keyword
https://read.qxmd.com/read/38537216/unusual-renal-uptake-of-131i-mibg-in-a-young-hypertensive-with-renal-artery-stenosis
#1
JOURNAL ARTICLE
Agrawal Roopal, Malhotra Gaurav
A 10-year-old hypertensive girl underwent 131I-MIBG scan to rule out neural crest derived tumor. The whole-body images revealed diffuse intense tracer uptake in the right kidney, which persisted in 96-hour images as well. CT renal angiography revealed 90% to 95% right renal artery stenosis. Thereafter, she underwent baseline and angiotensin receptor blockade renal dynamic imaging, which revealed hemodynamically significant renal artery stenosis. Pattern of diffuse and intense 131I-MIBG uptake, albeit rare, still warrants further evaluation to rule out renal artery stenosis and investigate its hemodynamic significance for appropriate management...
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537213/occult-smarca4-deficient-undifferentiated-carcinoma-unmasked-by-68ga-fapi-46-pet-ct
#2
JOURNAL ARTICLE
Weizhi Xu, Long Zhao, Jiayu Cai, Haojun Chen
SMARCA4-deficient undifferentiated tumors (SMARCA4-dUT) are rare and aggressive neoplasms commonly found in male smokers and portend a poor prognosis. In this case, we reported 18F-FDG and 68Ga-FAPI-46 PET/CT findings in an occult SMARCA4-dUT located in the left pulmonary hilum along with mediastinal lymph node metastases. 68Ga-FAPI-46 PET/CT showed superiority over 18F-FDG for detecting SMARCA4-dUT lesions. This case highlighted that 68Ga-FAPI-46 PET/CT may be a promising imaging modality in the evaluation of SMARCA4-dUT, particularly for detecting the occult SMARCA4-dUT arising in uncommon sites...
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537208/68ga-fapi-pet-ct-in-an-interesting-case-of-metastatic-pulmonary-meningioma
#3
JOURNAL ARTICLE
Priyavrat Purohit, Bhagwant Rai Mittal, Rajender Kumar, Harmandeep Singh, Jaya Shukla, Amanjit Bal, Navneet Singh
Meningiomas are one of the major primary CNS tumors. Most meningiomas are benign, but rarely, these metastasize to distant organs, the lungs being the commonest site of metastasis. 18F-FDG PET/CT has been used to evaluate metastatic pulmonary meningioma. However, 68Ga-FAPI PET/CT has not yet been evaluated. The present case highlights the 68Ga-FAPI uptake in metastatic pulmonary meningioma in a postoperated case of left tentorial meningioma presenting with lung masses. Image-guided biopsy from the lung mass was consistent with metastatic meningioma...
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537181/comparison-between-combined-ultrasounds-and-magnetic-resonance-imaging-in-the-differentiation-of-benign-and-malignant-breast-lesions-a-cross-sectional-study
#4
JOURNAL ARTICLE
Chaoxi Li, Dehui Wen, Haiyong Lu
AIM: To explore the performance of single or combined ultrasound (US) in diagnosing malignant breast lesions, and then compare the results with a magnetic resonance imaging (MRI) aspect. MATERIAL AND METHODS: Patients' demographics, tumor markers, and imaging examination were collected. Diagnostic models based on B-mode, color Doppler ultrasounds (CDU), strain elastography (SE), MRI, B-mode US + CDU, B-mode US + SE, and B-mode US + CDU + SE were developed using logistic regression analysis...
February 13, 2024: Medical Ultrasonography
https://read.qxmd.com/read/38537177/an-unexpected-seminal-vesicle-pitfall-in-psma-pet
#5
JOURNAL ARTICLE
Angela Bronte, Juan J Rosales, Marcos Torres Roca, Bernardino Miñana, Macarena Rodríguez-Fraile
A 76-year-old man undergoing hormone therapy for prostate cancer was referred for 68Ga-PSMA-11-PET (PSMA PET) due to persistently detectable PSA level. No PSMA-positive tumor lesions were detected, so a delayed phase imaging was performed, which revealed focal PSMA uptake in the right seminal vesicle together with contrast accumulation on excretory phase contrast-enhanced CT. These findings were finally determined to be secondary to urinary reflux as a consequence of a prostatic enucleation he had undergone 5 months earlier following an episode of acute urinary retention...
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537059/an-mri-radiomics-approach-to-discriminate-hemorrhage-prone-intracranial-tumors-before-stereotactic-biopsy
#6
JOURNAL ARTICLE
Yupeng Zhang, Tingliang Cao, Haoyu Zhu, Yuqi Song, Changxuan Li, Chuhan Jiang, Chao Ma
PURPOSE: To explore imaging biomarkers predictive of intratumoral hemorrhage for lesions intended for elective stereotactic biopsy. METHOD: This study included a retrospective cohort of 143 patients with 175 intracranial lesions intended for stereotactic biopsy. All the lesions were randomly split into a training dataset (n=121) and a test dataset (n=54) at a ratio of 7:3. 34 lesions were defined as "hemorrhage-prone tumors" as hemorrhage occurred between initial diagnostic MRI acquisition and the scheduled biopsy procedure...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38536982/lung-cancer-screening-in-brazil-recommendations-from-the-brazilian-society-of-thoracic-surgery-brazilian-thoracic-association-and-brazilian-college-of-radiology-and-diagnostic-imaging
#7
JOURNAL ARTICLE
Luiz Fernando Ferreira Pereira, Ricardo Sales Dos Santos, Daniel Oliveira Bonomi, Juliana Franceschini, Ilka Lopes Santoro, André Miotto, Thiago Lins Fagundes de Sousa, Rodrigo Caruso Chate, Bruno Hochhegger, Artur Gomes Neto, Airton Schneider, César Augusto de Araújo Neto, Dante Luiz Escuissato, Gustavo Faibischew Prado, Luciana Costa-Silva, Mauro Musa Zamboni, Mario Claudio Ghefter, Paulo César Rodrigues Pinto Corrêa, Pedro Paulo Teixeira E Silva Torres, Ricardo Kalaf Mussi, Valdair Francisco Muglia, Irma de Godoy, Wanderley Marques Bernardo
Although lung cancer (LC) is one of the most common and lethal tumors, only 15% of patients are diagnosed at an early stage. Smoking is still responsible for more than 85% of cases. Lung cancer screening (LCS) with low-dose CT (LDCT) reduces LC-related mortality by 20%, and that reduction reaches 38% when LCS by LDCT is combined with smoking cessation. In the last decade, a number of countries have adopted population-based LCS as a public health recommendation. Albeit still incipient, discussion on this topic in Brazil is becoming increasingly broad and necessary...
2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536925/virtual-formalin-fixed-and-paraffin-embedded-staining-of-fresh-brain-tissue-via-stimulated-raman-cyclegan-model
#8
JOURNAL ARTICLE
Zhijie Liu, Lingchao Chen, Haixia Cheng, Jianpeng Ao, Ji Xiong, Xing Liu, Yaxin Chen, Ying Mao, Minbiao Ji
Intraoperative histology is essential for surgical guidance and decision-making. However, frozen-sectioned hematoxylin and eosin (H&E) staining suffers from degraded accuracy, whereas the gold-standard formalin-fixed and paraffin-embedded (FFPE) H&E is too lengthy for intraoperative use. Stimulated Raman scattering (SRS) microscopy has shown rapid histology of brain tissue with lipid/protein contrast but is challenging to yield images identical to nucleic acid-/protein-based FFPE stains interpretable to pathologists...
March 29, 2024: Science Advances
https://read.qxmd.com/read/38536643/a-systematic-review-of-machine-learning-based-thyroid-tumor-characterisation-using-ultrasonographic-images
#9
REVIEW
Niranjan Yadav, Rajeshwar Dass, Jitendra Virmani
Ultrasonography is widely used to screen thyroid tumors because it is safe, easy to use, and low-cost. However, it is simultaneously affected by speckle noise and other artifacts, so early detection of thyroid abnormalities becomes difficult for the radiologist. Therefore, various researchers continuously address the limitations of sonography and improve the diagnosis potential of US images for thyroid tissue from the last three decays. Accordingly, the present study extensively reviewed various CAD systems used to classify thyroid tumor US (TTUS) images related to datasets, despeckling algorithms, segmentation algorithms, feature extraction and selection, assessment parameters, and classification algorithms...
March 27, 2024: Journal of Ultrasound
https://read.qxmd.com/read/38536602/endoscopic-loco-regional-treatment-in-controlling-pancreatic-neuroendocrine-tumors-pnets-behavior-a-case-series-and-literature-review
#10
JOURNAL ARTICLE
Cosmas Rinaldi Adithya Lesmana
Pancreatic neuroendocrine tumors (PNETs) are considered rare pancreatic neoplasms, and it is a challenging disease entity due to its indolent behavior and is difficult to manage. Diagnostic challenge is usually found in the imaging-based approach, such as transabdominal ultrasound, abdominal CT scan, and abdominal MRI. Surgery is still the main key player in controlling the disease. The main problems in clinical practice are the early detection of small PNETs lesion and non-functional PNET (NF-PNET) cases. Most cases usually come with large tumor size or metastatic disease...
March 27, 2024: Clinical Journal of Gastroenterology
https://read.qxmd.com/read/38536542/multiparametric-mri-based-intratumoral-and-peritumoral-radiomics-for-predicting-the-pathological-differentiation-of-hepatocellular-carcinoma
#11
JOURNAL ARTICLE
Hai-Feng Liu, Min Wang, Qing Wang, Yang Lu, Yu-Jie Lu, Ye Sheng, Fei Xing, Ji-Lei Zhang, Sheng-Nan Yu, Wei Xing
PURPOSE: To explore the predictive potential of intratumoral and multiregion peritumoral radiomics features extracted from multiparametric MRI for predicting pathological differentiation in hepatocellular carcinoma (HCC) patients. METHODS: A total of 265 patients with 277 HCCs (training cohort n = 193, validation cohort n = 84) who underwent preoperative MRI were retrospectively analyzed. The risk factors identified through stepwise regression analysis were utilized to construct a clinical model...
March 27, 2024: Insights Into Imaging
https://read.qxmd.com/read/38536511/repeatability-of-18-f-fdg-uptake-in-metastatic-bone-lesions-of-breast-cancer-patients-and-implications-for-accrual-to-clinical-trials
#12
JOURNAL ARTICLE
Mark Muzi, Lanell M Peterson, Jennifer M Specht, Daniel S Hippe, Alena Novakova-Jiresova, Jean H Lee, Brenda F Kurland, David A Mankoff, Nancy Obuchowski, Hannah M Linden, Paul E Kinahan
BACKGROUND: Standard measures of response such as Response Evaluation Criteria in Solid Tumors are ineffective for bone lesions, often making breast cancer patients that have bone-dominant metastases ineligible for clinical trials with potentially helpful therapies. In this study we prospectively evaluated the test-retest uptake variability of 2-deoxy-2-[18F]fluoro-D-glucose (18 F-FDG) in a cohort of breast cancer patients with bone-dominant metastases to determine response criteria. The thresholds for 95% specificity of change versus no-change were then applied to a second cohort of breast cancer patients with bone-dominant metastases...
March 27, 2024: EJNMMI Research
https://read.qxmd.com/read/38536464/automated-graded-prognostic-assessment-for-patients-with-hepatocellular-carcinoma-using-machine-learning
#13
JOURNAL ARTICLE
Moritz Gross, Stefan P Haider, Tal Ze'evi, Steffen Huber, Sandeep Arora, Ahmet S Kucukkaya, Simon Iseke, Bernhard Gebauer, Florian Fleckenstein, Marc Dewey, Ariel Jaffe, Mario Strazzabosco, Julius Chapiro, John A Onofrey
BACKGROUND: Accurate mortality risk quantification is crucial for the management of hepatocellular carcinoma (HCC); however, most scoring systems are subjective. PURPOSE: To develop and independently validate a machine learning mortality risk quantification method for HCC patients using standard-of-care clinical data and liver radiomics on baseline magnetic resonance imaging (MRI). METHODS: This retrospective study included all patients with multiphasic contrast-enhanced MRI at the time of diagnosis treated at our institution...
March 27, 2024: European Radiology
https://read.qxmd.com/read/38536460/prediction-of-tumor-recurrence-after-surgical-resection-of-ampullary-adenocarcinoma-using-magnetic-resonance-imaging
#14
JOURNAL ARTICLE
Sunyoung Lee, Ji Eun Lee, Kyeong Deok Kim, Jeong Ah Hwang, Seo-Youn Choi, Ji Eun Moon, Myeong-Jin Kim
OBJECTIVES: To predict tumor recurrence in patients who underwent surgical resection of ampullary adenocarcinoma using preoperative magnetic resonance (MR) imaging findings combined with clinical findings. METHODS: In this multicenter study, a total of 113 patients (mean age, 62.9 ± 9.8 years; 58 men and 55 women) with ampullary adenocarcinoma who underwent preoperative MR imaging and surgery with margin-negative resection between 2006 and 2017 were retrospectively included...
March 27, 2024: European Radiology
https://read.qxmd.com/read/38536425/integrated-pretreatment-diffusion-kurtosis-imaging-and-serum-squamous-cell-carcinoma-antigen-levels-a-biomarker-strategy-for-early-assessment-of-radiotherapy-outcomes-in-cervical-cancer
#15
JOURNAL ARTICLE
Xiang Zheng, Fangmin Shen, Wenjuan Chen, Wang Ren, Shaoliang Tang
OBJECTIVE: This study aims to explore the utility of pretreatment DKI parameters and serum SCC-Ag in evaluating the early therapeutic response of cervical cancer to radiotherapy. MATERIALS AND METHODS: A total of 33 patients diagnosed with cervical cancer, including 31 cases of cervical squamous cell carcinoma and two cases of adenosquamous carcinoma, participated in the study. All patients underwent conventional MRI and DKI scans on a 3T magnetic resonance scanner before radiotherapy and after ten sessions of radiotherapy...
March 27, 2024: Abdominal Radiology
https://read.qxmd.com/read/38536107/benchmarking-machine-learning-based-real-time-respiratory-signal-predictors-in-4d-sbrt
#16
JOURNAL ARTICLE
Lukas Wimmert, Maximilian Nielsen, Frederic Madesta, Tobias Gauer, Christian Hofmann, Rene Werner
BACKGROUND: Stereotactic body radiotherapy of thoracic and abdominal tumors has to account for respiratory intrafractional tumor motion. Commonly, an external breathing signal is continuously acquired that serves as a surrogate of the tumor motion and forms the basis of strategies like breathing-guided imaging and gated dose delivery. However, due to inherent system latencies, there exists a temporal lag between the acquired respiratory signal and the system response. Respiratory signal prediction models aim to compensate for the time delays and to improve imaging and dose delivery...
March 27, 2024: Medical Physics
https://read.qxmd.com/read/38535775/the-utility-of-spectroscopic-mri-in-stereotactic-biopsy-and-radiotherapy-guidance-in-newly-diagnosed-glioblastoma
#17
JOURNAL ARTICLE
Abinand C Rejimon, Karthik K Ramesh, Anuradha G Trivedi, Vicki Huang, Eduard Schreibmann, Brent D Weinberg, Lawrence R Kleinberg, Hui-Kuo G Shu, Hyunsuk Shim, Jeffrey J Olson
Current diagnostic and therapeutic approaches for gliomas have limitations hindering survival outcomes. We propose spectroscopic magnetic resonance imaging as an adjunct to standard MRI to bridge these gaps. Spectroscopic MRI is a volumetric MRI technique capable of identifying tumor infiltration based on its elevated choline (Cho) and decreased N-acetylaspartate (NAA). We present the clinical translatability of spectroscopic imaging with a Cho/NAA ≥ 5x threshold for delineating a biopsy target in a patient diagnosed with non-enhancing glioma...
March 20, 2024: Tomography: a Journal for Imaging Research
https://read.qxmd.com/read/38535772/musculoskeletal-pitfalls-on-molecular-imaging-studies-of-oncologic-patients-how-to-stay-out-of-trouble
#18
REVIEW
Brooke Sarna, Ty Subhawong, Efrosyni Sfakianaki, Richard Wang, Anna Christodoulou-Vega, Fabiano N Cardoso
An increasing amount of molecular imaging studies are ordered each year for an oncologic population that continues to expand and increase in age. The importance of these studies in dictating further care for oncologic patients underscores the necessity of differentiating benign from malignant findings, particularly for a population in whom incidental findings are common. The aim of this review is to provide pictorial examples of benign musculoskeletal pathologies which may be found on molecular imaging and which may be mistaken for malignant processes...
March 8, 2024: Tomography: a Journal for Imaging Research
https://read.qxmd.com/read/38535766/dual-energy-ct-in-oncologic-imaging
#19
REVIEW
Giovanni Foti, Giorgio Ascenti, Andrea Agostini, Chiara Longo, Fabio Lombardo, Alessandro Inno, Alessandra Modena, Stefania Gori
Dual-energy CT (DECT) is an innovative technology that is increasingly widespread in clinical practice. DECT allows for tissue characterization beyond that of conventional CT as imaging is performed using different energy spectra that can help differentiate tissues based on their specific attenuation properties at different X-ray energies. The most employed post-processing applications of DECT include virtual monoenergetic images (VMIs), iodine density maps, virtual non-contrast images (VNC), and virtual non-calcium (VNCa) for bone marrow edema (BME) detection...
February 23, 2024: Tomography: a Journal for Imaging Research
https://read.qxmd.com/read/38535492/iron-oxide-magnetite-based-nanobiomaterial-with-medical-applications-environmental-hazard-assessment-using-terrestrial-model-species
#20
JOURNAL ARTICLE
Susana I L Gomes, Janeck J Scott-Fordsmand, Mónica J B Amorim
Nanobiomaterials (NBMs) have tremendous potential applications including in cancer diagnosis and treatment. However, the health and environmental effects of NBMs must be thoroughly assessed to ensure safety. Fe3 O4 (magnetite) nanoparticles coated with polyethylene glycol (PEG) and poly (lactic-co-glycolic acid) (PLGA) were one of the focus NBMs within the EU project BIORIMA. Fe3 O4 PEG-PLGA has been proposed to be used as a contrast agent in magnetic resonance imaging for the identification of solid tumors and has revealed low cytotoxicity in several cell lines...
February 22, 2024: Journal of Xenobiotics
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