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https://read.qxmd.com/read/30775097/phantom-study-of-a-fiber-optic-force-sensor-design-for-biopsy-needles-under-mri
#1
Nurettın Okan Ulgen, Dogangun Uzun, Ozgur Kocaturk
Biopsy needles with embedded force sensors can eliminate the needle deflection and the needle targeting failure risks during MRI guided biopsy procedures. Fabry-Pérot interferometry (FPI) based sensors are small, compact and immune to electromagnetic and RF interferences, and therefore they are suitable for needle guidance under MRI. In this work, an FPI based fiber optic force sensor design and its integration to an 18-gauge MRI compatible biopsy needle are presented. The custom designed FPI sensor provides a force measurement range up to 13 N with a resolution of 0...
January 1, 2019: Biomedical Optics Express
https://read.qxmd.com/read/30738625/epidermal-growth-factor-enhances-spinal-fusion-posterolateral-lumbar-fusion-model-on-rats
#2
Engin Çetin, İsmail Daldal, Ali Eren, Saadet Özen Akarca Dizakar, Suna Ömeroğlu, Bora Uzuner, Hakan Hamdi Çelik, Hasan Hüseyin Saygılı, Benat Koçkar, Alpaslan Şenköylü
OBJECTIVE: The aim of this study was to investigate the effects of human recombinant epidermal growth factor (EGF) on posterolateral lumbar fusion in a rat model. METHODS: 36 male Sprague Dawley rats underwent posterolateral fusion at L4-5 level. They were randomly assigned to 3 groups: 1- Sham control group where no local augmentation was made, 2- Local Hydoxyapatite β-tricalcium phosphate (HA/β-TCP) augmentation group and 3- Local HA/β-TCP + EGF augmentation group...
February 6, 2019: Acta Orthopaedica et Traumatologica Turcica
https://read.qxmd.com/read/30713471/effect-of-methylation-of-ionic-liquids-on-the-gas-separation-performance-of-ionic-liquid-metal-organic-framework-composites
#3
Vahid Nozari, Muhammad Zeeshan, Seda Keskin, Alper Uzun
1- N -Butyl-3-methylimidazolium hexafluorophosphate, [BMIM][PF6 ], and its methylated form, 1- N -butyl-2,3-dimethylimidazolium hexafluorophosphate, [BMMIM][PF6 ], were incorporated into CuBTC to examine the effect of methylation of ionic liquids (ILs) on the gas separation performance of the corresponding IL/metal-organic framework (MOF) composites. Spectroscopic analysis revealed that the interactions of the methylated ILs with CuBTC were weaker compared to those of its non-methylated counterpart. Gas uptake measurements illustrated that this difference in the interactions influences the gas separation performance of the composites...
November 28, 2018: CrystEngComm
https://read.qxmd.com/read/30656803/unusual-facio-upper-arm-band-of-a-fetus-mimicking-amniotic-band-syndrome
#4
Cihan Inan, N Cenk Sayin, Hakan Gurkan, Selen G Erzincan, Isil Uzun, Havva Sutcu, Engin Atli, Fusun Varol
Amniotic band syndrome can lead to a wide spectrum of congenital abnormalities including orofacial and visceral defects. It is associated with malformations in truncal, craniofacial regions and the limbs, whereas it sometimes may imitate some genetic disorders. Here, we present an atypical case mimicking amniotic band syndrome with a facio-upper arm band that was having multiple fetal structural abnormalities including scoliosis, bilateral cleft lip and palate, upper limb abnormality, unilateral anophthalmia with contralateral microphthalmia, left hypertrophic kidney and severe ventriculomegaly...
January 18, 2019: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/30612874/the-long-term-outcomes-following-the-application-of-intralesional-epidermal-growth-factor-in-patients-with-diabetic-foot-ulcers
#5
Murat Kahraman, Abdulhamit Misir, Turan Bilge Kizkapan, Mustafa Ozcamdalli, Erdal Uzun, Mahmut Mutlu
Epidermal growth factor is used as an adjuvant to close the wound in addition to standard care in diabetic foot ulcers. This study aimed to investigate the long-term outcomes after intralesional epidermal growth factor injections in the treatment of diabetic foot ulcers. Thirty-six feet of 34 patients (n = 34) with diabetic foot ulcers were included. Patient demographics, Wagner classifications, recurrence and amputation rates, Foot Function Index, Short Form 36, and American Academy of Orthopedic Surgeons Foot and Ankle Module scores were evaluated at the final follow-up examination...
January 3, 2019: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://read.qxmd.com/read/30587428/l-arginine-metabolism-before-and-after-10-weeks-of-antipsychotic-treatment-in-first-episode-psychotic-patients
#6
Beyazit Garip, Hakan Kayir, Ozcan Uzun
Agmatine is an endogenous NMDA (N-methyl-d-aspartate) antagonist which is synthesized from l-Arginine and described as a novel neurotransmitter. Agmatine is considered to play an important role for the development of schizophrenia. The aim of the present study is to explore the role of agmatine and l-arginine metabolism in medication-naive first-episode psychosis (FEP). We conducted a case control study in medication-naive patients with FEP (n = 40). The healthy volunteers with no family history of schizophrenia (n = 35) matched for age, gender and education level were selected as a control group...
December 23, 2018: Schizophrenia Research
https://read.qxmd.com/read/30545550/deletion-of-macro-domain-containing-2-macro-d2-associated-with-transient-hydrops-fetalis
#7
I Uzun Çilingir, N C Sayin, H Gurkan, N A Çiftdemir, E Atlı, C İnan, S Erzincan, H Sutcu, U Vatansever, F Varol
No abstract text is available yet for this article.
December 2018: Taiwanese Journal of Obstetrics & Gynecology
https://read.qxmd.com/read/30535072/clinical-presentation-and-survival-of-childhood-hypertrophic-cardiomyopathy-a-retrospective-study-in-united-kingdom
#8
Gabrielle Norrish, Ella Field, Karen Mcleod, Maria Ilina, Graham Stuart, Vinay Bhole, Orhan Uzun, Elspeth Brown, Piers E F Daubeney, Amrit Lota, Katie Linter, Sujeev Mathur, Tara Bharucha, Khoon Li Kok, Satish Adwani, Caroline B Jones, Zdenka Reinhardt, Juan Pablo Kaski
Aims: Understanding the spectrum of disease, symptom burden and natural history are essential for the management of children with hypertrophic cardiomyopathy (HCM). The effect of changing screening practices over time has not previously been studied. This study describes the clinical characteristics and outcomes of childhood HCM over four decades in a well-characterized United Kingdom cohort. Methods and results: Six hundred and eighty-seven patients with HCM presented at a median age of 5...
December 6, 2018: European Heart Journal
https://read.qxmd.com/read/30501905/the-efficiency-of-the-symptom-based-score-in-infants-diagnosed-with-cow-s-milk-protein-and-hen-s-egg-allergy
#9
Seda Sirin Kose, G Atakul, S Asilsoy, N Uzuner, O Anal, O Karaman
INTRODUCTION AND OBJECTIVES: Symptom-based score (SBS) quantifies the number and severity of suspected cow's milk-related symptoms. In this study, we aimed to evaluate the efficiency of SBS in patients diagnosed with cow's milk protein (CMPA) and hen's egg allergy (HEA). MATERIALS AND METHODS: A single-center study was conducted between June 2015 and August 2017. Infants who were diagnosed with CMPA and HEA or both were enrolled in the study. SBS was applied at baseline and at one month during an elimination diet...
November 27, 2018: Allergologia et Immunopathologia
https://read.qxmd.com/read/30412694/the-current-clinical-and-geographical-situation-of-cutaneous-leishmaniasis-based-on-species-identification-in-turkey
#10
Ahmet Özbilgin, Seray Töz, Mehmet Harman, Suhan Günaştı Topal, Soner Uzun, Fulya Okudan, Dilek Güngör, Ayşegül Erat, Hatice Ertabaklar, Sema Ertuğ, Cumhur Gündüz, İbrahim Çavuş, Mehmet Karakuş, İpek Östan Ural, M Kirami Ölgen, Çağla Kayabaşı, Özgür Kurt, Yusuf Özbel
Leishmaniases are a group of vector-borne diseases caused by the members of Leishmania genus, and there are three main clinical forms of the infection as visceral, cutaneous, and mucocutaneous. Cutaneous leishmaniasis is a growing public health problem in Turkey due to increasing detection of autochthonous cases caused by L. major and L. donovani in some regions in addition to Syrian imported cases. For this reason, we aimed to evaluate the current epidemiological situation of CL in the view of causative agents and their geographical distribution throughout Turkey...
November 6, 2018: Acta Tropica
https://read.qxmd.com/read/30384291/removal-of-wastewater-and-polymer-derived-n-nitrosodimethylamine-precursors-with-integrated-use-of-chlorine-and-chlorine-dioxide
#11
Habibullah Uzun, Daekyun Kim, Tanju Karanfil
In this study, the effects of five different pre-oxidation scenarios (i.e., individual, simultaneous, and sequential applications of chlorine dioxide [ClO2 ] and chlorine [Cl2 ]) on the removal of N-nitrosodimethylamine (NDMA) formation potential (FP) from different water matrices (i.e., non-impacted natural waters, wastewater [WW]-impacted, and polymer-impacted waters) with subsequent chloramination were investigated. Practically relevant doses of ClO2 and Cl2 were applied for all scenarios to avoid the formation of disinfection by-products (DBPs) at regulatory levels...
February 2019: Chemosphere
https://read.qxmd.com/read/30368740/predictors-of-unfavorable-outcome-in-neurosyphilis-multicenter-id-iri-study
#12
Derya Ozturk-Engin, Hakan Erdem, Rodrigo Hasbun, Shu-Hua Wang, Hulya Tireli, Pierre Tattevin, Xavier Argemi, Enora Ouamara-Digue, Andrea Gombos, Botond Lakatos, Fatma Sırmatel, Yasemin Cag, Abdullah Umut Pekok, Seniha Senbayrak, Ilker Inanç Balkan, Marie Gheno, Nuray Uzun, Selçuk Kaya, Gönül Cicek-Senturk, Gönül Şengöz, Recep Tekin, Mustafa Kemal Çelen, Saygın Nayman-Alpat, Pınar Ergen, Alper Şener, Canan Agalar, Sükran Köse, Ahmet Çagkan Inkaya, Figen Kaptan, Fahad Al-Majid, Umit Savasci, Haluk Vahaboglu
Neurosyphilis (NS) has different clinical manifestations and can appear during any stage of syphilis. We aimed to identify the factors affecting poor outcome in NS patients. Patients with positive cerebrospinal fluid Venereal Disease Research Laboratory test, and positive serological serum treponemal or nontreponemal tests were classified as definite NS. The data of 141 patients with definite NS were submitted from 22 referral centers. Asymptomatic NS, syphilitic meningitis, meningovascular syphilis, tabes dorsalis, general paresis, and taboparesis were detected in 22 (15...
October 27, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://read.qxmd.com/read/30321789/the-relation-of-fetal-colon-and-rectum-diameters-with-labor-in-healthy-late-third-trimester-pregnancies
#13
Cihan Inan, N Cenk Sayin, Z Nihal Dolgun, Selen Gursoy Erzincan, Isil Uzun, Havva Sutcu, Fusun Varol
OBJECTIVE: To investigate the associations of fetal colon-rectum diameters with labor and fetal distress or meconium passage in healthy pregnancies in the late 3rd trimester. STUDY DESIGN: A total of 162 healthy, singleton pregnant women at ≥360/7 weeks who were in the latent-phase of labor (n = 69) or those not in labor (n = 93, controls) at the time of ultrasound examination were enrolled. Fetal colon (ascending, transverse, descending, sigmoid) and rectum diameters, Doppler indices of materno-fetal vessels were measured...
October 9, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/30280507/alterations-in-cerebral-blood-flow-in-children-with-congestive-heart-failure-due-to-ventricular-septal-defect
#14
Nurdan Ozturk Tasar, Pelin Kosger, Nevzat Uzuner, Birsen Ucar
OBJECTIVE: We aimed to investigate the effect of ventricular septal defect (VSD) and heart failure on cerebral blood flow (CBF) in children, whether heart failure treatment improves CBF, and if there is any relationship between CBF and serum N-terminal pro-brain natriuretic peptide (NT-proBNP) level. METHOD: Forty children with VSD (13 with heart failure) aged between 1 and 36 months were studied. The control group comprised 25 healthy children in the same age group...
October 2, 2018: Congenital Heart Disease
https://read.qxmd.com/read/30238582/angioedema-is-an-unfavorable-factor-for-the-response-to-omalizumab-in-chronic-spontaneous-urticaria-a-retrospective-study
#15
Gamze Serarslan, Mehmet Uzun, Asena Çiğdem Doğramacı, Ebru Çelik
Antihistamines are the first-line treatment option for chronic urticaria. In recent years, omalizumab, an anti-immunoglobulin-E humanized monoclonal antibody, has been used in patients with recalcitrant disease. The present study aimed to retrospectively evaluate the efficacy and safety of omalizumab and determine whether there was a difference between complete and partial responses to omalizumab with respect to age, gender, disease duration and coexistence of angioedema. From May 2014 to December 2016, a total of 40 refractory chronic urticaria patients were treated with omalizumab...
September 20, 2018: Dermatologic Therapy
https://read.qxmd.com/read/30213376/corrigendum-to-symptom-severity-prediction-from-neuropsychiatric-clinical-records-overview-of-2016-cegs-n-grid-shared-tasks-track-2-j-biomed-inform-2017-nov-75s-s62-s70
#16
Michele Filannino, Amber Stubbs, Özlem Uzuner
No abstract text is available yet for this article.
September 2018: Journal of Biomedical Informatics
https://read.qxmd.com/read/30159625/outbreak-of-shiga-toxin-producing-escherichia-coli-associated-hemolytic-uremic-syndrome-in-istanbul-in-2015-outcome-and-experience-with-eculizumab
#17
Ayşe Ağbaş, Nilüfer Göknar, Nurver Akıncı, Zeynep Yürük Yıldırım, Mehmet Taşdemir, Meryem Benzer, İbrahim Gökçe, Cengiz Candan, Nuran Küçük, Selçuk Uzuner, Gül Özçelik, Demet Demirkol, Lale Sever, Salim Çalışkan
BACKGROUND: This study aims to identify epidemiological and clinical characteristics of patients and report our experience with eculizumab treatment during an outbreak of hemolytic uremic syndrome (HUS) caused by Shiga toxin-producing Escherichia coli (STEC) in Istanbul in 2015. METHODS: Thirty-two children (21 females, median age 3.25 years) were included in this study. Demographic, clinical and laboratory data, and treatment details were retrospectively collected...
December 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://read.qxmd.com/read/30102479/knowledge-levels-related-to-allergen-specific-immunotherapy-and-perspectives-of-parents-whose-children-were-diagnosed-with-asthma-and-or-allergic-rhinitis-in-turkey
#18
Sakine Işık, Şule Çağlayan-Sözmen, Suna Asilsoy, Serdar Kamer Kılıçarslan, Özden Anal, Özkan Karaman, Nevin Uzuner
Işık S, Çağlayan-Sözmen Ş, Asilsoy S, Kılıçarslan SK, Anal Ö, Karaman Ö, Uzuner N. Knowledge levels related to allergen specific immunotherapy and perspectives of parents whose children were diagnosed with asthma and/or allergic rhinitis in Turkey. Turk J Pediatr 2018; 60: 50-55. In the present study, we aimed to evaluate the knowledge levels and perspectives about allergen specific immunotherapy (ASI) of parents whose children were diagnosed with asthma and/or allergic rhinitis with positive skin prick test...
2018: Turkish Journal of Pediatrics
https://read.qxmd.com/read/30067481/life-threatening-event-risk-in-children-with-wolff-parkinson-white-syndrome-a-multicenter-international-study
#19
Susan P Etheridge, Carolina A Escudero, Andrew D Blaufox, Ian H Law, Brynn E Dechert-Crooks, Elizabeth A Stephenson, Anne M Dubin, Scott R Ceresnak, Kara S Motonaga, Jonathan R Skinner, Luciana D Marcondes, James C Perry, Kathryn K Collins, Stephen P Seslar, Michel Cabrera, Orhan Uzun, Bryan C Cannon, Peter F Aziz, Peter Kubuš, Ronn E Tanel, Santiago O Valdes, Sara Sami, Naomi J Kertesz, Jennifer Maldonado, Christopher Erickson, Jeremy P Moore, Hiroko Asakai, LuAnn Mill, Mark Abcede, Zebulon Z Spector, Shaji Menon, Mark Shwayder, David J Bradley, Mitchell I Cohen, Shubhayan Sanatani
OBJECTIVES: This study sought to characterize risk in children with Wolff-Parkinson-White (WPW) syndrome by comparing those who had experienced a life-threatening event (LTE) with a control population. BACKGROUND: Children with WPW syndrome are at risk of sudden death. METHODS: This retrospective multicenter pediatric study identified 912 subjects ≤21 years of age with WPW syndrome, using electrophysiology (EPS) studies. Case subjects had a history of LTE: sudden death, aborted sudden death, or atrial fibrillation (shortest pre-excited RR interval in atrial fibrillation [SPERRI] of ≤250 ms or with hemodynamic compromise); whereas subjects did not...
April 2018: JACC. Clinical Electrophysiology
https://read.qxmd.com/read/30036122/association-of-plasma-pentraxin-3-levels-with-retinopathy-and-systemic-factors-in-diabetic-patients
#20
Füsun Erdenen, Hülya Güngel, Esma Altunoğlu, Duygu Şak, Cüneyt Müderrisoğlu, Atakan Koro, Pınar Akça Güler, Muzaffer Ece Hakan Sahin, Gonul Simsek, Hafize Uzun
BACKGROUND: Diabetic retinopathy (DR) is mainly caused by metabolic factors, vascular inflammation, and endothelial dysfunction. We aimed to evaluate the relationship of DR with inflammatory and biochemical alterations in type 2 diabetics. METHODS: A total of 89 diabetic patients with retinopathy [(DR (+) (n = 30)], without retinopathy [(DR (-) (n = 32)], and 27 control subjects were involved in the study. Demographic properties, biochemical values, ophtalmologic evaluation, C-reactive protein (CRP), and pentraxin-3 (PTX-3) levels were recorded...
September 2018: Metabolic Syndrome and related Disorders
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