keyword
https://read.qxmd.com/read/37406996/decompressive-laminectomy-with-vertebral-stabilization-allows-neurologic-improvement-of-most-pekingese-dogs-with-thoracolumbar-vertebral-instability
#21
JOURNAL ARTICLE
Takeshi Aikawa, Yuta Miyazaki, Syuya Kihara, Masaaki Nishimura
OBJECTIVE: To describe the diagnostic findings, surgical techniques, and outcomes of thoracolumbar vertebral instability associated with or without articular process (AP) anomalies in Pekingese dogs. ANIMALS: 11 client-owned Pekingese dogs. PROCEDURES: Medical records (2007 to 2022) were reviewed. Inclusion criteria were Pekingese dogs with thoracolumbar vertebral instability that underwent decompressive laminectomy and vertebral stabilization...
July 5, 2023: Journal of the American Veterinary Medical Association
https://read.qxmd.com/read/37354389/direct-withdrawal-of-a-retained-foreign-body-bisecting-the-thoracic-spinal-canal-in-a-neurologically-intact-pediatric-patient-illustrative-case
#22
JOURNAL ARTICLE
David R Peters, Trent VanHorn, Brandon Karimian, Benjamin Pruden, Scott D Wait, Roy T Daniel, Constantin Tuleasca
BACKGROUND: Nonmissile penetrating spinal cord injury (NMPSCI) with a retained foreign body (RFB) is rare and usually results in permanent neurological deficits. In extremely rare cases, patients can present without significant neurological deficits despite an RFB that traverses the spinal canal. Given the rarity of these cases, a consensus has not yet been reached on optimal management. In a patient with an RFB and a neurologically normal clinical examination, the risk of open surgical exploration may outweigh the benefit and direct withdrawal may be a better option...
June 19, 2023: J Neurosurg Case Lessons
https://read.qxmd.com/read/37354308/the-role-of-manual-therapies-in-the-treatment-of-headache-disorders
#23
REVIEW
Sheena Pillai, Niushen Zhang
PURPOSE OF REVIEW: A comprehensive headache treatment plan typically requires both medication and non-medication treatment strategies. Manual therapies offer another therapeutic approach to headache treatment. This article reviews the evidence for manual therapies in the treatment of headache disorders. RECENT FINDINGS: Current evidence shows potential benefit from myofascial trigger point injections, myofascial release, and massage for the treatment of various headache types...
June 24, 2023: Current Neurology and Neuroscience Reports
https://read.qxmd.com/read/37346242/the-neurophysiological-lesion-a-scoping-review
#24
REVIEW
David N Taylor
OBJECTIVE: The purpose of this study was to examine the extent of the literature on the neurophysiological lesion as referenced in functional neurology. METHODS: A literature search was performed within the period from 2010 to March 2021. Search terms included central sensitization, central sensitivity syndrome, nociplastic pain, cold hyperalgesia, heat hyperalgesia, mechanical hyperalgesia, dynamic mechanical allodynia, temporal summation, spatial summation, and descending inhibition...
June 2023: Journal of Chiropractic Medicine
https://read.qxmd.com/read/37344113/spontaneous-spinal-cord-infarctions-a-systematic-review-and-pooled-analysis-protocol
#25
JOURNAL ARTICLE
Victor Gabriel El-Hajj, Vasilios Stenimahitis, Maria Gharios, Omar Ali Mahdi, Adrian Elmi-Terander, Erik Edström
INTRODUCTION: Spinal cord infarction (SCInf) is a rare ischaemic event that manifests with acute neurological deficits. It is typically classified as either spontaneous, defined as SCInf without any inciting event, or periprocedural, which typically occur in conjunction with vascular surgery with aortic manipulations. While periprocedural SCInf has recently been the subject of intensified research, especially focusing on the primary prevention of this complication, spontaneous SCInf remains less studied...
June 21, 2023: BMJ Open
https://read.qxmd.com/read/37301560/review-of-effects-of-spinal-manipulative-therapy-on-neurological-symptoms
#26
REVIEW
A Kushnir, B Fedchyshyn, O Kachmar
BACKGROUND: Neurological disorders are the leading cause of disability in the world. Neurological symptoms significantly affect the well-being of the individual. Spinal manipulative therapy (SMT) is a complementary method often used for people with neurological disorders. OBJECTIVE: This study aimed to review the existing literature on the effects of SMT on common clinical symptoms of neurologic disorders and the quality of life. METHODS: Narrative review was conducted through the literature published between January 2000 and April 2020 in English...
April 2023: Journal of Bodywork and Movement Therapies
https://read.qxmd.com/read/37211740/-monitoring-for-spine-and-spinal-cord-surgery
#27
JOURNAL ARTICLE
Aya Hashimoto, Keiko Nakahara, Gohsuke Hattori, Motohiro Morioka
Injuries of the spine and nerve root may occur during spine or spinal cord surgery, which can induce serious neurological deficits. Intraoperative monitoring plays important roles in monitoring the nerve function in various surgical manipulations, such as surgical positioning, mechanical compression, and tumor removal. This monitoring issues a warning to neuronal injuries at an early stage, and surgeons are able to prevent postoperative complications. The appropriate monitoring systems should be chosen with compatibility to the disease, surgical procedure, and lesion localization...
May 2023: No Shinkei Geka. Neurological Surgery
https://read.qxmd.com/read/37193985/manipulating-facial-musculature-with-functional-electrical-stimulation-as-an-intervention-for-major-depressive-disorder-a-focused-search-of-literature-for-a-proposal
#28
REVIEW
Ilya Demchenko, Naaz Desai, Stephanie N Iwasa, Fatemeh Gholamali Nezhad, José Zariffa, Sidney H Kennedy, Nicholas O Rule, Jeffrey F Cohn, Milos R Popovic, Benoit H Mulsant, Venkat Bhat
BACKGROUND: Major Depressive Disorder (MDD) is associated with interoceptive deficits expressed throughout the body, particularly the facial musculature. According to the facial feedback hypothesis, afferent feedback from the facial muscles suffices to alter the emotional experience. Thus, manipulating the facial muscles could provide a new "mind-body" intervention for MDD. This article provides a conceptual overview of functional electrical stimulation (FES), a novel neuromodulation-based treatment modality that can be potentially used in the treatment of disorders of disrupted brain connectivity, such as MDD...
May 16, 2023: Journal of Neuroengineering and Rehabilitation
https://read.qxmd.com/read/37020712/cervicogenic-dizziness-after-self-manipulation-of-the-cervical-spine
#29
Eric Chun-Pu Chu, Andy Fu Chieh Lin, Gordon Cheung, Kevin Hsu Kai Huang
Patients with pre-existing cervical pathologies who experience dizziness and related neck pain are referred to as having cervicogenic dizziness. We describe a case of a 49-year-old female who presented with acute onset of vertigo and imbalance following self-manipulation of the cervical spine. Examination revealed a restricted cervical range of motion, muscle hypertonicity, and positive neurological signs. Radiographs demonstrated loss of normal cervical lordosis. The patient was diagnosed with cervicogenic dizziness and prescribed chiropractic treatments that included spinal manipulation, soft tissue release, and rehabilitative exercises...
April 2023: Curēus
https://read.qxmd.com/read/37016861/biportal-endoscopic-posterior-thoracic-laminectomy-for-thoracic-spondylotic-myelopathy-caused-by-ossification-of-the-ligamentum-flavum-technical-developments-and-outcomes
#30
JOURNAL ARTICLE
Ji Yeon Kim, Ji Soo Ha, Chang Kyu Lee, Dong Chan Lee, Hyun Jin Hong, Su Yong Choi, Choon Keun Park
OBJECTIVE: Advanced biportal endoscopic surgery techniques can be used to treat thoracic myelopathy secondary to ossification of the ligamentum flavum (OLF). This case series elaborates on a feasible biportal endoscopic technique for thoracic OLF removal and evaluates clinical and radiological outcomes. METHODS: A biportal endoscopic posterior thoracic laminectomy was performed to remove the thoracic OLF. Surgical techniques have evolved from inside-out piecemeal removal methods to outside-in en bloc removal methods...
March 2023: Neurospine
https://read.qxmd.com/read/36901634/changes-in-gut-microbiota-and-multiple-sclerosis-a-systematic-review
#31
REVIEW
Alba Ordoñez-Rodriguez, Pablo Roman, Lola Rueda-Ruzafa, Ana Campos-Rios, Diana Cardona
INTRODUCTION: Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease mediated by autoimmune reactions against myelin proteins and gangliosides in the grey and white matter of the brain and spinal cord. It is considered one of the most common neurological diseases of non-traumatic origin in young people, especially in women. Recent studies point to a possible association between MS and gut microbiota. Intestinal dysbiosis has been observed, as well as an alteration of short-chain fatty acid-producing bacteria, although clinical data remain scarce and inconclusive...
March 6, 2023: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/36891015/improvement-of-chronic-neck-pain-after-posterior-atlantoaxial-surgical-fusion-via-multimodal-chiropractic-care-a-case-report
#32
Eric Chun-Pu Chu, Robert J Trager, Cliff Tao
There is a lack of research regarding the effectiveness and safety of manual therapies, including spinal manipulative therapy (SMT), for patients with previous cervical spine surgery. A 66-year-old, otherwise healthy, woman who underwent C1/2 posterior surgical fusion for rotatory instability during adolescence presented to a chiropractor with a six-month history of progressive worsening of chronic neck pain and headaches despite acetaminophen, tramadol, and physical therapy. Upon examination, the chiropractor noted postural changes, limited cervical range of motion, and muscle hypertonicity...
February 2023: Curēus
https://read.qxmd.com/read/36625030/a-critical-brainstem-relay-for-mediation-of-diffuse-noxious-inhibitory-controls
#33
JOURNAL ARTICLE
Mateusz W Kucharczyk, Francesca Di Domenico, Kirsty Bannister
The central nervous system houses naturally occurring pathways that project from the brain to modulate spinal neuronal activity. The noradrenergic locus coeruleus (the A6 nucleus) originates such a descending control whose influence on pain modulation encompasses an interaction with a spinally projecting non-cerulean noradrenergic cell group. Hypothesising the origin of an endogenous pain inhibitory pathway, our aim was to identify this cell group. A5 and A7 noradrenergic nuclei also spinally project. We probed their activity utilising an array of optogenetic manipulation techniques during in vivo electrophysiological experimentation...
January 10, 2023: Brain
https://read.qxmd.com/read/36578026/an-exploratory-study-to-understand-how-people-use-twitter-to-share-experiences-or-information-about-spinal-stenosis
#34
JOURNAL ARTICLE
Lillian L C Li, Arnold Y L Wong, Gregory N Kawchuk
BACKGROUND: Spinal stenosis is a narrowing of the spinal canal that may compress neurological tissues resulting in pain and disability. Although previous qualitative studies have solicited data regarding the life experience of patients with spinal stenosis or their opinions on relevant non-surgical treatments, their data was collected from participants in a controlled setting. Therefore, it remains unclear whether patients' or caregivers' concerns/opinions about spinal stenosis would be different in a non-experimental environment...
December 28, 2022: Chiropractic & Manual Therapies
https://read.qxmd.com/read/36419530/feasibility-of-gabapentin-as-an-intervention-for-neurorecovery-after-an-acute-spinal-cord-injury-protocol
#35
JOURNAL ARTICLE
James R Wilson, Samuel Doty, Jordan C Petitt, Mohamed El-Abtah, John J Francis, Megan G Sharpe, Michael L Kelly, Kim D Anderson
INTRODUCTION: This protocol is describing the first ever prospective, mock-efficacy, dose exploration trial design testing the feasibility of administering gabapentin in the acute setting as an intervention for neurorecovery. Gabapentin is an FDA-approved medication for treating seizures and postherpetic neuralgia and is used broadly off-label for neuropathic pain management for many conditions, including spinal cord injury. Emerging data suggests that when given early after spinal cord injury onset and in low-medium doses, gabapentin may have properties that promote recovery of neurological function...
2022: Frontiers in Neurology
https://read.qxmd.com/read/36401511/neck-pain-and-headache-after-pinealectomy-improvement-with-multimodal-chiropractic-therapies
#36
JOURNAL ARTICLE
Eric Chun-Pu Chu, Robert J Trager
BACKGROUND Pineal gland tumors are rare central nervous system tumors, and while neck pain and headaches may be common among those who have had these tumors removed, there is little research regarding management of these symptoms. CASE REPORT A 45-year-old man with a history of pineal germinoma treated with pinealectomy, chemotherapy, radiation therapy, and ventriculoperitoneal shunt placement at age 21 presented with chronic neck pain and headaches, which initially improved following his surgery and concurrent therapies, yet progressively worsened over the following years...
November 19, 2022: American Journal of Case Reports
https://read.qxmd.com/read/36387679/relief-of-postural-orthostatic-tachycardia-syndrome-with-chiropractic-rehabilitation
#37
Eric Chun Pu Chu, Andy Fu Chieh Lin
Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia that's characterised by an abnormal heart rate response to a positional change. A 50-year-old female presented with lightheadedness, palpitation, and neck pain for 3 years. Lightheadedness and palpitation occurred when shifting from a prolonged seated or lying position. Standing radiographs showed spinal misalignment with cervical kyphosis and thoracic scoliosis. Continuous static stress on these minor variants could aggravate biomechanical and autonomic disorder like POTS...
July 2022: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/36319109/bridging-the-gap-gene-therapy-in-a-spinal-muscular-atrophy-type-1-patient
#38
JOURNAL ARTICLE
Gianluca Costamagna, Alessandra Govoni, Adina Wise, Stefania Corti
Molecular therapies exploit understanding of pathogenic mechanisms to reconstitute impaired gene function or manipulate flawed RNA expression. These therapies include 1) RNA interference by antisense oligonucleotides, 2) mRNA modification using small molecules, and 3) gene replacement therapy, the viral-mediated intracellular delivery of exogenous nucleic acids to reverse a genetic defect. Several molecular therapies are approved for treating spinal muscular atrophy (SMA), a recessive genetic disorder caused Survival Motor Neuron (SMN)1 gene mutations...
November 1, 2022: Neurology
https://read.qxmd.com/read/36308289/anaesthesia-for-vascular-emergencies-a-state-of-the-art-review
#39
REVIEW
N Boucher, H Dreksler, J Hooper, S Nagpal, A MirGhassemi, E Miller
In this state-of-the-art review, we discuss the presenting symptoms and management strategies for vascular emergencies. Although vascular emergencies are best treated at a vascular surgical centre, patients may present to any emergency department and may require both immediate management and safe transport to a vascular centre. We describe the surgical and anaesthetic considerations for management of aortic dissection, aortic rupture, carotid endarterectomy, acute limb ischaemia and mesenteric ischaemia. Important issues to consider in aortic dissection are extent of the dissection and surgical need for bypasses in addition to endovascular repair...
February 2023: Anaesthesia
https://read.qxmd.com/read/36254976/vimentin-as-a-potential-target-for-diverse-nervous-system-diseases
#40
REVIEW
Kang-Zhen Chen, Shu-Xian Liu, Yan-Wei Li, Tao He, Jie Zhao, Tao Wang, Xian-Xiu Qiu, Hong-Fu Wu
Vimentin is a major type III intermediate filament protein that plays important roles in several basic cellular functions including cell migration, proliferation, and division. Although vimentin is a cytoplasmic protein, it also exists in the extracellular matrix and at the cell surface. Previous studies have shown that vimentin may exert multiple physiological effects in different nervous system injuries and diseases. For example, the studies of vimentin in spinal cord injury and stroke mainly focus on the formation of reactive astrocytes...
May 2023: Neural Regeneration Research
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