control among ambulatory hypertensive patients...
January 5, 2024: La Tunisie Médicale
https://read.qxmd.com/read/38545713/-not-available
#28
JOURNAL ARTICLE
Sarra Laabidi, Mouna Medhioub, Amal Khsiba, Asma Bach Ali, Asma Ben Mohamed, Lamine Hamzaoui
INTRODUCTION: The impact of direct antiviral drugs (DAAs) on extrahepatic manifestations in chronic hepatitis C (CHC) has been poorly studied. AIM: To assess the prevalence of subclinical atherosclerosis in patients with CHC and the impact of DAAs on atherosclerotic lesions. Methods A 5-year prospective evaluative study, including patients followed for CHC at hepato-gastroenterology department. The subclinical atherosclerosis was assessed by ultrasound measurement of carotid intima-media thickness (IMTc) and the highest IMTc measurements from the left and right side defined the IMTc maximum (IMTc max)...
March 5, 2024: La Tunisie Médicale
https://read.qxmd.com/read/38545710/-not-available
#29
JOURNAL ARTICLE
Faten El Ayech Boudiche, Selim Boudiche, Safia Othmani, Hajer Mehri, Malek Larbi, Ahmed Omar Yaakoub, Leila Bezdah
INTRODUCTION: Despite the demonstrated efficacy of cardiovascular (CV) preventive measures, data from international literature indicate that control of CV risk factors (RF) remains insufficient in very high-risk patients. AIM: This study aimed to assess prevalence of achievement of recommended therapeutic targets for the major and modifiable CVRF 12 months after myocardial infarction (MI). METHODS: From 1st January to 30th April 2023, we collected consecutive patients with type 1 MI who had completed 12 months follow-up...
March 5, 2024: La Tunisie Médicale
https://read.qxmd.com/read/38545682/retrieval-of-a-left-appendage-device-from-the-left-ventricle-using-a-large-bore-steerable-catheter
#30
Abou-Bakr Abbadi, Mariama Akodad, Jérôme Horvilleur, Antoinette Neylon
Left atrium appendage closure is a safe and effective therapy for patients with atrial fibrillation and high thromboembolic and hemorrhagic risks. Prosthesis embolization is a potential major complication with an incidence of 0.07%. We report a case of migration of an Amplatzer Amulet (Abbott) device that was successfully retrieved in an innovative way (4).
March 28, 2024: Catheterization and Cardiovascular Interventions
https://read.qxmd.com/read/38545668/balloon-rupture-during-transcatheter-aortic-valve-replacement
#31
REVIEW
Craig Basman, David Landers, Chad Kliger, Karla Rodriguez-Barragan, Sung-Han Yoon, Haroon Faraz, Ankitkumar Patel, Yuriy Dudiy, Mark Anderson, Ryan Kaple
A distinctive complication with balloon-expandable (BE) THV platforms such as the Edwards Sapien (Edwards Lifescience) is the possibility of balloon rupture during THV deployment. Balloon rupture is a rare occurrence that can result in stroke due to fragment embolism, incomplete THV expansion, and/or vascular injury upon retrieval of the balloon. Careful evaluation of preoperative computed tomography is essential to identify high-risk cases. While annular and left ventricular outflow tract (LVOT) calcification are widely acknowledged as common risks for balloon injury, it's essential to note that balloon injury can manifest at various anatomical sites...
March 28, 2024: Catheterization and Cardiovascular Interventions
https://read.qxmd.com/read/38545667/siewert-ii-esophagogastric-junction-adenocarcinoma-still-searching-for-the-right-treatment-transabdominal-or-transthoracic-surgical-approaches
#32
REVIEW
Mohamed Maatouk, Mariem Nouira, Anis Ben Dhaou, Ghassen Hamdi Kbir, Aymen Mabrouk, Mohamed Ben Khlifa, Sami Daldoul, Sofien Sayari, Mounir Ben Moussa
INTRODUCTION: To date, the discussion is still ongoing whether the Siewert II adenocarcinoma of the esophagogastric junction (AEG) should be resected either by thoracoabdominal esophagectomy or gastrectomy with resection of the distal esophagus by transhiatal extension. The aim of our study was to compare the oncological and perioperative outcomes of the transthoracic approach (TTA) and the transabdominal approach (TAA). METHODS: Searches of electronic databases identifying studies from Cochrane, PubMed and Google Scholar were performed...
March 28, 2024: Asian Cardiovascular & Thoracic Annals
https://read.qxmd.com/read/38545427/long-term-impact-of-home-based-monitoring-after-an-admission-for-acute-decompensated-heart-failure-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#33
JOURNAL ARTICLE
Mariana R C Clemente, Nicole Felix, Denilsa D P Navalha, Eric Pasqualotto, Rafael Oliva Morgado Ferreira, Marcelo A P Braga, Alleh Nogueira, Thomaz Alexandre Costa, Alice D Marinho, Amanda Fernandes
BACKGROUND: Patients with heart failure have high rehospitalisation rates and poor cardiovascular outcomes. Home-based monitoring (HBM) has emerged with promising results in different settings. However, its long-term effects on patients recently admitted for acute decompensated heart failure (ADHF) remain uncertain. METHODS: We systematically searched PubMed, Embase, and Cochrane Library for randomised controlled trials (RCTs) comparing HBM with usual care (UC) that were published between database inception and June 24, 2023...
May 2024: EClinicalMedicine
https://read.qxmd.com/read/38545364/anomalous-origin-of-left-coronary-artery-from-the-pulmonary-artery-our-30-years-of-surgical-experience-and-outcomes
#34
JOURNAL ARTICLE
Chaganti Yogi Sundara Rao, A Aravind, Desai Nelam
Background: The aim of this study was to evaluate our 30 years of surgical experience and outcomes in management of anomalous origin of left coronary artery from the pulmonary artery with various age groups. Methods: Between March 1992 and August 2022, a total of 21 patients (10 males, 11 females; mean age: 16.3±15.9 years; range, 1 to 64 years) diagnosed with anomalous origin of left coronary artery from the pulmonary artery who underwent successful surgical repair were retrospectively analyzed. An initial diagnosis was made with two-dimensional echocardiography...
January 2024: Türk Göğüs Kalp Damar Cerrahisi Dergisi
https://read.qxmd.com/read/38545361/association-of-body-mass-index-with-clinical-outcomes-in-patients-with-acute-coronary-syndrome-a-systematic-review-and-meta-analysis
#35
JOURNAL ARTICLE
Man Wang, Xun Wei, Maolin Zhao
BACKGROUND: In this meta-analysis, we aimed to systematically examine the relationship between body mass index and major adverse cardiovascular events in acute coronary syndrome patients and to provide theoretical guidance for body weight management in these patients. METHODS: A comprehensive analysis of applicable research published between 2008 and 2021 was conducted using the PubMed, Cochrane, Web of Science, Wanfang, and CNKI databases. Extracted odds ratios from the randomized-controlled studies were pooled using fixed-effects meta-analysis...
January 2024: Türk Göğüs Kalp Damar Cerrahisi Dergisi
https://read.qxmd.com/read/38545358/postoperative-pulmonary-complications-in-awake-video-assisted-thoracoscopic-surgery-our-10-year-experience
#36
JOURNAL ARTICLE
Özlem Turhan, Nükhet Sivrikoz, Salih Duman, Murat Kara, Zerrin Sungur
BACKGROUND: The aim of this study was to evaluate the effect of awake video-assisted thoracoscopic surgery on postoperative pulmonary complications among patients with different risk scores using the Assess Respiratory Risk in Surgical Patients in Catalonia (ARISCAT). METHODS: Between January 2011 and August 2021, a total of 246 patients (158 males, 88 females; mean age: 59.1±13.6 years; range, 25 to 84 years) who underwent awake video-assisted thoracoscopic surgery were retrospectively analyzed...
January 2024: Türk Göğüs Kalp Damar Cerrahisi Dergisi
https://read.qxmd.com/read/38545353/impact-of-preoperative-scores-on-postoperative-process-in-bronchiectasis-surgery
#37
JOURNAL ARTICLE
Ali Murat Akçıl, Onur Volkan Yaran, Levent Cansever, Cemal Aker, Yunus Seyrek, Mehmet Ali Bedirhan
BACKGROUND: In this study, we aimed to investigate the relationship between bronchiectasis criteria, scores, and indices used today and surgical interventions due to bronchiectasis. METHODS: Between January 2009 and December 2018, a total of 106 patients (53 males, 53 females; mean age: 39.1±12.3 years; range, 14 to 68 years) with non-cystic fibrous bronchiectasis were retrospectively analyzed. We determined symptom improvement and complications as main factors...
January 2024: Türk Göğüs Kalp Damar Cerrahisi Dergisi
https://read.qxmd.com/read/38545347/construction-of-a-nomogram-risk-prediction-model-for-prolonged-mechanical-ventilation-in-patients-following-surgery-for-acute-type-a-aortic-dissection
#38
JOURNAL ARTICLE
Yun Yu, Yan Wang, Fang Deng, Zhigang Wang, Beibei Shen, Ping Zhang, Zheyun Wang, Yunyan Su
BACKGROUND: This study aims to analyze the risk factors associated with prolonged mechanical ventilation (PMV) in patients following surgical treatment for acute type A aortic dissection (ATAAD). The objectives include constructing a predictive model for risk assessment and validating its predictive efficacy. METHODS: A total of 452 patients diagnosed with ATAAD and undergoing surgical procedures at a tertiary hospital in Nanjing between January 2021 and April 2023 were selected using a convenience sampling method...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38545345/lipoprotein-a-as-a-risk-factor-for-atherosclerotic-cardiovascular-disease-in-patients-in-non-metropolitan-areas-of-brandenburg-germany
#39
JOURNAL ARTICLE
Philipp Hillmeister, Kangbo Li, Mengjun Dai, Mesud Sacirovic, Nikolaos Pagonas, Oliver Ritter, Peter Bramlage, Anja Bondke Persson, Ivo Buschmann, Claudia Zemmrich
BACKGROUND AND AIMS: In the non-metropolitan region of Brandenburg (Germany), which is characterized by high rates of cardiovascular diseases and underserved medical care, there is a lack of awareness regarding lipoprotein(a) [Lp(a)] as a risk factor. In addition, data from patients with atherosclerotic cardiovascular disease (ASCVD) in diverse regional backgrounds, including the understudied Brandenburg cohort, and various healthcare statuses remain insufficient. METHODS: In this WalkByLab study, Lp(a) levels were monitored in a non-metropolitan cohort ( n  = 850) in Brandenburg, Germany, comprising 533 patients at high cardiovascular risk and 317 healthy controls...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38545344/effect-of-statin-add-on-therapy-on-cardiovascular-mortality
#40
REVIEW
John R Nelson, Viet Le, Jeffrey L Anderson, Nicole Ciffone
INTRODUCTION: Cardiovascular (CV) disease remains a leading cause of mortality despite statin therapy. Statin add-on lipid-lowering therapies have been investigated for CV risk reduction, but their effect on CV mortality has not been reviewed. METHODS: This review describes CV outcomes trials of add-on therapies to statins, highlighting findings related to the primary composite CV endpoints and the more patient-centric endpoint of CV-related mortality. RESULTS: Add-on ezetimibe met its primary composite CV endpoint vs...
2024: Frontiers in Cardiovascular Medicine
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