Sergiu Groppa, Gabriel Gonzalez-Escamilla, Gerd Tinkhauser, Halim Ibrahim Baqapuri, Bastian Sajonz, Christoph Wiest, Joana Pereira, Damian M Herz, Matthias R Dold, Manuel Bange, Dumitru Ciolac, Viviane Almeida, John Neuber, Daniela Mirzac, Juan Francisco Martín-Rodríguez, Christian Dresel, Muthuraman Muthuraman, Astrid D Adarmes Gomez, Marta Navas, Gizem Temiz, Aysegul Gunduz, Lilia Rotaru, Yaroslav Winter, Rick Schuurman, Maria F Contarino, Martin Glaser, Michael Tangermann, Albert F G Leentjens, Pablo Mir, Cristina V Torres Diaz, Carine Karachi, David E J Linden, Huiling Tan, Volker A Coenen
BACKGROUND: Deep brain stimulation (DBS) is a highly efficient, evidence-based therapy to alleviate symptoms and improve quality of life in movement disorders such as Parkinson's disease, essential tremor, and dystonia, which is also being applied in several psychiatric disorders, such as obsessive-compulsive disorder and depression, when they are otherwise resistant to therapy. SUMMARY: At present, DBS is clinically applied in the so-called open-loop approach, with fixed stimulation parameters, irrespective of the patients' clinical state(s)...
2024: Stereotactic and Functional Neurosurgery