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Spasticity AND Cerebral Palsy

Eva Pontén, Ferdinand von Walden, Catarina Lenke-Ekholm, Britt-Marie Zethraeus, Ann-Christin Eliasson
To evaluate whether short-term positive effects on bimanual function after surgery of the paretic arm in cerebral palsy are maintained long term. Assisting Hand Assessment (AHA) and active range of motion was tested before surgery and at 7 month and 9-year follow-up (n=18). AHA improved significantly from 50 to 52 U at 7 months, but was not different from before surgery at the 9-year follow-up, 49 U. Surgery of wrist and elbow flexors significantly improved active extension. Improvement in wrist and elbow extension was maintained at the 9-year follow-up, but usefulness of the hand measured with AHA had returned to the same level as before surgery...
February 12, 2019: Journal of Pediatric Orthopedics. Part B
Kürşad Aydın, Ayşe Kartal, Esma Keleş Alp
Background/aim: The aim of this study was to evaluate the nutritional status of children with cerebral palsy and determine the particular characteristics of the disorder. Materials and methods: The nutritional status of the children was assessed by the Gomez classification using weight-for-age. The Gross Motor Function Classification System was used to determine the gross and fine motor functions. Results: The study was conducted with 197 children (58...
February 11, 2019: Turkish Journal of Medical Sciences
Mark Gormley
No abstract text is available yet for this article.
February 14, 2019: Developmental Medicine and Child Neurology
Roberta Paiva Magalhães Ortega, Sérgio Rosemberg
AIMS: To investigate hereditary spastic paraplegia (HSP) in a pediatric Brazilian sample. METHODS: Epidemiological, clinical, radiological and laboratory data were analyzed in 35 patients. RESULTS: Simple HSP (HSP-S) was detected in 12 patients, and complicated HSP (HSP-C) was detected in 23 patients. The mean age of onset of symptoms was 2.9 years in HSP-S and 1.6 years in HSP-C (p = 0.023). The disease was more severe in HSP-C. There were no differences in sex, ethnic background, or family history between groups...
January 2019: Arquivos de Neuro-psiquiatria
Helle M Rasmussen, Niels W Pedersen, Søren Overgaard, Lars K Hansen, Ulrike Dunkhase-Heinl, Yanko Petkov, Vilhelm Engell, Anders Holsgaard-Larsen
AIM: To test the hypothesis that improvements in gait and function following individualized interdisciplinary interventions consisting of physical therapy, orthotics, spasticity management, and orthopaedic surgery using instrumented gait analysis are superior to 'usual care' in children with cerebral palsy (CP). METHOD: This was a prospective, single-blind, parallel-group, randomized controlled trial investigating the effectiveness of interventions based on the use of gait analysis...
February 10, 2019: Developmental Medicine and Child Neurology
Cally J Tann, Emily L Webb, Rachel Lassman, Julius Ssekyewa, Margaret Sewegaba, Margaret Musoke, Kathy Burgoine, Cornelia Hagmann, Eleanor Deane-Bowers, Kerstin Norman, Jack Milln, Jennifer J Kurinczuk, Alison M Elliott, Miriam Martinez-Biarge, Margaret Nakakeeto, Nicola J Robertson, Frances M Cowan
Background: Neonatal encephalopathy (NE) is a leading cause of global child mortality. Survivor outcomes in low-resource settings are poorly described. We present early childhood outcomes after NE in Uganda. Methods: We conducted a prospective cohort study of term-born infants with NE (n = 210) and a comparison group of term non-encephalopathic (non-NE) infants (n = 409), assessing neurodevelopmental impairment (NDI) and growth at 27-30 months. Relationships between early clinical parameters and later outcomes were summarised using risk ratios (RR)...
December 2018: EClinicalMedicine
David Graham, Simon P Paget, Neil Wimalasundera
Cerebral palsy is a developmental disorder of movement and posture which is often associated with comorbidities. While there is currently a limited range of evidence-based treatments that change the underlying pathology of cerebral palsy, there are many areas in which health care professionals can change the natural history of cerebral palsy and improve participation and quality of life for children with this condition. Early identification has become of paramount importance in the management of cerebral palsy, and it is hoped that it will allow earlier access to cerebral palsy interventions that may improve the natural history of the condition...
February 10, 2019: Medical Journal of Australia
Alexander Marcström, Gunnar Hägglund, Ann I Alriksson-Schmidt
BACKGROUND: Hip pain is prevalent in children with cerebral palsy (CP). Hip displacement is a known risk factor for hip pain. However, many children do not have displaced hips but still have hip pain and the aetiologies are poorly understood. The aims of this study were to investigate: 1. the prevalence of hip pain related to age, gender, gross motor function, degree of hip displacement and 2. the associations between hip pain and age, gender, gross motor function, degree of hip displacement, ranges of hip and knee motion (ROM) and degree of spasticity in the muscles around the hip...
February 8, 2019: BMC Musculoskeletal Disorders
Rachel Helena Silva de Oliveira, Marina de Brito Brandão, Juliana Vaz de Melo Mambrini, Marisa Cotta Mancini
BACKGROUND: Many bimanual activities are challenging for children with unilateral spastic cerebral palsy (USCP). AIMS: To investigate hand use by children with USCP in daily activities of their interest. Material e methods: Sample included twenty children with USCP, aged 8 to 14 years old. Participants identified bimanual activities of their interest and no interest. Children's performance on these activities were videotaped. Videos were coded according to the affected extremity's forms and effectiveness of use, caregiver provision and types of assistance, and child's satisfaction...
February 8, 2019: Scandinavian Journal of Occupational Therapy
Yukiyo Shimizu, Hideki Kadone, Shigeki Kubota, Tomoyuki Ueno, Yoshiyuki Sankai, Yasushi Hada, Masashi Yamazaki
Cerebral palsy (CP) patients with spastic diplegia struggle to perform activities of daily life (ADL) using their upper arms. The single-joint-type Hybrid Assistive limb (HAL) for upper limbs is a new portable robot that can provide elbow motion support in accordance with bioelectric activation of patient's biceps and triceps brachii muscles. The purpose of this study is to assess the feasibility and efficacy of the use of HAL for CP patients. Two patients were enrolled in this study. (Case 1: a 19-years-old male, at the Gross Motor Function Classification System (GMFCS) level IV, Case 2: a 17-years-old male at GMFCS level III)...
2019: Frontiers in Neurology
Koen J F M Dekkers, Rob J E M Smeets, Yvonne J M Janssen-Potten, Andrew M Gordon, Lucianne A W M Speth, Eugene A A Rameckers
Background: For children with unilateral spastic cerebral palsy (USCP), reduced muscle strength may lead to activity limitations. However, despite existence of many upper limb strength measures, none measure strength in the context of functional activities in which the strength must be maintained for several seconds. Objective: The objective was to evaluate the psychometric properties of two newly developed functional hand and upper limb muscle-strength tests (Cup- and Box task) in children (7-12 years) with USCP...
February 4, 2019: Physical Therapy
Ana Paula Salazar, Aline Souza Pagnussat, Gabriela Alves Pereira, Gabriela Scopel, Janice Luisa Lukrafka
OBJECTIVE: To systematically review the effectiveness of neuromuscular electrical stimulation (NMES) as an adjuvant therapy to improve gross motor function in children with spastic cerebral palsy. METHODS: MEDLINE, EMBASE, Cochrane CENTRAL, PEDro and Scopus were searched. We included randomized controlled trials examining the effects of NMES combined with other therapies on gross motor function as assessed by the Gross Motor Function Measure (GMFM) and its functional dimensions...
January 23, 2019: Brazilian Journal of Physical Therapy
Laetitia Houx, Amandine Dubois, Sylvain Brochard, Christelle Pons
OBJECTIVE: Botulinum toxin injection (BTI) is the primary treatment for spasticity in children. Anxiety and pain are important concerns to address to attenuate the discomfort of BTI. The aim of this study was to compare the effectiveness of medical clowns and usual distractions, both added to nitrous oxide (N2 O) and analgesic cream, on pain and anxiety during BTI sessions in children. METHODS: The primary outcome was pain evaluated by the Face, Legs, Activity, Cry, Consolability (FLACC) scale...
January 29, 2019: Annals of Physical and Rehabilitation Medicine
Farah Thabet, Kalthoum Tlili-Graiess, Brahim Tabarki
No abstract text is available yet for this article.
January 31, 2019: Archives of Disease in Childhood
Alexander Springer
Cerebral palsy is a rare condition following injury of the developing brain and including nonprogressive neurological disorders, spasticity, intellectual impairment and others. Boys with cerebral palsy have a high incidence of undescended testis. Although the motives for treatment (infertility, cancer prevention, psychological aspects, testicular torsion) are not different in boys without neurological impairment, the decision-making process in boys with cerebral palsy is very difficult. Besides medical and surgical arguments the discussion involves challenging ethical issues...
February 1, 2019: Sexual Development: Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation
Ieke Anker-van der Wel, Ana R P Smorenburg, Nicole M de Roos, Olaf Verschuren
PURPOSE: Since the dose, timing and source of dietary protein intake are important for muscle growth and development, the aim of this study was to examine the dose, timing and source of protein intake of young people with cerebral palsy. MATERIALS AND METHODS: Dietary intake was assessed in 19 children with spastic cerebral palsy (Gross Motor Function Classification System levels I-V; Eating and Drinking Classification System levels I-V; 10 males, 9 females; mean [SD] age 11 years 2 months [3 years 3 months]) using a 3-day food diary...
January 29, 2019: Disability and Rehabilitation
Mariane Fernandes Ribeiro, Ana Paula Espindula, Janaine Brandão Lage, Domingos Emanuel Bevilacqua Júnior, Luanna Honorato Diniz, Ednéia Corrêa de Mello, Alex Abadio Ferreira, Mara Lúcia Fonseca Ferraz, Vicente de Paula Antunes Teixeira
OBJECTIVE: Investigation of the effects of hippotherapy treatment on lower limb muscle activity and gross motor function in subjects with cerebral palsy (CP), comparing them to a group of subjects with adequate motor development. METHODS: Evaluation was made of seven individuals with spastic diparetic CP, average age 9.3 (±3.3) years (CP group), Gross Motor Function Classification System (GMFCS) levels I and II, and eight individuals with adequate motor development, average age 10...
January 2019: Journal of Bodywork and Movement Therapies
Mathew J Wallis, Amber Boys, Elisa Tassano, Martin B Delatycki
A small heterozygous deletion involving KANK1 was originally reported in 2005 to cause cerebral palsy in one large Israeli family of Jewish Moroccan origin. There were nine affected children over two generations to five unaffected fathers. All of these children had congenital hypotonia that evolved into spastic quadriplegia over the first year of life, along with intellectual impairment and brain atrophy. The subsequent clinical depictions of other individuals with neurological disease harbouring a comparable KANK1 deletion have been extremely variable and most often quite dissimilar to the original family...
January 23, 2019: European Journal of Medical Genetics
Chan-Young Kwon, Boram Lee, Gyu Tae Chang, Sang-Hoon Yoon
BACKGROUND: In children, cerebral palsy (CP) is one of the most common causes of irreversible neurological sequelae. Acupotomy, a modernized acupuncture form combining the effects of microsurgery and conventional acupuncture, may show specific benefits in the treatment of CP, especially with respect to spasticity. The aim of this review was to evaluate the efficacy of acupotomy for CP. METHODS: Eleven databases were comprehensively searched from their inception dates to November 27, 2018...
January 2019: Medicine (Baltimore)
Carlo M Bertoncelli, Paola Altamura, Edgar Ramos Vieira, Domenico Bertoncelli, Susanne Thummler, Federico Solla
BACKGROUND: Intellectual disability and impaired adaptive functioning are common in children with cerebral palsy, but there is a lack of studies assessing these issues in teenagers with cerebral palsy. Therefore, the aim of this study was to develop and test a predictive machine learning model to identify factors associated with intellectual disability in teenagers with cerebral palsy. METHODS: This was a multicenter controlled cohort study of 91 teenagers with cerebral palsy (53 males, 38 females; mean age ± SD = 17 ± 1 y; range: 12-18 y)...
January 22, 2019: Journal of Child Neurology
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