Mingliang Gao, Jinshan Lan, Yuling Zha, Weifeng Yao, Beihua Bao, Mingqiu Shan, Fang Zhang, Guisheng Zhou, Sheng Yu, Fangfang Cheng, Yudan Cao, Hui Yan, Li Zhang, Peidong Chen
Four fractions of polysaccharides (TPP-1, TPP-2, TPP-3, and TPP-4) were isolated and purified from the pollen of Typha angustifolia L., and the structure of TPP-3 was furtherly determined by HPGPC (High Performance Gel Permeation Chromatography), monosaccharide composition analysis, methylation analysis and NMR (Nuclear Magnetic Resonance). TPP-3 was found to be a homogeneous heteropolysaccharide with an average molecular weight of 5.5 × 104 Da and composed of eight types of monosaccharides. The pro-angiogenic activities of TPP-3 were verified on HUVECs and VEGFR tyrosine kinase inhibitor II (VRI)-induced vascular defect zebrafish model...
October 6, 2022: International Journal of Biological Macromolecules