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Po-Chun Chen, Wei-Yu Kao, Yuan-Lung Cheng, Yuan-Jen Wang, Ming-Chih Hou, Jaw-Ching Wu, Chien-Wei Su
BACKGROUND/PURPOSE: The impact of non-alcoholic fatty liver disease (NAFLD) on the prevalence of chronic kidney disease (CKD) is not fully elucidated. We aimed to assess the correlation between NAFLD and CKD in a large population study. METHODS: We included consecutive subjects who had received health check-up service at Taipei Veterans General Hospital from 2002 to 2009. NAFLD was diagnosed with abdominal ultrasound, and advanced liver fibrosis was determined with NAFLD fibrosis score (NAFLD-FS)...
March 12, 2019: Journal of the Formosan Medical Association
Chen-Ta Chi, Gar-Yang Chau, Rheun-Chuan Lee, Yen-Ying Chen, Hao-Jan Lei, Ming-Chih Hou, Yee Chao, Yi-Hsiang Huang
BACKGROUND/PURPOSE: Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare primary liver cancer. Preoperative diagnosis of cHCC-CCA is difficult, and outcome of cHCC-CCA is obscured. Our study aimed to investigate the clinicopathological and radiological features of cHCC-CCA and compare their outcomes with hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). METHODS: From August 2010 to December 2017, 891 patients undergoing liver tumor resection in Taipei Veterans General Hospital, including 30 patients with pathology-proven cHCC-CCA, 819 HCC, and 42 ICC were retrospectively reviewed...
March 12, 2019: Journal of the Formosan Medical Association, Taiwan Yi Zhi
Nien-Tzu Chang, Ta-Chen Su
BACKGROUND AND AIMS: Inherited familial hypercholesterolemia (FH) increases cardiovascular risks, but perceived depression in FH is unknown. This study aims to explore the association between the FH and perceived depression. METHODS: This study was a hospital-based design, we started to recruit clinical diagnosis of phenotypic FH since 2014 for the Ten Countries Study in the Asia-Pacific region. We consecutively recruited 302 FH patients and other 414 comparison subjects (214 subjects with hypertriglyceridemia and 200 subjects with normal lipid controls) from the special lipid clinic of National Taiwan University Hospital, Taipei...
March 2019: Atherosclerosis. Supplements
Chun-Yuh Yang, Yi-Hao Weng, Ya-Wen Chiu
Several studies suggested short-term exposure to air pollution might be associated with suicide mortality, although results have been inconsistent and vary depending upon the type of air contaminants. While seasonal variation associated with suicide was reported to occur and that in the spring and early summer there are peaks in ozone (O3 ) distribution, the relationship between these two parameters is not known. The aim of this study was to examine the potential association between O3 levels and daily mortality rate related to suicide in Taipei for the period 2004-2008 using a time-stratified case-crossover analysis...
March 14, 2019: Journal of Toxicology and Environmental Health. Part A
Yen-Cheng Shih, Shih-Pin Chen, Jong-Ling Fuh, Yen-Feng Wang, Shuu-Jiun Wang
BACKGROUND: Cold weather is reportedly a precipitator of reversible cerebral vasoconstriction syndrome (RCVS) in a few cases. We systematically investigated whether meteorological factors correlate with the occurrence of RCVS. METHODS: We conducted a retrospective analysis of a cohort of patients diagnosed with RCVS or probable RCVS, based on International Classification of Headache Disorders, third edition (ICHD-3) criteria, in a hospital-based headache center from March 2005 to February 2014...
March 13, 2019: Headache
Y Z Shi, S Xiong, Y Zhang, L K Chin, Y-Y Chen, J B Zhang, T H Zhang, W Ser, A Larsson, S H Lim, J H Wu, T N Chen, Z C Yang, Y L Hao, B Liedberg, P H Yap, K Wang, D P Tsai, C-W Qiu, A Q Liu
The original version of this Article omitted the author Kuan Wang, who is from the 'College of Biomedical Engineering, Taipei Medical University, Taipei 11031, Taiwan' and 'Nanyang Environment & Water Research Institute, Nanyang Technological University, Singapore 637141, Singapore.'Also, the author S.H. Lim was incorrectly given as L.S. Hoi and A. Larsson was incorrectly given as A. Larson.The "Author contributions" was amended to reflect the authorship changes. It previously read 'Y.Z.S., C...
March 12, 2019: Nature Communications
Shih-Hui Chen, Hsiang-Ru Lai, Su-Ru Chen, Pi-Chu Lin, Kuei-Ru Chou, Pi-Hsia Lee
BACKGROUND: Single- and five-item measures have been used prevalently to assess exercise stages of change. Few studies have investigated the development of instruments that are able to continuously measure exercise stages of change and have conducted associated psychometric analyses. PURPOSE: This study aimed to translate the original, English-language version of the University of Rhode Island Change Assessment-Exercise 2 (URICA-E2), a continuous exercise stages of change assessment instrument, into Chinese and then to test the validity and reliability of the translated version...
March 7, 2019: Journal of Nursing Research: JNR
Yu-Lun Hsu, Chun-Chi Lin, Jeng-Kai Jiang, Hung-Hsin Lin, Yuan-Tzu Lan, Huann-Sheng Wang, Shung-Haur Yang, Wei-Shone Chen, Tzu-Chen Lin, Jen-Kou Lin, Pei-Ching Lin, Shih-Ching Chang
PURPOSE: The incidence, pathogenesis, molecular pathways, and outcomes of colorectal cancer vary depending on the location of the tumor. This study aimed to compare the difference in tumor characteristics and the outcome between right-sided colon cancer and left-sided colorectal cancer (LCRC). MATERIALS AND METHODS: A total of 1503 patients with colorectal cancer who underwent surgery at the Taipei Veterans General Hospital between 2000 and 2010 were enrolled in this study...
March 10, 2019: International Journal of Biological Markers
M Remzi Karaoğuz, Ece Yurtseven, Gamze Aslan, Bilgen Gülşen Deliormanlı, Ömer Adıgüzel, Mehmet Gönen, Ko-Mai Li, Elif Nur Yılmaz
BACKGROUND: Short and long ambulatory electrocardiographic monitoring with different systems is a widely used method to detect cardiac arrhythmias. In this study, we aimed to evaluate the effectiveness of a novel monitoring device on cardiac arrhythmia detection. METHODS: We used two different protocols to evaluate device performance. For the first one, 36 healthy subjects were enrolled. The standard 12‑lead, 24-h Holter monitoring and the novel single lead electrocardiogram (ECG) Patch Monitor (EPM) device (BeyondCare®, Rooti Labs Ltd...
February 28, 2019: Journal of Electrocardiology
Fu-Wei Su, Chien-Kun Ting, Jing-Yang Liou, Yi-Chang Chen, Mei-Yung Tsou, Shen-Chih Wang
Response surface models (RSMs) were used to predict effects of multiple drugs interactions. Our study was aimed to validate accuracy of the previous published volunteer models during transoesophageal echocardiography (TEE). This is a cross-sectional study with 20 patients scheduled for transesophageal echocardiography in Taipei Veterans General Hospital, Taiwan. Effect-site concentration pairs of alfentanil and propofol were recorded and converted to equivalent remifentanil and propofol effect-site concentrations...
March 7, 2019: Scientific Reports
Yi-Min Li, Henry Hsin-Chung Lee, Yu-Ling Lo, Hui-Lin Chao
PURPOSE: The purpose of this study was to evaluate content validity and feasibility of the Chinese language perineal assessment tool (PAT-C), to assess its use in the clinical setting, and establish an optimal cut point for identifying patients at high risk for incontinence-associated dermatitis (IAD). DESIGN: Psychometric evaluation of existing instrument. SUBJECTS AND SETTING: The sample comprised 440 patients managed in intensive care units of 3 hospitals across the island of Taiwan and an affiliated home care service...
March 2019: Journal of Wound, Ostomy, and Continence Nursing
Po-Chun Chen, Nai-Chi Chiu, Chien-Wei Su, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin, Jaw-Ching Wu
BACKGROUND: To assess long-term prognoses of patients with solitary hepatocellular carcinoma (HCC) < 2 cm (the Barcelona Clinic Liver Cancer, BCLC stage 0) after radiofrequency ablation (RFA). METHODS: We retrospectively enrolled 271 patients with BCLC stage 0 HCC who had undergone RFA at Taipei Veterans General Hospital from 2002 to 2016. Factors determining poor overall survival (OS) and recurrence after RFA were analyzed by Cox proportional hazards model...
January 2019: Journal of the Chinese Medical Association: JCMA
Hailong Huang, Liangpu Xu, Meihuan Chen, Na Lin, Huili Xue, Lingji Chen, Yan Wang, Deqin He, Min Zhang, Yuan Lin
Thalassemia and hemoglobinopathy are two common inherited disorders, which are highly prevalent in southern China. However, there is little knowledge on the genotypes of thalassemia and hemoglobinopathy in Southeastern China. In this study, we present a large-scale genetic detection and molecular characterization of thalassemia and hemoglobinopathy in Fujian province, Southeastern China. A total of 189414 subjects screened for thalassemia were recruited, and the hemoglobin components and levels were investigated...
March 5, 2019: Scientific Reports
Lin-Jye Huang, Fu-Chang Hu, Chinyu Wu, Yi-Hong Yang, Shu-Chun Lee, Yung-Chun Fang, Hsu-Chang Huang, Kuan-Yu Lai, Chun-Yi Yu
INTRODUCTION: The 36-item Dispositional Flow Scale-2 (DFS-2) and Flow State Scale-2 (FSS-2) were developed to assess flow experience in daily and specific activities. Although their validity and reliability had been examined in general populations and different cultures, little is known for schizophrenic subjects. Thus, this study aimed to validate Traditional-Chinese DFS-2 (TCDFS-2) and FSS-2 (TCFSS-2) in Taiwanese subjects with schizophrenia or schizoaffective disorder. METHODS: We recruited 229 adult participants from outpatient clinics, day care centers, and psychiatric rehabilitation centers in Taipei...
December 19, 2018: Psychiatry Research
Tzu-Jung Tseng, Yi-Syuan Wu, Jia-Hong Tang, Yen-Hui Chiu, Yu-Ting Lee, I-Chun Fan, Ta-Chien Chan
BACKGROUND: According to a WHO report, nearly 15% of adults aged 60 and over suffer from a mental disorder, constituting 6.6% of the total disability for this age group. Taipei City faces rapid transformation towards an aging society, with the proportion of elderly in the total population rising from 12% in 2008 to 16% in 2016. The aim of this study is to identify the prevalence of mental disorders among the elderly in Taipei City and to elucidate risk factors contributing to mental disorders...
February 28, 2019: BMC Geriatrics
Tony Szu-Hsien Lee, Wen-Chii Tzeng, Hui-Hsun Chiang
OBJECTIVES: To examine the mechanisms of coping strategies on nurses' psychological well-being, practice environments and safety attitudes. METHODS: A cross-sectional study design was used. Structural equation modeling was performed to analyze the results. Five hundred clinical nurses were randomly selected from a large group of 1,500 from a medical center with 1,350 beds in Taipei, Taiwan, from July to October 2015. Self-report questionnaires were administered to measure coping strategies (Brief COPE), psychological well-being (Ryff's Psychological Well-being Scale), nurses' practice environments (Practice Environment Scale of the Nursing Work Index), and safety attitudes (Safety Attitudes Questionnaire)...
February 25, 2019: Journal of Nursing Scholarship
Lamtiur Junita Bancin, Bruno A Walther, Yao-Chang Lee, Alexander Kunz
Environmental pollution with plastic is a growing problem worldwide. This study investigates the microplastic and mesoplastic pollution of Xialiao Beach in northern Taiwan. Sand from the surface (1 cm depth) was collected in a systematic manner. A total of 80 samples were taken along four transects, and plastic particles (≥1 mm) were extracted and quantified. In total, 1939 microplastic particles were recovered, with an average of 96.8 particles per 1 m2 . Statistical analysis showed that the backshore had significantly more microplastic particles than the supra littoral or intertidal...
March 2019: Marine Pollution Bulletin
Yu-Chun Chen, Wen-Kuang Yu, Hsin-Kuo Ko, Sheng-Wei Pan, Yen-Wen Chen, Li-Ing Ho, Mauo-Ying Bien, Jia-Horng Wang, Yu-Jiun Chan, Yu Ru Kou
AIM: The older adult population is continuously growing worldwide and there is increasing use of medical recourse in older patients, especially for those requiring intensive care unit (ICU) care and mechanical ventilation (MV). The present study aimed to investigate the burden and predictors of post-ICU respiratory failure in older ICU patients weaned from MV. METHODS: In the present retrospective study, older ICU patients aged ≥60 years, who were successfully weaned from MV and discharged to the general ward from the ICU of Taipei Veterans General Hospital, Taipei, Taiwan, in 2011, were included...
February 20, 2019: Geriatrics & Gerontology International
Yu-Chen Tseng, Bao-Chung Chen, Chun-Ting Chen, Yu-Ching Chou, Niann-Tzyy Dai, Peng-Jen Chen, Tien-Yu Huang, Yu-Lueng Shih, Wei-Kuo Chang, Tsai-Yuan Hsieh, Jung-Chun Lin
Early initiation of enteral nutrition improves clinical outcomes in critical patients with serious burns. Post-pyloric tube feeding is a valuable therapeutic option for severely burned patients with poor gastric emptying. How early post-pyloric feeding can be initiated to provide more benefits to patients has not yet been examined. A fire erupted at a recreational water park in New Taipei City, Taiwan, on June 27, 2015. The results of early initiation versus delayed post-pyloric feeding in severely burned patients in this mass-casualty incident were compared...
2019: Tohoku Journal of Experimental Medicine
Amzad H Laskar, Li-Ching Lin, Xun Jiang, Mao-Chang Liang
To assess sources and processes that affect the variability of CO2 at local to regional scales, we have analyzed the mixing ratio [CO2 ] and stable isotopic compositions (δ13 C and δ18 O) of atmospheric CO2 for three years (2014-2016) in urban and sub-urban areas in Taipei, Taiwan. The data are compared with those from some background sites, viz., Lulin, Mauna Loa, and Minamitorishima, to evaluate how local emissions affect CO2 level regionally. [CO2 ] over the urban and sub-urban stations are significantly higher than that observed at the three aforementioned remote sites mainly due to local emissions, which partly mask the seasonal cycle caused by photosynthesis and respiration...
November 2018: Earth and Space Science (Hoboken, N.J.)
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